SK286064B6 - Fenylpiperazínové deriváty, spôsob ich prípravy afarmaceutické kompozície, ktoré ich obsahujú - Google Patents

Fenylpiperazínové deriváty, spôsob ich prípravy afarmaceutické kompozície, ktoré ich obsahujú Download PDF

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Publication number
SK286064B6
SK286064B6 SK1805-2002A SK18052002A SK286064B6 SK 286064 B6 SK286064 B6 SK 286064B6 SK 18052002 A SK18052002 A SK 18052002A SK 286064 B6 SK286064 B6 SK 286064B6
Authority
SK
Slovakia
Prior art keywords
general formula
compound
preparation
phenylpiperazine
formula
Prior art date
Application number
SK1805-2002A
Other languages
English (en)
Slovak (sk)
Other versions
SK18052002A3 (sk
Inventor
Roelof W. Feenstra
Eric Ronken
Cornelis G. Kruse
Andrew C. Mccreary
Scharrenburg Gustaaf J. M. Van
Original Assignee
Solvay Pharmaceuticals B. V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharmaceuticals B. V. filed Critical Solvay Pharmaceuticals B. V.
Publication of SK18052002A3 publication Critical patent/SK18052002A3/sk
Publication of SK286064B6 publication Critical patent/SK286064B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06Peri-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SK1805-2002A 2001-02-21 2002-02-19 Fenylpiperazínové deriváty, spôsob ich prípravy afarmaceutické kompozície, ktoré ich obsahujú SK286064B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01200609 2001-02-21
PCT/EP2002/001793 WO2002066472A1 (en) 2001-02-21 2002-02-19 New phenylpiperazines

Publications (2)

Publication Number Publication Date
SK18052002A3 SK18052002A3 (sk) 2003-05-02
SK286064B6 true SK286064B6 (sk) 2008-02-05

Family

ID=8179908

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1805-2002A SK286064B6 (sk) 2001-02-21 2002-02-19 Fenylpiperazínové deriváty, spôsob ich prípravy afarmaceutické kompozície, ktoré ich obsahujú

Country Status (29)

Country Link
US (1) US6828325B2 (es)
EP (1) EP1395583B1 (es)
JP (1) JP4178033B2 (es)
KR (1) KR100848482B1 (es)
CN (1) CN1190433C (es)
AR (1) AR032711A1 (es)
AT (1) ATE289604T1 (es)
AU (1) AU2002253043B2 (es)
BR (1) BR0205220A (es)
CA (1) CA2411973A1 (es)
CZ (1) CZ299487B6 (es)
DE (1) DE60203042T2 (es)
DK (1) DK1395583T3 (es)
DZ (1) DZ3441A1 (es)
ES (1) ES2235029T3 (es)
HK (1) HK1059781A1 (es)
HU (1) HUP0303329A3 (es)
IL (1) IL153176A (es)
MX (1) MXPA03004242A (es)
NO (1) NO323781B1 (es)
NZ (1) NZ523135A (es)
PL (1) PL359650A1 (es)
PT (1) PT1395583E (es)
RU (1) RU2279431C2 (es)
SI (1) SI1395583T1 (es)
SK (1) SK286064B6 (es)
UA (1) UA74426C2 (es)
WO (1) WO2002066472A1 (es)
ZA (1) ZA200209897B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1212320T1 (en) * 1999-08-23 2005-10-31 Solvay Pharmaceuticals B.V. Phenylpiperazines as serotonin reuptake inhibitors
AR032712A1 (es) 2001-02-21 2003-11-19 Solvay Pharm Bv Un mesilato de derivados de fenilpiperazina y composiciones farmaceuticas que lo contienen
JP5080716B2 (ja) 2001-07-20 2012-11-21 サイコジェニックス・インコーポレーテッド 注意欠陥・多動性障害の治療
EP1683790A1 (en) * 2005-01-24 2006-07-26 Institut National De La Sante Et De La Recherche Medicale (Inserm) 3,4-dihydro-2-naphthamide derivatives as selective dopamine D3 ligands
GB0708818D0 (en) * 2007-05-08 2007-06-13 Portela & Ca Sa Compounds
WO2011082266A2 (en) 2009-12-30 2011-07-07 Arqule, Inc. Substituted heterocyclic compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0900792B1 (en) * 1997-09-02 2003-10-29 Duphar International Research B.V Piperazine and piperidine derivatives as 5-HT1A and dopamine D2-receptor (ant)agonists
NZ508506A (en) * 1998-06-19 2004-01-30 H 4,5,6 and 7-indole and indoline derivatives, their preparation and use
AR020773A1 (es) * 1998-10-16 2002-05-29 Duphar Int Res Compuesto derivados de 3-(tetrahidropiridin-4-il)indol, metodo para prepararlo, una composicion farmaceutica que los contiene, metodo para preparar dicha composicion y uso del compuesto
SI1212320T1 (en) 1999-08-23 2005-10-31 Solvay Pharmaceuticals B.V. Phenylpiperazines as serotonin reuptake inhibitors
EP1336406A1 (en) 2002-02-14 2003-08-20 Solvay Pharmaceuticals B.V. Partial dopamine-D2 receptor agonist plus serotonin and/or noradrenaline inhibitory activity

Also Published As

Publication number Publication date
ATE289604T1 (de) 2005-03-15
NO323781B1 (no) 2007-07-02
HUP0303329A2 (hu) 2004-01-28
EP1395583B1 (en) 2005-02-23
KR100848482B1 (ko) 2008-07-28
CN1190433C (zh) 2005-02-23
US20030162791A1 (en) 2003-08-28
KR20030072215A (ko) 2003-09-13
CZ299487B6 (cs) 2008-08-13
HK1059781A1 (en) 2004-07-16
DE60203042D1 (de) 2005-03-31
ZA200209897B (en) 2004-03-05
US6828325B2 (en) 2004-12-07
NZ523135A (en) 2005-02-25
SK18052002A3 (sk) 2003-05-02
PL359650A1 (en) 2004-08-23
MXPA03004242A (es) 2003-09-22
AU2002253043B2 (en) 2006-06-08
RU2279431C2 (ru) 2006-07-10
EP1395583A1 (en) 2004-03-10
HUP0303329A3 (en) 2008-12-29
ES2235029T3 (es) 2005-07-01
UA74426C2 (uk) 2005-12-15
IL153176A (en) 2012-10-31
BR0205220A (pt) 2003-06-24
WO2002066472A1 (en) 2002-08-29
NO20025902L (no) 2002-12-09
JP4178033B2 (ja) 2008-11-12
CZ20023933A3 (cs) 2003-03-12
DE60203042T2 (de) 2006-01-19
NO20025902D0 (no) 2002-12-09
JP2004518746A (ja) 2004-06-24
CN1463269A (zh) 2003-12-24
DZ3441A1 (fr) 2002-08-29
CA2411973A1 (en) 2002-08-29
DK1395583T3 (da) 2005-03-29
PT1395583E (pt) 2005-06-30
SI1395583T1 (es) 2005-08-31
AR032711A1 (es) 2003-11-19
IL153176A0 (en) 2003-06-24

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20120219