SK287616B6 - Merkaptoacetylamidové deriváty, spôsob ich prípravy, farmaceutická kompozícia, ktorá ich obsahuje, a ich použitie - Google Patents

Merkaptoacetylamidové deriváty, spôsob ich prípravy, farmaceutická kompozícia, ktorá ich obsahuje, a ich použitie Download PDF

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Publication number
SK287616B6
SK287616B6 SK1255-2003A SK12552003A SK287616B6 SK 287616 B6 SK287616 B6 SK 287616B6 SK 12552003 A SK12552003 A SK 12552003A SK 287616 B6 SK287616 B6 SK 287616B6
Authority
SK
Slovakia
Prior art keywords
group
compound
formula
alkyl
oxo
Prior art date
Application number
SK1255-2003A
Other languages
English (en)
Slovak (sk)
Other versions
SK12552003A3 (sk
Inventor
Gary A. Flynn
Shujaath Mehdi
Jack Roger Koehl
Barbara Ann Anderson
Manfred Gerken
Bernd Jablonka
Heinz-Werner Kleemann
Wolfgang Linz
Werner Seiz
Bernhard Seuring
Original Assignee
Sanofi-Aventis Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0119305.1A external-priority patent/GB0119305D0/en
Application filed by Sanofi-Aventis Deutschland Gmbh filed Critical Sanofi-Aventis Deutschland Gmbh
Publication of SK12552003A3 publication Critical patent/SK12552003A3/sk
Publication of SK287616B6 publication Critical patent/SK287616B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
SK1255-2003A 2001-04-12 2002-04-03 Merkaptoacetylamidové deriváty, spôsob ich prípravy, farmaceutická kompozícia, ktorá ich obsahuje, a ich použitie SK287616B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28330501P 2001-04-12 2001-04-12
GBGB0119305.1A GB0119305D0 (en) 2001-04-12 2001-08-08 Mercaptoacetylamide derivatives,a process for their preparation and their use
PCT/EP2002/003668 WO2002083671A1 (en) 2001-04-12 2002-04-03 Mercaptoacetylamide derivatives, a process for their preparation and their use

Publications (2)

Publication Number Publication Date
SK12552003A3 SK12552003A3 (sk) 2004-03-02
SK287616B6 true SK287616B6 (sk) 2011-04-05

Family

ID=26246410

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1255-2003A SK287616B6 (sk) 2001-04-12 2002-04-03 Merkaptoacetylamidové deriváty, spôsob ich prípravy, farmaceutická kompozícia, ktorá ich obsahuje, a ich použitie

Country Status (27)

Country Link
EP (1) EP1381605B1 (de)
JP (1) JP4392167B2 (de)
CN (1) CN1245404C (de)
AT (1) ATE286898T1 (de)
AU (1) AU2002304804B2 (de)
BG (1) BG66387B1 (de)
BR (1) BR0208889A (de)
CA (1) CA2443488C (de)
CZ (1) CZ299708B6 (de)
DE (1) DE60202602T2 (de)
EE (1) EE05272B1 (de)
ES (1) ES2232752T3 (de)
HK (1) HK1061690A1 (de)
HR (1) HRP20030823B1 (de)
HU (1) HU229612B1 (de)
IL (1) IL158289A0 (de)
MA (1) MA26098A1 (de)
MX (1) MXPA03008613A (de)
NO (1) NO325655B1 (de)
NZ (1) NZ528825A (de)
OA (1) OA12502A (de)
PL (1) PL209338B1 (de)
PT (1) PT1381605E (de)
RU (1) RU2286346C2 (de)
SI (1) SI1381605T1 (de)
SK (1) SK287616B6 (de)
WO (1) WO2002083671A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10229180A1 (de) 2002-06-28 2004-01-29 Aventis Pharma Deutschland Gmbh Verwendung von Vasopeptidase-Inhibitoren bei der Behandlung von metabolischen Erkrankungen, Nephropathie und mit AGE assoziierten Erkrankungen
US8993631B2 (en) 2010-11-16 2015-03-31 Novartis Ag Method of treating contrast-induced nephropathy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2053340C (en) * 1990-10-18 2002-04-02 Timothy P. Burkholder Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
US5430145A (en) * 1990-10-18 1995-07-04 Merrell Dow Pharmaceuticals Inc. Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
DE69220744T2 (de) * 1991-09-27 1997-11-13 Merrell Pharma Inc 2-Substituierte Indan-2-Mercaptoacetylamid-Verbindungen mit Enkephalinase und ACE-Hemmwirkung
WO1994028901A1 (fr) * 1993-06-11 1994-12-22 Eisai Co., Ltd. Derive aminoacide

Also Published As

Publication number Publication date
EE200300500A (et) 2003-12-15
CZ20032722A3 (cs) 2004-01-14
SI1381605T1 (en) 2005-06-30
PL209338B1 (pl) 2011-08-31
IL158289A0 (en) 2004-05-12
RU2286346C2 (ru) 2006-10-27
ATE286898T1 (de) 2005-01-15
EE05272B1 (et) 2010-02-15
HUP0303482A3 (en) 2012-12-28
OA12502A (fr) 2006-05-29
CN1245404C (zh) 2006-03-15
HRP20030823A2 (en) 2005-08-31
RU2003132875A (ru) 2005-03-20
NZ528825A (en) 2005-04-29
NO325655B1 (no) 2008-06-30
BG66387B1 (bg) 2013-11-29
SK12552003A3 (sk) 2004-03-02
PT1381605E (pt) 2005-03-31
HRP20030823B1 (en) 2011-10-31
MA26098A1 (fr) 2004-04-01
EP1381605A1 (de) 2004-01-21
DE60202602T2 (de) 2006-03-23
EP1381605B1 (de) 2005-01-12
CZ299708B6 (cs) 2008-10-29
BR0208889A (pt) 2004-06-29
JP2004525966A (ja) 2004-08-26
NO20034412L (no) 2003-10-02
AU2002304804B2 (en) 2007-05-10
PL363034A1 (en) 2004-11-15
HU229612B1 (en) 2014-03-28
HK1061690A1 (en) 2004-09-30
DE60202602D1 (de) 2005-02-17
HUP0303482A2 (hu) 2004-01-28
NO20034412D0 (no) 2003-10-02
MXPA03008613A (es) 2003-12-08
CA2443488A1 (en) 2002-10-24
ES2232752T3 (es) 2005-06-01
CA2443488C (en) 2011-05-31
JP4392167B2 (ja) 2009-12-24
CN1501926A (zh) 2004-06-02
BG108203A (bg) 2004-12-30
WO2002083671A1 (en) 2002-10-24

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20160403