SK13272001A3 - Zlúčeniny a ich použitie pri liečbe astmy, alergie a zápalových porúch - Google Patents
Zlúčeniny a ich použitie pri liečbe astmy, alergie a zápalových porúch Download PDFInfo
- Publication number
- SK13272001A3 SK13272001A3 SK1327-2001A SK13272001A SK13272001A3 SK 13272001 A3 SK13272001 A3 SK 13272001A3 SK 13272001 A SK13272001 A SK 13272001A SK 13272001 A3 SK13272001 A3 SK 13272001A3
- Authority
- SK
- Slovakia
- Prior art keywords
- replaced
- alkylene
- methylenes
- alkynylene
- compound
- Prior art date
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- 238000000034 method Methods 0.000 title claims abstract description 13
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- 208000027866 inflammatory disease Diseases 0.000 title 1
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 claims abstract description 40
- 229960001340 histamine Drugs 0.000 claims abstract description 20
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- 231100000572 poisoning Toxicity 0.000 claims abstract description 8
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- -1 NR 3 C (O) R 4 Inorganic materials 0.000 claims description 80
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- JADMRVSHKZTLPH-UHFFFAOYSA-N phenyl n-hydroxycarbamate Chemical compound ONC(=O)OC1=CC=CC=C1 JADMRVSHKZTLPH-UHFFFAOYSA-N 0.000 description 1
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- KWGRBVOPPLSCSI-WCBMZHEXSA-N pseudoephedrine Chemical compound CN[C@@H](C)[C@@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WCBMZHEXSA-N 0.000 description 1
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- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
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- DLFVBJFMPXGRIB-UHFFFAOYSA-N thioacetamide Natural products CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 description 1
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- WBYWAXJHAXSJNI-VOTSOKGWSA-M trans-cinnamate Chemical compound [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 description 1
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- UNXRWKVEANCORM-UHFFFAOYSA-N triphosphoric acid Chemical class OP(O)(=O)OP(O)(=O)OP(O)(O)=O UNXRWKVEANCORM-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Application Number | Priority Date | Filing Date | Title |
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US12652199P | 1999-03-26 | 1999-03-26 | |
PCT/BE2000/000026 WO2000058295A2 (en) | 1999-03-26 | 2000-03-23 | Compounds and methods for treatment of asthma, allergy and inflammatory disorders |
Publications (1)
Publication Number | Publication Date |
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SK13272001A3 true SK13272001A3 (sk) | 2002-05-09 |
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SK1327-2001A SK13272001A3 (sk) | 1999-03-26 | 2000-03-23 | Zlúčeniny a ich použitie pri liečbe astmy, alergie a zápalových porúch |
Country Status (37)
Country | Link |
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US (3) | US6451801B1 (is) |
EP (1) | EP1165533B1 (is) |
JP (2) | JP2002540198A (is) |
KR (1) | KR20020005635A (is) |
CN (3) | CN1160344C (is) |
AR (2) | AR020026A1 (is) |
AT (1) | ATE279401T1 (is) |
AU (1) | AU761422B2 (is) |
BG (1) | BG105909A (is) |
BR (1) | BR0009341A (is) |
CA (1) | CA2368090A1 (is) |
CO (1) | CO5180543A1 (is) |
CZ (1) | CZ20013471A3 (is) |
DE (1) | DE60014876T2 (is) |
DZ (1) | DZ3027A1 (is) |
EE (2) | EE200400104A (is) |
ES (1) | ES2231164T3 (is) |
GT (1) | GT200000034A (is) |
HK (1) | HK1041880B (is) |
HU (1) | HUP0200613A2 (is) |
ID (1) | ID30430A (is) |
IL (1) | IL145481A0 (is) |
IS (2) | IS6077A (is) |
JO (1) | JO2250B1 (is) |
MX (1) | MXPA01009664A (is) |
NO (2) | NO20014648L (is) |
NZ (1) | NZ514291A (is) |
PA (1) | PA8493101A1 (is) |
