SK12152001A3 - Derivát pyrazol-3-ónu ako faktor Xa inhibítorov, spôsob jeho prípravy, jeho použitie a farmaceutický prostriedok, ktorý ho obsahuje - Google Patents
Derivát pyrazol-3-ónu ako faktor Xa inhibítorov, spôsob jeho prípravy, jeho použitie a farmaceutický prostriedok, ktorý ho obsahuje Download PDFInfo
- Publication number
- SK12152001A3 SK12152001A3 SK1215-2001A SK12152001A SK12152001A3 SK 12152001 A3 SK12152001 A3 SK 12152001A3 SK 12152001 A SK12152001 A SK 12152001A SK 12152001 A3 SK12152001 A3 SK 12152001A3
- Authority
- SK
- Slovakia
- Prior art keywords
- group
- formula
- ylmethyl
- oxo
- isopropyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D231/08—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with oxygen or sulfur atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19909237A DE19909237A1 (de) | 1999-03-03 | 1999-03-03 | Pyrazol-3-on-derivate |
| PCT/EP2000/001695 WO2000051989A1 (de) | 1999-03-03 | 2000-02-29 | Pyrazol-3-on-derivate als faktor xa inhibitoren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK12152001A3 true SK12152001A3 (sk) | 2002-03-05 |
Family
ID=7899522
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1215-2001A SK12152001A3 (sk) | 1999-03-03 | 2000-02-29 | Derivát pyrazol-3-ónu ako faktor Xa inhibítorov, spôsob jeho prípravy, jeho použitie a farmaceutický prostriedok, ktorý ho obsahuje |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP1157010A1 (de) |
| JP (1) | JP2002538143A (de) |
| KR (1) | KR20010102428A (de) |
| CN (1) | CN1342148A (de) |
| AU (1) | AU2916500A (de) |
| BR (1) | BR0008608A (de) |
| CA (1) | CA2364908A1 (de) |
| CZ (1) | CZ20013164A3 (de) |
| DE (1) | DE19909237A1 (de) |
| HU (1) | HUP0200242A3 (de) |
| MX (1) | MXPA01008844A (de) |
| NO (1) | NO20014234L (de) |
| PL (1) | PL350941A1 (de) |
| RU (1) | RU2001126566A (de) |
| SK (1) | SK12152001A3 (de) |
| WO (1) | WO2000051989A1 (de) |
| ZA (1) | ZA200108064B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6455525B1 (en) | 1999-11-04 | 2002-09-24 | Cephalon, Inc. | Heterocyclic substituted pyrazolones |
| HUE025683T2 (hu) | 2002-12-03 | 2016-04-28 | Pharmacyclics Llc | VIIA faktor inhibitor 2-(2-hidroxi-bifenil-3-il)-1H-benzoimidazol-5-karboxamidin-származékok |
| JPWO2005012255A1 (ja) * | 2003-08-01 | 2006-09-14 | 三菱ウェルファーマ株式会社 | 炎症性関節疾患の治療剤 |
| DE102008020113A1 (de) | 2008-04-23 | 2009-10-29 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Dihydropyrazolone und ihre Verwendung |
| DE102005019712A1 (de) | 2005-04-28 | 2006-11-09 | Bayer Healthcare Ag | Dipyridyl-dihydropyrazolone und ihre Verwendung |
| DE102006050516A1 (de) | 2006-10-26 | 2008-04-30 | Bayer Healthcare Ag | Substituierte Dihydropyrazolone und ihre Verwendung |
| DE102006050513A1 (de) | 2006-10-26 | 2008-04-30 | Bayer Healthcare Ag | Substitiuierte Dihydropyrazolone und ihre Verwendung |
| DE102006050515A1 (de) | 2006-10-26 | 2008-04-30 | Bayer Healthcare Ag | Substituierte Dipyridiyl-dihydropyrazolone und ihre Verwendung |
| DE102007044032A1 (de) | 2007-09-14 | 2009-03-19 | Bayer Healthcare Ag | Substituierte heterocyclische Verbindungen und ihre Verwendung |
| DE102007048447A1 (de) | 2007-10-10 | 2009-04-16 | Bayer Healthcare Ag | Substituierte Dihydropyrazolthione und ihre Verwendung |
| DE102010044131A1 (de) | 2010-11-18 | 2012-05-24 | Bayer Schering Pharma Aktiengesellschaft | Substituiertes Natrium-1H-pyrazol-5-olat |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5612353A (en) * | 1995-06-07 | 1997-03-18 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds |
| JP3994453B2 (ja) * | 1995-10-13 | 2007-10-17 | 日産化学工業株式会社 | ピラゾロン類 |
-
1999
- 1999-03-03 DE DE19909237A patent/DE19909237A1/de not_active Withdrawn
-
2000
- 2000-02-29 KR KR1020017011000A patent/KR20010102428A/ko not_active Application Discontinuation
- 2000-02-29 SK SK1215-2001A patent/SK12152001A3/sk unknown
- 2000-02-29 PL PL00350941A patent/PL350941A1/xx unknown
- 2000-02-29 EP EP00907650A patent/EP1157010A1/de not_active Withdrawn
- 2000-02-29 RU RU2001126566/04A patent/RU2001126566A/ru unknown
- 2000-02-29 HU HU0200242A patent/HUP0200242A3/hu unknown
- 2000-02-29 CA CA002364908A patent/CA2364908A1/en not_active Abandoned
- 2000-02-29 WO PCT/EP2000/001695 patent/WO2000051989A1/de not_active Application Discontinuation
- 2000-02-29 JP JP2000602216A patent/JP2002538143A/ja active Pending
- 2000-02-29 CZ CZ20013164A patent/CZ20013164A3/cs unknown
- 2000-02-29 AU AU29165/00A patent/AU2916500A/en not_active Abandoned
- 2000-02-29 CN CN00804521A patent/CN1342148A/zh active Pending
- 2000-02-29 BR BR0008608-8A patent/BR0008608A/pt not_active Application Discontinuation
- 2000-02-29 MX MXPA01008844A patent/MXPA01008844A/es unknown
-
2001
- 2001-08-31 NO NO20014234A patent/NO20014234L/no not_active Application Discontinuation
- 2001-10-01 ZA ZA200108064A patent/ZA200108064B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000051989A1 (de) | 2000-09-08 |
| NO20014234L (no) | 2001-10-24 |
| AU2916500A (en) | 2000-09-21 |
| JP2002538143A (ja) | 2002-11-12 |
| HUP0200242A2 (hu) | 2002-11-28 |
| HUP0200242A3 (en) | 2002-12-28 |
| CA2364908A1 (en) | 2000-09-08 |
| CZ20013164A3 (cs) | 2001-12-12 |
| NO20014234D0 (no) | 2001-08-31 |
| BR0008608A (pt) | 2002-01-02 |
| MXPA01008844A (es) | 2002-05-14 |
| KR20010102428A (ko) | 2001-11-15 |
| CN1342148A (zh) | 2002-03-27 |
| ZA200108064B (en) | 2003-01-02 |
| EP1157010A1 (de) | 2001-11-28 |
| DE19909237A1 (de) | 2000-09-07 |
| PL350941A1 (en) | 2003-02-24 |
| RU2001126566A (ru) | 2004-02-27 |
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