BR0107644A - Derivados de imidazol - Google Patents

Derivados de imidazol

Info

Publication number
BR0107644A
BR0107644A BR0107644-2A BR0107644A BR0107644A BR 0107644 A BR0107644 A BR 0107644A BR 0107644 A BR0107644 A BR 0107644A BR 0107644 A BR0107644 A BR 0107644A
Authority
BR
Brazil
Prior art keywords
imidazole derivatives
formula
derivative
imidazole
affinity
Prior art date
Application number
BR0107644-2A
Other languages
English (en)
Inventor
Paavo Huhtala
Arto Karjalainen
Antti Haapalinna
Jyrki Lehtimaeki
Arja Karjalainen
Raimo Virtanen
Original Assignee
Orion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corp filed Critical Orion Corp
Publication of BR0107644A publication Critical patent/BR0107644A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Reproductive Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"DERIVADOS DE IMIDAZOL". Descreve-se um derivado de imidazol da fórmula (I) ou um seu sal ou derivado de uso farmacêutico. Os compostos da fórmula (I) apresentam afinidade por adrenoceptores alfa2.
BR0107644-2A 2000-01-14 2001-01-12 Derivados de imidazol BR0107644A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20000073A FI20000073A0 (fi) 2000-01-14 2000-01-14 Uusia imidatsolijohdannaisia
PCT/FI2001/000030 WO2001051472A1 (en) 2000-01-14 2001-01-12 New imidazole derivatives

Publications (1)

Publication Number Publication Date
BR0107644A true BR0107644A (pt) 2002-10-08

Family

ID=8557065

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0107644-2A BR0107644A (pt) 2000-01-14 2001-01-12 Derivados de imidazol

Country Status (30)

Country Link
EP (1) EP1261588B1 (pt)
JP (1) JP2003519688A (pt)
KR (1) KR20020084091A (pt)
CN (1) CN1187336C (pt)
AR (1) AR029432A1 (pt)
AT (1) ATE280161T1 (pt)
AU (1) AU769896B2 (pt)
BR (1) BR0107644A (pt)
CA (1) CA2397283A1 (pt)
CZ (1) CZ20022358A3 (pt)
DE (1) DE60106572T2 (pt)
DK (1) DK1261588T3 (pt)
EE (1) EE200200389A (pt)
ES (1) ES2228884T3 (pt)
FI (1) FI20000073A0 (pt)
GC (1) GC0000218A (pt)
HK (1) HK1049999B (pt)
HU (1) HUP0301008A3 (pt)
IL (1) IL150506A0 (pt)
MX (1) MXPA02006872A (pt)
NO (1) NO323117B1 (pt)
NZ (1) NZ519919A (pt)
PE (1) PE20011230A1 (pt)
PL (1) PL207281B1 (pt)
PT (1) PT1261588E (pt)
RU (1) RU2265598C2 (pt)
SI (1) SI1261588T1 (pt)
SK (1) SK286320B6 (pt)
WO (1) WO2001051472A1 (pt)
ZA (1) ZA200205301B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20002756A0 (fi) * 2000-12-15 2000-12-15 Orion Yhtymae Oyj Uusi hoitomenetelmä
TW200930291A (en) * 2002-04-29 2009-07-16 Bayer Cropscience Ag Pesticidal heterocycles
FI20022159A0 (fi) * 2002-12-05 2002-12-05 Orion Corp Uusia farmaseuttisia yhdisteitä
DE102004035322A1 (de) * 2004-07-21 2006-02-16 Universität des Saarlandes Selektive Hemmstoffe humaner Corticoidsynthasen
ATE546437T1 (de) 2006-10-19 2012-03-15 Hoffmann La Roche Aminomethyl-4-imidazole
JP2010510184A (ja) * 2006-11-16 2010-04-02 エフ．ホフマン−ラ ロシュ アーゲー 置換４−イミダゾール類
US20080146523A1 (en) 2006-12-18 2008-06-19 Guido Galley Imidazole derivatives
AR090557A1 (es) * 2012-04-02 2014-11-19 Orion Corp DERIVADOS IMIDAZOLICOS AGONISTAS ADRENERGICOS a2

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2225782A (en) * 1988-12-09 1990-06-13 Farmos Group Limited Imidazole derivatives useful for treatment of diabetes
GB2244431A (en) * 1990-05-31 1991-12-04 Farmos Oy Treatment of age related memory impairment and other cognitive disorders
US5541211A (en) * 1991-06-18 1996-07-30 Orion-Yhtyma Oy Administration of atipamezole to elicit a yohimbine-like alpha-adrenoreceptor antagonistic noradrenergic transmission
GB9127050D0 (en) * 1991-12-20 1992-02-19 Orion Yhtymae Oy Substituted imidazole derivatives and their preparation and use
GB9520150D0 (en) * 1995-10-03 1995-12-06 Orion Yhtymae Oy New imidazole derivatives
RU2235092C2 (ru) * 1997-12-04 2004-08-27 Оллерган Инк. Замещенные производные имидазола, способ введения активного соединения и способ лечения на основе этих соединений
US6503935B1 (en) * 1998-08-07 2003-01-07 Abbott Laboratories Imidazoles and related compounds as α1A agonists
TWI283669B (en) * 1999-06-10 2007-07-11 Allergan Inc Compounds and method of treatment having agonist-like activity selective at alpha 2B or 2B/2C adrenergic receptors

Also Published As

Publication number Publication date
CA2397283A1 (en) 2001-07-19
KR20020084091A (ko) 2002-11-04
NZ519919A (en) 2003-10-31
CN1187336C (zh) 2005-02-02
AR029432A1 (es) 2003-06-25
ES2228884T3 (es) 2005-04-16
EP1261588B1 (en) 2004-10-20
EP1261588A1 (en) 2002-12-04
IL150506A0 (en) 2003-02-12
EE200200389A (et) 2003-10-15
WO2001051472A1 (en) 2001-07-19
HUP0301008A3 (en) 2004-01-28
FI20000073A0 (fi) 2000-01-14
NO323117B1 (no) 2007-01-08
WO2001051472A9 (en) 2003-01-23
NO20023298D0 (no) 2002-07-08
RU2002121777A (ru) 2004-01-10
CN1395567A (zh) 2003-02-05
SK9982002A3 (en) 2003-03-04
DK1261588T3 (da) 2005-02-14
SK286320B6 (en) 2008-07-07
RU2265598C2 (ru) 2005-12-10
SI1261588T1 (en) 2005-02-28
AU2853201A (en) 2001-07-24
MXPA02006872A (es) 2003-01-28
GC0000218A (en) 2006-03-29
AU769896B2 (en) 2004-02-05
NO20023298L (no) 2002-09-06
PE20011230A1 (es) 2001-12-08
HK1049999A1 (en) 2003-06-06
ZA200205301B (en) 2003-10-02
ATE280161T1 (de) 2004-11-15
DE60106572T2 (de) 2006-02-09
HK1049999B (zh) 2005-05-13
CZ20022358A3 (cs) 2007-12-19
JP2003519688A (ja) 2003-06-24
PL207281B1 (pl) 2010-11-30
HUP0301008A2 (hu) 2003-10-28
PL356884A1 (en) 2004-07-12
PT1261588E (pt) 2005-02-28
DE60106572D1 (de) 2004-11-25

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

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