PT1796660T - Utilização de tricloro(dioxietileno-o,o¿)telurato de amónio (as101) para a inibição da enzima de conversão da interleucina-1 beta - Google Patents
Utilização de tricloro(dioxietileno-o,o¿)telurato de amónio (as101) para a inibição da enzima de conversão da interleucina-1 betaInfo
- Publication number
- PT1796660T PT1796660T PT57796393T PT05779639T PT1796660T PT 1796660 T PT1796660 T PT 1796660T PT 57796393 T PT57796393 T PT 57796393T PT 05779639 T PT05779639 T PT 05779639T PT 1796660 T PT1796660 T PT 1796660T
- Authority
- PT
- Portugal
- Prior art keywords
- 1beta
- inhibition
- dioxyethylene
- tellurate
- interleukin
- Prior art date
Links
- 102100035904 Caspase-1 Human genes 0.000 title abstract 3
- 108090000426 Caspase-1 Proteins 0.000 title abstract 3
- 230000005764 inhibitory process Effects 0.000 title abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 title 1
- XHGGEBRKUWZHEK-UHFFFAOYSA-L tellurate Chemical compound [O-][Te]([O-])(=O)=O XHGGEBRKUWZHEK-UHFFFAOYSA-L 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052714 tellurium Inorganic materials 0.000 abstract 1
- PORWMNRCUJJQNO-UHFFFAOYSA-N tellurium atom Chemical compound [Te] PORWMNRCUJJQNO-UHFFFAOYSA-N 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
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- A—HUMAN NECESSITIES
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- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C395/00—Compounds containing tellurium
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F11/00—Compounds containing elements of Groups 6 or 16 of the Periodic Table
- C07F11/005—Compounds containing elements of Groups 6 or 16 of the Periodic Table compounds without a metal-carbon linkage
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Biochemistry (AREA)
- Emergency Medicine (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61066004P | 2004-09-17 | 2004-09-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1796660T true PT1796660T (pt) | 2017-02-13 |
Family
ID=35985262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT57796393T PT1796660T (pt) | 2004-09-17 | 2005-09-15 | Utilização de tricloro(dioxietileno-o,o¿)telurato de amónio (as101) para a inibição da enzima de conversão da interleucina-1 beta |
Country Status (11)
| Country | Link |
|---|---|
| US (5) | US7709524B2 (pt) |
| EP (3) | EP1791535B1 (pt) |
| JP (1) | JP2008513439A (pt) |
| AT (1) | ATE402709T1 (pt) |
| AU (1) | AU2005283719A1 (pt) |
| CA (3) | CA2580642C (pt) |
| DE (1) | DE602005008622D1 (pt) |
| ES (2) | ES2312012T3 (pt) |
| HK (1) | HK1103355A1 (pt) |
| PT (1) | PT1796660T (pt) |
| WO (3) | WO2006030439A2 (pt) |
Families Citing this family (30)
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|---|---|---|---|---|
| WO2005060341A2 (en) | 2003-12-18 | 2005-07-07 | Biomas, Ltd | Tellurium derivatives for prevention and treatment of neurodegenerative processes |
| US9011933B2 (en) * | 2004-01-22 | 2015-04-21 | Biomas Ltd. | Therapeutic methods and pharmaceutical compositions for treating warts with tellurium compounds |
| US20080260770A1 (en) * | 2004-09-17 | 2008-10-23 | Biomas Ltd. | Use of Tellurium Compounds as Adjuvants |
| EP1791535B1 (en) | 2004-09-17 | 2008-07-30 | BioMAS Ltd. | Novel tellurium compounds and their use as immunomodulators |
| WO2006075314A2 (en) | 2005-01-11 | 2006-07-20 | Jemtex Ink Jet Printing Ltd. | Inkjet printer and method of controlling same |
| EP1924254A4 (en) * | 2005-09-15 | 2011-01-19 | Biomas Ltd | USE OF TELLURO COMPOUNDS FOR PROTECTION AGAINST ULTRAVIOLET RADIATION |
| NZ573248A (en) * | 2006-06-01 | 2011-01-28 | Nobera Pharma Sl | Use of allopurinol (1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one) for the treatment of palmar plantar erythrodysesthesia |
