WO2002040963A3 - Biologically active composites and methods for their production and use - Google Patents

Biologically active composites and methods for their production and use Download PDF

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Publication number
WO2002040963A3
WO2002040963A3 PCT/US2001/049948 US0149948W WO0240963A3 WO 2002040963 A3 WO2002040963 A3 WO 2002040963A3 US 0149948 W US0149948 W US 0149948W WO 0240963 A3 WO0240963 A3 WO 0240963A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
biologically active
production
disclosed
composites
Prior art date
Application number
PCT/US2001/049948
Other languages
French (fr)
Other versions
WO2002040963A2 (en
Inventor
Jeffrey G Marx
Erik M Erbe
Original Assignee
Vita Special Purpose Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/939,505 external-priority patent/US6736799B1/en
Application filed by Vita Special Purpose Corp filed Critical Vita Special Purpose Corp
Priority to AU2002241691A priority Critical patent/AU2002241691A1/en
Priority claimed from US10/035,797 external-priority patent/US7045125B2/en
Publication of WO2002040963A2 publication Critical patent/WO2002040963A2/en
Publication of WO2002040963A3 publication Critical patent/WO2002040963A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/43—Hormones, e.g. dexamethasone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/64—Animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Composite Materials (AREA)
  • Materials Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Biologically active composites containing calcium phosphate, more specifically beta-tri-calcium phosphate, and methods of preparing the same are disclosed herein. Also disclosed are methods of restoring an osseous void and complimentary kits for the disclosed composites.
PCT/US2001/049948 2000-10-24 2001-10-23 Biologically active composites and methods for their production and use WO2002040963A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002241691A AU2002241691A1 (en) 2000-10-24 2001-10-23 Biologically active composites and methods for their production and use

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US24290600P 2000-10-24 2000-10-24
US60/242,906 2000-10-24
US09/939,505 US6736799B1 (en) 2000-10-24 2001-08-24 Delivery device for biological composites and method of preparation thereof
US09/939,505 2001-08-24
US10/035,797 US7045125B2 (en) 2000-10-24 2001-10-23 Biologically active composites and methods for their production and use

Publications (2)

Publication Number Publication Date
WO2002040963A2 WO2002040963A2 (en) 2002-05-23
WO2002040963A3 true WO2002040963A3 (en) 2003-01-16

Family

ID=27364903

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/049948 WO2002040963A2 (en) 2000-10-24 2001-10-23 Biologically active composites and methods for their production and use

Country Status (2)

Country Link
AU (1) AU2002241691A1 (en)
WO (1) WO2002040963A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9283074B2 (en) 2002-06-13 2016-03-15 Kensey Nash Bvf Technology, Llc Devices and methods for treating defects in the tissue of a living being

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US6981948B2 (en) 2002-11-18 2006-01-03 Depuy Spine, Inc. Bone marrow aspiration system
US7993578B2 (en) 2004-10-29 2011-08-09 Depuy Spine, Inc. Methods and kits for aseptic filling of products

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4065360A (en) * 1976-04-21 1977-12-27 Kreb Iii Robert J Culturing syringe device
US4801263A (en) * 1986-05-27 1989-01-31 Clark William C Osseous implant syringe
US5772665A (en) * 1993-11-03 1998-06-30 Astra Aktiebolag Device for mixing a pharmaceutical composition with an other agent
US5824084A (en) * 1996-07-03 1998-10-20 The Cleveland Clinic Foundation Method of preparing a composite bone graft
US5939039A (en) * 1997-01-16 1999-08-17 Orthovita, Inc. Methods for production of calcium phosphate

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4065360A (en) * 1976-04-21 1977-12-27 Kreb Iii Robert J Culturing syringe device
US4801263A (en) * 1986-05-27 1989-01-31 Clark William C Osseous implant syringe
US5772665A (en) * 1993-11-03 1998-06-30 Astra Aktiebolag Device for mixing a pharmaceutical composition with an other agent
US5824084A (en) * 1996-07-03 1998-10-20 The Cleveland Clinic Foundation Method of preparing a composite bone graft
US6049026A (en) * 1996-07-03 2000-04-11 The Cleveland Clinic Foundation Apparatus and methods for preparing an implantable graft
US5939039A (en) * 1997-01-16 1999-08-17 Orthovita, Inc. Methods for production of calcium phosphate

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9283074B2 (en) 2002-06-13 2016-03-15 Kensey Nash Bvf Technology, Llc Devices and methods for treating defects in the tissue of a living being

Also Published As

Publication number Publication date
AU2002241691A1 (en) 2002-05-27
WO2002040963A2 (en) 2002-05-23

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