SK287252B6 - Farmaceutický prípravok s obsahom benzamidového derivátu - Google Patents

Farmaceutický prípravok s obsahom benzamidového derivátu Download PDF

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Publication number
SK287252B6
SK287252B6 SK261-2002A SK2612002A SK287252B6 SK 287252 B6 SK287252 B6 SK 287252B6 SK 2612002 A SK2612002 A SK 2612002A SK 287252 B6 SK287252 B6 SK 287252B6
Authority
SK
Slovakia
Prior art keywords
acid
pharmaceutical preparation
acidic
preparation according
hydrochloride
Prior art date
Application number
SK261-2002A
Other languages
English (en)
Slovak (sk)
Other versions
SK2612002A3 (en
Inventor
Masahiko Ishibashi
Masahiro Sakabe
Ikuo Sakai
Tsuneji Suzuki
Tomoyuki Ando
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of SK2612002A3 publication Critical patent/SK2612002A3/sk
Publication of SK287252B6 publication Critical patent/SK287252B6/sk

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SK261-2002A 1999-08-30 2000-08-29 Farmaceutický prípravok s obsahom benzamidového derivátu SK287252B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP24244499A JP2001081031A (ja) 1999-08-30 1999-08-30 溶解性および経口吸収性を改善したベンズアミド誘導体含有製剤
PCT/EP2000/008421 WO2001016106A1 (en) 1999-08-30 2000-08-29 Benzamide formulation with histone deacetylase inhibitor activity

Publications (2)

Publication Number Publication Date
SK2612002A3 SK2612002A3 (en) 2002-09-10
SK287252B6 true SK287252B6 (sk) 2010-04-07

Family

ID=17089193

Family Applications (1)

Application Number Title Priority Date Filing Date
SK261-2002A SK287252B6 (sk) 1999-08-30 2000-08-29 Farmaceutický prípravok s obsahom benzamidového derivátu

Country Status (32)

Country Link
US (1) US6638530B1 (bg)
EP (1) EP1208086B1 (bg)
JP (2) JP2001081031A (bg)
KR (1) KR100712640B1 (bg)
CN (1) CN1147472C (bg)
AR (1) AR025434A1 (bg)
AT (1) ATE318258T1 (bg)
AU (1) AU773617B2 (bg)
BG (1) BG65544B1 (bg)
BR (1) BR0013648A (bg)
CA (1) CA2382886C (bg)
CZ (1) CZ301737B6 (bg)
DE (1) DE60026144T2 (bg)
DK (1) DK1208086T3 (bg)
EE (1) EE05063B1 (bg)
ES (1) ES2259289T3 (bg)
HK (1) HK1046277B (bg)
HR (1) HRP20020182B1 (bg)
HU (1) HUP0203330A3 (bg)
IL (2) IL148357A0 (bg)
MX (1) MXPA02002090A (bg)
NO (1) NO322532B1 (bg)
NZ (1) NZ517520A (bg)
PL (1) PL201274B1 (bg)
PT (1) PT1208086E (bg)
RU (1) RU2260428C2 (bg)
SI (1) SI1208086T1 (bg)
SK (1) SK287252B6 (bg)
TW (1) TWI268778B (bg)
UA (1) UA72541C2 (bg)
WO (1) WO2001016106A1 (bg)
ZA (1) ZA200201424B (bg)

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US6706686B2 (en) 2001-09-27 2004-03-16 The Regents Of The University Of Colorado Inhibition of histone deacetylase as a treatment for cardiac hypertrophy
AU2002340253C1 (en) 2001-10-16 2011-03-31 Sloan-Kettering Institute For Cancer Research Treatment of neurodegenerative diseases and cancer of the brain
WO2003070691A1 (fr) * 2002-02-21 2003-08-28 Osaka Industrial Promotion Organization Derive de n-hydroxycarboxamide
US7148257B2 (en) 2002-03-04 2006-12-12 Merck Hdac Research, Llc Methods of treating mesothelioma with suberoylanilide hydroxamic acid
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US7456219B2 (en) 2002-03-04 2008-11-25 Merck Hdac Research, Llc Polymorphs of suberoylanilide hydroxamic acid
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US7604939B2 (en) * 2005-03-01 2009-10-20 The Regents Of The University Of Michigan Methods of identifying active BRM expression-promoting HDAC inhibitors
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US20100152188A1 (en) * 2005-08-05 2010-06-17 Akella Satya Surya Visweswara Srinivas Novel Heterocyclic Compounds
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EP2040731A4 (en) * 2006-06-09 2010-05-19 Merrion Res Iii Ltd SOLID DOSAGE FORM FOR ORAL ADMINISTRATION CONTAINING AN ACTIVATOR
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Also Published As

Publication number Publication date
TWI268778B (en) 2006-12-21
JP2001081031A (ja) 2001-03-27
NO322532B1 (no) 2006-10-23
DE60026144D1 (de) 2006-04-27
RU2260428C2 (ru) 2005-09-20
IL148357A (en) 2006-12-10
EP1208086B1 (en) 2006-02-22
AU6841600A (en) 2001-03-26
EE05063B1 (et) 2008-08-15
US6638530B1 (en) 2003-10-28
BR0013648A (pt) 2002-05-07
HUP0203330A2 (hu) 2003-02-28
BG65544B1 (bg) 2008-11-28
JP2003508386A (ja) 2003-03-04
NZ517520A (en) 2003-05-30
EP1208086A1 (en) 2002-05-29
CA2382886A1 (en) 2001-03-08
WO2001016106A1 (en) 2001-03-08
CN1147472C (zh) 2004-04-28
HRP20020182B1 (en) 2007-08-31
ATE318258T1 (de) 2006-03-15
MXPA02002090A (es) 2003-08-20
ZA200201424B (en) 2002-11-27
AR025434A1 (es) 2002-11-27
SK2612002A3 (en) 2002-09-10
CZ2002724A3 (cs) 2002-07-17
HK1046277A1 (en) 2003-01-03
HK1046277B (zh) 2004-11-26
EE200200097A (et) 2003-04-15
DE60026144T2 (de) 2006-11-16
UA72541C2 (en) 2005-03-15
AU773617B2 (en) 2004-05-27
PL353063A1 (en) 2003-10-06
HUP0203330A3 (en) 2004-03-01
ES2259289T3 (es) 2006-10-01
CZ301737B6 (cs) 2010-06-09
NO20020952D0 (no) 2002-02-27
PL201274B1 (pl) 2009-03-31
HRP20020182A2 (en) 2004-02-29
NO20020952L (no) 2002-03-20
DK1208086T3 (da) 2006-06-19
SI1208086T1 (sl) 2006-08-31
CA2382886C (en) 2009-06-09
PT1208086E (pt) 2006-07-31
CN1371366A (zh) 2002-09-25
KR100712640B1 (ko) 2007-05-02
BG106439A (bg) 2002-11-29
KR20020023424A (ko) 2002-03-28
IL148357A0 (en) 2002-09-12

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MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20110829