SK108293A3 - Anti-tumor and anti-psoriatic agents - Google Patents

Anti-tumor and anti-psoriatic agents Download PDF

Info

Publication number
SK108293A3
SK108293A3 SK1082-93A SK108293A SK108293A3 SK 108293 A3 SK108293 A3 SK 108293A3 SK 108293 A SK108293 A SK 108293A SK 108293 A3 SK108293 A3 SK 108293A3
Authority
SK
Slovakia
Prior art keywords
compound
alkyl
formula
water
mixture
Prior art date
Application number
SK1082-93A
Other languages
English (en)
Slovak (sk)
Inventor
Stuart W Mccombie
Bandarpalle B Shankar
Michael Kirkup
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of SK108293A3 publication Critical patent/SK108293A3/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/044Pyrrole radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SK1082-93A 1991-04-11 1992-04-09 Anti-tumor and anti-psoriatic agents SK108293A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68377091A 1991-04-11 1991-04-11
PCT/US1992/002661 WO1992018507A1 (fr) 1991-04-11 1992-04-09 Agents antitumoraux et antipsoriasiques

Publications (1)

Publication Number Publication Date
SK108293A3 true SK108293A3 (en) 1994-09-07

Family

ID=24745378

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1082-93A SK108293A3 (en) 1991-04-11 1992-04-09 Anti-tumor and anti-psoriatic agents

Country Status (14)

Country Link
EP (2) EP0580812A1 (fr)
JP (1) JPH06503837A (fr)
CA (1) CA2108146A1 (fr)
CZ (1) CZ213693A3 (fr)
FI (1) FI934461A0 (fr)
HU (1) HUT70187A (fr)
IE (1) IE921148A1 (fr)
IL (1) IL101554A0 (fr)
MX (1) MX9201643A (fr)
NO (1) NO933611L (fr)
NZ (1) NZ242294A (fr)
SK (1) SK108293A3 (fr)
TW (1) TW214553B (fr)
WO (1) WO1992018507A1 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0575955B1 (fr) * 1992-06-22 1999-09-15 Kyowa Hakko Kogyo Co., Ltd. Procédé pour la préparation de dérivés de staurosporine
AU5100393A (en) * 1992-09-25 1994-04-26 Schering Corporation Diindolo compounds and pharmaceutical compositions containing them
US5624949A (en) * 1993-12-07 1997-04-29 Eli Lilly And Company Protein kinase C inhibitors
US5843935A (en) * 1993-12-07 1998-12-01 Eli Lilly And Company Protein kinase C inhibitors
CA2137203C (fr) * 1993-12-07 2006-11-28 William Francis Heath Jr. Inhibiteurs de la proteine kinase c
US5723456A (en) * 1993-12-07 1998-03-03 Eli Lilly & Company Therapeutic treatment for cardiovascular diseases
WO1995022331A1 (fr) * 1994-02-18 1995-08-24 Cephalon, Inc. Solutions aqueuses d'indolocarbazole
AU6657596A (en) * 1995-07-31 1997-02-26 Ciba-Geigy Ag Trindene compounds
US20040037828A1 (en) 2002-07-09 2004-02-26 Bar-Ilan University Methods and pharmaceutical compositions for healing wounds
FR2826653B1 (fr) * 2001-06-29 2005-10-14 Servier Lab Nouveaux derives de pyrido-pyrido-pyrrolo[3,2-g]pyrrolo [3,4-e]-indole et pyrido-pyrrolo[2,3-a]pyrrolo[3,4-c] carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
TW201041580A (en) 2001-09-27 2010-12-01 Alcon Inc Inhibitors of glycogen synthase kinase-3 (GSK-3) for treating glaucoma
ZA200601089B (en) 2003-08-07 2007-05-30 Hearlor Ltd Pharmaceutical compositions and methods for accelerating wound healing
ZA200802546B (en) 2005-08-29 2009-10-28 Healor Ltd Methods and compositions for prvention and treatment of diabetic and aged skin
EP2181999A1 (fr) 2008-11-03 2010-05-05 Zentiva, A.S. Procédé de fabrication d'un ruboxistaurine
JP2013516500A (ja) 2010-01-11 2013-05-13 ヒールオア・リミテッド 炎症性疾患および障害を治療するための方法
JP2017524739A (ja) 2014-07-17 2017-08-31 アンセルムInserm 神経筋接合部関連疾患の処置方法
WO2016207366A1 (fr) 2015-06-26 2016-12-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Méthodes et compositions pharmaceutiques de traitement d'infections virales

