SK1192002A3 - Caspase inhibitors and uses thereof - Google Patents
Caspase inhibitors and uses thereof Download PDFInfo
- Publication number
- SK1192002A3 SK1192002A3 SK119-2002A SK1192002A SK1192002A3 SK 1192002 A3 SK1192002 A3 SK 1192002A3 SK 1192002 A SK1192002 A SK 1192002A SK 1192002 A3 SK1192002 A3 SK 1192002A3
- Authority
- SK
- Slovakia
- Prior art keywords
- group
- optionally substituted
- nmr
- mhz
- dmso
- Prior art date
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
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- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
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- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
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- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20636200P | 2000-05-23 | 2000-05-23 | |
US21700600P | 2000-07-10 | 2000-07-10 | |
PCT/US2001/017075 WO2001090070A2 (en) | 2000-05-23 | 2001-05-23 | Caspase inhibitors and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SK1192002A3 true SK1192002A3 (en) | 2002-09-10 |
Family
ID=26901274
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK119-2002A SK1192002A3 (en) | 2000-05-23 | 2001-05-23 | Caspase inhibitors and uses thereof |
Country Status (16)
Country | Link |
---|---|
US (1) | US7053057B2 (es) |
EP (1) | EP1283827A2 (es) |
JP (1) | JP2003534325A (es) |
KR (1) | KR20020025959A (es) |
AP (1) | AP2002002407A0 (es) |
AR (1) | AR028619A1 (es) |
AU (1) | AU2001265008A1 (es) |
CA (1) | CA2380935A1 (es) |
MX (1) | MXPA02000823A (es) |
NO (1) | NO20020343L (es) |
NZ (1) | NZ516918A (es) |
PE (1) | PE20020058A1 (es) |
PL (1) | PL357713A1 (es) |
SK (1) | SK1192002A3 (es) |
TR (1) | TR200200767T1 (es) |
WO (1) | WO2001090070A2 (es) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60035037T2 (de) | 1999-04-09 | 2008-01-31 | Cytovia, Inc., San Diego | Caspase inhibitoren und ihre verwendung |
ATE266623T1 (de) | 1999-08-06 | 2004-05-15 | Vertex Pharma | Caspase inhibitoren und deren verwendung |
DE60040397D1 (de) | 1999-08-27 | 2008-11-13 | Cytovia Inc | Substituierte alpha-hydroxy-säuren als caspase-hemmer und ihre verwendung |
PE20011350A1 (es) | 2000-05-19 | 2002-01-15 | Vertex Pharma | PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE) |
WO2003024955A2 (en) | 2001-09-18 | 2003-03-27 | Sunesis Pharmaceuticals, Inc. | Small molecule inhibitors of caspases |
US7410956B2 (en) | 2002-02-11 | 2008-08-12 | Vertex Pharmaceuticals Incorporated | Caspase inhibitor prodrugs |
AU2003225088A1 (en) * | 2002-04-19 | 2003-11-03 | Vertex Pharmaceuticals Incorporated | Regulation of tnf-alpha |
US20060212020A1 (en) * | 2002-10-10 | 2006-09-21 | Lynne Rainen | Sample collection system with caspase inhibitor |
EP1626732B1 (en) * | 2003-05-22 | 2013-04-03 | CHIESI FARMACEUTICI S.p.A. | Means for preventing and treating cellular death and their biological applications |
AU2003902704A0 (en) * | 2003-05-29 | 2003-06-19 | Crc For Waste Management And Pollution Control Limited Of Unsw | Process for producing a nanoscale zero-valent metal |
RU2382780C2 (ru) | 2004-02-27 | 2010-02-27 | Вертекс Фармасьютикалз Инкорпорейтед | Ингибиторы каспаз и их применение |
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- 2001-05-23 TR TR2002/00767T patent/TR200200767T1/xx unknown
- 2001-05-23 AU AU2001265008A patent/AU2001265008A1/en not_active Abandoned
- 2001-05-23 US US09/863,649 patent/US7053057B2/en not_active Expired - Fee Related
- 2001-05-23 AP APAP/P/2002/002407A patent/AP2002002407A0/en unknown
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- 2001-05-23 PL PL01357713A patent/PL357713A1/xx not_active Application Discontinuation
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AR028619A1 (es) | 2003-05-14 |
TR200200767T1 (tr) | 2002-09-23 |
NZ516918A (en) | 2004-06-25 |
PL357713A1 (en) | 2004-07-26 |
WO2001090070A3 (en) | 2002-04-11 |
CA2380935A1 (en) | 2001-11-29 |
US7053057B2 (en) | 2006-05-30 |
NO20020343D0 (no) | 2002-01-22 |
WO2001090070A2 (en) | 2001-11-29 |
AP2002002407A0 (en) | 2002-03-31 |
MXPA02000823A (es) | 2002-07-30 |
US20020061853A1 (en) | 2002-05-23 |
NO20020343L (no) | 2002-03-21 |
AU2001265008A1 (en) | 2001-12-03 |
JP2003534325A (ja) | 2003-11-18 |
KR20020025959A (ko) | 2002-04-04 |
PE20020058A1 (es) | 2002-01-31 |
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