SI2415484T1 - Pripravek, ki vsebuje lokalni anestetik SAIB, s podaljšanim sproščanjem - Google Patents
Pripravek, ki vsebuje lokalni anestetik SAIB, s podaljšanim sproščanjemInfo
- Publication number
- SI2415484T1 SI2415484T1 SI200531885T SI200531885T SI2415484T1 SI 2415484 T1 SI2415484 T1 SI 2415484T1 SI 200531885 T SI200531885 T SI 200531885T SI 200531885 T SI200531885 T SI 200531885T SI 2415484 T1 SI2415484 T1 SI 2415484T1
- Authority
- SI
- Slovenia
- Prior art keywords
- composition containing
- local anesthetic
- sustained local
- anesthetic composition
- containing saib
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 230000002459 sustained effect Effects 0.000 title abstract 2
- 239000003589 local anesthetic agent Substances 0.000 title 1
- UVGUPMLLGBCFEJ-SWTLDUCYSA-N sucrose acetate isobutyrate Chemical compound CC(C)C(=O)O[C@H]1[C@H](OC(=O)C(C)C)[C@@H](COC(=O)C(C)C)O[C@@]1(COC(C)=O)O[C@@H]1[C@H](OC(=O)C(C)C)[C@@H](OC(=O)C(C)C)[C@H](OC(=O)C(C)C)[C@@H](COC(C)=O)O1 UVGUPMLLGBCFEJ-SWTLDUCYSA-N 0.000 title 1
- 235000010983 sucrose acetate isobutyrate Nutrition 0.000 title 1
- 206010002091 Anaesthesia Diseases 0.000 abstract 1
- 230000037005 anaesthesia Effects 0.000 abstract 1
- 238000001949 anaesthesia Methods 0.000 abstract 1
- 230000003444 anaesthetic effect Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Dispersion Chemistry (AREA)
- Anesthesiology (AREA)
- Surgery (AREA)
- Neurology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Detergent Compositions (AREA)
- Selective Calling Equipment (AREA)
- Optical Communication System (AREA)
- Amplifiers (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61079704P | 2004-09-17 | 2004-09-17 | |
| US69139505P | 2005-06-17 | 2005-06-17 | |
| EP20110187311 EP2415484B1 (en) | 2004-09-17 | 2005-09-15 | Sustained local anesthetic composition containing SAIB |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2415484T1 true SI2415484T1 (sl) | 2014-10-30 |
Family
ID=35949130
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200532112A SI2767292T1 (sl) | 2004-09-17 | 2005-09-15 | Pripravek, ki vsebuje lokalni anestetik SAIB, s podaljšanim sproščanjem |
| SI200531885T SI2415484T1 (sl) | 2004-09-17 | 2005-09-15 | Pripravek, ki vsebuje lokalni anestetik SAIB, s podaljšanim sproščanjem |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200532112A SI2767292T1 (sl) | 2004-09-17 | 2005-09-15 | Pripravek, ki vsebuje lokalni anestetik SAIB, s podaljšanim sproščanjem |
Country Status (25)
| Country | Link |
|---|---|
| US (9) | US8753665B2 (enExample) |
| EP (4) | EP1809329B1 (enExample) |
| JP (2) | JP5285275B2 (enExample) |
| KR (2) | KR101492361B1 (enExample) |
| AT (1) | ATE537844T1 (enExample) |
| AU (1) | AU2005287175B2 (enExample) |
| BR (1) | BRPI0515372B8 (enExample) |
| CA (1) | CA2581287C (enExample) |
| CY (2) | CY1112625T1 (enExample) |
| DK (3) | DK2415484T3 (enExample) |
| EA (2) | EA201001885A1 (enExample) |
| ES (3) | ES2496765T3 (enExample) |
| GE (1) | GEP20094831B (enExample) |
| HR (1) | HRP20120254T1 (enExample) |
| HU (1) | HUE032040T2 (enExample) |
| IL (1) | IL181474A (enExample) |
| LT (1) | LT2767292T (enExample) |
| MX (1) | MX2007002962A (enExample) |
