PL364054A1 - Homogenised product for implants and microparticles - Google Patents
Homogenised product for implants and microparticlesInfo
- Publication number
- PL364054A1 PL364054A1 PL02364054A PL36405402A PL364054A1 PL 364054 A1 PL364054 A1 PL 364054A1 PL 02364054 A PL02364054 A PL 02364054A PL 36405402 A PL36405402 A PL 36405402A PL 364054 A1 PL364054 A1 PL 364054A1
- Authority
- PL
- Poland
- Prior art keywords
- microparticles
- implants
- homogenised product
- homogenised
- product
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention relates to a method for the solvent-free preparation of a homogenizate, especially for implants or microparticles, wherein one or more polymers and one or more active constituents, as raw materials, are homogenized together below the glass transition temperature of the polymer(s) and, when homogenization is complete, brought to room temperature.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2001125509 DE10125509A1 (en) | 2001-05-23 | 2001-05-23 | Homogenate production, especially for use in implants and/or microparticles, by homogenizing mixture of active agent, e.g. hormone, and polymer below the glass transition temperature in the absence of solvent |
DE2002108382 DE10208382A1 (en) | 2002-02-27 | 2002-02-27 | Homogenate production, especially for use in implants and/or microparticles, by homogenizing mixture of active agent, e.g. hormone, and polymer below the glass transition temperature in the absence of solvent |
PCT/EP2002/005680 WO2002094226A1 (en) | 2001-05-23 | 2002-05-23 | Homogenised product for implants and microparticles |
Publications (1)
Publication Number | Publication Date |
---|---|
PL364054A1 true PL364054A1 (en) | 2004-12-13 |
Family
ID=26009392
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL02364054A PL364054A1 (en) | 2001-05-23 | 2002-05-23 | Homogenised product for implants and microparticles |
Country Status (16)
Country | Link |
---|---|
US (1) | US8501056B2 (en) |
EP (1) | EP1392248B1 (en) |
JP (1) | JP4346909B2 (en) |
AT (1) | ATE369122T1 (en) |
BR (1) | BR0209914A (en) |
CA (1) | CA2449502C (en) |
CY (1) | CY1106944T1 (en) |
CZ (1) | CZ20033160A3 (en) |
DE (1) | DE50210646D1 (en) |
DK (1) | DK1392248T3 (en) |
ES (1) | ES2290294T3 (en) |
NO (1) | NO20035179D0 (en) |
PL (1) | PL364054A1 (en) |
PT (1) | PT1392248E (en) |
SK (1) | SK14182003A3 (en) |
WO (1) | WO2002094226A1 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1392248T3 (en) | 2001-05-23 | 2007-11-12 | Hexal Ag | Process for the preparation of implants by solvent-free preparation of a homogenate |
FR2879075B1 (en) * | 2004-12-15 | 2007-01-19 | Adisseo France Sas Soc Par Act | PROCESS FOR PREPARING EXTRUSION-ACTIVE HYDROPHILIC ACTIVE INGREDIENT PELLETS |
FR2879074B1 (en) * | 2004-12-15 | 2007-08-03 | Adisseo France Sas Soc Par Act | PELLETS OF ACTIVE HYDROPHILIC PRINCIPLE |
CN101095941B (en) * | 2006-06-29 | 2011-04-20 | 北京博恩特药业有限公司 | Novel use of leuprorelin acetate in the preventing and treating of osteoporosis |
US20100291214A1 (en) * | 2008-12-23 | 2010-11-18 | Armark Authentication Technologies, Llc | Three-dimensional microfiber extrudate structure and process for forming three-dimensional microfiber extrudate structure |
WO2010151746A2 (en) * | 2009-06-26 | 2010-12-29 | Armark Authentication Technologies, Llc | Three-dimensional microfiber extrudate structure and process for forming three-dimensional microfiber extrudate structure |
DE102011114864A1 (en) | 2011-10-05 | 2013-04-11 | Acino Ag | Process for producing a homogeneous powder mixture and method for producing an implant and implant |
CN104023704B (en) * | 2011-10-31 | 2016-08-17 | 花王株式会社 | Cosmetics |
DE102013011399A1 (en) | 2012-07-31 | 2014-02-06 | Amw Gmbh | Rod-shaped biodegradable implant useful for maintenance therapy in schizophrenia in patients comprises risperidone |
CN107206120B (en) * | 2014-11-14 | 2021-06-18 | 南洋理工大学 | Bioabsorbable magnesium composite material |
USD782771S1 (en) | 2015-04-03 | 2017-03-28 | Geo Plastics | Tight head drum |
EP3492070A1 (en) | 2017-11-30 | 2019-06-05 | BIT Pharma GmbH | Process and device for preparing a solid dispersion |
USD938128S1 (en) | 2020-01-06 | 2021-12-07 | Geo Plastics | Nestable drum |
USD1001413S1 (en) | 2020-06-30 | 2023-10-10 | Geo Plastics | Nestable drum |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3992350A (en) * | 1972-05-04 | 1976-11-16 | Produits Chimiques Ugine Kuhlmann | Process of mixing fillers with polytetrafluorethylene and tetrafluorethylene copolymers |
US4016345A (en) | 1972-12-22 | 1977-04-05 | E. I. Du Pont De Nemours And Company | Process for polymerizing tetrafluoroethylene in aqueous dispersion |
