SI2755970T1 - Substituirani 2-(kroman-6-iloksi)-tiazoli in njihova uporaba kot farmacevtiki - Google Patents
Substituirani 2-(kroman-6-iloksi)-tiazoli in njihova uporaba kot farmacevtikiInfo
- Publication number
- SI2755970T1 SI2755970T1 SI201230609A SI201230609A SI2755970T1 SI 2755970 T1 SI2755970 T1 SI 2755970T1 SI 201230609 A SI201230609 A SI 201230609A SI 201230609 A SI201230609 A SI 201230609A SI 2755970 T1 SI2755970 T1 SI 2755970T1
- Authority
- SI
- Slovenia
- Prior art keywords
- chroman
- thiazoles
- yloxy
- pharmaceuticals
- substituted
- Prior art date
Links
- XFZODDHRWKDGLV-UHFFFAOYSA-N 2-(3,4-dihydro-2h-chromen-6-yloxy)-1,3-thiazole Chemical class C1=C2CCCOC2=CC=C1OC1=NC=CS1 XFZODDHRWKDGLV-UHFFFAOYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
- C07F9/655345—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11306128.7A EP2567958B1 (en) | 2011-09-12 | 2011-09-12 | Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals |
EP12756214.8A EP2755970B1 (en) | 2011-09-12 | 2012-09-10 | Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals |
PCT/EP2012/067622 WO2013037724A1 (en) | 2011-09-12 | 2012-09-10 | Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals |
Publications (1)
Publication Number | Publication Date |
---|---|
SI2755970T1 true SI2755970T1 (sl) | 2016-07-29 |
Family
ID=46801528
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201130350T SI2567958T1 (sl) | 2011-09-12 | 2011-09-12 | Substituirani 2-(kroman-6-iloksi)-tiazoli in njihova uporaba kot farmacevtiki |
SI201230609A SI2755970T1 (sl) | 2011-09-12 | 2012-09-10 | Substituirani 2-(kroman-6-iloksi)-tiazoli in njihova uporaba kot farmacevtiki |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201130350T SI2567958T1 (sl) | 2011-09-12 | 2011-09-12 | Substituirani 2-(kroman-6-iloksi)-tiazoli in njihova uporaba kot farmacevtiki |
Country Status (28)
Country | Link |
---|---|
US (1) | US20140243292A1 (sl) |
EP (2) | EP2567958B1 (sl) |
JP (1) | JP5941986B2 (sl) |
AR (1) | AR087822A1 (sl) |
BR (1) | BR112014005518A2 (sl) |
CO (1) | CO6930365A2 (sl) |
CR (1) | CR20140130A (sl) |
CY (2) | CY1115953T1 (sl) |
DK (2) | DK2567958T3 (sl) |
EA (1) | EA027998B1 (sl) |
EC (1) | ECSP14013309A (sl) |
ES (2) | ES2528143T3 (sl) |
GT (1) | GT201400044A (sl) |
HK (1) | HK1182107A1 (sl) |
HR (2) | HRP20150025T1 (sl) |
HU (1) | HUE029233T2 (sl) |
MX (1) | MX343176B (sl) |
NI (1) | NI201400017A (sl) |
PE (1) | PE20141121A1 (sl) |
PL (2) | PL2567958T3 (sl) |
PT (2) | PT2567958E (sl) |
RS (2) | RS53748B1 (sl) |
SI (2) | SI2567958T1 (sl) |
TN (1) | TN2014000106A1 (sl) |
TW (1) | TWI549952B (sl) |
UA (1) | UA114407C2 (sl) |
UY (1) | UY34320A (sl) |
WO (1) | WO2013037724A1 (sl) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5941637B2 (ja) * | 2011-09-12 | 2016-06-29 | サノフイ | 置換2−(クロマン−6−イルオキシ)−チアゾール及び医薬としてのその使用 |
TWI633095B (zh) * | 2013-03-08 | 2018-08-21 | 賽諾菲公司 | 經取代-6-基氧基-環烷類及其作為醫藥品之用途 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4168380A (en) | 1978-04-21 | 1979-09-18 | Hoffmann-La Roche Inc. | 7-Methoxy-5-oxo-5H-thiazolo[2,3-b]quinazoline-2-carboxylic acid |
JPH0967336A (ja) | 1995-09-04 | 1997-03-11 | Kanebo Ltd | 新規なイソチオウレア誘導体 |
AU726239B2 (en) | 1997-03-27 | 2000-11-02 | Taisho Pharmaceutical Co., Ltd. | 2-phenoxyaniline derivatives |
BR0013899A (pt) | 1999-09-10 | 2003-07-08 | Merck & Co Inc | Composto, composição farmacêutica, processos de tratamento ou prevenção de câncer, de uma doença em que a angiogênese esteja implicada, da vascularização retinal, da retinopatia diabética, da degeneração macular relacionada a idade, de doenças inflamatórias, de uma doença ou condições dependentes da tirosina quinase, de patologias associadas com ossos, e, processos para produzir uma composição farmacêutica, e de reduzir ou prevenir dano tecidual em seguida a um evento isquêmico cerebral |