| NO (1) | NO342596B1 (enExample) |
| NZ (1) | NZ553369A (enExample) |
| PL (2) | PL2415484T3 (enExample) |
| PT (3) | PT2767292T (enExample) |
| RS (1) | RS52198B (enExample) |
| SI (2) | SI2767292T1 (enExample) |
| WO (1) | WO2006033948A2 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7833543B2 (en) * | 1995-06-07 | 2010-11-16 | Durect Corporation | High viscosity liquid controlled delivery system and medical or surgical device |
| US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| US20120225033A1 (en) * | 2010-11-24 | 2012-09-06 | Durect Corporation | Biodegradable Drug Delivery Composition |
| LT2767292T (lt) * | 2004-09-17 | 2016-12-12 | Durect Corporation | Palaikomosios vietinės anestezijos mišinys su saib |
| EP1793803B1 (en) * | 2004-10-01 | 2012-11-07 | Ramscor, Inc. | Conveniently implantable sustained release drug compositions |
| US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
| EP2117521B1 (en) * | 2006-11-03 | 2012-06-27 | Durect Corporation | Transdermal delivery systems comprising bupivacaine |
| TR201905174T4 (tr) * | 2007-03-28 | 2019-05-21 | Innocoll Pharm Ltd | Lokal analjezi, lokal anestezi veya sinir blokajı sağlamak için bir ilaç iletim cihazı. |
| EP2244679A4 (en) * | 2008-02-08 | 2013-10-09 | Qps Llc | NON-POLYMERIC COMPOSITIONS FOR CONTROLLED MEDICINAL PRODUCTION |
| WO2010077732A2 (en) * | 2008-12-09 | 2010-07-08 | Aether Medical Llc | Implantable analgesic |
| JP2012526845A (ja) | 2009-05-13 | 2012-11-01 | ケラプラスト テクノロジーズ, リミテッド | バイオポリマー材料 |
| PL3409271T3 (pl) * | 2012-05-16 | 2024-11-18 | Orexa B.V. | Środki znieczulające miejscowo dla ułatwienia przyjmowania i retencji pokarmu |
| WO2014143635A1 (en) * | 2013-03-15 | 2014-09-18 | Heron Therapeutics, Inc. | Compositions of a polyorthoester and an aprotic solvent |
| US10561746B2 (en) * | 2013-05-24 | 2020-02-18 | Danmarks Tekniske Universitet | Gel formulations for guiding radiotherapy |
| US20160303242A1 (en) | 2013-12-09 | 2016-10-20 | Durect Corporation | Pharmaceutically Active Agent Complexes, Polymer Complexes, and Compositions and Methods Involving the Same |
| WO2015123734A1 (en) * | 2014-02-21 | 2015-08-27 | The University Of Sydney | Liquid carrier materials |
| CA2946281C (en) | 2014-04-21 | 2022-12-13 | Heron Therapeutics, Inc. | Long-acting polymeric delivery systems |
| EP3509601A1 (en) | 2014-04-21 | 2019-07-17 | Heron Therapeutics, Inc. | A pharmaceutical composition comprising a delivery system, an amide-type local anesthetic, and meloxicam |
| GB201505527D0 (en) | 2015-03-31 | 2015-05-13 | Jmedtech Pte Ltd | Composition |
| KR20170025011A (ko) | 2015-08-27 | 2017-03-08 | 고려대학교 산학협력단 | 통증완화약물의 지속성 방출을 위한 약학적 조성물 및 그 투여를 위한 투여 장치 |
| US20190209538A1 (en) * | 2016-05-05 | 2019-07-11 | Liquidia Technologies, Inc. | Precision Controlled Load and Release Particles for Post-Operative Pain |
| AU2017290143A1 (en) * | 2016-06-30 | 2019-02-21 | Durect Corporation | Depot formulations |
| US10682340B2 (en) | 2016-06-30 | 2020-06-16 | Durect Corporation | Depot formulations |
| CN110325179A (zh) * | 2016-12-26 | 2019-10-11 | 塞尔利克斯生物私人有限公司 | 用于治疗慢性疼痛的组合物和方法 |
| JP6923122B2 (ja) * | 2017-03-27 | 2021-08-18 | フルーティー ホールディングス リミテッドFruithy Holdings Limited | 難溶性複合物又はその溶媒和物、薬物組成物及びその応用 |