FR2418067A1 (en) | 1978-02-22 | 1979-09-21 | Omya Sa | Adding solids, liquids or pastes to polymers - at room temp. after low-temp. grinding |
ES2026970T3 (en) * | 1987-07-10 | 1992-05-16 | Karl Reinhard Zeiss | PROCEDURE FOR THE MANUFACTURE AND ELABORATION OF MIXTURES OF REACTIVE SYNTHETIC SUBSTANCES. |
US4917834A (en) * | 1988-11-16 | 1990-04-17 | General Technology Applications, Inc. | Method for forming homogeneous blends of particulate materials |
CH679207A5 (en) * | 1989-07-28 | 1992-01-15 | Debiopharm Sa | |
US5439688A (en) * | 1989-07-28 | 1995-08-08 | Debio Recherche Pharmaceutique S.A. | Process for preparing a pharmaceutical composition |
US5843347A (en) * | 1993-03-23 | 1998-12-01 | Laboratoire L. Lafon | Extrusion and freeze-drying method for preparing particles containing an active ingredient |
US5456917A (en) | 1993-04-12 | 1995-10-10 | Cambridge Scientific, Inc. | Method for making a bioerodible material for the sustained release of a medicament and the material made from the method |
DE19545327C2 (en) | 1995-12-05 | 2001-04-19 | Fraunhofer Ges Forschung | Process for the preparation of hydrophobized resorbable polyesters and their use |
US5817343A (en) * | 1996-05-14 | 1998-10-06 | Alkermes, Inc. | Method for fabricating polymer-based controlled-release devices |
US5945128A (en) | 1996-09-04 | 1999-08-31 | Romano Deghenghi | Process to manufacture implants containing bioactive peptides |
US6177609B1 (en) * | 1997-03-10 | 2001-01-23 | Meadox Medicals, Inc. | Self-aggregating protein compositions and use as sealants |
ZA987800B (en) * | 1997-08-27 | 1999-06-09 | Hexal Ag | Pharmaceutical composition of meloxicam |
US6455526B1 (en) * | 1998-12-16 | 2002-09-24 | Aventis Pharmaceuticals, Inc. | Biodegradable polymer encapsulated pharmaceutical compositions and method for preparing the same |
CN1195497C (en) | 1998-12-16 | 2005-04-06 | 阿温蒂斯药物公司 | Biodegradable polymer encapsulated 5-hydroxytryptamine receptor antagonist and method for preparing the same |
US6291013B1 (en) | 1999-05-03 | 2001-09-18 | Southern Biosystems, Inc. | Emulsion-based processes for making microparticles |
DK1392248T3 (en) | 2001-05-23 | 2007-11-12 | Hexal Ag | Process for the preparation of implants by solvent-free preparation of a homogenate |
US6712850B2 (en) * | 2001-11-30 | 2004-03-30 | Ethicon, Inc. | Porous tissue scaffolds for the repair and regeneration of dermal tissue |
US6894088B2 (en) * | 2003-03-24 | 2005-05-17 | Baker Hughes Incorporated | Process for homogenizing polyolefin drag reducing agents |
-
2002
- 2002-05-23 DK DK02730275T patent/DK1392248T3/en active
- 2002-05-23 PT PT02730275T patent/PT1392248E/en unknown
- 2002-05-23 US US10/479,114 patent/US8501056B2/en not_active Expired - Fee Related
- 2002-05-23 PL PL02364054A patent/PL364054A1/en not_active Application Discontinuation
- 2002-05-23 JP JP2002590945A patent/JP4346909B2/en not_active Expired - Fee Related
- 2002-05-23 CA CA2449502A patent/CA2449502C/en not_active Expired - Fee Related
- 2002-05-23 BR BR0209914-4A patent/BR0209914A/en not_active IP Right Cessation
- 2002-05-23 CZ CZ20033160A patent/CZ20033160A3/en unknown
- 2002-05-23 DE DE50210646T patent/DE50210646D1/en not_active Expired - Lifetime
- 2002-05-23 ES ES02730275T patent/ES2290294T3/en not_active Expired - Lifetime
- 2002-05-23 WO PCT/EP2002/005680 patent/WO2002094226A1/en active IP Right Grant
- 2002-05-23 EP EP02730275A patent/EP1392248B1/en not_active Expired - Lifetime
- 2002-05-23 AT AT02730275T patent/ATE369122T1/en active
- 2002-05-23 SK SK1418-2003A patent/SK14182003A3/en unknown
-
2003
- 2003-11-21 NO NO20035179A patent/NO20035179D0/en unknown
-
2007
- 2007-10-19 CY CY20071101352T patent/CY1106944T1/en unknown
Also Published As
Publication number | Publication date |
---|---|
US20040173923A1 (en) | 2004-09-09 |
BR0209914A (en) | 2004-04-06 |
WO2002094226A1 (en) | 2002-11-28 |
PT1392248E (en) | 2007-10-11 |
ES2290294T3 (en) | 2008-02-16 |
DE50210646D1 (en) | 2007-09-20 |
NO20035179D0 (en) | 2003-11-21 |
US8501056B2 (en) | 2013-08-06 |
JP2004530696A (en) | 2004-10-07 |
SK14182003A3 (en) | 2004-05-04 |
ATE369122T1 (en) | 2007-08-15 |
JP4346909B2 (en) | 2009-10-21 |
CA2449502C (en) | 2010-10-12 |
CZ20033160A3 (en) | 2004-03-17 |
EP1392248A1 (en) | 2004-03-03 |
CY1106944T1 (en) | 2012-09-26 |
CA2449502A1 (en) | 2002-11-28 |
DK1392248T3 (en) | 2007-11-12 |
EP1392248B1 (en) | 2007-08-08 |
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Legal Events
Date | Code | Title | Description |
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REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |