SI3127604T1 - Postopek za pripravo dipeptidnih derivatov lizina in glutaminske kisline - Google Patents
Postopek za pripravo dipeptidnih derivatov lizina in glutaminske kislineInfo
- Publication number
- SI3127604T1 SI3127604T1 SI201331208T SI201331208T SI3127604T1 SI 3127604 T1 SI3127604 T1 SI 3127604T1 SI 201331208 T SI201331208 T SI 201331208T SI 201331208 T SI201331208 T SI 201331208T SI 3127604 T1 SI3127604 T1 SI 3127604T1
- Authority
- SI
- Slovenia
- Prior art keywords
- lysin
- preparation
- glutamic acid
- dipeptide derivatives
- acid dipeptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/32—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C271/34—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12168119.1A EP2664374A1 (en) | 2012-05-15 | 2012-05-15 | Lysin-glutamic acid dipeptide derivatives |
| EP16179885.5A EP3127604B1 (en) | 2012-05-15 | 2013-05-13 | Process for the preparation of lysin-glutamic acid dipeptide derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI3127604T1 true SI3127604T1 (sl) | 2018-11-30 |
Family
ID=48430764
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201331208T SI3127604T1 (sl) | 2012-05-15 | 2013-05-13 | Postopek za pripravo dipeptidnih derivatov lizina in glutaminske kisline |
| SI201330739T SI2849882T1 (sl) | 2012-05-15 | 2013-05-13 | Dipeptidni derivati lizin-glutaminske kisline |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201330739T SI2849882T1 (sl) | 2012-05-15 | 2013-05-13 | Dipeptidni derivati lizin-glutaminske kisline |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US9522874B2 (sl) |
| EP (3) | EP2664374A1 (sl) |
| JP (1) | JP6162795B2 (sl) |
| KR (2) | KR102094928B1 (sl) |
| CN (1) | CN104271227B (sl) |
| AR (1) | AR091044A1 (sl) |
| AU (1) | AU2013261894B2 (sl) |
| BR (1) | BR112014028334B1 (sl) |
| CA (2) | CA3096624C (sl) |
| ES (2) | ES2637415T3 (sl) |
| HK (1) | HK1200753A1 (sl) |
| HR (2) | HRP20171058T1 (sl) |
| IL (1) | IL235425B (sl) |
| MX (2) | MX349822B (sl) |
| MY (2) | MY184184A (sl) |
| NZ (1) | NZ631215A (sl) |
| PL (2) | PL3127604T3 (sl) |
| RU (1) | RU2640812C2 (sl) |
| SG (1) | SG11201406888QA (sl) |
| SI (2) | SI3127604T1 (sl) |
| WO (1) | WO2013171135A1 (sl) |
| ZA (1) | ZA201407528B (sl) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| EP2934569A1 (en) | 2012-12-21 | 2015-10-28 | Sanofi | Exendin-4 derivatives |
| GB201315335D0 (en) | 2013-08-29 | 2013-10-09 | Of Singapore | Amino diacids containing peptide modifiers |
| EP3080152A1 (en) | 2013-12-13 | 2016-10-19 | Sanofi | Non-acylated exendin-4 peptide analogues |
| WO2015086733A1 (en) | 2013-12-13 | 2015-06-18 | Sanofi | Dual glp-1/glucagon receptor agonists |
| TW201609795A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 作為雙重ｇｌｐ－１／ｇｉｐ受體促效劑的艾塞那肽－４（ｅｘｅｎｄｉｎ－４）胜肽類似物 |
| TW201609799A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 雙重ｇｌｐ－１／ｇｉｐ受體促效劑 |
| TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑 |
| TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自ｅｘｅｎｄｉｎ－４之雙重ｇｌｐ－１／升糖素受體促效劑 |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物 |
| US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
| AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
| TW201706291A (zh) | 2015-07-10 | 2017-02-16 | 賽諾菲公司 | 作為選擇性肽雙重ｇｌｐ－１／升糖素受體促效劑之新毒蜥外泌肽（ｅｘｅｎｄｉｎ－４）衍生物 |
| CN109641946A (zh) | 2016-03-23 | 2019-04-16 | 巴切姆股份公司 | 胰高血糖素样肽的制备方法 |
| WO2020208409A1 (en) * | 2019-04-10 | 2020-10-15 | Dr. Reddy’S Laboratories Limited | Improved processes for the preparation of peptide intermediates/modifiers |
| CN111454180A (zh) * | 2020-04-10 | 2020-07-28 | 大连阿拉宁生物技术有限公司 | 一种索马鲁肽侧链中间体及其制备方法 |
| CN113004370B (zh) * | 2021-02-09 | 2022-06-17 | 宁波绿之健药业有限公司 | 一种具有缓解高尿酸血症和调节肠道菌群的二肽及其应用 |
