SI9500250A - Dna sequences encoding novel biosynthetic insulin precursors and process for preparation of insulin. - Google Patents

Dna sequences encoding novel biosynthetic insulin precursors and process for preparation of insulin. Download PDF

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Publication number
SI9500250A
SI9500250A SI9500250A SI9500250A SI9500250A SI 9500250 A SI9500250 A SI 9500250A SI 9500250 A SI9500250 A SI 9500250A SI 9500250 A SI9500250 A SI 9500250A SI 9500250 A SI9500250 A SI 9500250A
Authority
SI
Slovenia
Prior art keywords
insulin
transformed
dna sequence
cells
gene
Prior art date
Application number
SI9500250A
Other languages
English (en)
Slovenian (sl)
Inventor
Silvija Mestric
Peter J Punt
Radovan Valinger
Den Hondel Cees A M J J Van
Original Assignee
Pliva Pharm & Chem Works
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Pharm & Chem Works filed Critical Pliva Pharm & Chem Works
Publication of SI9500250A publication Critical patent/SI9500250A/sl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SI9500250A 1994-08-05 1995-08-04 Dna sequences encoding novel biosynthetic insulin precursors and process for preparation of insulin. SI9500250A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HR940432A HRP940432B1 (en) 1994-08-05 1994-08-05 Dna sequences encoding biosynthetic insulin precursors and process for preparation of insulin

Publications (1)

Publication Number Publication Date
SI9500250A true SI9500250A (en) 1996-02-29

Family

ID=10946142

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9500250A SI9500250A (en) 1994-08-05 1995-08-04 Dna sequences encoding novel biosynthetic insulin precursors and process for preparation of insulin.

Country Status (13)

Country Link
EP (1) EP0704527B1 (pt)
CN (1) CN1126761A (pt)
AT (1) ATE239791T1 (pt)
BG (1) BG62336B1 (pt)
CA (1) CA2155451A1 (pt)
CZ (1) CZ199995A3 (pt)
DE (1) DE69530647T2 (pt)
ES (1) ES2198428T3 (pt)
HR (1) HRP940432B1 (pt)
PL (1) PL309882A1 (pt)
PT (1) PT704527E (pt)
SI (1) SI9500250A (pt)
SK (1) SK97195A3 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9513967D0 (en) * 1995-07-08 1995-09-06 Univ Leicester Insulin
AU5504999A (en) * 1998-07-20 2000-02-14 Frenken, Leon Gerardus Joseph Production of proteins
DE60016560T2 (de) 1999-01-06 2005-12-15 Genentech, Inc., South San Francisco Mutierte variante des insulin-ähnlichen wachstumsfaktor-i (igf-i)
JP3406244B2 (ja) * 1999-04-30 2003-05-12 伊藤ハム株式会社 新規な融合蛋白質からの組み換えインスリンの製造方法
DE19947456A1 (de) 1999-10-02 2001-04-05 Aventis Pharma Gmbh C-Peptid zur verbesserten Herstellung von Insulin und Insulinanaloga
DE60120372T2 (de) 2000-03-24 2007-07-05 Genentech Inc., San Francisco Verwendung von insulin zur behandlung von knorpelkrankheiten
AU2002316807A1 (en) * 2001-06-08 2002-12-23 Novo Nordisk A/S Method for making insulin precursors and insulin precursor analogs
EP2598527A4 (en) * 2010-07-28 2014-01-08 Smartcells Inc RECOMBINANT EXPRESSED INSULIN POLYPEPTIDES AND APPLICATIONS THEREOF
AR087433A1 (es) * 2011-08-08 2014-03-26 Merck Sharp & Dohme Analogos de insulina n-glicosilados

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE63757T1 (de) * 1985-03-28 1991-06-15 Chiron Corp Expression durch verwendung von fusionsgenen fuer proteinproduktion.
FI872102A (fi) * 1986-06-06 1987-12-07 Panlabs Inc Expressionssystem hos filamentala fungi.
CA1340772C (en) * 1987-12-30 1999-09-28 Patricia Tekamp-Olson Expression and secretion of heterologous protiens in yeast employing truncated alpha-factor leader sequences
DK300090D0 (da) * 1990-12-19 1990-12-19 Novo Nordisk As Fremgangsmaade til fremstilling af leadersekvenser
BR9400600A (pt) * 1994-02-17 1995-10-24 Finep Financiadora De Estudos Processos para produção de uma protéina recombinante e/ou de glicosilfosfatidilinositol (GPI) em células de microorganismos eucariontes e para a obtenção de leveduras de S. cerevisae; célula de levedura sequência de nucleotídios; meio de cultura; medicamento ou vacina; e produto dos ditos processos

Also Published As

Publication number Publication date
ES2198428T3 (es) 2004-02-01
EP0704527B1 (en) 2003-05-07
BG99844A (bg) 1996-02-28
EP0704527A3 (en) 1997-08-27
SK97195A3 (en) 1996-02-07
CN1126761A (zh) 1996-07-17
DE69530647T2 (de) 2004-03-11
ATE239791T1 (de) 2003-05-15
HRP940432B1 (en) 2003-10-31
HRP940432A2 (en) 1997-08-31
BG62336B1 (bg) 1999-08-31
DE69530647D1 (de) 2003-06-12
CZ199995A3 (en) 1996-02-14
PT704527E (pt) 2003-09-30
PL309882A1 (en) 1996-02-19
EP0704527A2 (en) 1996-04-03
CA2155451A1 (en) 1996-02-06

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