SI2424495T1 - Treatment of leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones - Google Patents

Treatment of leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones Download PDF

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Publication number
SI2424495T1
SI2424495T1 SI201031630T SI201031630T SI2424495T1 SI 2424495 T1 SI2424495 T1 SI 2424495T1 SI 201031630 T SI201031630 T SI 201031630T SI 201031630 T SI201031630 T SI 201031630T SI 2424495 T1 SI2424495 T1 SI 2424495T1
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Slovenia
Prior art keywords
composition
tocotrienol
alpha
optical
atrophy
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SI201031630T
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English (en)
Slovenian (sl)
Inventor
Guy M. Miller
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Bioelectron Technology Corporation
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Publication of SI2424495T1 publication Critical patent/SI2424495T1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI201031630T 2009-04-28 2010-04-27 Treatment of leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones SI2424495T1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US21479509P 2009-04-28 2009-04-28
US31873310P 2010-03-29 2010-03-29
PCT/US2010/032624 WO2010126911A1 (en) 2009-04-28 2010-04-27 Treatment of leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones
EP10715650.7A EP2424495B1 (en) 2009-04-28 2010-04-27 Treatment of leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones

Publications (1)

Publication Number Publication Date
SI2424495T1 true SI2424495T1 (en) 2018-04-30

Family

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SI201031630T SI2424495T1 (en) 2009-04-28 2010-04-27 Treatment of leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones

Country Status (15)

Country Link
US (3) US20100273894A1 (https=)
EP (2) EP3332766A1 (https=)
JP (3) JP2012525399A (https=)
BR (1) BRPI1013376A8 (https=)
CA (1) CA2777479C (https=)
DK (1) DK2424495T3 (https=)
EA (1) EA031126B1 (https=)
ES (1) ES2662051T3 (https=)
HU (1) HUE037574T2 (https=)
MX (1) MX336800B (https=)
NO (1) NO2424495T3 (https=)
PL (1) PL2424495T3 (https=)
PT (1) PT2424495T (https=)
SI (1) SI2424495T1 (https=)
WO (1) WO2010126911A1 (https=)

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