SK286158B6 - Spirozlúčenina, spôsob a medziprodukt na jej prípravu, jej použitie, farmaceutická kompozícia s jejobsahom a spôsob jej prípravy - Google Patents
Spirozlúčenina, spôsob a medziprodukt na jej prípravu, jej použitie, farmaceutická kompozícia s jejobsahom a spôsob jej prípravy Download PDFInfo
- Publication number
- SK286158B6 SK286158B6 SK814-2001A SK8142001A SK286158B6 SK 286158 B6 SK286158 B6 SK 286158B6 SK 8142001 A SK8142001 A SK 8142001A SK 286158 B6 SK286158 B6 SK 286158B6
- Authority
- SK
- Slovakia
- Prior art keywords
- alkyl
- formula
- hydrogen
- alkyloxycarbonyl
- piperidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/20—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/20—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/20—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Dental Preparations (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98204347 | 1998-12-19 | ||
| PCT/EP1999/010176 WO2000037470A1 (en) | 1998-12-19 | 1999-12-15 | Antihistaminic spiro compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK8142001A3 SK8142001A3 (en) | 2002-04-04 |
| SK286158B6 true SK286158B6 (sk) | 2008-04-07 |
Family
ID=8234498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK814-2001A SK286158B6 (sk) | 1998-12-19 | 1999-12-15 | Spirozlúčenina, spôsob a medziprodukt na jej prípravu, jej použitie, farmaceutická kompozícia s jejobsahom a spôsob jej prípravy |
Country Status (37)
| Country | Link |
|---|---|
| US (2) | US7148214B1 (xx) |
| EP (1) | EP1144411B1 (xx) |
| JP (1) | JP4601175B2 (xx) |
| KR (1) | KR100598725B1 (xx) |
| CN (1) | CN1258533C (xx) |
| AR (1) | AR021888A1 (xx) |
| AT (1) | ATE294178T1 (xx) |
| AU (1) | AU764820C (xx) |
| BG (1) | BG65133B1 (xx) |
| BR (1) | BR9916371A (xx) |
| CA (1) | CA2355939C (xx) |
| CO (1) | CO5140116A1 (xx) |
| CZ (1) | CZ301953B6 (xx) |
| DE (1) | DE69925036T2 (xx) |
| DK (1) | DK1144411T3 (xx) |
| EA (1) | EA004500B1 (xx) |
| EE (1) | EE04917B1 (xx) |
| EG (1) | EG24605A (xx) |
| ES (1) | ES2242443T3 (xx) |
| HK (1) | HK1043128B (xx) |
| HR (1) | HRP20010453B1 (xx) |
| HU (1) | HU229406B1 (xx) |
| ID (1) | ID29268A (xx) |
| IL (1) | IL143767A0 (xx) |
| MY (1) | MY129663A (xx) |
| NO (1) | NO318891B1 (xx) |
| NZ (1) | NZ512870A (xx) |
| PL (1) | PL196262B1 (xx) |
| PT (1) | PT1144411E (xx) |
| SA (1) | SA00210113B1 (xx) |
| SI (1) | SI1144411T1 (xx) |
| SK (1) | SK286158B6 (xx) |
| TR (1) | TR200101711T2 (xx) |
| TW (1) | TWI250981B (xx) |
| UA (1) | UA74537C2 (xx) |
| WO (1) | WO2000037470A1 (xx) |
| ZA (1) | ZA200104977B (xx) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2278065T3 (es) | 2001-10-15 | 2007-08-01 | Janssen Pharmaceutica N.V. | Nuevos derivados de 4-fenil-4-(1h-imidazol-2-il)-piperidina sustituida y su uso como agonistas selectivos de opioides delta no peptidos. |
| UA75980C2 (en) * | 2001-10-15 | 2006-06-15 | Janssen Pharmaceutica Nv | Substituted 4-pheny1-4-[1h-imidazol-2-yl] piperidine derivative for reducing ischaemic damages |
