SK285133B6 - Dolastatin-15 deriváty v kombinácii s taxanmi a ich použitie - Google Patents

Dolastatin-15 deriváty v kombinácii s taxanmi a ich použitie Download PDF

Info

Publication number
SK285133B6
SK285133B6 SK1251-99A SK125199A SK285133B6 SK 285133 B6 SK285133 B6 SK 285133B6 SK 125199 A SK125199 A SK 125199A SK 285133 B6 SK285133 B6 SK 285133B6
Authority
SK
Slovakia
Prior art keywords
compound
formula
pro
tert
carbonyl
Prior art date
Application number
SK1251-99A
Other languages
English (en)
Slovak (sk)
Other versions
SK125199A3 (en
Inventor
Teresa Barlozzari
Andreas Haupt
Original Assignee
Abbott Gmbh & Co. Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Gmbh & Co. Kg filed Critical Abbott Gmbh & Co. Kg
Publication of SK125199A3 publication Critical patent/SK125199A3/sk
Publication of SK285133B6 publication Critical patent/SK285133B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SK1251-99A 1997-03-13 1998-03-09 Dolastatin-15 deriváty v kombinácii s taxanmi a ich použitie SK285133B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/819,101 US6103698A (en) 1997-03-13 1997-03-13 Dolastatin-15 derivatives in combination with taxanes
PCT/US1998/004594 WO1998040092A1 (fr) 1997-03-13 1998-03-09 Derives de dolastatine-15 en association avec des taxanes

Publications (2)

Publication Number Publication Date
SK125199A3 SK125199A3 (en) 2000-08-14
SK285133B6 true SK285133B6 (sk) 2006-07-07

Family

ID=25227196

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1251-99A SK285133B6 (sk) 1997-03-13 1998-03-09 Dolastatin-15 deriváty v kombinácii s taxanmi a ich použitie

Country Status (30)

Country Link
US (2) US6103698A (fr)
EP (1) EP0981358B1 (fr)
JP (1) JP2001514659A (fr)
KR (1) KR100555604B1 (fr)
CN (1) CN1157223C (fr)
AT (1) ATE241376T1 (fr)
AU (1) AU728027B2 (fr)
BG (1) BG64338B1 (fr)
BR (1) BR9808249A (fr)
CA (1) CA2282720C (fr)
CO (1) CO4940498A1 (fr)
CZ (1) CZ293905B6 (fr)
DE (1) DE69815100T2 (fr)
DK (1) DK0981358T3 (fr)
ES (1) ES2200317T3 (fr)
HK (1) HK1026851A1 (fr)
HR (1) HRP980125A2 (fr)
HU (1) HU228860B1 (fr)
ID (1) ID23900A (fr)
IL (2) IL131597A0 (fr)
NO (1) NO323894B1 (fr)
NZ (1) NZ337416A (fr)
PL (1) PL197834B1 (fr)
PT (1) PT981358E (fr)
RU (1) RU2218174C2 (fr)
SK (1) SK285133B6 (fr)
TR (1) TR199902244T2 (fr)
TW (1) TWI277426B (fr)
WO (1) WO1998040092A1 (fr)
ZA (1) ZA982093B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010009901A1 (en) * 1996-12-11 2001-07-26 Basf Aktiengesellschaft Germany Antineoplastic peptides
WO2001024763A2 (fr) 1999-10-01 2001-04-12 Immunogen, Inc. Compositions et methodes de traitement du cancer utilisant des immunoconjugues et des agents chimiotherapeutiques
US20040101511A1 (en) * 2000-11-08 2004-05-27 Young Aiping H Combination preparation of a biological response modifier and an anticancer agent and uses thereof
US20050192443A1 (en) * 2000-11-08 2005-09-01 Lorus Therapeutics Inc. Biological response modifier for the treatment of cancer
JP4954983B2 (ja) 2005-05-18 2012-06-20 ファーマサイエンス・インコーポレイテッド Ｂｉｒドメイン結合化合物
WO2007131366A1 (fr) 2006-05-16 2007-11-22 Aegera Therapeutics Inc. Composés de liaison au domaine iap bir
CN102933231B (zh) 2010-02-10 2015-07-29 伊缪诺金公司 Cd20抗体及其用途
AU2011214057B2 (en) 2010-02-12 2016-11-17 Pharmascience Inc. IAP BIR domain binding compounds
JPWO2021246471A1 (fr) * 2020-06-03 2021-12-09
WO2023033129A1 (fr) 2021-09-03 2023-03-09 東レ株式会社 Composition pharmaceutique pour le traitement et/ou la prévention du cancer

