SK281302B6 - Amidové deriváty vitamínu d, spôsob ich výroby, ich použitie a farmaceutické kompozície s ich obsahom - Google Patents

Amidové deriváty vitamínu d, spôsob ich výroby, ich použitie a farmaceutické kompozície s ich obsahom Download PDF

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Publication number
SK281302B6
SK281302B6 SK522-94A SK52294A SK281302B6 SK 281302 B6 SK281302 B6 SK 281302B6 SK 52294 A SK52294 A SK 52294A SK 281302 B6 SK281302 B6 SK 281302B6
Authority
SK
Slovakia
Prior art keywords
group
formula
dihydroxy
compound
compounds
Prior art date
Application number
SK522-94A
Other languages
English (en)
Slovak (sk)
Other versions
SK52294A3 (en
Inventor
Robert Henry Hesse
Gaddam Subba Reddy
Sundara Katugam Srinivasasetty Setty
Original Assignee
Research Institute For Medicine And Chemistry
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919123712A external-priority patent/GB9123712D0/en
Priority claimed from GB929209658A external-priority patent/GB9209658D0/en
Application filed by Research Institute For Medicine And Chemistry filed Critical Research Institute For Medicine And Chemistry
Publication of SK52294A3 publication Critical patent/SK52294A3/sk
Publication of SK281302B6 publication Critical patent/SK281302B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
SK522-94A 1991-11-07 1992-11-06 Amidové deriváty vitamínu d, spôsob ich výroby, ich použitie a farmaceutické kompozície s ich obsahom SK281302B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919123712A GB9123712D0 (en) 1991-11-07 1991-11-07 Chemical compounds
GB929209658A GB9209658D0 (en) 1992-05-05 1992-05-05 Chemical compounds
PCT/EP1992/002577 WO1993009093A1 (en) 1991-11-07 1992-11-06 Vitamin d amide derivatives

Publications (2)

Publication Number Publication Date
SK52294A3 SK52294A3 (en) 1994-11-09
SK281302B6 true SK281302B6 (sk) 2001-02-12

Family

ID=26299825

Family Applications (1)

Application Number Title Priority Date Filing Date
SK522-94A SK281302B6 (sk) 1991-11-07 1992-11-06 Amidové deriváty vitamínu d, spôsob ich výroby, ich použitie a farmaceutické kompozície s ich obsahom

Country Status (20)

