SK279933B6 - Polypeptid, jeho subsekvencie a ich použitie - Google Patents

Polypeptid, jeho subsekvencie a ich použitie Download PDF

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Publication number
SK279933B6
SK279933B6 SK6352-90A SK635290A SK279933B6 SK 279933 B6 SK279933 B6 SK 279933B6 SK 635290 A SK635290 A SK 635290A SK 279933 B6 SK279933 B6 SK 279933B6
Authority
SK
Slovakia
Prior art keywords
leu
polypeptide
arg
lys
amino acid
Prior art date
Application number
SK6352-90A
Other languages
English (en)
Slovak (sk)
Other versions
SK635290A3 (en
Inventor
Lata Ramanathan
Gail F. Seelig
Paul P. Tratta
Original Assignee
Schering Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corporation filed Critical Schering Corporation
Publication of SK279933B6 publication Critical patent/SK279933B6/sk
Publication of SK635290A3 publication Critical patent/SK635290A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/247—IL-4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5406—IL-4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SK6352-90A 1989-12-20 1990-12-18 Polypeptide, subsequences thereof and their use SK635290A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45357089A 1989-12-20 1989-12-20

Publications (2)

Publication Number Publication Date
SK279933B6 true SK279933B6 (sk) 1999-06-11
SK635290A3 SK635290A3 (en) 1999-06-11

Family

ID=23801108

Family Applications (1)

Application Number Title Priority Date Filing Date
SK6352-90A SK635290A3 (en) 1989-12-20 1990-12-18 Polypeptide, subsequences thereof and their use

Country Status (26)

Country Link
US (1) US6358509B1 (fi)
EP (1) EP0506826B1 (fi)
JP (1) JPH0730116B2 (fi)
KR (1) KR960016862B1 (fi)
AT (1) ATE136906T1 (fi)
AU (1) AU639754B2 (fi)
CA (1) CA2071908C (fi)
CZ (1) CZ283050B6 (fi)
DE (1) DE69026627T2 (fi)
DK (1) DK0506826T3 (fi)
ES (1) ES2085983T3 (fi)
FI (1) FI104180B1 (fi)
GR (1) GR3020325T3 (fi)
HU (1) HU215245B (fi)
IE (1) IE74708B1 (fi)
IL (1) IL96714A0 (fi)
MX (1) MX9203401A (fi)
MY (1) MY106507A (fi)
NO (1) NO922457D0 (fi)
NZ (1) NZ236511A (fi)
OA (1) OA09704A (fi)
PT (1) PT96230B (fi)
SK (1) SK635290A3 (fi)
TW (1) TW221675B (fi)
WO (1) WO1991009059A1 (fi)
ZA (1) ZA9010190B (fi)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5714146A (en) * 1992-08-26 1998-02-03 Board Of Regents Of The University Of Washington IL-4 bone therapy
ZA946765B (en) 1993-09-02 1996-02-15 Dartmouth College Methods of prolonged suppression of humoral immunity
US5914110A (en) * 1993-09-07 1999-06-22 Smithkline Beecham Corporation Recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
EP0730609B1 (en) * 1993-09-07 2005-01-05 Smithkline Beecham Corporation Recombinant il4 antibodies useful in treatment of il4 mediated disorders
US5928904A (en) * 1993-09-07 1999-07-27 Smithkline Beecham Corporation DNA encoding recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
US20020193575A1 (en) 1993-09-07 2002-12-19 Smithkline Beecham P.L.C. Recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
US5597710A (en) * 1994-03-10 1997-01-28 Schering Corporation Humanized monoclonal antibodies against human interleukin-4
US5705154A (en) * 1995-03-08 1998-01-06 Schering Corporation Humanized monoclonal antibodies against human interleukin-4
EP2301567A1 (en) * 1997-02-28 2011-03-30 Enzo Therapeutics, Inc. Selective immune down regulation (SIDR) for transplantation
EP1141286B1 (en) 1998-12-14 2006-10-18 Genetics Institute, LLC Cytokine receptor chain
US7553487B2 (en) 1998-12-14 2009-06-30 Genetics Institute, Llc Method and compositions for treating asthma
EP1142961B1 (en) * 2000-04-06 2008-08-06 FUJIFILM Corporation Dye complex and optical information recording medium
WO2001092340A2 (en) 2000-05-26 2001-12-06 Immunex Corporation Use of interleukin-4 antagonists and compositions thereof
AU2001273413A1 (en) * 2000-07-12 2002-01-21 Immunex Corporation Method for treating cancer using an interleukin- 4 antagonist
US20030170258A1 (en) * 2001-05-09 2003-09-11 Enzo Therapeutics, Inc. Novel processes implementing selective immune down regulation (SIDR)
FR2838444B1 (fr) * 2002-04-10 2016-01-01 Neovacs Nouveaux peptides et leur application en therapeutique
US20070104710A1 (en) * 2002-06-28 2007-05-10 Domants Limited Ligand that has binding specificity for IL-4 and/or IL-13
WO2004003156A2 (en) * 2002-07-01 2004-01-08 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Il-21 as a regulator of immunoglobin production
US20110223168A1 (en) * 2002-12-27 2011-09-15 Greg Winter Ligand that has binding specificity for il-4 and/or il-13
WO2004096849A2 (en) * 2003-04-25 2004-11-11 University Of Manitoba Peptide-based cytokine/chemokine vaccines against allergy
UA93653C2 (ru) 2003-11-07 2011-03-10 Иммунекс Корпорейшн Выделенное антитело, kotopoe специфически связывается c человеческим рецептором il-4 (il-4r)
US7674459B2 (en) 2003-12-23 2010-03-09 Genentech, Inc. Treatment of cancer with a novel anti-IL13 monoclonal antibody
US7501121B2 (en) 2004-06-17 2009-03-10 Wyeth IL-13 binding agents
AR049390A1 (es) 2004-06-09 2006-07-26 Wyeth Corp Anticuerpos contra la interleuquina-13 humana y usos de los mismos
AR050044A1 (es) * 2004-08-03 2006-09-20 Novartis Ag Anticuerpo especifico de il-4
EP2365983B1 (en) * 2008-11-17 2016-12-28 Københavns Universitet Il-4-derived peptides for modulation of the chronic inflammatory response and treatment of autoimmune diseases
TWI586806B (zh) 2010-04-23 2017-06-11 建南德克公司 異多聚體蛋白質之製造
US10689447B2 (en) 2011-02-04 2020-06-23 Genentech, Inc. Fc variants and methods for their production
AR085138A1 (es) 2011-02-04 2013-09-11 Genentech Inc VARIANTES DE Fc Y METODOS PARA SU PRODUCCION
MX2015013901A (es) * 2013-04-05 2015-12-11 Genentech Inc Anticuerpos anti-il-4 y anticuerpos biespecificos y sus usos.
KR102373930B1 (ko) 2013-09-13 2022-03-11 제넨테크, 인크. 정제된 재조합 폴리펩티드를 포함하는 방법 및 조성물
JP6546178B2 (ja) 2013-09-13 2019-07-17 ジェネンテック， インコーポレイテッド 細胞株中の宿主細胞タンパク質及び組換えポリペプチド産物を検出及び定量化するための組成物並びに方法
KR102652133B1 (ko) * 2018-02-01 2024-03-29 베이징 카윈 테크놀로지 쉐어-홀딩 컴퍼니 리미티드 IL-4Rα 항체 및 그 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT83761B (pt) * 1985-11-19 1989-06-30 Schering Biotech Corp Metodo para a producao de interleuquina-4 de mamifero
US5013824A (en) * 1985-11-19 1991-05-07 Schering Corporation Human interleukin-4 peptides and conjugates thereof
US5041381A (en) * 1986-07-03 1991-08-20 Schering Corporation Monoclonal antibodies against human interleukin-4 and hybridomas producing the same
ZA872781B (en) 1986-05-19 1987-10-05 Immunology Ventures B-cell stimulating factor
HU211059B (en) * 1988-02-02 1995-10-30 Schering Biotech Corp Method for producing pharmaceutical compositions usable for reducing immunglobulin e responses, containing human il-4 antibodies

