SK14182003A3 - Homogenizát pre implantáty a mikročastice - Google Patents

Homogenizát pre implantáty a mikročastice Download PDF

Info

Publication number
SK14182003A3
SK14182003A3 SK1418-2003A SK14182003A SK14182003A3 SK 14182003 A3 SK14182003 A3 SK 14182003A3 SK 14182003 A SK14182003 A SK 14182003A SK 14182003 A3 SK14182003 A3 SK 14182003A3
Authority
SK
Slovakia
Prior art keywords
grinding
temperature
cooled
active ingredient
mill
Prior art date
Application number
SK1418-2003A
Other languages
English (en)
Slovak (sk)
Inventor
Gregor Sch�Tz
Brigitte Freudensprung
Original Assignee
Hexal Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26009392&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK14182003(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE2001125509 external-priority patent/DE10125509A1/de
Priority claimed from DE2002108382 external-priority patent/DE10208382A1/de
Application filed by Hexal Ag filed Critical Hexal Ag
Publication of SK14182003A3 publication Critical patent/SK14182003A3/sk

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Steroid Compounds (AREA)
SK1418-2003A 2001-05-23 2002-05-23 Homogenizát pre implantáty a mikročastice SK14182003A3 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE2001125509 DE10125509A1 (de) 2001-05-23 2001-05-23 Lösungsmittelfreie Homogenisatherstellung
DE2002108382 DE10208382A1 (de) 2002-02-27 2002-02-27 Homogenisat für Implantate und Mikropartikel
PCT/EP2002/005680 WO2002094226A1 (fr) 2001-05-23 2002-05-23 Homogeneisat pour implants et microparticules

Publications (1)

Publication Number Publication Date
SK14182003A3 true SK14182003A3 (sk) 2004-05-04

Family

ID=26009392

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1418-2003A SK14182003A3 (sk) 2001-05-23 2002-05-23 Homogenizát pre implantáty a mikročastice

Country Status (16)

Country Link
US (1) US8501056B2 (fr)
EP (1) EP1392248B1 (fr)
JP (1) JP4346909B2 (fr)
AT (1) ATE369122T1 (fr)
BR (1) BR0209914A (fr)
CA (1) CA2449502C (fr)
CY (1) CY1106944T1 (fr)
CZ (1) CZ20033160A3 (fr)
DE (1) DE50210646D1 (fr)
DK (1) DK1392248T3 (fr)
ES (1) ES2290294T3 (fr)
NO (1) NO20035179D0 (fr)
PL (1) PL364054A1 (fr)
PT (1) PT1392248E (fr)
SK (1) SK14182003A3 (fr)
WO (1) WO2002094226A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002094226A1 (fr) 2001-05-23 2002-11-28 Hexal Ag Homogeneisat pour implants et microparticules
FR2879074B1 (fr) * 2004-12-15 2007-08-03 Adisseo France Sas Soc Par Act Granules de principe actif hydrophile
FR2879075B1 (fr) * 2004-12-15 2007-01-19 Adisseo France Sas Soc Par Act Procede de preparation de granules de principe actif hydrophile par extrusion
CN101095941B (zh) * 2006-06-29 2011-04-20 北京博恩特药业有限公司 醋酸亮丙瑞林在预防和治疗老年性骨质疏松中的新用途
US20100291214A1 (en) * 2008-12-23 2010-11-18 Armark Authentication Technologies, Llc Three-dimensional microfiber extrudate structure and process for forming three-dimensional microfiber extrudate structure
WO2010151746A2 (fr) * 2009-06-26 2010-12-29 Armark Authentication Technologies, Llc Structure d'extrudat en microfibres tridimensionnelle et procédé de formation de la structure d'extrudat en microfibre tridimensionnelle
DE102011114864A1 (de) 2011-10-05 2013-04-11 Acino Ag Verfahren zur Herstellung einer homogenen Pulvermischung und Verfahren zur Herstellung eines Implantats sowie Implantat
CN104023704B (zh) * 2011-10-31 2016-08-17 花王株式会社 化妆品
DE102013011399A1 (de) 2012-07-31 2014-02-06 Amw Gmbh Implantat mit Risperidon
WO2016076800A1 (fr) * 2014-11-14 2016-05-19 Nanyang Technological University Composite de magnésium biorésorbable
USD782771S1 (en) 2015-04-03 2017-03-28 Geo Plastics Tight head drum
EP3492070A1 (fr) 2017-11-30 2019-06-05 BIT Pharma GmbH Procédé et dispositif de préparation d'une dispersion solide
USD938128S1 (en) 2020-01-06 2021-12-07 Geo Plastics Nestable drum
USD1001413S1 (en) 2020-06-30 2023-10-10 Geo Plastics Nestable drum