| WO2019071246A2 (en) | 2017-10-06 | 2019-04-11 | Foundry Therapeutics, Inc. | IMPLANTABLE DEPOSITS FOR CONTROLLED RELEASE OF ANALGESICS TO TREAT POSTOPERATIVE PAIN, AND DEVICES, SYSTEMS, AND RELATED METHODS |
| RU2674025C1 (ru) * | 2017-10-25 | 2018-12-04 | Общество с ограниченной ответственностью "Научно-производственная фирма "ЭЛЕСТ" (ООО "НПФ "ЭЛЕСТ") | Лекарственное средство на основе порфиринового фотосенсибилизатора копропорфирина для лечения рака кожи методом фотодинамической терапии |
| US12364792B2 (en) | 2018-01-08 | 2025-07-22 | Foundry Therapeutics, Inc. | Devices, systems, and methods for treating intraluminal cancer via controlled delivery of therapeutic agents |
| WO2019221853A1 (en) | 2018-05-12 | 2019-11-21 | Foundry Therapeutics, Inc. | Implantable depots for the controlled release of therapeutic agents |
| WO2020047013A1 (en) | 2018-08-28 | 2020-03-05 | Foundry Therapeutics, Inc. | Polymer implants |
| EP4087540A4 (en) * | 2020-01-06 | 2024-01-10 | Pacira Pharmaceuticals, Inc. | TREATMENT OF PAIN ASSOCIATED WITH CAESAREAN SECTION SURGERY WITH SUSTAINED-RELEASE LIPOSOMAL ANESTHESIC COMPOSITIONS |
| WO2021141963A1 (en) | 2020-01-10 | 2021-07-15 | Pacira Pharmaceuticals, Inc. | Treatment of pain by subarachnoid administration of sustained-release liposomal anesthetic compositions |
| WO2021141959A1 (en) | 2020-01-10 | 2021-07-15 | Pacira Pharmaceuticals, Inc. | Treatment of pain by administration of sustained-release liposomal anesthetic compositions |
| CA3167217A1 (en) | 2020-01-13 | 2021-07-22 | Durect Corporation | Sustained release drug delivery systems with reduced impurities and related methods |
| US20230190650A1 (en) * | 2020-02-25 | 2023-06-22 | The University Of North Carolina At Chapel Hill | Eutectic based anesthetic compositions and applications thereof |
| BR112023013685A2 (pt) | 2021-01-11 | 2023-11-14 | Pacira Pharmaceuticals Inc | Tratamento da dor no quadril com composições anestésicas lipossômicas de liberação sustentada |
| EP4277702A1 (en) | 2021-01-12 | 2023-11-22 | Durect Corporation | Sustained release drug delivery systems and related methods |
| CN115068414B (zh) * | 2021-03-16 | 2023-07-21 | 湖南慧泽生物医药科技有限公司 | 供注射用罗哌卡因长效溶液制剂及其制备方法 |
| BR112023018896A2 (pt) | 2021-03-19 | 2023-10-10 | Pacira Pharmaceuticals Inc | Tratamento da dor em pacientes pediátricos por administração de composições anestésicas lipossômicas de liberação prolongada |
| CN115414324A (zh) * | 2021-05-31 | 2022-12-02 | 中国科学院过程工程研究所 | 一种载局部麻醉药的乳剂及其制备方法 |
| US11918572B2 (en) | 2022-01-28 | 2024-03-05 | Rebel Medicine Inc | Pharmaceutical compositions for treating pain |
| US11918565B1 (en) | 2022-11-03 | 2024-03-05 | Pacira Pharmaceuticals, Inc. | Treatment of post-operative pain via sciatic nerve block with sustained-release liposomal anesthetic compositions |
| US12226610B2 (en) | 2022-11-03 | 2025-02-18 | Pacira Pharmaceuticals, Inc. | Treatment of pain associated with total knee arthroplasty with sustained-release liposomal anesthetic compositions |
Family Cites Families (147)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US556450A (en) * | 1896-03-17 | Antifriction-bearing | ||