| EP4345104A1 (en) | 2022-09-30 | 2024-04-03 | Bachem Holding AG | Method for preparing liraglutide |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE122009000079I2 (de) * | 1996-08-30 | 2011-06-16 | Novo Nordisk As Novo Alle | Glp-1 derivate |
| WO2001066135A1 (en) * | 2000-03-08 | 2001-09-13 | Novo Nordisk A/S | Lowering serum lipids |
| US20060258580A1 (en) * | 2003-05-14 | 2006-11-16 | Regents Of The University Of Michigan | Modulators of Nod1 signaling |
| JP2006233405A (ja) * | 2005-08-16 | 2006-09-07 | Asahi Kasei Chemicals Corp | 繊維処理剤 |
| IE20060841A1 (en) * | 2006-11-21 | 2008-05-28 | Ipsen Mfg Ireland Ltd | Boc and fmoc solid phase peptide synthesis |
| JP2008290987A (ja) * | 2007-05-28 | 2008-12-04 | Shiseido Co Ltd | Ｃｍｃ修復剤、毛髪化粧料およびｃｍｃ修復方法 |
| JP5127316B2 (ja) * | 2007-06-22 | 2013-01-23 | 旭化成ケミカルズ株式会社 | 化学機械研磨用組成物 |
| AU2008365555B2 (en) * | 2008-12-15 | 2016-01-14 | Zealand Pharma A/S | Glucagon analogues |
| ME02220B (me) * | 2009-07-13 | 2016-02-20 | Zealand Pharma As | Analozi acilovanog glukagona |
| JP2011057663A (ja) * | 2009-08-11 | 2011-03-24 | Sumitomo Chemical Co Ltd | 化合物及びフォトレジスト組成物 |
| CN102286092B (zh) * | 2011-09-14 | 2014-01-01 | 深圳翰宇药业股份有限公司 | 利拉鲁肽的固相合成方法 |
| CN104144696A (zh) * | 2011-12-23 | 2014-11-12 | 西兰制药公司 | 胰高血糖素类似物 |
-
2012
- 2012-05-15 EP EP12168119.1A patent/EP2664374A1/en not_active Ceased
-
2013
- 2013-05-13 ES ES13722408.5T patent/ES2637415T3/es active Active
- 2013-05-13 AU AU2013261894A patent/AU2013261894B2/en active Active
- 2013-05-13 CA CA3096624A patent/CA3096624C/en active Active
- 2013-05-13 KR KR1020197014335A patent/KR102094928B1/ko active IP Right Grant
- 2013-05-13 CA CA2868144A patent/CA2868144C/en active Active
- 2013-05-13 SI SI201331208T patent/SI3127604T1/sl unknown
- 2013-05-13 PL PL16179885T patent/PL3127604T3/pl unknown
- 2013-05-13 SG SG11201406888QA patent/SG11201406888QA/en unknown
- 2013-05-13 NZ NZ631215A patent/NZ631215A/en unknown
- 2013-05-13 MY MYPI2018000443A patent/MY184184A/en unknown
- 2013-05-13 CN CN201380024470.5A patent/CN104271227B/zh active Active
- 2013-05-13 BR BR112014028334-6A patent/BR112014028334B1/pt active IP Right Grant
- 2013-05-13 MX MX2014013505A patent/MX349822B/es active IP Right Grant
- 2013-05-13 EP EP13722408.5A patent/EP2849882B1/en active Active
- 2013-05-13 KR KR1020147031824A patent/KR102018160B1/ko active IP Right Grant
- 2013-05-13 PL PL13722408T patent/PL2849882T3/pl unknown
- 2013-05-13 RU RU2014148530A patent/RU2640812C2/ru active
- 2013-05-13 MX MX2017006522A patent/MX363728B/es unknown
- 2013-05-13 MY MYPI2014703386A patent/MY172395A/en unknown
- 2013-05-13 SI SI201330739T patent/SI2849882T1/sl unknown
- 2013-05-13 WO PCT/EP2013/059759 patent/WO2013171135A1/en active Application Filing
- 2013-05-13 JP JP2015512007A patent/JP6162795B2/ja active Active
- 2013-05-13 ES ES16179885.5T patent/ES2692364T3/es active Active
- 2013-05-13 EP EP16179885.5A patent/EP3127604B1/en active Active
- 2013-05-14 AR ARP130101662A patent/AR091044A1/es active IP Right Grant
-
2014
- 2014-10-16 ZA ZA2014/07528A patent/ZA201407528B/en unknown
- 2014-10-30 IL IL235425A patent/IL235425B/en active IP Right Grant
- 2014-11-12 US US14/539,126 patent/US9522874B2/en active Active
-
2015
- 2015-02-05 HK HK15101247.2A patent/HK1200753A1/xx unknown
-
2016
- 2016-11-10 US US15/348,093 patent/US9802886B2/en active Active
-
2017
- 2017-07-11 HR HRP20171058TT patent/HRP20171058T1/hr unknown
- 2017-10-11 US US15/730,585 patent/US20180029978A1/en not_active Abandoned
-
2018
- 2018-10-17 HR HRP20181696TT patent/HRP20181696T1/hr unknown
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