SK283378B6 - Farmaceuticky aktívne tricyklické amíny, medziprodukty na ich prípravu - Google Patents

Farmaceuticky aktívne tricyklické amíny, medziprodukty na ich prípravu Download PDF

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Publication number
SK283378B6
SK283378B6 SK901-99A SK90199A SK283378B6 SK 283378 B6 SK283378 B6 SK 283378B6 SK 90199 A SK90199 A SK 90199A SK 283378 B6 SK283378 B6 SK 283378B6
Authority
SK
Slovakia
Prior art keywords
pyrrolidinyl
pyrimido
indol
acetic acid
formula
Prior art date
Application number
SK901-99A
Other languages
English (en)
Slovak (sk)
Other versions
SK90199A3 (en
Inventor
Gordon L. Bundy
Original Assignee
Pharmacia & Upjohn Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Company filed Critical Pharmacia & Upjohn Company
Publication of SK90199A3 publication Critical patent/SK90199A3/sk
Publication of SK283378B6 publication Critical patent/SK283378B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/12—Mucolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Cosmetics (AREA)
SK901-99A 1997-01-08 1997-12-19 Farmaceuticky aktívne tricyklické amíny, medziprodukty na ich prípravu SK283378B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3522397P 1997-01-08 1997-01-08
US4374997P 1997-04-09 1997-04-09
PCT/US1997/024300 WO1998042708A2 (en) 1997-01-08 1997-12-19 Pharmaceutically active tricyclic amines

Publications (2)

Publication Number Publication Date
SK90199A3 SK90199A3 (en) 2000-05-16
SK283378B6 true SK283378B6 (sk) 2003-06-03

Family

ID=26711898

Family Applications (1)

Application Number Title Priority Date Filing Date
SK901-99A SK283378B6 (sk) 1997-01-08 1997-12-19 Farmaceuticky aktívne tricyklické amíny, medziprodukty na ich prípravu

Country Status (23)

Country Link
US (1) US5932728A (xx)
EP (1) EP0964865B1 (xx)
JP (1) JP2002511061A (xx)
KR (1) KR20000069940A (xx)
CN (1) CN1128798C (xx)
AT (1) ATE233763T1 (xx)
AU (1) AU723709B2 (xx)
CA (1) CA2275389A1 (xx)
CZ (1) CZ288076B6 (xx)
DE (1) DE69719563T2 (xx)
DK (1) DK0964865T3 (xx)
ES (1) ES2193424T3 (xx)
FI (1) FI991568A (xx)
HK (1) HK1023344A1 (xx)
HU (1) HUP0003692A3 (xx)
NO (1) NO312463B1 (xx)
NZ (1) NZ336659A (xx)
PL (1) PL334451A1 (xx)
PT (1) PT964865E (xx)
RU (1) RU2200737C2 (xx)
SI (1) SI0964865T1 (xx)
SK (1) SK283378B6 (xx)
WO (1) WO1998042708A2 (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7345051B2 (en) 2000-01-31 2008-03-18 Genaera Corporation Mucin synthesis inhibitors
US20020147216A1 (en) * 2000-01-31 2002-10-10 Yuhong Zhou Mucin synthesis inhibitors
JP2004507444A (ja) * 2000-01-31 2004-03-11 ジェネーラ　コーポレーション ムチン合成インヒビター
JP2005515173A (ja) * 2001-10-31 2005-05-26 バイエル・ヘルスケア・アクチェンゲゼルシャフト ピリミド［４，５−ｂ］インドール誘導体
WO2004058764A1 (en) * 2002-12-27 2004-07-15 Bayer Healthcare Ag 4-phenyl-pyrimido [4,5-b] indole derivatives
WO2011011186A2 (en) * 2009-07-22 2011-01-27 The Board Of Trustees Of The University Of Illinois Hdac inhibitors and therapeutic methods using the same
EP2686320B1 (en) 2011-03-15 2016-05-18 Merck Sharp & Dohme Corp. Tricyclic gyrase inhibitors
DK2807165T3 (da) * 2012-01-27 2019-07-15 Univ Montreal Pyrimido[4,5-b]indol-derivater og anvendelse deraf i ekspansionen af hæmatopoietiske stamceller
AU2016273439B2 (en) 2015-06-05 2020-11-05 Héma-Québec Methods for culturing and/or differentiating hematopoietic stem cells into progenitors and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5502187A (en) * 1992-04-03 1996-03-26 The Upjohn Company Pharmaceutically active bicyclic-heterocyclic amines
JPH08502721A (ja) * 1992-04-03 1996-03-26 ジ・アップジョン・カンパニー 医薬的に活性な二環式‐複素環アミン
KR19980702716A (ko) * 1995-03-02 1998-08-05 웰츠로렌스티 피리미도[4,5-비]인돌

Also Published As

Publication number Publication date
HK1023344A1 (en) 2000-09-08
CA2275389A1 (en) 1998-10-01
HUP0003692A2 (hu) 2001-04-28
RU2200737C2 (ru) 2003-03-20
PL334451A1 (en) 2000-02-28
CZ238899A3 (cs) 1999-10-13
US5932728A (en) 1999-08-03
NZ336659A (en) 2001-01-26
DE69719563T2 (de) 2003-11-27
AU723709B2 (en) 2000-09-07
NO993359L (no) 1999-09-07
PT964865E (pt) 2003-06-30
CN1128798C (zh) 2003-11-26
SK90199A3 (en) 2000-05-16
HUP0003692A3 (en) 2002-10-28
CN1239961A (zh) 1999-12-29
DK0964865T3 (da) 2003-05-05
EP0964865A2 (en) 1999-12-22
AU8655498A (en) 1998-10-20
DE69719563D1 (de) 2003-04-10
ATE233763T1 (de) 2003-03-15
FI991568A (fi) 1999-07-08
KR20000069940A (ko) 2000-11-25
WO1998042708A2 (en) 1998-10-01
CZ288076B6 (cs) 2001-04-11
SI0964865T1 (en) 2003-08-31
JP2002511061A (ja) 2002-04-09
NO312463B1 (no) 2002-05-13
WO1998042708A3 (en) 1998-12-17
ES2193424T3 (es) 2003-11-01
EP0964865B1 (en) 2003-03-05
NO993359D0 (no) 1999-07-07

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