| US2931802A (en) | 1958-04-30 | 1960-04-05 | Eastman Kodak Co | Mixed esters of glucose and sucrose |
| GB1088992A (en) | 1963-09-19 | 1967-10-25 | Squibb & Sons Inc | Protective dressings |
| US4411890A (en) | 1981-04-14 | 1983-10-25 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
| US3743398A (en) | 1971-03-22 | 1973-07-03 | Eastman Kodak Co | Motion picture projector |
| NO139560C (no) | 1972-04-29 | 1979-04-04 | Takeda Chemical Industries Ltd | Analogifremgangsmaate til fremstilling av terapeutisk virksomme nonapeptidamid-derivater |
| US3992365A (en) | 1973-11-01 | 1976-11-16 | Burroughs Wellcome Co. | Agonist analogues of luteinizing hormone releasing hormone |
| DE2438352A1 (de) | 1974-08-09 | 1976-02-26 | Hoechst Ag | Peptidcyclopropylamide mit lh-rh/fshrh-wirkung |
| DE2438350C3 (de) | 1974-08-09 | 1979-06-13 | Hoechst Ag, 6000 Frankfurt | Peptide mit starker LH-RH/FSH-RH-Wirkung, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen |
| GB1524747A (en) | 1976-05-11 | 1978-09-13 | Ici Ltd | Polypeptide |
| US4360019A (en) | 1979-02-28 | 1982-11-23 | Andros Incorporated | Implantable infusion device |
| JPS55154991A (en) | 1979-05-23 | 1980-12-02 | Hisamitsu Pharmaceut Co Inc | Beta-d-fructopyranoside derivative |
| NZ194405A (en) | 1979-08-02 | 1982-05-25 | Dut Pty Ltd | Producing liquid hydrocarbon streams by hydrogenation of fossil-based feedstock |
| US4692147A (en) | 1980-04-02 | 1987-09-08 | Medtronic, Inc. | Drug administration device |
| IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| US4530840A (en) | 1982-07-29 | 1985-07-23 | The Stolle Research And Development Corporation | Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents |
| US4487603A (en) | 1982-11-26 | 1984-12-11 | Cordis Corporation | Implantable microinfusion pump system |
| DE3716302C2 (de) | 1987-05-15 | 1996-02-01 | Henkel Kgaa | Verbesserte resorbierbare Knochenwachse und ihre Verwendung |
| US4906474A (en) | 1983-03-22 | 1990-03-06 | Massachusetts Institute Of Technology | Bioerodible polyanhydrides for controlled drug delivery |
| JPS59210024A (ja) | 1983-05-13 | 1984-11-28 | Taiyo Kagaku Kk | トコフエロ−ル乳化物 |
| US4622219A (en) | 1983-06-17 | 1986-11-11 | Haynes Duncan H | Method of inducing local anesthesia using microdroplets of a general anesthetic |
| US4725442A (en) | 1983-06-17 | 1988-02-16 | Haynes Duncan H | Microdroplets of water-insoluble drugs and injectable formulations containing same |
| JPS607418U (ja) | 1983-06-28 | 1985-01-19 | 株式会社デンソー | 歯付スラストワツシヤをもつ軸受装置 |
| US4891225A (en) | 1984-05-21 | 1990-01-02 | Massachusetts Institute Of Technology | Bioerodible polyanhydrides for controlled drug delivery |
| US4630019A (en) | 1984-09-28 | 1986-12-16 | Westinghouse Electric Corp. | Molded case circuit breaker with calibration adjusting means for a bimetal |
| US4725852A (en) | 1985-05-09 | 1988-02-16 | Burlington Industries, Inc. | Random artificially perturbed liquid apparatus and method |
| US4780320A (en) | 1986-04-29 | 1988-10-25 | Pharmetrix Corp. | Controlled release drug delivery system for the periodontal pocket |
| EP0249347B1 (en) | 1986-06-10 | 1994-06-29 | Euroceltique S.A. | Controlled release dihydrocodeine composition |
