SK140699A3 - Amidine derivatives, preparation method thereof, compositions containing them and their use for the treatment - Google Patents

Amidine derivatives, preparation method thereof, compositions containing them and their use for the treatment Download PDF

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Publication number
SK140699A3
SK140699A3 SK1406-99A SK140699A SK140699A3 SK 140699 A3 SK140699 A3 SK 140699A3 SK 140699 A SK140699 A SK 140699A SK 140699 A3 SK140699 A3 SK 140699A3
Authority
SK
Slovakia
Prior art keywords
formula
compound
pharmaceutically acceptable
condition
disease
Prior art date
Application number
SK1406-99A
Other languages
English (en)
Slovak (sk)
Inventor
James Macdonald
James Matz
William Shakespeare
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of SK140699A3 publication Critical patent/SK140699A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK1406-99A 1997-05-05 1998-04-28 Amidine derivatives, preparation method thereof, compositions containing them and their use for the treatment SK140699A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9701682A SE9701682D0 (sv) 1997-05-05 1997-05-05 Compounds
PCT/SE1998/000792 WO1998050380A1 (fr) 1997-05-05 1998-04-28 Composes

Publications (1)

Publication Number Publication Date
SK140699A3 true SK140699A3 (en) 2000-06-12

Family

ID=20406836

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1406-99A SK140699A3 (en) 1997-05-05 1998-04-28 Amidine derivatives, preparation method thereof, compositions containing them and their use for the treatment

Country Status (28)

Country Link
US (1) US6166030A (fr)
EP (1) EP0983266B1 (fr)
JP (1) JP2001523263A (fr)
KR (1) KR20010012227A (fr)
CN (1) CN1255130A (fr)
AR (1) AR012602A1 (fr)
AT (1) ATE210661T1 (fr)
AU (1) AU734394B2 (fr)
BR (1) BR9808725A (fr)
CA (1) CA2287999A1 (fr)
DE (1) DE69802923T2 (fr)
DK (1) DK0983266T3 (fr)
EE (1) EE9900475A (fr)
ES (1) ES2168757T3 (fr)
HU (1) HUP0003766A3 (fr)
ID (1) ID23156A (fr)
IL (1) IL132677A0 (fr)
IS (1) IS5237A (fr)
MX (1) MXPA99009874A (fr)
NO (1) NO995404L (fr)
NZ (1) NZ500676A (fr)
PL (1) PL336854A1 (fr)
PT (1) PT983266E (fr)
SE (1) SE9701682D0 (fr)
SK (1) SK140699A3 (fr)
TR (1) TR199902719T2 (fr)
WO (1) WO1998050380A1 (fr)
ZA (1) ZA983740B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001024826A2 (fr) * 1999-10-06 2001-04-12 The Brigham And Women's Hospital, Inc. Composes et procedes de modulation des effets non transcriptionnels des hormones steroides
US8852937B2 (en) * 2000-03-30 2014-10-07 Curis, Inc. Small organic molecule regulators of cell proliferation
US7115653B2 (en) * 2000-03-30 2006-10-03 Curis, Inc. Small organic molecule regulators of cell proliferation
US6683108B1 (en) * 2000-03-30 2004-01-27 Curis, Inc. Agonists of hedgehog signaling pathways and uses related thereto
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
KR20130136010A (ko) 2005-04-13 2013-12-11 네우렉슨 인코포레이티드 Ｎｏｓ 저해 활성을 갖는 치환된 인돌 화합물
US8173813B2 (en) * 2007-03-23 2012-05-08 Neuraxon, Inc. Quinolone and tetrahydroquinolone and related compounds having NOS inhibitory activity
NZ586082A (en) 2007-11-16 2013-03-28 Neuraxon Inc Indole compounds and methods for treating visceral pain

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09504278A (ja) * 1944-06-01 1997-04-28 ザ、ウェルカム、ファンデーション、リミテッド Ｎｏシンターゼインヒビターとしての置換尿素およびイソチオ尿素誘導体
DE69432019T2 (de) * 1993-08-12 2003-11-27 Astrazeneca Ab Amidin-derivate mit stickstoffoxid-synthease-aktivität
DE69416848T2 (de) * 1993-10-21 1999-07-08 Searle & Co Amidino-derivate als no-synthetase inhibitoren
ATE182889T1 (de) * 1994-05-07 1999-08-15 Astra Ab Bicyclische amidinderivate als no-synthetase inhibitoren
EE9700207A (et) * 1995-08-10 1998-02-16 Astra Aktiebolag Teraapias kasutatavad bitsüklilised amidiini derivaadid

Also Published As

Publication number Publication date
CA2287999A1 (fr) 1998-11-12
ATE210661T1 (de) 2001-12-15
NO995404L (no) 2000-01-05
CN1255130A (zh) 2000-05-31
ES2168757T3 (es) 2002-06-16
IL132677A0 (en) 2001-03-19
EP0983266A1 (fr) 2000-03-08
AR012602A1 (es) 2000-11-08
JP2001523263A (ja) 2001-11-20
ZA983740B (en) 1999-02-19
PT983266E (pt) 2002-05-31
BR9808725A (pt) 2000-07-11
IS5237A (is) 1999-11-01
PL336854A1 (en) 2000-07-17
US6166030A (en) 2000-12-26
MXPA99009874A (es) 2004-09-30
AU7460098A (en) 1998-11-27
NZ500676A (en) 2001-05-25
DE69802923T2 (de) 2002-07-04
TR199902719T2 (xx) 2000-02-21
KR20010012227A (ko) 2001-02-15
EP0983266B1 (fr) 2001-12-12
NO995404D0 (no) 1999-11-04
SE9701682D0 (sv) 1997-05-05
HUP0003766A3 (en) 2001-09-28
DK0983266T3 (da) 2002-03-11
ID23156A (id) 2000-03-23
DE69802923D1 (de) 2002-01-24
AU734394B2 (en) 2001-06-14
EE9900475A (et) 2000-06-15
HUP0003766A2 (en) 2001-03-28
WO1998050380A1 (fr) 1998-11-12

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