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923986A (en) * 1987-03-09 1990-05-08 Kyowa Hakko Kogyo Co., Ltd. Derivatives of physiologically active substance K-252
DE3924538A1 (de) * 1989-07-25 1991-01-31 Goedecke Ag Indolocarbazol und dessen verwendung

Also Published As

Publication number Publication date
FI934461A (fi) 1993-10-11
TW214553B (fr) 1993-10-11
EP0508792A1 (fr) 1992-10-14
AU646163B2 (en) 1994-02-10
AU1798292A (en) 1992-11-17
NO933611D0 (no) 1993-10-08
CZ213693A3 (en) 1994-05-18
IE921148A1 (en) 1992-10-21
WO1992018507A1 (fr) 1992-10-29
NO933611L (no) 1993-10-08
CA2108146A1 (fr) 1992-10-12
JPH06503837A (ja) 1994-04-28
EP0580812A1 (fr) 1994-02-02
IL101554A0 (en) 1992-12-30
HUT70187A (en) 1995-09-28
MX9201643A (es) 1992-10-01
FI934461A0 (fi) 1993-10-11
NZ242294A (en) 1993-07-27
HU9302869D0 (en) 1993-12-28

Similar Documents

Publication Publication Date Title
SK108293A3 (en) Anti-tumor and anti-psoriatic agents
DE68910421T2 (de) DC-88A-Derivate.
US4981968A (en) Synthesis of camptothecin and analogs thereof
AU757510C (en) Pyrrolobenzodiazepines
KR100312445B1 (ko) 트리플루오로메틸피롤로인돌카르복실산 에스테르 유도체의 제조방법
US5122526A (en) Camptothecin and analogs thereof and pharmaceutical compositions and method using them
EP3919488A1 (fr) Immunomodulateur
KR100189043B1 (ko) 갈란타민 유도체 및 이를 함유하는 약제학적 조성물
RU2129546C1 (ru) 6,9-бис(аминозамещенные)-бензо(g)изохинолин-5,10-дионы, способ их получения, фармацевтическая композиция на их основе и способ ингибирования опухолей у млекопитающих
JPH08506356A (ja) 抗癌遺伝子剤および抗癌剤としてのアンサマイシン誘導体
CA2082820C (fr) Derives 6-aminooctahydroindolizinetriol
PL175707B1 (pl) Nowe estry 1-aryloksy-3-alkiloamino-2-propanolu
RU2200737C2 (ru) Пиримидо[4,5-b]индолы и промежуточное соединение (варианты)
US5519029A (en) 2-aminoalkyl-5-aminoalkylamino substituted-isoquinoindazole-6(2H)-ones
JPH08509740A (ja) カンプトテシンの水溶性誘導体
EP0662076B1 (fr) Isoquinoindazole-6-(2h)-ones a substitution 2-aminoalkyle-5-aminoalkylamino, a activite antitumorale
HU203886B (en) Process for producing 12-halogeno-forscholine derivatives and pharmaceutical compositions contining them as active components
AU646163C (en) Anti-tumor and anti-psoriatic agents
KR100390767B1 (ko) 아지리디닐퀴놀린디온 유도체와 그의 제조방법
AU767089B2 (en) Process to prepare (5R)-(methylamino)-5,6-dihydro-4H- imidazo(4,5,1-ij)-quinolin-2(1H)-one
US5604246A (en) 2-aminoalkyl-5-aminoalkylamino substituted-isoquinoindazole-6(2H)-ones
RU2154066C2 (ru) Бензотиопираноиндазолы, фармацевтическая композиция на их основе и способ лечения опухоли
WO1995024407A1 (fr) Indazoles hetero-anneles
JP2003506376A (ja) 1,2−ジヒドロ−1−オキソ−ピラジノ[1,2−a]インドール誘導体
CZ286654B6 (cs) 2-/2-/(2-hydroxyethyl) amino/ethyl/-5-//(2-methylamino)ethyl/amino/indazol/4,3-gh/isochinolin-6(2H) on, způsob jeho výroby a farmaceutický prostředek s jeho obsahem