PE (1) | PE20001566A1 (is) |
PL (1) | PL350845A1 (is) |
RU (1) | RU2241707C2 (is) |
SK (1) | SK13272001A3 (is) |
TR (2) | TR200102717T2 (is) |
UA (1) | UA69449C2 (is) |
WO (1) | WO2000058295A2 (is) |
YU (1) | YU68601A (is) |
ZA (1) | ZA200107642B (is) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
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PE20001566A1 (es) * | 1999-03-26 | 2001-02-05 | Ucb Sa | Piperazinas 1,4-sustituidas, piperidinas 1,4-sustituidas y 4-alquilidenilpiperidinas 1-sustituidas |
US6894059B1 (en) * | 1999-03-26 | 2005-05-17 | Ucb S.A. | Compounds and methods for treatment of asthma, allergy and inflammatory disorders |
US6686502B1 (en) * | 1999-03-26 | 2004-02-03 | Ucb S.A. | Compounds and methods for treatment of asthma, allergy and inflammatory disorders |
US6864219B2 (en) | 2000-01-17 | 2005-03-08 | Bayer Aktiengesellschaft | Substituted aryl ketones |
US6440994B1 (en) * | 2000-03-29 | 2002-08-27 | Richard J. Sanders, Jr. | Method of treating acne |
GB0009479D0 (en) * | 2000-04-17 | 2000-06-07 | Cipla Limited | Antihistaminic compounds |
JP4454314B2 (ja) | 2002-03-27 | 2010-04-21 | サン・ファーマ・アドバンスド・リサーチ・カンパニー・リミテッド | 4−(ジアリールメチル)−1−ピペラジニル誘導体 |
US7381821B2 (en) | 2003-01-23 | 2008-06-03 | Ucb, S.A. | Piperazine derivatives and their use as synthesis intermediates |
EP1457485A1 (en) * | 2003-03-14 | 2004-09-15 | Dompé S.P.A. | Sulfonic acids, their derivatives and pharmaceutical compositions containing them |
WO2006010283A1 (en) * | 2004-07-28 | 2006-02-02 | Universität Zürich | Prevention and treatment of thrombus formation |
KR100658436B1 (ko) * | 2005-12-09 | 2006-12-27 | 한국화학연구원 | 아데노실코발라민 함유 피부질환 치료용 외용제 조성물 |
US20090247634A1 (en) * | 2006-06-27 | 2009-10-01 | Hans-Erik Claesson | Methods for identifying modulators of eoxin formation |
NZ575624A (en) | 2006-10-18 | 2012-02-24 | Pfizer Prod Inc | Biaryl ether urea compounds |
ES2486299T3 (es) * | 2007-12-12 | 2014-08-18 | Amgen Inc. | Inhibidores del transportador de glicina 1 |
WO2009078444A1 (ja) * | 2007-12-18 | 2009-06-25 | Meiji Seika Kaisha, Ltd. | 炎症性腸疾患の予防または治療剤 |
WO2010046908A2 (en) | 2008-09-17 | 2010-04-29 | Calyx Chemicals And Pharmaceuticals Pvt. Ltd. | Novel water based process for the preparation of substituted diphenylmethyl piperazines |
CN102924406B (zh) * | 2012-11-07 | 2014-11-05 | 南京医科大学 | 取代芳氧乙基哌嗪类衍生物及其制备方法和应用 |
CN107602534B (zh) * | 2017-09-05 | 2020-04-24 | 合肥医工医药股份有限公司 | 具有抗组胺和抗炎活性的化合物及其制备方法和应用 |
CN115215800B (zh) * | 2021-04-21 | 2023-07-18 | 赣江中药创新中心 | 一种二苯并环基-环胺基醚衍生物或盐及其制备方法和应用 |
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US2898339A (en) | 1957-07-29 | 1959-08-04 | Wm S Merrell Co | N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine |
GB1574822A (en) | 1976-03-23 | 1980-09-10 | Lafon Labor | Acetohydroxamic acid derivatives and pharmaceutical compositions thereof |
US4282233B1 (en) * | 1980-06-19 | 2000-09-05 | Schering Corp | Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines |
DK154078C (da) * | 1981-02-06 | 1989-05-22 | Ucb Sa | Analogifremgangsmaade til fremstilling af 2-(2-(4-(diphenyl-methyl)-1-piperazinyl)ethoxy)-acetamider eller syreadditionssalte heraf |
US4826853A (en) | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
US5438062A (en) * | 1986-10-31 | 1995-08-01 | Schering Corporation | Benzo(5,6)cycloheptapyridines, compositions and methods of use |
US5066658A (en) * | 1988-11-10 | 1991-11-19 | Ortho Pharmaceutical Corporation | Substituted hydroxyureas |
US5288751A (en) * | 1992-11-06 | 1994-02-22 | Abbott Laboratories | [(Substituted) phenyalkyl]furylalkynyl-and [substituted) phenyalkyl] thienylalkynyl-N-hydroxyurea inhibitors or leukotriene biosynthesis |
DE69429438T2 (de) | 1993-10-15 | 2002-08-08 | Schering Corp., Kenilworth | Tricyclische carbamat-derivate zur inhibierung der g-protein funktion und für die behandlung von proliferativen erkrankungen |