Country Link
US (2) US5494905A (da)
EP (1) EP0614455B1 (da)
JP (1) JP3282811B2 (da)
KR (1) KR100271461B1 (da)
AT (1) ATE134366T1 (da)
AU (1) AU664213B2 (da)
CA (1) CA2121678C (da)
CZ (1) CZ288031B6 (da)
DE (1) DE69208478T2 (da)
DK (1) DK0614455T3 (da)
ES (1) ES2083771T3 (da)
FI (1) FI106119B (da)
GR (1) GR3019601T3 (da)
HU (1) HU221008B1 (da)
NO (1) NO305315B1 (da)
NZ (1) NZ245041A (da)
PL (1) PL171580B1 (da)
RU (1) RU2139276C1 (da)
SK (1) SK281302B6 (da)
WO (1) WO1993009093A1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU221008B1 (hu) * 1991-11-07 2002-07-29 Research Institute For Medicine And Chemistry D-vitamin-származékok és azokat tartalmazó gyógyászati készítmények
IL107185A (en) * 1992-10-06 1998-02-22 Schering Ag History of 52-carboxylic acid, processes for their preparation and pharmaceutical preparations containing them
WO2004076688A1 (ja) * 1993-02-12 2004-09-10 Etsuro Ogata 無症候腎障害のモニタリング法
GB9309422D0 (en) * 1993-05-07 1993-06-23 Res Inst Medicine Chem Chemical compounds
GB9325415D0 (en) * 1993-12-13 1994-02-16 Res Inst Medicine Chem Chemical compounds
GB9405715D0 (en) * 1994-03-23 1994-05-11 Res Inst Medicine Chem Chemical compounds
US5661141A (en) * 1995-03-27 1997-08-26 Petrow; Vladimir 19-oxygenated steroids as therapeutic agents
US5678570A (en) * 1995-04-14 1997-10-21 The University Of North Carolina At Chapel Hill Method of treating cardiac arrest
US5696103A (en) * 1995-11-17 1997-12-09 Syntex (U.S.A.) Inc. Method for treating osteoporosis
DE19619036A1 (de) * 1996-04-30 1997-11-13 Schering Ag Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US6043385A (en) * 1997-12-16 2000-03-28 Hoffman-La Roche Inc. Vitamin D derivatives
GB9804861D0 (en) * 1998-03-06 1998-04-29 Res Inst Medicine Chem Chemical compounds
WO2000024712A1 (fr) * 1998-10-23 2000-05-04 Teijin Limited Derives de vitamine d3 et medicaments contre des maladies respiratoires inflammatoires les contenant
DE19935771A1 (de) * 1999-07-23 2001-02-01 Schering Ag Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US6703380B2 (en) 1999-09-29 2004-03-09 Colotech A/S Prevention of cancer
DE60019947T2 (de) 1999-09-29 2006-02-02 Colotech A/S Prävention von kolorektalem Krebs
WO2001030751A2 (en) * 1999-10-25 2001-05-03 Strakan Limited USES OF 1,25-DIHYDROXY-5,6-trans VITAMIN D COMPOUNDS AND DERIVATIVES THEREOF
TWI288131B (en) * 2000-06-15 2007-10-11 Chugai Pharmaceutical Co Ltd Vitamin D derivative, compounds pharmaceutical composition thereof
EP1812011A1 (en) 2004-11-12 2007-08-01 Bioxell S.p.a. Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
US20100016435A1 (en) * 2006-05-16 2010-01-21 Mcgill University Hybrid molecules having mixed vitamin d receptor agonism and histone deacetylase inhibitory properties
WO2009117831A1 (en) * 2008-03-27 2009-10-01 The Royal Institution For The Advancement Of Learning/Mcgill University Hybrid molecules having mixed vitamin d receptor agonism and histone deacetylase inhibitory properties
WO2012158794A1 (en) 2011-05-17 2012-11-22 Wisconsin Alumni Research Foundation N-cyclopropyl-(20r)-2-methylene-19,26,27-trinor-25-aza-vitamin d analogs and their uses
EP4215519A4 (en) * 2020-09-15 2024-03-06 Teijin Pharma Limited VITAMIN D DERIVATIVE WITH CYCLIC AMINE IN THE SIDE CHAIN

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4217288A (en) * 1977-03-24 1980-08-12 Wisconsin Alumni Research Foundation Anti-vitamin D compounds
FR2426044A2 (fr) * 1978-05-19 1979-12-14 Wisconsin Research Foundation Derives de la vitamine d3 ayant une activite anti-vitamine d
US5206230A (en) * 1991-06-05 1993-04-27 Daikin Industries, Ltd. Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same
HU221008B1 (hu) * 1991-11-07 2002-07-29 Research Institute For Medicine And Chemistry D-vitamin-származékok és azokat tartalmazó gyógyászati készítmények

Also Published As

Publication number Publication date
AU2901492A (en) 1993-06-07
FI942114A (fi) 1994-05-06
CA2121678A1 (en) 1993-05-13
CA2121678C (en) 2005-03-15
NO305315B1 (no) 1999-05-10
FI106119B (fi) 2000-11-30
EP0614455B1 (en) 1996-02-21
WO1993009093A1 (en) 1993-05-13
RU2139276C1 (ru) 1999-10-10
JP3282811B2 (ja) 2002-05-20
HU9401372D0 (en) 1994-08-29
DE69208478T2 (de) 1996-09-05
NZ245041A (en) 1995-03-28
US5494905A (en) 1996-02-27
HUT67140A (en) 1995-02-28
EP0614455A1 (en) 1994-09-14
PL171580B1 (pl) 1997-05-30
JPH07502499A (ja) 1995-03-16
HU221008B1 (hu) 2002-07-29
CZ111294A3 (en) 1995-03-15
KR100271461B1 (ko) 2000-11-15
NO941683L (da) 1994-06-27
ES2083771T3 (es) 1996-04-16
SK52294A3 (en) 1994-11-09
US5686435A (en) 1997-11-11
FI942114A0 (fi) 1994-05-06
CZ288031B6 (cs) 2001-04-11
GR3019601T3 (en) 1996-07-31
DE69208478D1 (de) 1996-03-28
NO941683D0 (no) 1994-05-06
DK0614455T3 (da) 1996-03-18
ATE134366T1 (de) 1996-03-15
AU664213B2 (en) 1995-11-09

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