SK280840B6 - Lyofilizovaný prípravok obsahujúci 1,1',1''-fosfinotioylidíntrisaziridín a spôsob jeho výroby - Google Patents

Lyofilizovaný prípravok obsahujúci 1,1',1''-fosfinotioylidíntrisaziridín a spôsob jeho výroby Download PDF

Info

Publication number
SK280840B6
SK280840B6 SK1352-94A SK135294A SK280840B6 SK 280840 B6 SK280840 B6 SK 280840B6 SK 135294 A SK135294 A SK 135294A SK 280840 B6 SK280840 B6 SK 280840B6
Authority
SK
Slovakia
Prior art keywords
thiotepa
pharmaceutically acceptable
lyophilized
aqueous solution
acceptable base
Prior art date
Application number
SK1352-94A
Other languages
English (en)
Slovak (sk)
Other versions
SK135294A3 (en
Inventor
Mannching S. Ku
Jorge Velez
Joe Hoffman
Lourdes Zamora
Original Assignee
American Cyanamid Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Company filed Critical American Cyanamid Company
Publication of SK135294A3 publication Critical patent/SK135294A3/sk
Publication of SK280840B6 publication Critical patent/SK280840B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK1352-94A 1993-11-09 1994-11-09 Lyofilizovaný prípravok obsahujúci 1,1',1''-fosfinotioylidíntrisaziridín a spôsob jeho výroby SK280840B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15050193A 1993-11-09 1993-11-09

Publications (2)

Publication Number Publication Date
SK135294A3 SK135294A3 (en) 1996-01-10
SK280840B6 true SK280840B6 (sk) 2000-08-14

Family

ID=22534834

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1352-94A SK280840B6 (sk) 1993-11-09 1994-11-09 Lyofilizovaný prípravok obsahujúci 1,1',1''-fosfinotioylidíntrisaziridín a spôsob jeho výroby

Country Status (29)

Country Link
US (1) US5561121A (fi)
EP (1) EP0656211B1 (fi)
JP (1) JP3726255B2 (fi)
KR (1) KR100348382B1 (fi)
CN (1) CN1111130A (fi)
AR (1) AR023045A2 (fi)
AT (1) ATE180670T1 (fi)
AU (1) AU690143B2 (fi)
CA (1) CA2135265A1 (fi)
CZ (1) CZ287052B6 (fi)
DE (1) DE69418832T2 (fi)
DK (1) DK0656211T3 (fi)
ES (1) ES2133152T3 (fi)
FI (1) FI116036B (fi)
GR (1) GR3031122T3 (fi)
HK (1) HK1011283A1 (fi)
HU (1) HU218216B (fi)
IL (1) IL111534A (fi)
NO (1) NO305274B1 (fi)
NZ (1) NZ264861A (fi)
PE (1) PE22995A1 (fi)
PH (1) PH31219A (fi)
PL (1) PL176984B1 (fi)
RU (1) RU2134112C1 (fi)
SG (1) SG63584A1 (fi)
SI (1) SI0656211T1 (fi)
SK (1) SK280840B6 (fi)
TW (1) TW344662B (fi)
ZA (1) ZA948833B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9726343D0 (en) * 1997-12-13 1998-02-11 Auffret Anthony The use of excipients to accelerate freeze-drying
EP1399131A2 (en) * 2001-06-08 2004-03-24 Powderject Vaccines, Inc. Spray freeze-dried compositions
US8436190B2 (en) 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
US8158152B2 (en) * 2005-11-18 2012-04-17 Scidose Llc Lyophilization process and products obtained thereby
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
CA2735899A1 (en) 2008-09-25 2010-04-01 Cephalon, Inc. Liquid formulations of bendamustine
UA109109C2 (uk) 2009-01-15 2015-07-27 Сефалон, Інк. Кристалічна форма вільної основи бендамустину (варіанти) та фармацевтична композиція для лікування раку (варіанти)
JP2014528953A (ja) * 2011-09-29 2014-10-30 ヤンセン ファーマシューティカ エヌ．ベー． スルファミド誘導体の調製プロセス
CN104349417B (zh) * 2013-08-07 2017-11-21 中国科学院声学研究所 基于短生命周期的区域性水下通信网的组网方法
WO2018227112A1 (en) 2017-06-09 2018-12-13 The Trustees Of Columbia University In The City Of New York Short tat oligomers for drug delivery
CN109956972A (zh) * 2017-12-22 2019-07-02 四川科瑞德凯华制药有限公司 塞替派晶型i及其制备方法和用途
CN110917146A (zh) * 2019-12-03 2020-03-27 黑龙江福和制药集团股份有限公司 一种塞替派粉针及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2670347A (en) * 1952-01-08 1954-02-23 American Cyanamid Co Thiophosphoric acid derivatives and method of preparing the same
GB845823A (en) * 1957-09-19 1960-08-24 Sumitomo Chemical Co Stabilised compositions comprising therapeutic imine derivatives and the preparation thereof
DE1951822C3 (de) * 1969-10-14 1980-12-11 Kowa Co., Ltd., Nagoya, Aichi (Japan) Pharmazeutisches Präparat zur Krebsbehandlung
DE2925009A1 (de) * 1979-06-21 1981-01-08 Basf Ag Zubereitung fuer substanzen, verfahren zu deren herstellung und deren verwendung
WO1984001506A1 (en) * 1982-10-13 1984-04-26 Univ Birmingham Pharmaceutical preparations for use in antitumour therapy
DE3484584D1 (de) * 1983-10-14 1991-06-20 Sumitomo Pharma Injektionen mit verzoegerter abgabe.
CH676508A5 (fi) * 1986-10-13 1991-01-31 Anawa Lab Ag
US4918199A (en) * 1988-01-21 1990-04-17 American Cyanamid Company Process for producing thiotepa
US5122367A (en) * 1989-03-31 1992-06-16 Massachusetts Institute Of Technology Polyanhydride bioerodible controlled release implants for administration of stabilized growth hormone
EP0419890A3 (en) * 1989-09-29 1991-05-29 American Cyanamid Company Stable pharmaceutical formulations for antineoplastic compounds having more than one ethyleneimine group, and method