WO2002032883A1 (fr) | 2000-10-18 | 2002-04-25 | Senju Pharmaceutical Co., Ltd. | Nouveau derive de 4-benzyloxyphenyle et utilisation de ce derive |
FI20011507A0 (fi) | 2001-07-10 | 2001-07-10 | Orion Corp | Uusia yhdisteitä |
AU2003244181A1 (en) | 2002-06-25 | 2004-01-06 | Yamanouchi Pharmaceutical Co., Ltd. | Phenoxypyridine derivative or salt thereof |
EP1570134B1 (de) * | 2002-12-13 | 2011-05-18 | Hansgrohe AG | Brausehalter |
FI20030030A0 (fi) | 2003-01-09 | 2003-01-09 | Orion Corp | Uusia yhdisteitä |
JP2006199941A (ja) * | 2004-12-20 | 2006-08-03 | Chisso Corp | クロマン環を有する化合物を含有する液晶組成物 |
CA2634147A1 (en) * | 2005-12-22 | 2007-06-28 | Icagen, Inc. | Calcium channel antagonists |
JP5092111B2 (ja) | 2007-02-05 | 2012-12-05 | トーアエイヨー株式会社 | ブトキシアニリン誘導体 |
EP2103939A1 (en) | 2008-03-20 | 2009-09-23 | sanofi-aventis | Fluorescence based assay to detect sodium/calcium exchanger (NCX) "reverse mode" modulating compounds |
US8354454B2 (en) | 2008-10-01 | 2013-01-15 | Merck Sharp & Dohme Corp. | Prodrugs of oxazolidinone CETP inhibitors |
JP5941637B2 (ja) * | 2011-09-12 | 2016-06-29 | サノフイ | 置換2−(クロマン−6−イルオキシ)−チアゾール及び医薬としてのその使用 |
US8912224B2 (en) * | 2011-09-12 | 2014-12-16 | Sanofi | Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals |
-
2011
- 2011-09-12 EP EP11306128.7A patent/EP2567958B1/en active Active
- 2011-09-12 RS RS20150022A patent/RS53748B1/en unknown
- 2011-09-12 DK DK11306128.7T patent/DK2567958T3/en active
- 2011-09-12 PL PL11306128T patent/PL2567958T3/pl unknown
- 2011-09-12 PT PT113061287T patent/PT2567958E/pt unknown
- 2011-09-12 SI SI201130350T patent/SI2567958T1/sl unknown
- 2011-09-12 ES ES11306128.7T patent/ES2528143T3/es active Active
-
2012
- 2012-09-10 SI SI201230609A patent/SI2755970T1/sl unknown
- 2012-09-10 MX MX2014002673A patent/MX343176B/es active IP Right Grant
- 2012-09-10 EA EA201490618A patent/EA027998B1/ru not_active IP Right Cessation
- 2012-09-10 PL PL12756214.8T patent/PL2755970T3/pl unknown
- 2012-09-10 ES ES12756214.8T patent/ES2578184T3/es active Active
- 2012-09-10 PE PE2014000332A patent/PE20141121A1/es active IP Right Grant
- 2012-09-10 PT PT127562148T patent/PT2755970T/pt unknown
- 2012-09-10 RS RS20160442A patent/RS54851B1/sr unknown
- 2012-09-10 DK DK12756214.8T patent/DK2755970T3/en active
- 2012-09-10 HU HUE12756214A patent/HUE029233T2/en unknown
- 2012-09-10 WO PCT/EP2012/067622 patent/WO2013037724A1/en active Application Filing
- 2012-09-10 EP EP12756214.8A patent/EP2755970B1/en active Active
- 2012-09-10 JP JP2014529013A patent/JP5941986B2/ja active Active
- 2012-09-10 AR ARP120103328A patent/AR087822A1/es unknown
- 2012-09-10 BR BR112014005518A patent/BR112014005518A2/pt not_active Application Discontinuation
- 2012-09-10 UA UAA201403780A patent/UA114407C2/uk unknown
- 2012-09-11 TW TW101133072A patent/TWI549952B/zh not_active IP Right Cessation
- 2012-09-12 UY UY0001034320A patent/UY34320A/es not_active Application Discontinuation
-
2013
- 2013-08-13 HK HK13109436.8A patent/HK1182107A1/xx not_active IP Right Cessation
-
2014
- 2014-03-03 NI NI201400017A patent/NI201400017A/es unknown
- 2014-03-07 GT GT201400044A patent/GT201400044A/es unknown
- 2014-03-11 TN TNP2014000106A patent/TN2014000106A1/en unknown
- 2014-03-11 US US14/204,220 patent/US20140243292A1/en not_active Abandoned
- 2014-03-18 CR CR20140130A patent/CR20140130A/es unknown
- 2014-04-08 CO CO14075065A patent/CO6930365A2/es unknown
- 2014-04-11 EC ECSP14013309 patent/ECSP14013309A/es unknown
-
2015
- 2015-01-09 HR HRP20150025AT patent/HRP20150025T1/hr unknown
- 2015-01-23 CY CY20151100076T patent/CY1115953T1/el unknown
-
2016
- 2016-06-16 HR HRP20160687TT patent/HRP20160687T1/hr unknown
- 2016-06-28 CY CY20161100582T patent/CY1118141T1/el unknown
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