SI2865663T1 - Novi derivati indansulfamida - Google Patents

Novi derivati indansulfamida

Info

Publication number
SI2865663T1
SI2865663T1 SI201330677A SI201330677A SI2865663T1 SI 2865663 T1 SI2865663 T1 SI 2865663T1 SI 201330677 A SI201330677 A SI 201330677A SI 201330677 A SI201330677 A SI 201330677A SI 2865663 T1 SI2865663 T1 SI 2865663T1
Authority
SI
Slovenia
Prior art keywords
novel
derivative
indanesulfamide derivative
novel indanesulfamide
indanesulfamide
Prior art date
Application number
SI201330677A
Other languages
English (en)
Inventor
Yuji Kazuta
Toru Watanabe
Keiichi Sorimachi
Minako Saito
Yoichi Kita
Toshiaki Tanaka
Hiroyuki Higashiyama
Takahisa Hanada
Tetsuyuki Teramoto
Takashi Kosasa
Yukio Ishikawa
Original Assignee
Eisai R&D Management Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Management Co., Ltd. filed Critical Eisai R&D Management Co., Ltd.
Publication of SI2865663T1 publication Critical patent/SI2865663T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/04Diamides of sulfuric acids
    • C07C307/08Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • A61K31/277Nitriles; Isonitriles having a ring, e.g. verapamil
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI201330677A 2012-06-21 2013-06-17 Novi derivati indansulfamida SI2865663T1 (sl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261662626P 2012-06-21 2012-06-21
US201261709737P 2012-10-04 2012-10-04
US201361751331P 2013-01-11 2013-01-11
EP13807707.8A EP2865663B1 (en) 2012-06-21 2013-06-17 Novel indanesulfamide derivative
PCT/JP2013/066623 WO2013191144A1 (ja) 2012-06-21 2013-06-17 新規インダンスルファミド誘導体

Publications (1)

Publication Number Publication Date
SI2865663T1 true SI2865663T1 (sl) 2017-07-31

Family

ID=49768740

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201330677A SI2865663T1 (sl) 2012-06-21 2013-06-17 Novi derivati indansulfamida

Country Status (34)

Country Link
US (1) US9018260B2 (sl)
EP (1) EP2865663B1 (sl)
JP (1) JP5883135B2 (sl)
KR (1) KR101951519B1 (sl)
CN (1) CN104395285B (sl)
AR (1) AR091506A1 (sl)
AU (1) AU2013278450B2 (sl)
BR (1) BR112014031565B1 (sl)
CA (1) CA2877097C (sl)
CL (1) CL2014003429A1 (sl)
CY (1) CY1119171T1 (sl)
DK (1) DK2865663T3 (sl)
ES (1) ES2628374T3 (sl)
HK (1) HK1207363A1 (sl)
HR (1) HRP20170863T1 (sl)
HU (1) HUE033583T2 (sl)
IL (1) IL236295A (sl)
JO (1) JO3263B1 (sl)
LT (1) LT2865663T (sl)
ME (1) ME02753B (sl)
MX (1) MX355261B (sl)
MY (1) MY169073A (sl)
NZ (1) NZ702974A (sl)
PE (1) PE20150284A1 (sl)
PH (1) PH12014502805B1 (sl)
PL (1) PL2865663T3 (sl)
PT (1) PT2865663T (sl)
RS (1) RS56073B1 (sl)
RU (1) RU2619937C2 (sl)
SG (1) SG11201408359PA (sl)
SI (1) SI2865663T1 (sl)
TW (1) TWI597263B (sl)
WO (1) WO2013191144A1 (sl)
ZA (1) ZA201409248B (sl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2919397C (en) 2013-09-09 2021-05-18 Peloton Therapeutics, Inc. Aryl ethers as hif-2.alpha. inhibitors for the treatment of cancer
EP3083639B1 (en) 2013-12-16 2019-05-29 Peloton Therapeutics, Inc. Cyclic sulfone and sulfoximine analogs and uses thereof
ES2673876T3 (es) * 2013-12-19 2018-06-26 Eisai R&D Management Co., Ltd. Agente terapéutico y/o preventivo que comprende un derivado de 1-indansulfamida para el dolor
EP3267792A4 (en) 2015-03-11 2018-09-26 Peloton Therapeutics, Inc. Compositions for use in treating pulmonary arterial hypertension
WO2016145045A1 (en) 2015-03-11 2016-09-15 Peloton Therapeutics, Inc. Compositions for use in treating glioblastoma
WO2016144826A1 (en) 2015-03-11 2016-09-15 Peloton Therapeutics, Inc. Substituted pyridines and uses thereof
US10807948B2 (en) 2015-03-11 2020-10-20 Peloton Therapeutics, Inc. Aromatic compounds and uses thereof
WO2016168510A1 (en) 2015-04-17 2016-10-20 Peloton Therapeutics, Inc. Combination therapy of a hif-2-alpha inhibitor and an immunotherapeutic agent and uses thereof
US9796697B2 (en) 2015-06-12 2017-10-24 Peloton Therapeutics, Inc. Tricyclic inhibitors of HIF-2-alpha and uses thereof
JP7265526B2 (ja) 2018-03-20 2023-04-26 エーザイ・アール・アンド・ディー・マネジメント株式会社 てんかん治療剤
JP2024026905A (ja) * 2020-11-25 2024-02-29 エーザイ・アール・アンド・ディー・マネジメント株式会社 てんかん治療剤
WO2023210617A1 (ja) * 2022-04-27 2023-11-02 エーザイ・アール・アンド・ディー・マネジメント株式会社 パーキンソン病治療用医薬組成物

