SK279740B6 - Spôsob výroby - Google Patents

Spôsob výroby Download PDF

Info

Publication number
SK279740B6
SK279740B6 SK2409-91A SK240991A SK279740B6 SK 279740 B6 SK279740 B6 SK 279740B6 SK 240991 A SK240991 A SK 240991A SK 279740 B6 SK279740 B6 SK 279740B6
Authority
SK
Slovakia
Prior art keywords
ifosfamide
microcrystalline cellulose
weight
capsules
parts
Prior art date
Application number
SK2409-91A
Other languages
English (en)
Slovak (sk)
Inventor
Dieter Sauerbier
J�Rgen Engel
Eckhard Milsmann
Klaus Molge
Otto Isaac
Original Assignee
Asta Medica Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Aktiengesellschaft filed Critical Asta Medica Aktiengesellschaft
Publication of SK279740B6 publication Critical patent/SK279740B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK2409-91A 1990-08-03 1991-08-02 Spôsob výroby SK279740B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4024683 1990-08-03
SG181694A SG181694G (en) 1990-08-03 1994-12-30 Solid oral administration forms containing ifosfamide as active agent

Publications (1)

Publication Number Publication Date
SK279740B6 true SK279740B6 (sk) 1999-03-12

Family

ID=25895607

Family Applications (2)

Application Number Title Priority Date Filing Date
SK2409-91A SK279740B6 (sk) 1990-08-03 1991-08-02 Spôsob výroby
SK543-98A SK279739B6 (sk) 1990-08-03 1998-04-27 Pevné ifosfamidové prípravky na orálnu aplikáciu a

Family Applications After (1)

Application Number Title Priority Date Filing Date
SK543-98A SK279739B6 (sk) 1990-08-03 1998-04-27 Pevné ifosfamidové prípravky na orálnu aplikáciu a

Country Status (33)

Country Link
US (1) US5158776A (no)
EP (1) EP0469440B1 (no)
JP (2) JP3061898B2 (no)
KR (1) KR0177170B1 (no)
CN (1) CN1046851C (no)
AR (1) AR247484A1 (no)
AT (1) ATE110261T1 (no)
AU (2) AU643309B2 (no)
BG (1) BG60900B1 (no)
CA (1) CA2048367C (no)
CZ (1) CZ280475B6 (no)
DE (2) DE59102620D1 (no)
DK (1) DK0469440T3 (no)
EG (1) EG19690A (no)
ES (1) ES2058999T3 (no)
FI (1) FI97951C (no)
HK (1) HK15695A (no)
HR (1) HRP920575B1 (no)
HU (1) HU206268B (no)
IE (1) IE66378B1 (no)
IL (1) IL99031A (no)
LT (1) LT3528B (no)
LV (1) LV10043B (no)
MC (1) MC2274A1 (no)
MX (1) MX9100441A (no)
NO (1) NO178252C (no)
NZ (1) NZ239222A (no)
PT (1) PT98532B (no)
RO (1) RO113611B1 (no)
SG (1) SG181694G (no)
SI (1) SI9111342B (no)
SK (2) SK279740B6 (no)
ZA (1) ZA916124B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7966694A (en) * 1993-07-21 1996-05-02 University Of Kentucky Research Foundation, The A multicompartment hard capsule with control release properties
ITFI970184A1 (it) * 1997-07-30 1999-01-30 Menarini Farma Ind Composizioni farmaceutiche contenenti vitamina d e calcio,loro preparazione ed uso terapeutico
DE19733305A1 (de) * 1997-08-01 1999-02-04 Asta Medica Ag Pharmazeutische Zusammensetzung enthaltend Ifosfamid und Carnitin
US6103297A (en) * 1998-01-14 2000-08-15 Matsushita Electronics Corporation Method of manufacturing cathode-ray tube
DE19826517B4 (de) * 1998-06-15 2006-03-23 Baxter Healthcare S.A. Verfahren zur Herstellung von Filmtabletten mit Cyclophosphamid als Wirkstoff und daraus hergestellte Cyclophosphamid-Filmtablette
US20040253307A1 (en) * 2003-02-04 2004-12-16 Brian Hague Sugar-free oral transmucosal solid dosage forms and uses thereof
DE102005008797A1 (de) * 2005-02-25 2006-09-07 Baxter International Inc., Deerfield Trofosfamid-haltige Filmtabletten und Verfahren zu deren Herstellung
JP6556753B2 (ja) * 2014-01-06 2019-08-07 アイアン・セラピューティクス・ホールディングス・アクチェンゲゼルシャフト トリマルトール鉄（ｉｉｉ）の投与計画
GB201418710D0 (en) 2014-10-21 2014-12-03 Iron Therapeutics Holdings Ag Dosage regimen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5646807A (en) * 1979-09-27 1981-04-28 Japan Atom Energy Res Inst Production of composition of complex gradually releasing physiologically active substance
DE3111428A1 (de) * 1981-03-24 1982-10-07 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
US4618692A (en) * 1981-09-03 1986-10-21 Asta-Werke Aktiengesellschaft 4-carbamoyloxy-oxazaphosphorins
US5019385A (en) * 1984-11-09 1991-05-28 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Novel lymphopine LK 2 and pharmaceutic compositions containing same
EP0254902B1 (de) * 1986-07-11 1991-08-28 ASTA Pharma Aktiengesellschaft Lösungen von Oxazaphosphorinen mit verbesserter Stabilität und Verfahren zu deren Herstellung
DE3804686A1 (de) * 1988-02-15 1989-08-24 Henkel Kgaa Arzneimittel mit einer kombination von cytostatika bzw. hormontherapeutika und phosphonoderivaten

