SK286320B6 - Imidazole derivative, method for its preparing and use and pharmaceutical compositions containing it - Google Patents

Imidazole derivative, method for its preparing and use and pharmaceutical compositions containing it Download PDF

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Publication number
SK286320B6
SK286320B6 SK998-2002A SK9982002A SK286320B6 SK 286320 B6 SK286320 B6 SK 286320B6 SK 9982002 A SK9982002 A SK 9982002A SK 286320 B6 SK286320 B6 SK 286320B6
Authority
SK
Slovakia
Prior art keywords
alkyl
compound
compound according
imidazole
phenyl
Prior art date
Application number
SK998-2002A
Other languages
English (en)
Slovak (sk)
Other versions
SK9982002A3 (en
Inventor
Paavo Huhtala
Arto Karjalainen
Antti Haapalinna
Jyrki Lehtimaki
Arja Karjalainen
Raimo Virtanen
Original Assignee
Orion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corp filed Critical Orion Corp
Publication of SK9982002A3 publication Critical patent/SK9982002A3/sk
Publication of SK286320B6 publication Critical patent/SK286320B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK998-2002A 2000-01-14 2001-01-12 Imidazole derivative, method for its preparing and use and pharmaceutical compositions containing it SK286320B6 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20000073A FI20000073A0 (fi) 2000-01-14 2000-01-14 Uusia imidatsolijohdannaisia
PCT/FI2001/000030 WO2001051472A1 (en) 2000-01-14 2001-01-12 New imidazole derivatives

Publications (2)

Publication Number Publication Date
SK9982002A3 SK9982002A3 (en) 2003-03-04
SK286320B6 true SK286320B6 (en) 2008-07-07

Family

ID=8557065

Family Applications (1)

Application Number Title Priority Date Filing Date
SK998-2002A SK286320B6 (en) 2000-01-14 2001-01-12 Imidazole derivative, method for its preparing and use and pharmaceutical compositions containing it

Country Status (30)

Country Link
EP (1) EP1261588B1 (xx)
JP (1) JP2003519688A (xx)
KR (1) KR20020084091A (xx)
CN (1) CN1187336C (xx)
AR (1) AR029432A1 (xx)
AT (1) ATE280161T1 (xx)
AU (1) AU769896B2 (xx)
BR (1) BR0107644A (xx)
CA (1) CA2397283A1 (xx)
CZ (1) CZ20022358A3 (xx)
DE (1) DE60106572T2 (xx)
DK (1) DK1261588T3 (xx)
EE (1) EE200200389A (xx)
ES (1) ES2228884T3 (xx)
FI (1) FI20000073A0 (xx)
GC (1) GC0000218A (xx)
HK (1) HK1049999B (xx)
HU (1) HUP0301008A3 (xx)
IL (1) IL150506A0 (xx)
MX (1) MXPA02006872A (xx)
NO (1) NO323117B1 (xx)
NZ (1) NZ519919A (xx)
PE (1) PE20011230A1 (xx)
PL (1) PL207281B1 (xx)
PT (1) PT1261588E (xx)
RU (1) RU2265598C2 (xx)
SI (1) SI1261588T1 (xx)
SK (1) SK286320B6 (xx)
WO (1) WO2001051472A1 (xx)
ZA (1) ZA200205301B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20002756A0 (fi) * 2000-12-15 2000-12-15 Orion Yhtymae Oyj Uusi hoitomenetelmä
TW200930291A (en) * 2002-04-29 2009-07-16 Bayer Cropscience Ag Pesticidal heterocycles
FI20022159A0 (fi) * 2002-12-05 2002-12-05 Orion Corp Uusia farmaseuttisia yhdisteitä
DE102004035322A1 (de) * 2004-07-21 2006-02-16 Universität des Saarlandes Selektive Hemmstoffe humaner Corticoidsynthasen
ATE546437T1 (de) 2006-10-19 2012-03-15 Hoffmann La Roche Aminomethyl-4-imidazole
JP2010510184A (ja) * 2006-11-16 2010-04-02 エフ．ホフマン−ラ ロシュ アーゲー 置換４−イミダゾール類
US20080146523A1 (en) 2006-12-18 2008-06-19 Guido Galley Imidazole derivatives
AR090557A1 (es) * 2012-04-02 2014-11-19 Orion Corp DERIVADOS IMIDAZOLICOS AGONISTAS ADRENERGICOS a2

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2225782A (en) * 1988-12-09 1990-06-13 Farmos Group Limited Imidazole derivatives useful for treatment of diabetes
GB2244431A (en) * 1990-05-31 1991-12-04 Farmos Oy Treatment of age related memory impairment and other cognitive disorders
US5541211A (en) * 1991-06-18 1996-07-30 Orion-Yhtyma Oy Administration of atipamezole to elicit a yohimbine-like alpha-adrenoreceptor antagonistic noradrenergic transmission
GB9127050D0 (en) * 1991-12-20 1992-02-19 Orion Yhtymae Oy Substituted imidazole derivatives and their preparation and use
GB9520150D0 (en) * 1995-10-03 1995-12-06 Orion Yhtymae Oy New imidazole derivatives
RU2235092C2 (ru) * 1997-12-04 2004-08-27 Оллерган Инк. Замещенные производные имидазола, способ введения активного соединения и способ лечения на основе этих соединений
US6503935B1 (en) * 1998-08-07 2003-01-07 Abbott Laboratories Imidazoles and related compounds as α1A agonists
TWI283669B (en) * 1999-06-10 2007-07-11 Allergan Inc Compounds and method of treatment having agonist-like activity selective at alpha 2B or 2B/2C adrenergic receptors

Also Published As

Publication number Publication date
CA2397283A1 (en) 2001-07-19
KR20020084091A (ko) 2002-11-04
NZ519919A (en) 2003-10-31
CN1187336C (zh) 2005-02-02
AR029432A1 (es) 2003-06-25
ES2228884T3 (es) 2005-04-16
EP1261588B1 (en) 2004-10-20
EP1261588A1 (en) 2002-12-04
IL150506A0 (en) 2003-02-12
EE200200389A (et) 2003-10-15
WO2001051472A1 (en) 2001-07-19
HUP0301008A3 (en) 2004-01-28
FI20000073A0 (fi) 2000-01-14
NO323117B1 (no) 2007-01-08
WO2001051472A9 (en) 2003-01-23
NO20023298D0 (no) 2002-07-08
RU2002121777A (ru) 2004-01-10
CN1395567A (zh) 2003-02-05
SK9982002A3 (en) 2003-03-04
BR0107644A (pt) 2002-10-08
DK1261588T3 (da) 2005-02-14
RU2265598C2 (ru) 2005-12-10
SI1261588T1 (en) 2005-02-28
AU2853201A (en) 2001-07-24
MXPA02006872A (es) 2003-01-28
GC0000218A (en) 2006-03-29
AU769896B2 (en) 2004-02-05
NO20023298L (no) 2002-09-06
PE20011230A1 (es) 2001-12-08
HK1049999A1 (en) 2003-06-06
ZA200205301B (en) 2003-10-02
ATE280161T1 (de) 2004-11-15
DE60106572T2 (de) 2006-02-09
HK1049999B (zh) 2005-05-13
CZ20022358A3 (cs) 2007-12-19
JP2003519688A (ja) 2003-06-24
PL207281B1 (pl) 2010-11-30
HUP0301008A2 (hu) 2003-10-28
PL356884A1 (en) 2004-07-12
PT1261588E (pt) 2005-02-28
DE60106572D1 (de) 2004-11-25

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20110112