Also Published As

Publication number Publication date
MX9203401A (es) 1992-07-01
AU7176291A (en) 1991-07-18
NO922457L (no) 1992-06-19
IE74708B1 (en) 1997-07-30
WO1991009059A1 (en) 1991-06-27
MY106507A (en) 1995-06-30
DE69026627T2 (de) 1996-08-22
CZ635290A3 (en) 1997-08-13
ES2085983T3 (es) 1996-06-16
JPH0730116B2 (ja) 1995-04-05
KR920703642A (ko) 1992-12-18
US6358509B1 (en) 2002-03-19
ATE136906T1 (de) 1996-05-15
NZ236511A (en) 1993-02-25
IE904589A1 (en) 1991-07-03
TW221675B (fi) 1994-03-11
NO922457D0 (no) 1992-06-19
DK0506826T3 (da) 1996-05-13
EP0506826A1 (en) 1992-10-07
CA2071908A1 (en) 1991-06-21
FI104180B (fi) 1999-11-30
AU639754B2 (en) 1993-08-05
CZ283050B6 (cs) 1997-12-17
SK635290A3 (en) 1999-06-11
ZA9010190B (en) 1991-08-28
FI922847A (fi) 1992-06-18
PT96230B (pt) 1998-06-30
FI104180B1 (fi) 1999-11-30
GR3020325T3 (en) 1996-09-30
HU9202073D0 (en) 1992-09-28
HU215245B (hu) 1998-11-30
JPH04506359A (ja) 1992-11-05
FI922847A0 (fi) 1992-06-18
KR960016862B1 (ko) 1996-12-23
PT96230A (pt) 1991-10-15
CA2071908C (en) 2002-04-30
DE69026627D1 (de) 1996-05-23
EP0506826B1 (en) 1996-04-17
IL96714A0 (en) 1991-09-16
HUT64568A (en) 1994-01-28
OA09704A (en) 1993-08-30

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