| US7412768B2 (en) * | 2004-05-11 | 2008-08-19 | Alliss George E | Invertible trimmer line spool for a vegetation trimmer apparatus |
| EP1795527B1 (en) * | 2004-09-07 | 2009-04-22 | Banyu Pharmaceutical Co., Ltd. | Carbamoyl-substituted spiro derivative |
| ES2447590T3 (es) | 2008-04-29 | 2014-03-12 | Novartis Ag | Derivados de espiro-indol para el tratamiento de enfermedades parasitarias |
| US8940742B2 (en) | 2012-04-10 | 2015-01-27 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| EP3052485B1 (en) | 2013-10-04 | 2021-07-28 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| US9751888B2 (en) | 2013-10-04 | 2017-09-05 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| EP4066834A1 (en) | 2014-03-19 | 2022-10-05 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds for use in the treatment of pi3k-gamma mediated disorders |
| BR112017003745A2 (pt) | 2014-08-29 | 2017-12-05 | Tes Pharma S R L | inibidores de semialdeído descarboxilase de ácido alfa-amino-beta-carboximucônico |
| US9708348B2 (en) | 2014-10-03 | 2017-07-18 | Infinity Pharmaceuticals, Inc. | Trisubstituted bicyclic heterocyclic compounds with kinase activities and uses thereof |
| EP3350183A1 (en) | 2015-09-14 | 2018-07-25 | Infinity Pharmaceuticals, Inc. | Solid forms of isoquinolinone derivatives, process of making, compositions comprising, and methods of using the same |
| WO2017088080A1 (es) | 2015-11-25 | 2017-06-01 | Natural Response S.A. | Método para la obtención de saponinas a partir de plantas |
| US10759806B2 (en) | 2016-03-17 | 2020-09-01 | Infinity Pharmaceuticals, Inc. | Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as PI3K kinase inhibitors |
| US10919914B2 (en) | 2016-06-08 | 2021-02-16 | Infinity Pharmaceuticals, Inc. | Heterocyclic compounds and uses thereof |
| KR20240052355A (ko) | 2022-10-14 | 2024-04-23 | 지이 일렉트리컬 엔지니어링 컴퍼니., 리미티드. | 여과 장치용 커버 |
| KR20240052354A (ko) | 2022-10-14 | 2024-04-23 | 지이 일렉트리컬 엔지니어링 컴퍼니., 리미티드. | 여과 장치 |
| CN117624052B (zh) * | 2024-01-26 | 2024-04-12 | 四川益能康生环保科技有限公司 | 一种用于捕集二氧化碳的离子液体及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4464380A (en) | 1983-05-25 | 1984-08-07 | Pfizer Inc. | Imidazolidinedione derivatives |
| PH30434A (en) | 1989-04-07 | 1997-05-09 | Janssen Pharmaceutica Nv | Hydroxyalkylfuranyl derivatives |
| WO1992006981A1 (en) * | 1990-10-10 | 1992-04-30 | Schering Corporation | Substituted imidazobenzazepines and imidazopyridoazepines |
| IL101851A (en) * | 1991-06-13 | 1996-05-14 | Janssen Pharmaceutica Nv | History 01 -) 4 - Pipridinyl - and Pipridinylidene (- Imidazo] A-1,2 [Pirolo, Thiano or Purano (] 3,2 [Azpin, their preparation and pharmaceutical preparations containing them and composition |
| IL101850A (en) * | 1991-06-13 | 1996-01-31 | Janssen Pharmaceutica Nv | History 11-) 4-Pipridinyl (-Imidazo] B-1, 2 [] 3 [Benzazepine, their preparation and pharmaceutical preparations containing them |