US5719148A (en) | 1993-10-15 | 1998-02-17 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
WO1995013264A1 (fr) | 1993-11-08 | 1995-05-18 | Terumo Kabushiki Kaisha | Derive d'acide hydroxamique et preparation medicamenteuse contenant ledit derive |
US5877177A (en) | 1997-06-17 | 1999-03-02 | Schering Corporation | Carboxy piperidylacetamide tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
US6686502B1 (en) * | 1999-03-26 | 2004-02-03 | Ucb S.A. | Compounds and methods for treatment of asthma, allergy and inflammatory disorders |
PE20001566A1 (es) * | 1999-03-26 | 2001-02-05 | Ucb Sa | Piperazinas 1,4-sustituidas, piperidinas 1,4-sustituidas y 4-alquilidenilpiperidinas 1-sustituidas |
US6894059B1 (en) * | 1999-03-26 | 2005-05-17 | Ucb S.A. | Compounds and methods for treatment of asthma, allergy and inflammatory disorders |
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2000
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- 2000-03-23 WO PCT/BE2000/000026 patent/WO2000058295A2/en not_active Application Discontinuation
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- 2000-03-23 CN CNA2004100282269A patent/CN1528742A/zh active Pending
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- 2000-03-23 AT AT00912274T patent/ATE279401T1/de not_active IP Right Cessation
- 2000-03-23 KR KR1020017012282A patent/KR20020005635A/ko not_active Application Discontinuation
- 2000-03-23 CN CNA2004100495405A patent/CN1560041A/zh active Pending
- 2000-03-23 NZ NZ514291A patent/NZ514291A/en unknown
- 2000-03-23 TR TR2004/01779T patent/TR200401779T2/xx unknown
- 2000-03-23 PL PL00350845A patent/PL350845A1/xx not_active Application Discontinuation
- 2000-03-23 CA CA002368090A patent/CA2368090A1/en not_active Abandoned
- 2000-03-23 DE DE60014876T patent/DE60014876T2/de not_active Expired - Fee Related
- 2000-03-23 AR ARP000101298A patent/AR020026A1/es not_active Application Discontinuation
- 2000-03-23 UA UA2001107287A patent/UA69449C2/uk unknown
- 2000-03-23 BR BR0009341-6A patent/BR0009341A/pt not_active IP Right Cessation
- 2000-03-23 JP JP2000607998A patent/JP2002540198A/ja not_active Withdrawn
- 2000-03-23 EE EEP200100498A patent/EE200100498A/xx unknown
- 2000-03-23 SK SK1327-2001A patent/SK13272001A3/sk unknown
- 2000-03-23 EP EP00912274A patent/EP1165533B1/en not_active Expired - Lifetime
- 2000-03-23 YU YU68601A patent/YU68601A/sh unknown
- 2000-03-23 CZ CZ20013471A patent/CZ20013471A3/cs unknown
- 2000-03-23 RU RU2001129098/04A patent/RU2241707C2/ru not_active IP Right Cessation
- 2000-03-24 US US09/534,947 patent/US6451801B1/en not_active Expired - Fee Related
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- 2000-03-24 CO CO00021428A patent/CO5180543A1/es not_active Application Discontinuation
- 2000-03-25 DZ DZ000053A patent/DZ3027A1/xx active
- 2000-03-27 JO JO200026A patent/JO2250B1/en active
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2001
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- 2001-09-18 BG BG105909A patent/BG105909A/bg unknown
- 2001-09-25 NO NO20014648A patent/NO20014648L/no not_active Application Discontinuation
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2002
- 2002-05-11 HK HK02103566.6A patent/HK1041880B/zh not_active IP Right Cessation
- 2002-09-12 US US10/242,346 patent/US6797713B2/en not_active Expired - Fee Related
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2003
- 2003-08-08 US US10/637,163 patent/US20040048875A1/en not_active Abandoned
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2004
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- 2004-07-12 JP JP2004204939A patent/JP2005002118A/ja not_active Withdrawn
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