| US4970075A (en) | 1986-07-18 | 1990-11-13 | Euroceltique, S.A. | Controlled release bases for pharmaceuticals |
| US4861598A (en) | 1986-07-18 | 1989-08-29 | Euroceltique, S.A. | Controlled release bases for pharmaceuticals |
| IT1198449B (it) | 1986-10-13 | 1988-12-21 | F I D I Farmaceutici Italiani | Esteri di alcoli polivalenti di acido ialuronico |
| GB8626098D0 (en) | 1986-10-31 | 1986-12-03 | Euro Celtique Sa | Controlled release hydromorphone composition |
| US5234520A (en) | 1987-03-20 | 1993-08-10 | Morgan Adhesives Co. | Method of making an adhesive construction |
| US5391381A (en) | 1987-06-25 | 1995-02-21 | Alza Corporation | Dispenser capable of delivering plurality of drug units |
| US4795641A (en) | 1987-08-20 | 1989-01-03 | Eastman Kodak Company | Polymer blends having reverse phase morphology for controlled delivery of bioactive agents |
| US5350741A (en) | 1988-07-30 | 1994-09-27 | Kanji Takada | Enteric formulations of physiologically active peptides and proteins |
| US5702716A (en) | 1988-10-03 | 1997-12-30 | Atrix Laboratories, Inc. | Polymeric compositions useful as controlled release implants |
| US4938763B1 (en) | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
| US4987893A (en) | 1988-10-12 | 1991-01-29 | Rochal Industries, Inc. | Conformable bandage and coating material |
| US5324520A (en) | 1988-12-19 | 1994-06-28 | Vipont Pharmaceutical, Inc. | Intragingival delivery systems for treatment of periodontal disease |
| US5324519A (en) | 1989-07-24 | 1994-06-28 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
| US5188837A (en) | 1989-11-13 | 1993-02-23 | Nova Pharmaceutical Corporation | Lipsopheres for controlled delivery of substances |
| GB8926612D0 (en) | 1989-11-24 | 1990-01-17 | Erba Farmitalia | Pharmaceutical compositions |
| IT1240643B (it) | 1990-05-11 | 1993-12-17 | Mediolanum Farmaceutici Spa | Peptidi biologicamente attivi contenenti in catena 2-alchiltriptofano |
| US5110685A (en) | 1990-05-18 | 1992-05-05 | Exxon Chemical Patents, Inc. | Low friction, abrasion resistant polymer coating |
| US5149543A (en) | 1990-10-05 | 1992-09-22 | Massachusetts Institute Of Technology | Ionically cross-linked polymeric microcapsules |
| US5399363A (en) | 1991-01-25 | 1995-03-21 | Eastman Kodak Company | Surface modified anticancer nanoparticles |
| EP0539559A1 (en) | 1991-04-03 | 1993-05-05 | Eastman Kodak Company | HIGH DURABILITY MASK FOR DRY ETCHING OF GaAs |
| JP3313124B2 (ja) | 1991-07-31 | 2002-08-12 | 森下仁丹株式会社 | 親水性物質を内容物とするシームレスカプセルおよびその製法 |
| DE69231536T2 (de) | 1991-08-26 | 2001-06-13 | Abbott Laboratories, Abbott Park | Verbindungen und methoden zur sublingualen oder buccalen verabreichung von therapeutischen agentien |
| US5487898A (en) | 1991-08-26 | 1996-01-30 | Abbott Laboratories | Compositions and method for the sublingual or buccal administration therapeutic agents |
| IL103275A0 (en) | 1991-10-01 | 1993-02-21 | Lilly Co Eli | Injectable extended release formulations and methods |
| YU87892A (sh) | 1991-10-01 | 1995-12-04 | Eli Lilly And Company Lilly Corporate Center | Injektibilne formulacije produženog otpuštanja i postupci za njihovo dobijanje i primenu |
