SK159895A3 - Novel (1-heteroazolyl-1-heterocyclyl)alkane derivatives and their use as neuroprotective agents - Google Patents

Novel (1-heteroazolyl-1-heterocyclyl)alkane derivatives and their use as neuroprotective agents Download PDF

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Publication number
SK159895A3
SK159895A3 SK1598-95A SK159895A SK159895A3 SK 159895 A3 SK159895 A3 SK 159895A3 SK 159895 A SK159895 A SK 159895A SK 159895 A3 SK159895 A3 SK 159895A3
Authority
SK
Slovakia
Prior art keywords
group
formula
lower alkyl
compound
methyl
Prior art date
Application number
SK1598-95A
Other languages
English (en)
Slovak (sk)
Inventor
Bernard R Boar
Alan J Cross
Duncan A Gray
Alfred R Green
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of SK159895A3 publication Critical patent/SK159895A3/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK1598-95A 1993-07-06 1994-07-05 Novel (1-heteroazolyl-1-heterocyclyl)alkane derivatives and their use as neuroprotective agents SK159895A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE19939302332A SE9302332D0 (sv) 1993-07-06 1993-07-06 New compounds
PCT/SE1994/000663 WO1995001979A1 (en) 1993-07-06 1994-07-05 Novel (1-heteroazolyl-1-heterocyclyl)alkane derivatives and their use as neuroprotective agents

Publications (1)

Publication Number Publication Date
SK159895A3 true SK159895A3 (en) 1996-09-04

Family

ID=20390539

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1598-95A SK159895A3 (en) 1993-07-06 1994-07-05 Novel (1-heteroazolyl-1-heterocyclyl)alkane derivatives and their use as neuroprotective agents

Country Status (24)

Country Link
US (2) US5731335A (zh)
EP (1) EP0707584A1 (zh)
JP (1) JPH08512312A (zh)
CN (1) CN1126994A (zh)
AU (1) AU691506B2 (zh)
BR (1) BR9406923A (zh)
CA (1) CA2164856A1 (zh)
CZ (1) CZ5396A3 (zh)
EE (1) EE03193B1 (zh)
EG (1) EG20569A (zh)
FI (1) FI960076A0 (zh)
HU (1) HUT75097A (zh)
IL (1) IL110157A (zh)
IS (1) IS4182A (zh)
MX (1) MX9405110A (zh)
NO (1) NO305955B1 (zh)
NZ (1) NZ268689A (zh)
PL (1) PL176471B1 (zh)
RU (1) RU2124011C1 (zh)
SE (1) SE9302332D0 (zh)
SG (1) SG64891A1 (zh)
SK (1) SK159895A3 (zh)
WO (1) WO1995001979A1 (zh)
ZA (1) ZA944569B (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9604242D0 (en) 1996-02-28 1996-05-01 Glaxo Wellcome Inc Chemical compounds
DE19645313A1 (de) 1996-11-04 1998-05-07 Basf Ag Substituierte 3-Benzylpyrazole
EP1047423B1 (en) 1997-11-19 2006-05-10 Takeda Pharmaceutical Company Limited Novel apoptosis inhibitors
AR035016A1 (es) 1999-08-25 2004-04-14 Takeda Chemical Industries Ltd Composicion de azol promotor de produccion/secrecion de neurotrofina, compuesto prodroga del mismo, composicion farmaceutica que lo comprende y uso del mismo para preparar esta ultima.
AU2001245897B2 (en) 2000-03-24 2006-07-06 Euro-Celtique S.A. Aryl substituted pyrazoles, triazoles and tetrazoles as sodium channel blocker
ES2287896T3 (es) 2004-01-12 2007-12-16 Laboratoires Serono Sa Derivados de tiazol y uso de los mismos.
WO2006031631A1 (en) * 2004-09-10 2006-03-23 Syngenta Limited Substituted isoxazoles as fungicides
US7888376B2 (en) * 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
WO2008147786A1 (en) * 2007-05-23 2008-12-04 Allergan, Inc. ((bicylicheteroaryl) imidazolyl) methylheteroaryl compounds as adrenergic receptor agonists
WO2009123164A1 (ja) * 2008-04-02 2009-10-08 塩野義製薬株式会社 血管内皮リパーゼ阻害活性を有するヘテロ環誘導体
US20130252972A1 (en) * 2010-07-19 2013-09-26 Syngenta Crop Protection Llc Isoxazole, isothiazole, furane and thiophene compounds as microbicides
EP2447261A1 (en) * 2010-10-29 2012-05-02 Basf Se Pyrrole, furane and thiophene derivatives and their use as fungicides
JP2014525442A (ja) * 2011-08-30 2014-09-29 ヴィアメット ファーマスーティカルズ,インコーポレイテッド 金属酵素阻害化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58150576A (ja) * 1982-03-03 1983-09-07 Sumitomo Chem Co Ltd 新規な1,2,4−オキサジアゾ−ル誘導体
JPH01249760A (ja) * 1988-03-29 1989-10-05 Yamaha Corp ホトクロミック化合物
US5068237A (en) * 1990-05-21 1991-11-26 Warner-Lambert Company Substituted furans and derivatives thereof acting at muscarinic receptors
CA2126976A1 (en) * 1991-12-31 1993-07-08 Hisashi Takasugi Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity

Also Published As

Publication number Publication date
CZ5396A3 (en) 1996-06-12
PL312417A1 (en) 1996-04-15
SG64891A1 (en) 1999-05-25
AU691506B2 (en) 1998-05-21
EP0707584A1 (en) 1996-04-24
IS4182A (is) 1995-01-07
BR9406923A (pt) 1996-07-30
WO1995001979A1 (en) 1995-01-19
RU2124011C1 (ru) 1998-12-27
MX9405110A (es) 1995-01-31
US5607956A (en) 1997-03-04
CA2164856A1 (en) 1995-01-19
ZA944569B (en) 1995-02-15
HUT75097A (en) 1997-04-28
FI960076A (fi) 1996-01-08
IL110157A0 (en) 1994-10-07
FI960076A0 (fi) 1996-01-08
NO960028L (no) 1996-02-27
IL110157A (en) 2000-01-31
CN1126994A (zh) 1996-07-17
EG20569A (en) 1999-08-30
PL176471B1 (pl) 1999-06-30
NZ268689A (en) 1997-11-24
SE9302332D0 (sv) 1993-07-06
JPH08512312A (ja) 1996-12-24
HU9503744D0 (en) 1996-02-28
EE03193B1 (et) 1999-06-15
NO960028D0 (no) 1996-01-04
NO305955B1 (no) 1999-08-23
AU7197794A (en) 1995-02-06
US5731335A (en) 1998-03-24

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