SK288086B6 - Polynucleotide molecule comprising mutated nucleotide sequence of Streptomyces avermitilis aveC allele, vector and host cell, method of making strain of S. avermitilis and process for producing avermectins and final composition - Google Patents
Polynucleotide molecule comprising mutated nucleotide sequence of Streptomyces avermitilis aveC allele, vector and host cell, method of making strain of S. avermitilis and process for producing avermectins and final composition Download PDFInfo
- Publication number
- SK288086B6 SK288086B6 SK139-2002A SK1392002A SK288086B6 SK 288086 B6 SK288086 B6 SK 288086B6 SK 1392002 A SK1392002 A SK 1392002A SK 288086 B6 SK288086 B6 SK 288086B6
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- SK
- Slovakia
- Prior art keywords
- amino acid
- seq
- avec
- avec allele
- nucleotide
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
- C12P19/623—Avermectin; Milbemycin; Ivermectin; C-076
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14864599P | 1999-08-12 | 1999-08-12 | |
| PCT/IB2000/001017 WO2001012821A1 (en) | 1999-08-12 | 2000-07-24 | Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK1392002A3 SK1392002A3 (en) | 2002-12-03 |
| SK288086B6 true SK288086B6 (sk) | 2013-06-03 |
Family
ID=22526696
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK139-2002A SK288086B6 (sk) | 1999-08-12 | 2000-07-24 | Polynucleotide molecule comprising mutated nucleotide sequence of Streptomyces avermitilis aveC allele, vector and host cell, method of making strain of S. avermitilis and process for producing avermectins and final composition |
Country Status (39)
| Country | Link |
|---|---|
| US (3) | US6632673B1 (cs) |
| EP (1) | EP1200606B1 (cs) |
| JP (1) | JP3884651B2 (cs) |
| KR (1) | KR100489856B1 (cs) |
| CN (1) | CN1186446C (cs) |
| AP (1) | AP2002002418A0 (cs) |
| AR (1) | AR022646A1 (cs) |
| AT (1) | ATE341632T1 (cs) |
| AU (1) | AU778837B2 (cs) |
| BG (1) | BG65902B1 (cs) |
| BR (1) | BRPI0013119B8 (cs) |
| CA (1) | CA2380872C (cs) |
| CO (1) | CO5290295A1 (cs) |
| CY (1) | CY1105778T1 (cs) |
| CZ (1) | CZ304402B6 (cs) |
| DE (1) | DE60031126T2 (cs) |
| DK (1) | DK1200606T3 (cs) |
| EA (1) | EA200200056A1 (cs) |
| ES (1) | ES2272299T3 (cs) |
| GT (1) | GT200000136A (cs) |
| HK (1) | HK1046710B (cs) |
| HR (1) | HRP20020130A2 (cs) |
| HU (1) | HU230600B1 (cs) |
| IL (2) | IL147563A0 (cs) |
| IS (1) | IS6250A (cs) |
| MA (1) | MA26813A1 (cs) |
| MX (1) | MXPA02001513A (cs) |
| NO (1) | NO20020664L (cs) |
| NZ (1) | NZ516517A (cs) |
| OA (1) | OA11998A (cs) |
| PA (1) | PA8499501A1 (cs) |
| PE (1) | PE20010690A1 (cs) |
| PL (1) | PL203818B1 (cs) |
| PT (1) | PT1200606E (cs) |
| SK (1) | SK288086B6 (cs) |
| TN (1) | TNSN00171A1 (cs) |
| UY (1) | UY26286A1 (cs) |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60031126T2 (de) * | 1999-08-12 | 2007-02-08 | Pfizer Products Inc., Groton | Streptomyces avermitilis gen zum regulieren des verhältnisses der b2:b1 avermectinen |
| CN1630712B (zh) * | 2002-02-12 | 2011-09-28 | 辉瑞产品公司 | 指导b2:b1除虫菌素比例的除虫链霉菌基因 |
| US7943160B2 (en) * | 2002-05-09 | 2011-05-17 | Scimetrics Limited Corp. | Pest control methods |
| US9493744B2 (en) * | 2012-06-20 | 2016-11-15 | Genentech, Inc. | Methods for viral inactivation and other adventitious agents |
| KR102657859B1 (ko) | 2021-04-07 | 2024-04-16 | 윤재식 | 일체형 내화 소켓 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5238848A (en) | 1987-01-23 | 1993-08-24 | Pfizer Inc | Cultures for production of avermectins |
| US5234831A (en) | 1987-01-23 | 1993-08-10 | Pfizer Inc | Cultures for production of B avermectins |
| US5525506A (en) | 1987-01-23 | 1996-06-11 | Pfizer Inc. | Process for production of avermectins and cultures therefor |
| IN167980B (cs) * | 1987-01-23 | 1991-01-19 | Pfizer | |
| US5240850A (en) | 1987-10-23 | 1993-08-31 | Pfizer Inc. | Cultures for production of avermectin aglycones |
| EP0313297B1 (en) | 1987-10-23 | 1993-05-19 | Pfizer Inc. | Process for production of avermectin aglycones and cultures therefor |
| US5252474A (en) | 1989-03-31 | 1993-10-12 | Merck & Co., Inc. | Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use |
| EP0391594B1 (en) | 1989-03-31 | 1995-10-18 | Merck & Co. Inc. | Cloning genes from streptomyces avermitilis for avermectin biosynthesis and the methods for their use |
| WO1995004150A1 (en) | 1993-07-30 | 1995-02-09 | Pfizer Inc. | Genes encoding branched-chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis |
| FI942725A7 (fi) | 1993-12-16 | 1995-06-17 | Pfizer | Haaraketjuista alfaketohappodenydrogenaasikompleksia koodaavia geenejä Streptomyces avermitiliksesta |
| US6335160B1 (en) | 1995-02-17 | 2002-01-01 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
| US6117679A (en) | 1994-02-17 | 2000-09-12 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
| US5837458A (en) | 1994-02-17 | 1998-11-17 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| US6096548A (en) | 1996-03-25 | 2000-08-01 | Maxygen, Inc. | Method for directing evolution of a virus |
| EP0964922A4 (en) | 1996-09-27 | 2000-10-25 | Maxygen Inc | METHOD FOR OPTIMIZING GENE THERAPY BY REPEATING SEQUENCE MIXING AND SELECTION |
| EP1717322B1 (en) | 1997-01-17 | 2012-07-18 | Codexis Mayflower Holdings, LLC | Evolution of whole cells and organisms by recursive sequence recombination |
| AU1449499A (en) | 1997-10-31 | 1999-05-24 | Maxygen, Incorporated | Modification of virus tropism and host range by viral genome shuffling |
| NZ518657A (en) * | 1998-02-13 | 2003-10-31 | Pfizer Prod Inc | Streptomyces hygroscopicus directing the ratio of B2:B1 avermectins |
| US6248579B1 (en) * | 1998-02-13 | 2001-06-19 | Pfizer Inc | Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins |
| DE60031126T2 (de) * | 1999-08-12 | 2007-02-08 | Pfizer Products Inc., Groton | Streptomyces avermitilis gen zum regulieren des verhältnisses der b2:b1 avermectinen |
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