Also Published As

Publication number Publication date
PT98532A (pt) 1992-06-30
HRP920575B1 (en) 1999-04-30
FI97951B (fi) 1996-12-13
LT3528B (en) 1995-11-27
EP0469440A1 (de) 1992-02-05
NO178252B (no) 1995-11-13
IL99031A0 (en) 1992-07-15
CS240991A3 (en) 1992-03-18
DK0469440T3 (da) 1994-11-14
EG19690A (en) 1995-09-30
EP0469440B1 (de) 1994-08-24
FI97951C (fi) 1997-03-25
NZ239222A (en) 1993-01-27
JPH04243828A (ja) 1992-08-31
NO913019D0 (no) 1991-08-02
HU206268B (en) 1992-10-28
RO113611B1 (ro) 1998-09-30
JP2000229860A (ja) 2000-08-22
HK15695A (en) 1995-02-10
MC2274A1 (fr) 1993-06-23
ATE110261T1 (de) 1994-09-15
SI9111342A (sl) 1998-04-30
AR247484A1 (es) 1995-01-31
IL99031A (en) 1996-09-04
DE59102620D1 (de) 1994-09-29
CN1058715A (zh) 1992-02-19
IE912774A1 (en) 1992-02-12
BG60900B1 (bg) 1996-06-28
SG181694G (en) 1995-05-12
AU649184B2 (en) 1994-05-12
FI913710A0 (fi) 1991-08-02
KR920003963A (ko) 1992-03-27
NO913019L (no) 1992-02-04
CA2048367C (en) 2000-05-23
AU643309B2 (en) 1993-11-11
LV10043A (lv) 1994-05-10
AU8158991A (en) 1992-02-06
FI913710A (fi) 1992-02-04
PT98532B (pt) 1999-01-29
SK279739B6 (sk) 1999-03-12
BG94934A (bg) 1993-12-24
JP3545300B2 (ja) 2004-07-21
HU912594D0 (en) 1992-01-28
AU4483693A (en) 1993-11-11
CN1046851C (zh) 1999-12-01
CA2048367A1 (en) 1992-02-04
KR0177170B1 (ko) 1999-03-20
US5158776A (en) 1992-10-27
DE4124481A1 (de) 1992-02-06
HRP920575A2 (en) 1995-04-30
ZA916124B (en) 1992-04-29
ES2058999T3 (es) 1994-11-01
MX9100441A (es) 1992-04-01
LTIP921A (en) 1995-03-27
LV10043B (en) 1995-06-20
SI9111342B (sl) 1998-10-31
IE66378B1 (en) 1995-12-27
HUT59316A (en) 1992-05-28
CZ280475B6 (cs) 1996-01-17
JP3061898B2 (ja) 2000-07-10
NO178252C (no) 1996-02-21

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20100802