BR9507992A - Esteres do ácido 4-carbamoilóxi-piperdino-1-carboxílico inibidores da absorção de colesterol - Google Patents

Esteres do ácido 4-carbamoilóxi-piperdino-1-carboxílico inibidores da absorção de colesterol

Info

Publication number
BR9507992A
BR9507992A BR9507992A BR9507992A BR9507992A BR 9507992 A BR9507992 A BR 9507992A BR 9507992 A BR9507992 A BR 9507992A BR 9507992 A BR9507992 A BR 9507992A BR 9507992 A BR9507992 A BR 9507992A
Authority
BR
Brazil
Prior art keywords
piperdino
carbamoyloxy
carboxylic acid
cholesterol absorption
absorption inhibitors
Prior art date
Application number
BR9507992A
Other languages
English (en)
Inventor
Thomas Joseph Commons
Christa Marie Laclair
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of BR9507992A publication Critical patent/BR9507992A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
BR9507992A 1994-06-13 1995-04-18 Esteres do ácido 4-carbamoilóxi-piperdino-1-carboxílico inibidores da absorção de colesterol BR9507992A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/259,229 US5527804A (en) 1994-06-13 1994-06-13 4-carbamoyloxy-piperidine-1-carboxylic acid esters: inhibitors or cholesterol absorption
PCT/US1995/004938 WO1995034539A1 (en) 1994-06-13 1995-04-18 4-carbamoyloxy-piperidine-1-carboxylic acid esters: inhibitors of cholesterol absorption

Publications (1)

Publication Number Publication Date
BR9507992A true BR9507992A (pt) 1997-08-05

Family

ID=22984090

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9507992A BR9507992A (pt) 1994-06-13 1995-04-18 Esteres do ácido 4-carbamoilóxi-piperdino-1-carboxílico inibidores da absorção de colesterol

Country Status (13)

Country Link
US (1) US5527804A (pt)
EP (1) EP0765312A1 (pt)
JP (1) JPH10501262A (pt)
CN (1) CN1150798A (pt)
AU (1) AU701447B2 (pt)
BR (1) BR9507992A (pt)
CA (1) CA2192459A1 (pt)
CZ (1) CZ364896A3 (pt)
HU (1) HUT76474A (pt)
NZ (1) NZ284371A (pt)
PL (1) PL317660A1 (pt)
SK (1) SK159296A3 (pt)
WO (1) WO1995034539A1 (pt)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL95994A0 (en) * 1989-11-15 1991-07-18 American Home Prod Carbamate esters and pharmaceutical compositions containing them
US5112859A (en) * 1990-09-14 1992-05-12 American Home Products Corporation Biphenyl amide cholesterol ester hydrolase inhibitors
US5169844A (en) * 1991-12-20 1992-12-08 American Home Products Corporation 4-substituted piperidinecarboxylic acid esters: inhibition of cholesterol absorption
US5952354A (en) * 1993-07-21 1999-09-14 American Home Products Corporation Tris carbamic acid esters: inhibitors of cholesterol absorption

Also Published As

Publication number Publication date
JPH10501262A (ja) 1998-02-03
NZ284371A (en) 1999-01-28
CA2192459A1 (en) 1995-12-21
AU701447B2 (en) 1999-01-28
EP0765312A1 (en) 1997-04-02
US5527804A (en) 1996-06-18
CN1150798A (zh) 1997-05-28
PL317660A1 (en) 1997-04-28
HU9603414D0 (en) 1997-02-28
CZ364896A3 (en) 1997-10-15
SK159296A3 (en) 1997-07-09
HUT76474A (en) 1997-09-29
AU2296495A (en) 1996-01-05
WO1995034539A1 (en) 1995-12-21

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Legal Events

Date Code Title Description
FB36 Technical and formal requirements: requirement - article 36 of industrial property law
FA8 Dismissal: dismissal - article 36, par. 1 of industrial property law