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3383414A (en) 1964-08-26 1968-05-14 Sandoz Ag Benzocycloalkyl sulfamides
US3709677A (en) 1969-06-25 1973-01-09 Sandoz Ag N-substituted sulfamoyl compounds useful as herbicides
EP1401805A1 (en) * 2001-06-26 2004-03-31 Yissum Research Development Company Of The Hebrew University Of Jerusalem Valproyltaurinamide derivatives as anticonvulsant and cns active agents
TW200307539A (en) 2002-02-01 2003-12-16 Bristol Myers Squibb Co Cycloalkyl inhibitors of potassium channel function
BRPI0514278A (pt) * 2004-08-24 2008-06-10 Janssen Pharmaceutica Nv derivados de sulfamida de heteroarila benzo-fundida úteis como agentes anti-convulsivante
US20070155823A1 (en) * 2005-12-19 2007-07-05 Smith-Swintosky Virginia L Use of benzo-fused heterocycle sulfamide derivatives as neuroprotective agents
CN100572365C (zh) * 2006-01-26 2009-12-23 全哲山 用作抗癫痫药的1,2,4-三唑并[4,3-a]喹啉-1-酮衍生物及其可药用盐
JP2009184924A (ja) 2006-05-31 2009-08-20 Eisai R & D Management Co Ltd 生物学的試薬用化合物
CL2007002994A1 (es) 2006-10-19 2008-02-08 Wyeth Corp Compuestos derivados heterociclicos que contienen sulfamoilo, inhibidores de hsp90; composicion farmaceutica; y uso para el tratamiento del cancer, tal como cancer de mama, de colon y prostata, entre otros.
TWI433674B (zh) 2006-12-28 2014-04-11 Infinity Discovery Inc 環杷明(cyclopamine)類似物類
AR070949A1 (es) * 2007-10-19 2010-05-19 Solvay Pharm Gmbh Compuestos derivados de sulfamato de uso medico, medicamentos y composiciones farmaceuticas que los comprenden, procedimientos para preparar estos compuestos y su uso
TW201012803A (en) * 2008-06-06 2010-04-01 Organon Nv Heterocyclic derivatives
WO2010115952A1 (en) * 2009-04-09 2010-10-14 N.V. Organon Indane derivatives
BR112012011427B8 (pt) * 2009-11-13 2021-05-25 Celgene Int Ii Sarl moduladores seletivos de receptor de esfingosina 1 fosfato, seu uso, e composição
CN102753022B (zh) * 2009-11-13 2016-04-20 瑞塞普托斯公司 选择性的杂环1-磷酸鞘氨醇受体调节剂
WO2011097337A1 (en) * 2010-02-04 2011-08-11 Advanced Neural Dynamics, Inc. Novel sulfamides exhibiting neuroprotective action and methods for use thereof
US20120077814A1 (en) * 2010-09-10 2012-03-29 Zhong Wang Sulfonamide, sulfamate, and sulfamothioate derivatives

Also Published As

Publication number Publication date
JP5883135B2 (ja) 2016-03-09
US9018260B2 (en) 2015-04-28
PE20150284A1 (es) 2015-02-21
ZA201409248B (en) 2015-12-23
NZ702974A (en) 2016-03-31
AU2013278450A1 (en) 2015-01-22
AU2013278450B2 (en) 2017-04-20
RS56073B1 (sr) 2017-10-31
PL2865663T3 (pl) 2017-09-29
ME02753B (me) 2018-01-20
KR20150032838A (ko) 2015-03-30
CN104395285A (zh) 2015-03-04
SG11201408359PA (en) 2015-01-29
CA2877097A1 (en) 2013-12-27
IL236295A0 (en) 2015-02-26
HRP20170863T1 (hr) 2017-09-08
HK1207363A1 (en) 2016-01-29
PH12014502805A1 (en) 2015-02-23
MX355261B (es) 2018-04-12
RU2619937C2 (ru) 2017-05-22
BR112014031565A8 (pt) 2021-06-08
TWI597263B (zh) 2017-09-01
IL236295A (en) 2016-09-29
HUE033583T2 (hu) 2017-12-28
MX2014015492A (es) 2015-05-08
DK2865663T3 (en) 2017-06-19
KR101951519B1 (ko) 2019-02-22
EP2865663A1 (en) 2015-04-29
CY1119171T1 (el) 2018-02-14
BR112014031565A2 (pt) 2017-06-27
RU2014151013A (ru) 2016-08-10
JO3263B1 (ar) 2018-09-16
LT2865663T (lt) 2017-07-10
TW201402530A (zh) 2014-01-16
BR112014031565B1 (pt) 2022-04-12
CN104395285B (zh) 2016-04-13
EP2865663B1 (en) 2017-04-05
PT2865663T (pt) 2017-06-02
PH12014502805B1 (en) 2015-02-23
AR091506A1 (es) 2015-02-11
ES2628374T3 (es) 2017-08-02
WO2013191144A1 (ja) 2013-12-27
CL2014003429A1 (es) 2015-03-27
CA2877097C (en) 2018-08-07
MY169073A (en) 2019-02-13
EP2865663A4 (en) 2016-02-17
US20140371319A1 (en) 2014-12-18
JPWO2013191144A1 (ja) 2016-05-26

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