| EP1862166A1 (en) * | 2006-06-01 | 2007-12-05 | Yolanda Rodemer | Use of allopurinol for the treatment of palmar plantar erythrodysesthesia |
| JP2010502764A (ja) | 2006-09-11 | 2010-01-28 | バイオマス リミテッド | テルル含有化合物の局所製剤 |
| CA2705944C (en) | 2007-11-23 | 2017-10-24 | Biomas Ltd. | Methods and compositions for inhibiting integrins using tellurium-containing compounds |
| WO2009066301A2 (en) * | 2007-11-23 | 2009-05-28 | Biomas Ltd. | Methods and compositions for treating pox virus with tellurium-containing compounds |
| WO2010079488A1 (en) * | 2009-01-08 | 2010-07-15 | Biomas Ltd. | Tellurium-containing compounds for affecting male's fertility following chemotherapy and/or radiotherapy |
| WO2010079489A1 (en) * | 2009-01-08 | 2010-07-15 | Biomas Ltd. | Tellurium-containing compounds for affecting female's reproductive system following chemotherapy and/or radiotherapy |
| EP2246057A1 (en) | 2009-04-29 | 2010-11-03 | Nobera Pharma, S.L. | Use of allopurinol for the treatment of hand foot skin reaction |
| WO2010146547A1 (en) * | 2009-06-16 | 2010-12-23 | Biomas Ltd. | Tellurium-containing compounds for facilitating transplantation |
| WO2011041584A2 (en) | 2009-09-30 | 2011-04-07 | President And Fellows Of Harvard College | Methods for modulation of autophagy through the modulation of autophagy-enhancing gene products |
| WO2012065065A1 (en) * | 2010-11-12 | 2012-05-18 | Follica, Inc. | Methods and compositions for modulating hair growth, wound healing and scar revision |
| CA2819859A1 (en) | 2010-12-06 | 2012-06-14 | Follica, Inc. | Methods for treating baldness and promoting hair growth |
| US11000548B2 (en) | 2015-02-18 | 2021-05-11 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11318163B2 (en) | 2015-02-18 | 2022-05-03 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| US11596652B2 (en) | 2015-02-18 | 2023-03-07 | Enlivex Therapeutics R&D Ltd | Early apoptotic cells for use in treating sepsis |
| US11304976B2 (en) | 2015-02-18 | 2022-04-19 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| IL303543A (en) | 2015-02-18 | 2023-08-01 | Enlivex Therapeutics Rdo Ltd | Combined immunotherapy and cytokine control therapy for cancer treatment |
| US11497767B2 (en) | 2015-02-18 | 2022-11-15 | Enlivex Therapeutics R&D Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
| JP6803339B2 (ja) | 2015-04-21 | 2020-12-23 | エンリヴェックス セラピューティクス リミテッド | 治療用のプールされた血液アポトーシス細胞調製物及びそれらの使用 |
| KR20180110141A (ko) | 2016-02-18 | 2018-10-08 | 엔리벡스 테라퓨틱스 리미티드 | 암을 치료하기 위한 면역요법과 사이토카인 조절 요법의 조합 |
| WO2018199000A1 (ja) * | 2017-04-28 | 2018-11-01 | 国立大学法人京都大学 | 有機テルル化合物及びその製造方法、リビングラジカル重合開始剤、ビニル重合体の製造方法、並びにビニル重合体 |
| KR20240033119A (ko) | 2017-06-30 | 2024-03-12 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | 모발 성장을 조절하기 위한 조성물 및 방법 |
| CA3077359A1 (en) * | 2017-09-29 | 2019-04-04 | The Regents Of The University Of California | Compositions and methods for modulating hair growth |
| JP2021042161A (ja) * | 2019-09-11 | 2021-03-18 | 国立大学法人東海国立大学機構 | 脱毛剤、脱毛モデル動物及び白髪モデル動物 |
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| US4962207A (en) | 1985-09-30 | 1990-10-09 | Bar-Ilan University | Organic derivatives of tellurium and selenium |
| US5102908A (en) * | 1985-03-15 | 1992-04-07 | Michael Albeck | Method of treating Acquired Immunedeficiency Syndrome (AIDS) using organic tellurium and selenium derivatives |
| US4761490A (en) | 1985-03-15 | 1988-08-02 | Bar-Ilan University | Organic derivatives of tellurium and selenium and their use to stimulate cytokine production |
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| CA2380935A1 (en) * | 2000-05-23 | 2001-11-29 | Vertex Pharmaceuticals Incorporated | Caspase inhibitors and uses thereof |