| US5106844A (en) * | 1991-09-10 | 1992-04-21 | Sterling Drug Inc. | Imidazo[2,2-b][3]benzazepine and pyrimido[2,1-b][3]benzazepine antiarrhythmic agents |
| TW382017B (en) | 1995-12-27 | 2000-02-11 | Janssen Pharmaceutica Nv | 1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives |
-
1999
- 1999-12-15 BR BR9916371-3A patent/BR9916371A/pt not_active Application Discontinuation
- 1999-12-15 CN CNB998147052A patent/CN1258533C/zh not_active Expired - Lifetime
- 1999-12-15 HU HU0104779A patent/HU229406B1/hu unknown
- 1999-12-15 AU AU30412/00A patent/AU764820C/en not_active Expired
- 1999-12-15 ID IDW00200101298A patent/ID29268A/id unknown
- 1999-12-15 DK DK99964625T patent/DK1144411T3/da active
- 1999-12-15 WO PCT/EP1999/010176 patent/WO2000037470A1/en active IP Right Grant
- 1999-12-15 KR KR1020017005016A patent/KR100598725B1/ko active IP Right Grant
- 1999-12-15 TR TR2001/01711T patent/TR200101711T2/xx unknown
- 1999-12-15 US US09/868,535 patent/US7148214B1/en not_active Expired - Lifetime
- 1999-12-15 CA CA2355939A patent/CA2355939C/en not_active Expired - Lifetime
- 1999-12-15 IL IL14376799A patent/IL143767A0/xx not_active IP Right Cessation
- 1999-12-15 EE EEP200100328A patent/EE04917B1/xx unknown
- 1999-12-15 AT AT99964625T patent/ATE294178T1/de active
- 1999-12-15 SI SI9930798T patent/SI1144411T1/xx unknown
- 1999-12-15 ES ES99964625T patent/ES2242443T3/es not_active Expired - Lifetime
- 1999-12-15 EP EP99964625A patent/EP1144411B1/en not_active Expired - Lifetime
- 1999-12-15 CZ CZ20012069A patent/CZ301953B6/cs not_active IP Right Cessation
- 1999-12-15 DE DE69925036T patent/DE69925036T2/de not_active Expired - Lifetime
- 1999-12-15 NZ NZ512870A patent/NZ512870A/en not_active IP Right Cessation
- 1999-12-15 PL PL348295A patent/PL196262B1/pl unknown
- 1999-12-15 SK SK814-2001A patent/SK286158B6/sk not_active IP Right Cessation
- 1999-12-15 PT PT99964625T patent/PT1144411E/pt unknown
- 1999-12-15 UA UA2001064351A patent/UA74537C2/uk unknown
- 1999-12-15 JP JP2000589540A patent/JP4601175B2/ja not_active Expired - Lifetime
- 1999-12-15 EA EA200100681A patent/EA004500B1/ru not_active IP Right Cessation
- 1999-12-17 MY MYPI99005537A patent/MY129663A/en unknown
- 1999-12-17 TW TW088122194A patent/TWI250981B/zh not_active IP Right Cessation
- 1999-12-17 AR ARP990106513A patent/AR021888A1/es active IP Right Grant
- 1999-12-17 CO CO99079021A patent/CO5140116A1/es unknown
- 1999-12-18 EG EG162699A patent/EG24605A/xx active
-
2000
- 2000-05-21 SA SA00210113A patent/SA00210113B1/ar unknown
-
2001
- 2001-05-29 BG BG105546A patent/BG65133B1/bg unknown
- 2001-06-01 NO NO20012710A patent/NO318891B1/no not_active IP Right Cessation
- 2001-06-15 HR HR20010453A patent/HRP20010453B1/xx not_active IP Right Cessation
- 2001-06-18 ZA ZA200104977A patent/ZA200104977B/en unknown
-
2002
- 2002-07-03 HK HK02104999.1A patent/HK1043128B/zh unknown
-
2004
- 2004-07-26 US US10/898,844 patent/US7087595B2/en not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK4A | Patent expired |
Expiry date: 20191215 |