Also Published As

Publication number Publication date
ATE180670T1 (de) 1999-06-15
JPH07196517A (ja) 1995-08-01
HUT70762A (en) 1995-10-30
PL176984B1 (pl) 1999-08-31
FI116036B (fi) 2005-09-15
DK0656211T3 (da) 1999-11-15
NO305274B1 (no) 1999-05-03
FI945252A (fi) 1995-05-10
EP0656211B1 (en) 1999-06-02
EP0656211A1 (en) 1995-06-07
JP3726255B2 (ja) 2005-12-14
PH31219A (en) 1998-05-05
ZA948833B (en) 1995-07-14
SG63584A1 (en) 1999-03-30
GR3031122T3 (en) 1999-12-31
ES2133152T3 (es) 1999-09-01
NZ264861A (en) 1995-10-26
AR023045A2 (es) 2002-09-04
AU7768994A (en) 1995-05-18
DE69418832T2 (de) 1999-09-23
CN1111130A (zh) 1995-11-08
NO944256L (no) 1995-05-10
DE69418832D1 (de) 1999-07-08
CA2135265A1 (en) 1995-05-10
HU218216B (hu) 2000-06-28
PE22995A1 (es) 1995-09-08
PL305752A1 (en) 1995-05-15
US5561121A (en) 1996-10-01
FI945252A0 (fi) 1994-11-08
SI0656211T1 (en) 1999-08-31
RU94040150A (ru) 1996-09-20
HK1011283A1 (en) 1999-07-09
NO944256D0 (no) 1994-11-08
AU690143B2 (en) 1998-04-23
RU2134112C1 (ru) 1999-08-10
IL111534A (en) 1999-06-20
KR100348382B1 (ko) 2002-11-23
TW344662B (en) 1998-11-11
CZ287052B6 (en) 2000-08-16
HU9403210D0 (en) 1995-01-30
SK135294A3 (en) 1996-01-10
CZ271894A3 (en) 1995-07-12
IL111534A0 (en) 1995-01-24

Similar Documents

Publication Publication Date Title
JP3576180B2 (ja) 改良イフォスファミド凍結乾燥組成物
SK280840B6 (sk) Lyofilizovaný prípravok obsahujúci 1,1',1''-fosfinotioylidíntrisaziridín a spôsob jeho výroby
KR20070084150A (ko) 세팔로스포린 유도체를 위한 안정화된 동결건조 제형물
SK183699A3 (en) Pharmaceutical composition comprising a nucleotide analogue and preparation process thereof
FI83476B (fi) Foerfarande foer framstaellning av en beredning av 7 -difluorometyltioacetamido-7 -metoxi-3-/1-(2 -hydroxialkyl)-1h-tetrazol-5-yl/tiometyl-1-detia-1-oxa-3-cefem-4 -karboxisyra.
AU758857B2 (en) Pharmaceutical compositions for freeze drying
CZ299913B6 (cs) Stabilizovaný farmaceutický prostredek na bázi chinupristinu a dalfopristinu a zpusob jeho prípravy
JP4594736B2 (ja) 安定化されたアンスラサイクリン系化合物の凍結乾燥製剤
KR101314500B1 (ko) 안정성이 개선된 옥사세펨 제제 및 그 제조방법
JPS61130223A (ja) 抗菌性凍結乾燥製剤
US20070299139A1 (en) Lyophilisate Comprising N-Diaminomethylene-2-Methyl-4,5-Di(Methylsulfonyl)Benzamide