SK287139B6 - Spôsob prípravy citalopramu - Google Patents

Spôsob prípravy citalopramu Download PDF

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Publication number
SK287139B6
SK287139B6 SK924-2001A SK9242001A SK287139B6 SK 287139 B6 SK287139 B6 SK 287139B6 SK 9242001 A SK9242001 A SK 9242001A SK 287139 B6 SK287139 B6 SK 287139B6
Authority
SK
Slovakia
Prior art keywords
formula
compound
fluorophenyl
prepared
process according
Prior art date
Application number
SK924-2001A
Other languages
English (en)
Slovak (sk)
Other versions
SK9242001A3 (en
Inventor
Michael Harold Rock
Hans Petersen
Peter Ellegaard
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of SK9242001A3 publication Critical patent/SK9242001A3/sk
Publication of SK287139B6 publication Critical patent/SK287139B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SK924-2001A 1999-10-25 1999-10-25 Spôsob prípravy citalopramu SK287139B6 (sk)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ES200150056A ES2169709A1 (es) 1999-10-25 1999-10-25 Metodo para la preparacion de citalopram
PCT/DK1999/000581 WO2000012044A2 (en) 1999-10-25 1999-10-25 Method for the preparation of citalopram
CH02004/01A CH692298A5 (de) 1999-10-25 1999-10-25 Verfahren zur Herstellung von Zwischenstufen für die Citalopramsynthese sowie zur Herstellung von Escitalopram.
CH01179/01A CH692421A5 (de) 1999-10-25 1999-10-25 Verfahren zur Herstellung von Citalopram.

Publications (2)

Publication Number Publication Date
SK9242001A3 SK9242001A3 (en) 2001-12-03
SK287139B6 true SK287139B6 (sk) 2010-01-07

Family

ID=27429871

Family Applications (1)

Application Number Title Priority Date Filing Date
SK924-2001A SK287139B6 (sk) 1999-10-25 1999-10-25 Spôsob prípravy citalopramu

Country Status (11)

Country Link
US (1) US6407267B1 (xx)
EP (1) EP1228056B1 (xx)
AU (1) AU742554B2 (xx)
CH (2) CH692421A5 (xx)
DK (1) DK200100959A (xx)
ES (2) ES2169709A1 (xx)
GB (1) GB2360281B (xx)
NO (1) NO325185B1 (xx)
SK (1) SK287139B6 (xx)
TR (1) TR200101874T1 (xx)
WO (1) WO2000012044A2 (xx)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000023431A1 (en) 1998-10-20 2000-04-27 H. Lundbeck A/S Method for the preparation of citalopram
CZ300408B6 (cs) 1998-12-23 2009-05-13 H. Lundbeck A/S Zpusob výroby 5-kyanoftalidu
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
PL198024B1 (pl) 1999-04-14 2008-05-30 Lundbeck & Co As H Sposób wytwarzania citalopramu, związki pośrednie i ich zastosowanie do wytwarzania citalopramu
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
TR200101874T1 (tr) 1999-10-25 2002-02-21 H. Lundbeck A/S Sitalopram hazırlanması için yöntem
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
ATE261953T1 (de) 1999-12-28 2004-04-15 Lundbeck & Co As H Verfahren zur herstellung von citalopram
TR200201688T2 (tr) 1999-12-30 2002-11-21 H. Lundbeck A/S Sitalopram hazırlama yöntemi.
EA005134B1 (ru) 2000-01-14 2004-12-30 Х.Лундбекк А/С Способ получения 5-цианофталида
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
EA200200968A1 (ru) 2000-03-13 2003-02-27 Х.Лундбекк А/С Поэтапное алкилирование 5-замещенных 1-(4-фторфенил)-1,3-дигидроизобензофуранов
TR200202166T2 (tr) 2000-03-13 2002-12-23 H. Lndbeck A/S Sitalopramın preparasyon metodu
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
CA2402557A1 (en) 2000-03-14 2001-09-20 Hans Petersen Method for the preparation of citalopram
CA2402869A1 (en) * 2000-03-16 2001-09-20 Hans Petersen Method for the preparation of 5-cyano-1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
CA2354880C (en) 2000-08-18 2003-06-03 H. Lundbeck A/S Method for the preparation of citalopram
KR100439329B1 (ko) 2000-12-22 2004-07-07 하. 룬트벡 아크티에 셀스카브 순수한 시탈로프람의 제조방법
AU3920201A (en) 2000-12-28 2001-07-09 H. Lundbeck A/S Process for the preparation of pure citalopram
CA2435925A1 (en) 2001-01-30 2002-08-08 Orion Corporation Fermion Process for the preparation of 1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
FI20021421A0 (fi) * 2002-07-30 2002-07-30 Orion Corp Fermion Valmistusmenetelmä
PE20040991A1 (es) * 2002-08-12 2004-12-27 Lundbeck & Co As H Separacion de intermediarios para la preparacion de escitalopram
WO2004085416A1 (en) * 2003-03-24 2004-10-07 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
TWI339651B (en) 2004-02-12 2011-04-01 Lundbeck & Co As H Method for the separation of intermediates which may be used for the preparation of escitalopram
GB0601286D0 (en) * 2006-01-23 2006-03-01 Sandoz Ag Asymmetric synthesis
US9339500B2 (en) * 2008-03-04 2016-05-17 Intra-Cellular Therapies, Inc. Methods of treating vasomotor symptoms

