SK159296A3 - 4-carbamoyloxy-piperidine-1-carboxylic acid esters and their use - Google Patents

4-carbamoyloxy-piperidine-1-carboxylic acid esters and their use Download PDF

Info

Publication number
SK159296A3
SK159296A3 SK1592-96A SK159296A SK159296A3 SK 159296 A3 SK159296 A3 SK 159296A3 SK 159296 A SK159296 A SK 159296A SK 159296 A3 SK159296 A3 SK 159296A3
Authority
SK
Slovakia
Prior art keywords
alkyl
hydrogen
phenyl
alkylcarbonyl
alkoxycarbonyl
Prior art date
Application number
SK1592-96A
Other languages
English (en)
Slovak (sk)
Inventor
Thomas J Commons
Christa M Laclair
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of SK159296A3 publication Critical patent/SK159296A3/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/46Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK1592-96A 1994-06-13 1995-04-18 4-carbamoyloxy-piperidine-1-carboxylic acid esters and their use SK159296A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/259,229 US5527804A (en) 1994-06-13 1994-06-13 4-carbamoyloxy-piperidine-1-carboxylic acid esters: inhibitors or cholesterol absorption
PCT/US1995/004938 WO1995034539A1 (en) 1994-06-13 1995-04-18 4-carbamoyloxy-piperidine-1-carboxylic acid esters: inhibitors of cholesterol absorption

Publications (1)

Publication Number Publication Date
SK159296A3 true SK159296A3 (en) 1997-07-09

Family

ID=22984090

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1592-96A SK159296A3 (en) 1994-06-13 1995-04-18 4-carbamoyloxy-piperidine-1-carboxylic acid esters and their use

Country Status (13)

Country Link
US (1) US5527804A (cs)
EP (1) EP0765312A1 (cs)
JP (1) JPH10501262A (cs)
CN (1) CN1150798A (cs)
AU (1) AU701447B2 (cs)
BR (1) BR9507992A (cs)
CA (1) CA2192459A1 (cs)
CZ (1) CZ364896A3 (cs)
HU (1) HUT76474A (cs)
NZ (1) NZ284371A (cs)
PL (1) PL317660A1 (cs)
SK (1) SK159296A3 (cs)
WO (1) WO1995034539A1 (cs)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL95994A0 (en) * 1989-11-15 1991-07-18 American Home Prod Carbamate esters and pharmaceutical compositions containing them
US5112859A (en) * 1990-09-14 1992-05-12 American Home Products Corporation Biphenyl amide cholesterol ester hydrolase inhibitors
US5169844A (en) * 1991-12-20 1992-12-08 American Home Products Corporation 4-substituted piperidinecarboxylic acid esters: inhibition of cholesterol absorption
US5952354A (en) * 1993-07-21 1999-09-14 American Home Products Corporation Tris carbamic acid esters: inhibitors of cholesterol absorption

Also Published As

Publication number Publication date
AU701447B2 (en) 1999-01-28
WO1995034539A1 (en) 1995-12-21
AU2296495A (en) 1996-01-05
CZ364896A3 (en) 1997-10-15
CN1150798A (zh) 1997-05-28
NZ284371A (en) 1999-01-28
US5527804A (en) 1996-06-18
JPH10501262A (ja) 1998-02-03
CA2192459A1 (en) 1995-12-21
PL317660A1 (en) 1997-04-28
BR9507992A (pt) 1997-08-05
HUT76474A (en) 1997-09-29
HU9603414D0 (en) 1997-02-28
EP0765312A1 (en) 1997-04-02

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