SK1897A3 - Benzamidines, its preparation, pharmaceutical composition containing them and their use - Google Patents

Benzamidines, its preparation, pharmaceutical composition containing them and their use Download PDF

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Publication number
SK1897A3
SK1897A3 SK18-97A SK1897A SK1897A3 SK 1897 A3 SK1897 A3 SK 1897A3 SK 1897 A SK1897 A SK 1897A SK 1897 A3 SK1897 A3 SK 1897A3
Authority
SK
Slovakia
Prior art keywords
formula
compound
pharmaceutical composition
treatment
phenol
Prior art date
Application number
SK18-97A
Other languages
English (en)
Slovak (sk)
Inventor
Ralf Anderskewitz
Kurt Schromm
Ernst-Otto Renth
Franz Birke
Armin Fugner
Hubert Heuer
Christopher Meade
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of SK1897A3 publication Critical patent/SK1897A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SK18-97A 1994-07-13 1995-06-03 Benzamidines, its preparation, pharmaceutical composition containing them and their use SK1897A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4424714A DE4424714A1 (de) 1994-07-13 1994-07-13 Neue chemische Verbindung, ihre Herstellung und ihre Verwendung als Arnzneistoff
PCT/EP1995/002113 WO1996002496A1 (de) 1994-07-13 1995-06-03 Neue chemische verbindung, ihre herstellung und ihre verwendung als arzneistoff

Publications (1)

Publication Number Publication Date
SK1897A3 true SK1897A3 (en) 1997-08-06

Family

ID=6523048

Family Applications (1)

Application Number Title Priority Date Filing Date
SK18-97A SK1897A3 (en) 1994-07-13 1995-06-03 Benzamidines, its preparation, pharmaceutical composition containing them and their use

Country Status (25)

Country Link
US (1) US5686496A (ko)
EP (1) EP0770058A1 (ko)
JP (1) JPH10502646A (ko)
KR (1) KR970704674A (ko)
CN (1) CN1152303A (ko)
AU (1) AU2736895A (ko)
BG (1) BG101104A (ko)
BR (1) BR9508395A (ko)
CA (1) CA2194886A1 (ko)
CO (1) CO4410185A1 (ko)
CZ (1) CZ8297A3 (ko)
DE (1) DE4424714A1 (ko)
EE (1) EE9700065A (ko)
FI (1) FI970095A0 (ko)
HR (1) HRP950363A2 (ko)
HU (1) HUT76827A (ko)
IL (1) IL114572A0 (ko)
MX (1) MX9700245A (ko)
NO (1) NO970123D0 (ko)
PE (1) PE35196A1 (ko)
PL (1) PL318114A1 (ko)
SK (1) SK1897A3 (ko)
WO (1) WO1996002496A1 (ko)
YU (1) YU45395A (ko)
ZA (1) ZA955781B (ko)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6486181B1 (en) 1992-08-28 2002-11-26 City Of Hope Human leukocutye 12-lipoxygenase and its role in the pathogenesis of disease states
US6191169B1 (en) 1992-08-28 2001-02-20 City Of Hope Human leukocyte 12-lipoxygenase and its role in the pathogenesis of disease states
AU5857296A (en) * 1995-05-17 1996-11-29 Eli Lilly And Company Use of leukotriene antagonists for alzheimer's disease
DE19546452A1 (de) * 1995-12-13 1997-06-19 Boehringer Ingelheim Kg Neue Phenylamidinderivate, Verfahren zu ihrer Herstelung und ihre Verwendung als Arzneimittel
DE19636689A1 (de) * 1996-09-10 1998-03-12 Boehringer Ingelheim Kg Neue Benzamidinderivate
DE19718334A1 (de) 1997-04-30 1998-11-05 Boehringer Ingelheim Pharma Neue Benzylaminderivate und Phenylethylaminderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
ID24720A (id) 1997-12-12 2000-08-03 Novartis Ag Senyawa amidino tersubstitusi dalam perawatan penyakit gangguan paru-paru kronis
DE19834713A1 (de) * 1998-07-31 2000-02-03 Boehringer Ingelheim Pharma Neue Phenylethylaminderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US6528491B2 (en) * 2000-10-24 2003-03-04 Boehringer Ingelheim Pharma Kg Pyranoside derivatives
EP1353661A2 (en) * 2001-01-16 2003-10-22 Boehringer Ingelheim Pharma GmbH & Co.KG Use of an ltb4 antagonist for the treatment and/or prevention of diseases caused by increased expression of mucin genes
KR20040036908A (ko) * 2001-08-31 2004-05-03 뉴로겜 인터내셔널 리미티드 아밀로이드증 치료용 아미딘 유도체
WO2004099783A2 (en) * 2003-05-06 2004-11-18 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g-protein-coupled receptor ltb4 (ltb4)
US7262223B2 (en) * 2004-01-23 2007-08-28 Neurochem (International) Limited Amidine derivatives for treating amyloidosis
KR100682199B1 (ko) * 2004-07-05 2007-02-12 동화약품공업주식회사 알러지성 염증 질환의 예방 및 치료용 조성물
JP3983272B2 (ja) * 2004-07-14 2007-09-26 有限会社 炎症研究所 腫瘍転移の抑制方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0518818A3 (en) * 1991-06-11 1993-04-28 Ciba-Geigy Ag Arylethers, their manufacture and use as medicament
AU673343B2 (en) * 1992-02-05 1996-11-07 Boehringer Ingelheim International Gmbh Novel amidine derivatives, their preparation and their use as mediaments with LTB4 antagonistic effect

Also Published As

Publication number Publication date
MX9700245A (es) 1997-05-31
ZA955781B (en) 1996-02-22
CZ8297A3 (en) 1997-09-17
PE35196A1 (es) 1996-09-05
FI970095A (fi) 1997-01-10
HUT76827A (en) 1997-11-28
BR9508395A (pt) 1997-12-23
EE9700065A (et) 1997-08-15
EP0770058A1 (de) 1997-05-02
WO1996002496A1 (de) 1996-02-01
NO970123L (no) 1997-01-10
AU2736895A (en) 1996-02-16
HRP950363A2 (en) 1997-08-31
DE4424714A1 (de) 1996-01-18
CN1152303A (zh) 1997-06-18
HU9700060D0 (en) 1997-02-28
KR970704674A (ko) 1997-09-06
YU45395A (sh) 1997-12-05
JPH10502646A (ja) 1998-03-10
IL114572A0 (en) 1995-11-27
FI970095A0 (fi) 1997-01-10
CO4410185A1 (es) 1997-01-09
BG101104A (en) 1998-04-30
US5686496A (en) 1997-11-11
NO970123D0 (no) 1997-01-10
PL318114A1 (en) 1997-05-12
CA2194886A1 (en) 1996-02-01

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