| AU2605592A (en) | 1991-10-15 | 1993-04-22 | Atrix Laboratories, Inc. | Polymeric compositions useful as controlled release implants |
| EP0609345B1 (en) | 1991-10-21 | 1999-09-22 | Peptech Limited | Biocompatible implant for the timing of ovulation in mares |
| US5656295A (en) | 1991-11-27 | 1997-08-12 | Euro-Celtique, S.A. | Controlled release oxycodone compositions |
| US5266331A (en) | 1991-11-27 | 1993-11-30 | Euroceltique, S.A. | Controlled release oxycodone compositions |
| CA2125148C (en) | 1991-12-05 | 1999-05-11 | Siva N. Raman | A carbohydrate glass matrix for the sustained release of a therapeutic agent |
| EP0616526A1 (en) | 1991-12-11 | 1994-09-28 | The Procter & Gamble Company | Cetylpyridinium chloride and domiphen bromide in organic solvent |
| US5478577A (en) | 1993-11-23 | 1995-12-26 | Euroceltique, S.A. | Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level |
| MX9301823A (es) | 1992-03-30 | 1994-01-31 | Alza Corp | Composicion para el suministro de liberacion controlado de un agente biologicamente activo. |
| US5618563A (en) | 1992-09-10 | 1997-04-08 | Children's Medical Center Corporation | Biodegradable polymer matrices for sustained delivery of local anesthetic agents |
| US5922340A (en) * | 1992-09-10 | 1999-07-13 | Children's Medical Center Corporation | High load formulations and methods for providing prolonged local anesthesia |
| NZ261250A (en) | 1993-01-06 | 1997-08-22 | Kinerton Ltd | Ionic conjugates of polypeptides |
| US5340572A (en) | 1993-02-08 | 1994-08-23 | Insite Vision Incorporated | Alkaline ophthalmic suspensions |
| NZ263410A (en) | 1993-03-17 | 1997-05-26 | Minnesota Mining & Mfg | Pharmaceutical aerosol containing diol-diacid derived dispersing aid |
| WO1994021229A1 (en) | 1993-03-17 | 1994-09-29 | Minnesota Mining And Manufacturing Company | Aerosol formulation containing an ester-, amide-, or mercaptoester-derived dispersing aid |
| DK44193D0 (da) | 1993-04-20 | 1993-04-20 | Euromed I S | Saarforbinding og klaebemiddel til en saarforbinding eller lignende |
| IL110014A (en) | 1993-07-01 | 1999-11-30 | Euro Celtique Sa | Solid controlled-release oral dosage forms of opioid analgesics |
| JP3257750B2 (ja) | 1993-07-20 | 2002-02-18 | エチコン・インコーポレーテツド | ε−カプロラクトンおよびラクチドの液状コポリマー |
| US5879705A (en) | 1993-07-27 | 1999-03-09 | Euro-Celtique S.A. | Sustained release compositions of morphine and a method of preparing pharmaceutical compositions |
| JPH07112940A (ja) | 1993-08-26 | 1995-05-02 | Takeda Chem Ind Ltd | 徐放性非経口投与製剤およびその製造方法 |
| WO1995009613A1 (en) | 1993-10-04 | 1995-04-13 | Mark Chasin | Controlled release microspheres |
| ATE220894T1 (de) | 1993-12-29 | 2002-08-15 | Matrix Pharma | Zusammensetzung für lokale freigabe von zytostatika |
| DE69534780T2 (de) | 1994-04-08 | 2006-10-05 | Qlt Usa Inc., Fort Collins | Flüssige Zusammensetzungen zur Arzneistoffabgabe |
| US5633000A (en) | 1994-06-23 | 1997-05-27 | Axxia Technologies | Subcutaneous implant |
| EP0782569B1 (en) | 1994-09-23 | 2002-03-20 | Darwin Discovery Limited | Racemisation process used in the manufacture of levobupivacaine and analogues thereof |
| US5599852A (en) | 1994-10-18 | 1997-02-04 | Ethicon, Inc. | Injectable microdispersions for soft tissue repair and augmentation |