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3992350A (en) * 1972-05-04 1976-11-16 Produits Chimiques Ugine Kuhlmann Process of mixing fillers with polytetrafluorethylene and tetrafluorethylene copolymers
US4016345A (en) 1972-12-22 1977-04-05 E. I. Du Pont De Nemours And Company Process for polymerizing tetrafluoroethylene in aqueous dispersion
FR2418067A1 (fr) * 1978-02-22 1979-09-21 Omya Sa Procede pour incorporer a un polymere des additifs solides, liquides ou pateux a temperature ambiante
EP0300241B1 (fr) * 1987-07-10 1991-09-25 Karl Reinhard Zeiss Procédé de fabrication et d'usinage de mélanges de matière plastique réactive
US4917834A (en) * 1988-11-16 1990-04-17 General Technology Applications, Inc. Method for forming homogeneous blends of particulate materials
CH679207A5 (fr) 1989-07-28 1992-01-15 Debiopharm Sa
US5439688A (en) * 1989-07-28 1995-08-08 Debio Recherche Pharmaceutique S.A. Process for preparing a pharmaceutical composition
US5843347A (en) * 1993-03-23 1998-12-01 Laboratoire L. Lafon Extrusion and freeze-drying method for preparing particles containing an active ingredient
US5456917A (en) * 1993-04-12 1995-10-10 Cambridge Scientific, Inc. Method for making a bioerodible material for the sustained release of a medicament and the material made from the method
DE19545327C2 (de) * 1995-12-05 2001-04-19 Fraunhofer Ges Forschung Verfahren zur Herstellung von hydrophobierten resorbierbaren Polyestern und deren Verwendung
US5817343A (en) * 1996-05-14 1998-10-06 Alkermes, Inc. Method for fabricating polymer-based controlled-release devices
US5945128A (en) 1996-09-04 1999-08-31 Romano Deghenghi Process to manufacture implants containing bioactive peptides
US6177609B1 (en) * 1997-03-10 2001-01-23 Meadox Medicals, Inc. Self-aggregating protein compositions and use as sealants
KR20010023256A (ko) * 1997-08-27 2001-03-26 헥살 아게 용해도와 생체 이용성이 개선된 신규의 멜록시캄 의약조성물
US6455526B1 (en) * 1998-12-16 2002-09-24 Aventis Pharmaceuticals, Inc. Biodegradable polymer encapsulated pharmaceutical compositions and method for preparing the same
HU226586B1 (en) * 1998-12-16 2009-04-28 Aventis Pharma Inc Biodegradable polymer encapsulated serotonin receptor antagonist and method for preparing the same
US6291013B1 (en) 1999-05-03 2001-09-18 Southern Biosystems, Inc. Emulsion-based processes for making microparticles
WO2002094226A1 (fr) 2001-05-23 2002-11-28 Hexal Ag Homogeneisat pour implants et microparticules
US6712850B2 (en) * 2001-11-30 2004-03-30 Ethicon, Inc. Porous tissue scaffolds for the repair and regeneration of dermal tissue
US6894088B2 (en) * 2003-03-24 2005-05-17 Baker Hughes Incorporated Process for homogenizing polyolefin drag reducing agents

Also Published As

Publication number Publication date
WO2002094226A1 (fr) 2002-11-28
CA2449502C (fr) 2010-10-12
US8501056B2 (en) 2013-08-06
PT1392248E (pt) 2007-10-11
ES2290294T3 (es) 2008-02-16
CY1106944T1 (el) 2012-09-26
JP4346909B2 (ja) 2009-10-21
CZ20033160A3 (en) 2004-03-17
EP1392248B1 (fr) 2007-08-08
PL364054A1 (en) 2004-12-13
DK1392248T3 (da) 2007-11-12
BR0209914A (pt) 2004-04-06
ATE369122T1 (de) 2007-08-15
EP1392248A1 (fr) 2004-03-03
CA2449502A1 (fr) 2002-11-28
JP2004530696A (ja) 2004-10-07
NO20035179D0 (no) 2003-11-21
US20040173923A1 (en) 2004-09-09
DE50210646D1 (de) 2007-09-20

Similar Documents

Publication Publication Date Title
SK14182003A3 (sk) Homogenizát pre implantáty a mikročastice
US5192741A (en) Sustained and controlled release of water insoluble polypeptides
RU2018306C1 (ru) Способ получения микрокапсулы полипептида
EP2015737B1 (fr) Procédé de préparation de microsphères à libération contrôlée présentant une dispersibilité et une injectabilité améliorées
CN102149409B (zh) 用于制备微粒的方法
US20060029678A1 (en) Process for the production of implants
SK143494A3 (en) Salts of peptides with carboxy-group terminated polyesters and method of their preparation
ITTO20000963A1 (it) Microparticella a rilascio prolungato e metodo per la sua preparazione.
MXPA06012241A (es) Polimeros de acido polilactico de bajo peso molecular.
EP1924242B1 (fr) Composition pharmaceutique comprenant anastrozole
BRPI0714820A2 (pt) implantes subcutÂneos de liberaÇço de princÍpio ativo em um prolongado perÍodo de tempo
CA2516339A1 (fr) Agent dispersant destine a des preparations a liberation soutenue
DK2485717T3 (en) Continuous release delivery system for a calcium channel blocking agent
KR20180030413A (ko) 약물의 장기간 지속적인 투여를 위한 액체 폴리머 전달 시스템
MXPA05000199A (es) Formulaciones de deposito de duracion corta.
KR20090046837A (ko) 장기간에 걸쳐 활성원을 방출하는 피하 이식제
US20050019367A1 (en) Biodegradable implant comprising a polylactide polymer and a lh-rh analogue
DE10208382A1 (de) Homogenisat für Implantate und Mikropartikel
DE10125509A1 (de) Lösungsmittelfreie Homogenisatherstellung
TWI376241B (en) Pharmaceutical compositions with enhanced stability