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143702A (xx) 1965-03-18
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
JP3526581B2 (ja) 1997-07-08 2004-05-17 ハー・ルンドベック・アクティーゼルスカブ シタロプラムの製造方法
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
DE69714480T2 (de) 1997-11-11 2003-03-06 Lundbeck & Co As H Verfahren zur Herstellung von Citalopram
WO2000023431A1 (en) 1998-10-20 2000-04-27 H. Lundbeck A/S Method for the preparation of citalopram
CZ300408B6 (cs) 1998-12-23 2009-05-13 H. Lundbeck A/S Zpusob výroby 5-kyanoftalidu
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
PL198024B1 (pl) 1999-04-14 2008-05-30 Lundbeck & Co As H Sposób wytwarzania citalopramu, związki pośrednie i ich zastosowanie do wytwarzania citalopramu
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
TR200101874T1 (tr) 1999-10-25 2002-02-21 H. Lundbeck A/S Sitalopram hazırlanması için yöntem
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
JP4025501B2 (ja) 2000-03-03 2007-12-19 株式会社ソニー・コンピュータエンタテインメント 楽音発生装置
KR100439329B1 (ko) 2000-12-22 2004-07-07 하. 룬트벡 아크티에 셀스카브 순수한 시탈로프람의 제조방법
AU3920201A (en) 2000-12-28 2001-07-09 H. Lundbeck A/S Process for the preparation of pure citalopram

Also Published As

Publication number Publication date
GB2360281B (en) 2002-01-16
ES2229774T3 (es) 2005-04-16
EP1228056A2 (en) 2002-08-07
TR200101874T1 (tr) 2002-02-21
NO20013185L (no) 2001-08-24
NO20013185D0 (no) 2001-06-25
SK9242001A3 (en) 2001-12-03
AU742554B2 (en) 2002-01-03
WO2000012044A2 (en) 2000-03-09
WO2000012044A3 (en) 2000-08-03
DK200100959A (da) 2001-07-11
AU6326599A (en) 2000-03-21
ES2169709A1 (es) 2002-07-01
CH692421A5 (de) 2002-06-14
US20020035277A1 (en) 2002-03-21
CH692298A5 (de) 2002-04-30
NO325185B1 (no) 2008-02-11
GB2360281A (en) 2001-09-19
GB0115030D0 (en) 2001-08-08
EP1228056B1 (en) 2004-09-22
US6407267B1 (en) 2002-06-18

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20121025