| DE60131160T2 (de) * | 2000-06-07 | 2008-08-07 | Vertex Pharmaceuticals Inc., Cambridge | Caspase-inhibitoren und ihre verwendungen |
| US6747008B1 (en) * | 2000-06-19 | 2004-06-08 | University Of Southern California | Methods for treating and preventing alopecia |
| WO2001098325A1 (en) * | 2000-06-19 | 2001-12-27 | University Of Southern California | Methods for treating and preventing alopecia |
| WO2002042278A2 (en) * | 2000-11-21 | 2002-05-30 | Vertex Pharmaceuticals Incorporated | Imidazole and benzimidazole caspase inhibitors and uses thereof |
| US20030148970A1 (en) | 2001-01-12 | 2003-08-07 | Besterman Jeffrey M. | Methods for specifically inhibiting histone deacetylase-4 |
| CA2447999C (en) * | 2001-05-23 | 2011-04-26 | Vertex Pharmaceuticals Incorporated | Caspase inhibitors and uses thereof |
| US6472381B1 (en) * | 2001-10-12 | 2002-10-29 | Biomas Inc. | Method of treating psoriasis |
| IL146694A (en) * | 2001-11-22 | 2010-12-30 | Biomas Ltd | Use of an aqueous solution containing a biologically active complex of tellurium dioxide for manufacturing a medicament |
| AR040350A1 (es) * | 2002-06-28 | 2005-03-30 | Vertex Pharma | Inhibidores de caspasa y usos de los mismos |
| CA2511235A1 (en) * | 2002-12-20 | 2004-07-15 | Vertex Pharmaceuticals Incorporated | 4-oxo-3-(1-oxo-1h-isoquinolin-2-ylacetylamino)-pentanoic acid ester and amide derivatives and their use as caspase inhibitors |
| WO2005060341A2 (en) | 2003-12-18 | 2005-07-07 | Biomas, Ltd | Tellurium derivatives for prevention and treatment of neurodegenerative processes |
| US9474453B2 (en) | 2004-09-15 | 2016-10-25 | Itamar Medical Ltd. | Measuring blood flow and venous capacitance |
| US20080260770A1 (en) * | 2004-09-17 | 2008-10-23 | Biomas Ltd. | Use of Tellurium Compounds as Adjuvants |
| EP1791535B1 (en) * | 2004-09-17 | 2008-07-30 | BioMAS Ltd. | Novel tellurium compounds and their use as immunomodulators |
-
2005
- 2005-09-15 EP EP05779419A patent/EP1791535B1/en not_active Not-in-force
- 2005-09-15 WO PCT/IL2005/000991 patent/WO2006030439A2/en active Application Filing
- 2005-09-15 WO PCT/IL2005/000990 patent/WO2006030438A2/en active Application Filing
- 2005-09-15 US US11/663,032 patent/US7709524B2/en not_active Expired - Fee Related
- 2005-09-15 CA CA2580642A patent/CA2580642C/en not_active Expired - Fee Related
- 2005-09-15 EP EP05784166A patent/EP1802292A4/en not_active Withdrawn
- 2005-09-15 ES ES05779419T patent/ES2312012T3/es active Active
- 2005-09-15 US US11/663,031 patent/US7652065B2/en not_active Expired - Fee Related
- 2005-09-15 ES ES05779639.3T patent/ES2614113T3/es active Active
- 2005-09-15 CA CA2580643A patent/CA2580643C/en not_active Expired - Fee Related
- 2005-09-15 US US11/662,743 patent/US20090269418A1/en not_active Abandoned
- 2005-09-15 EP EP05779639.3A patent/EP1796660B1/en not_active Not-in-force
- 2005-09-15 WO PCT/IL2005/000989 patent/WO2006030437A2/en active IP Right Grant
- 2005-09-15 CA CA002580804A patent/CA2580804A1/en not_active Abandoned
- 2005-09-15 AT AT05779419T patent/ATE402709T1/de not_active IP Right Cessation
- 2005-09-15 JP JP2007531953A patent/JP2008513439A/ja active Pending
- 2005-09-15 DE DE602005008622T patent/DE602005008622D1/de active Active
- 2005-09-15 AU AU2005283719A patent/AU2005283719A1/en not_active Abandoned
- 2005-09-15 PT PT57796393T patent/PT1796660T/pt unknown
-
2007
- 2007-10-30 HK HK07111672.5A patent/HK1103355A1/xx not_active IP Right Cessation
-
2009
- 2009-12-02 US US12/629,071 patent/US20100081623A1/en not_active Abandoned
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2010
- 2010-03-22 US US12/728,362 patent/US8623908B2/en not_active Expired - Fee Related
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