SK124294A3 - Tachykinin antagonist tricyclic compounds, preparation of same and pharmaceutical compositions containing such compounds - Google Patents

Tachykinin antagonist tricyclic compounds, preparation of same and pharmaceutical compositions containing such compounds Download PDF

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Publication number
SK124294A3
SK124294A3 SK1242-94A SK124294A SK124294A3 SK 124294 A3 SK124294 A3 SK 124294A3 SK 124294 A SK124294 A SK 124294A SK 124294 A3 SK124294 A3 SK 124294A3
Authority
SK
Slovakia
Prior art keywords
compounds
formula
substituents
group
acid
Prior art date
Application number
SK1242-94A
Other languages
English (en)
Slovak (sk)
Inventor
Vincenzo Pavone
Angelina Lombardi
Carlo Pedone
Carlo A Maggi
Laura Quartara
Original Assignee
Menarini Farma Ind
Guidotti & C Spa Labor
Malesci Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Farma Ind, Guidotti & C Spa Labor, Malesci Sas filed Critical Menarini Farma Ind
Publication of SK124294A3 publication Critical patent/SK124294A3/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/22Tachykinins, e.g. Eledoisins, Substance P; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SK1242-94A 1992-04-15 1993-04-13 Tachykinin antagonist tricyclic compounds, preparation of same and pharmaceutical compositions containing such compounds SK124294A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITFI920089A IT1262902B (it) 1992-04-15 1992-04-15 Composti triciclici antagonisti delle tachichinine, loro preparazione e loro uso in composizioni farmaceutiche.
PCT/EP1993/000893 WO1993021227A1 (en) 1992-04-15 1993-04-13 Tachykinin antagonist tricyclic compounds, preparation of same and pharmaceutical compositions containing such compounds

Publications (1)

Publication Number Publication Date
SK124294A3 true SK124294A3 (en) 1995-07-11

Family

ID=11350056

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1242-94A SK124294A3 (en) 1992-04-15 1993-04-13 Tachykinin antagonist tricyclic compounds, preparation of same and pharmaceutical compositions containing such compounds

Country Status (28)

Country Link
EP (1) EP0636146B1 (ko)
JP (1) JPH08500331A (ko)
KR (1) KR950700935A (ko)
CN (1) CN1039126C (ko)
AT (1) ATE156135T1 (ko)
AU (1) AU671118B2 (ko)
BG (1) BG99110A (ko)
BR (1) BR9306248A (ko)
CA (1) CA2118253A1 (ko)
CZ (1) CZ254294A3 (ko)
DE (1) DE69312698T2 (ko)
DK (1) DK0636146T3 (ko)
ES (1) ES2105265T3 (ko)
FI (1) FI944838A (ko)
GR (1) GR3024348T3 (ko)
HR (1) HRP930814A2 (ko)
HU (1) HUT70189A (ko)
IL (1) IL105381A (ko)
IT (1) IT1262902B (ko)
MX (1) MX9302161A (ko)
NO (1) NO943861L (ko)
NZ (1) NZ251969A (ko)
RO (1) RO112872B1 (ko)
RU (1) RU94045890A (ko)
SK (1) SK124294A3 (ko)
TW (1) TW234718B (ko)
WO (1) WO1993021227A1 (ko)
ZA (1) ZA932644B (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1277835B1 (it) * 1995-03-13 1997-11-12 Menarini Farma Ind Composti biciclici, loro preparazione ed uso in composizioni farmaceutiche
IT1283171B1 (it) * 1996-03-01 1998-04-16 Interdipartimentale Di Ricerca Composti solubili antagonisti delle tachichinine loro preparazione e loro uso in composizioni farmaceutiche
IT1291776B1 (it) 1997-02-07 1999-01-21 Menarini Ricerche Spa Composti monociclici a quattro residui bifunzionali, aventi azione nk-2 antagonista
IT1307809B1 (it) 1999-10-21 2001-11-19 Menarini Ricerche Spa Composti monociclici basici ad azione nk-2 antagonista, processi difabbricazione e formulazioni che li contengono.
EP1297826A1 (en) * 2001-09-27 2003-04-02 Menarini Ricerche S.p.A. Nasal pharmaceutical compositions containing a NK-2 antagonist

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8807246D0 (en) * 1988-03-25 1988-04-27 Merck Sharp & Dohme Therapeutic agents
DE3915361A1 (de) * 1989-05-11 1990-11-15 Merck Patent Gmbh Cyclopeptide

Also Published As

Publication number Publication date
HU9402977D0 (en) 1995-02-28
NZ251969A (en) 1997-12-19
CN1039126C (zh) 1998-07-15
NO943861D0 (no) 1994-10-13
BR9306248A (pt) 1998-06-23
EP0636146A1 (en) 1995-02-01
RU94045890A (ru) 1996-09-10
CA2118253A1 (en) 1993-10-28
ATE156135T1 (de) 1997-08-15
AU4039593A (en) 1993-11-18
FI944838A0 (fi) 1994-10-14
ES2105265T3 (es) 1997-10-16
JPH08500331A (ja) 1996-01-16
KR950700935A (ko) 1995-02-20
IT1262902B (it) 1996-07-22
ITFI920089A0 (it) 1992-04-15
WO1993021227A1 (en) 1993-10-28
AU671118B2 (en) 1996-08-15
ITFI920089A1 (it) 1993-10-15
NO943861L (no) 1994-10-13
GR3024348T3 (en) 1997-11-28
FI944838A (fi) 1994-10-14
MX9302161A (es) 1994-05-31
DK0636146T3 (da) 1998-02-23
RO112872B1 (ro) 1998-01-30
CZ254294A3 (en) 1995-07-12
ZA932644B (en) 1993-10-22
DE69312698D1 (de) 1997-09-04
EP0636146B1 (en) 1997-07-30
HUT70189A (en) 1995-09-28
HRP930814A2 (en) 1996-12-31
DE69312698T2 (de) 1997-12-04
CN1080916A (zh) 1994-01-19
IL105381A (en) 1998-02-22
BG99110A (bg) 1995-09-29
TW234718B (ko) 1994-11-21

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