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816444A (en) * 1987-07-10 1989-03-28 Arizona Board Of Regents, Arizona State University Cell growth inhibitory substance
US5676978A (en) 1989-02-14 1997-10-14 Amira, Inc. Methods of inhibiting undesirable cell growth using a combination of a cyclocreatine compound and a hyperplastic inhibitory agent
US4879278A (en) 1989-05-16 1989-11-07 Arizona Board Of Regents Isolation and structural elucidation of the cytostatic linear depsipeptide dolastatin 15
US5278324A (en) * 1990-08-28 1994-01-11 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
MX9102128A (es) 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
KR0185440B1 (ko) 1991-08-09 1999-04-01 야마구찌 다까시 신규의 테트라 펩티트 유도체
US5250683A (en) * 1991-09-23 1993-10-05 Florida State University Certain substituted taxanes and pharmaceutical compositions containing them
US5227400A (en) * 1991-09-23 1993-07-13 Florida State University Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
US5272171A (en) * 1992-02-13 1993-12-21 Bristol-Myers Squibb Company Phosphonooxy and carbonate derivatives of taxol
FR2688518B1 (fr) * 1992-03-13 1994-05-06 Rhone Poulenc Rorer Sa Procede de preparation de derives du taxane.
US5831002A (en) * 1992-05-20 1998-11-03 Basf Aktiengesellschaft Antitumor peptides
US5248796A (en) * 1992-06-18 1993-09-28 Bristol-Myers Squibb Company Taxol derivatives
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
FR2697752B1 (fr) * 1992-11-10 1995-04-14 Rhone Poulenc Rorer Sa Compositions antitumorales contenant des dérivés du taxane.
NZ258882A (en) * 1992-12-16 1997-06-24 Basf Ag Antineoplastic peptides and compositions thereof
US5484612A (en) * 1993-09-22 1996-01-16 The Board Of Trustees Of The Leland Stanford Junior University Method of treating a mammal having a solid tumor susceptible to treatment with cisplatin
CA2129282A1 (fr) 1993-09-29 1995-03-30 George Weber Methode de traitement des maladies neoplasiques a l'aide du taxol et du triazofurin
US5447936A (en) * 1993-12-22 1995-09-05 Bionumerik Pharmaceuticals, Inc. Lactone stable formulation of 10-hydroxy 7-ethyl camptothecin and methods for uses thereof
US5565478A (en) * 1994-03-14 1996-10-15 The United States Of America As Represented By The Department Of Health & Human Services Combination therapy using signal transduction inhibitors with paclitaxel and other taxane analogs
US5494930A (en) * 1994-06-02 1996-02-27 Shimizu; Yuzuru Caribenolide I
US5525613A (en) * 1994-06-16 1996-06-11 Entropin, Inc. Covalently coupled benzoylecgonine ecgonine and ecgonidine
US5530097A (en) * 1994-08-01 1996-06-25 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory peptide amides
US5504191A (en) * 1994-08-01 1996-04-02 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory pentapeptide methyl esters
US5543423A (en) * 1994-11-16 1996-08-06 Vertex Pharmaceuticals, Incorporated Amino acid derivatives with improved multi-drug resistance activity
JPH10510812A (ja) 1994-12-15 1998-10-20 ベーカー ノートン ファーマスーティカルズ、インコーポレーテッド タクサン化合物およびテルルおよび／またはセレン化合物の併用により腫瘍の発育を減少させるための方法および組成物

Also Published As

Publication number Publication date
PL197834B1 (pl) 2008-04-30
CA2282720C (fr) 2009-12-29
CZ321199A3 (cs) 2000-02-16
HUP0001381A2 (hu) 2000-10-28
EP0981358B1 (fr) 2003-05-28
HUP0001381A3 (en) 2001-12-28
CZ293905B6 (cs) 2004-08-18
RU2218174C2 (ru) 2003-12-10
PL335579A1 (en) 2000-05-08
DK0981358T3 (da) 2003-09-22
CA2282720A1 (fr) 1998-09-17
IL131597A0 (en) 2001-01-28
ATE241376T1 (de) 2003-06-15
DE69815100D1 (de) 2003-07-03
IL131597A (en) 2006-06-11
CN1157223C (zh) 2004-07-14
CN1252728A (zh) 2000-05-10
ES2200317T3 (es) 2004-03-01
WO1998040092A1 (fr) 1998-09-17
NZ337416A (en) 2001-05-25
KR20000076211A (ko) 2000-12-26
US6632795B1 (en) 2003-10-14
ID23900A (id) 2000-05-25
JP2001514659A (ja) 2001-09-11
TR199902244T2 (xx) 1999-12-21
CO4940498A1 (es) 2000-07-24
EP0981358A1 (fr) 2000-03-01
ZA982093B (en) 1999-09-12
DE69815100T2 (de) 2004-02-05
KR100555604B1 (ko) 2006-03-03
SK125199A3 (en) 2000-08-14
HRP980125A2 (en) 1999-02-28
BG64338B1 (bg) 2004-10-29
US6103698A (en) 2000-08-15
AU6694598A (en) 1998-09-29
BG103728A (en) 2000-04-28
PT981358E (pt) 2003-09-30
AU728027B2 (en) 2001-01-04
TWI277426B (en) 2007-04-01
HU228860B1 (en) 2013-06-28
NO994408L (no) 1999-11-10
NO323894B1 (no) 2007-07-16
NO994408D0 (no) 1999-09-10
HK1026851A1 (en) 2000-12-29
BR9808249A (pt) 2000-05-16

Similar Documents

Publication Publication Date Title
CZ286752B6 (en) Peptide and pharmaceutical preparation containing thereof
PL185763B1 (pl) Nowe peptydy stanowiące pochodne dolastatyny, ichzastosowanie w medycynie oraz kompozycja farmaceutyczna
IL105651A (en) History of dolastatin preparation and pharmaceutical preparations containing them
SK285133B6 (sk) Dolastatin-15 deriváty v kombinácii s taxanmi a ich použitie
EP1021200B1 (fr) Methodes et compositions de traitement de la polyarthrite rhumatoide
IL166853A (en) Antineoplastic peptides, their preparation and various uses thereof
US20010009901A1 (en) Antineoplastic peptides
AU775090B2 (en) Antineoplastic peptides
MXPA99008066A (en) Dolastatin-15 derivatives in combination with taxanes
CZ20001211A3 (cs) Prostředky pro léčení revmatoidní artritidy

Legal Events

Date Code Title Description
PC4A Assignment and transfer of rights

Owner name: ABBVIE DEUTSCHLAND GMBH & CO. KG, WIESBADEN, DE

Free format text: FORMER OWNER: ABBOTT GMBH & CO. KG, WIESBADEN, DE

Effective date: 20141020

MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20150309