| US5994548A (en) | 1994-10-25 | 1999-11-30 | Darwin Discovery Ltd. | Crystallisation of levibupivacaine and analogues thereof |
| PT788481E (pt) | 1994-10-25 | 2004-01-30 | Darwin Discovery Ltd | Processo para preparacao de levobupivacaina e seus analogos |
| GB9501071D0 (en) | 1995-01-18 | 1995-03-08 | Chiroscience Ltd | Racemisation |
| US6384227B2 (en) | 1995-01-18 | 2002-05-07 | Darwin Discovery Ltd. | Racemisation process for use in the manufacture of levobupivacaine and related piperidinecarboxanilide anaesthetic agents |
| US5968542A (en) | 1995-06-07 | 1999-10-19 | Southern Biosystems, Inc. | High viscosity liquid controlled delivery system as a device |
| US7833543B2 (en) | 1995-06-07 | 2010-11-16 | Durect Corporation | High viscosity liquid controlled delivery system and medical or surgical device |
| DK1006935T3 (da) | 1995-06-07 | 2005-06-06 | Durect Corp | Styret afgivelsessystem med en væske med höj viskositet |
| US6413536B1 (en) | 1995-06-07 | 2002-07-02 | Southern Biosystems, Inc. | High viscosity liquid controlled delivery system and medical or surgical device |
| US5747058A (en) * | 1995-06-07 | 1998-05-05 | Southern Biosystems, Inc. | High viscosity liquid controlled delivery system |
| CN1156961A (zh) | 1995-06-09 | 1997-08-13 | 欧罗赛铁克股份有限公司 | 产生长效局部麻醉的制剂和方法 |
| US5736152A (en) | 1995-10-27 | 1998-04-07 | Atrix Laboratories, Inc. | Non-polymeric sustained release delivery system |
| ES2246004T3 (es) | 1996-02-02 | 2006-02-01 | Alza Corporation | Liberacion prolongada de un agente activo usando un sistema implantable. |
| US6245351B1 (en) | 1996-03-07 | 2001-06-12 | Takeda Chemical Industries, Ltd. | Controlled-release composition |
| AU733867B2 (en) | 1996-06-24 | 2001-05-31 | Euro-Celtique S.A. | Methods for providing safe local anesthesia |
| US5869669A (en) | 1996-07-26 | 1999-02-09 | Penick Corporation | Preparation of 14-hydroxynormorphinones from normorphinone dienol acylates |
| US6046187A (en) * | 1996-09-16 | 2000-04-04 | Children's Medical Center Corporation | Formulations and methods for providing prolonged local anesthesia |
| US5747051A (en) | 1996-09-27 | 1998-05-05 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing an amide of a hydroxy fatty acid and a retinoid |
| US6479074B2 (en) | 1996-10-24 | 2002-11-12 | Pharmaceutical Applications Associates Llc | Methods and transdermal compositions for pain relief |
| US6572880B2 (en) | 1996-10-24 | 2003-06-03 | Pharmaceutical Applications Associates Llc | Methods and transdermal compositions for pain relief |
| WO1998027963A2 (en) | 1996-12-20 | 1998-07-02 | Alza Corporation | Gel composition and methods |
| US6203813B1 (en) | 1997-01-13 | 2001-03-20 | Lance L. Gooberman | Pharmaceutical delivery device and method of preparation therefor |
| US6126919A (en) | 1997-02-07 | 2000-10-03 | 3M Innovative Properties Company | Biocompatible compounds for pharmaceutical drug delivery systems |
| DE19714765A1 (de) | 1997-04-10 | 1998-10-15 | Merck Patent Gmbh | Verwendung von niedermolekularen, oligomeren Estern von alpha-Hydroxysäuren und/oder aromatischen o-Hydroxysäuren in kosmetischen Formulierungen |
| US5919473A (en) | 1997-05-12 | 1999-07-06 | Elkhoury; George F. | Methods and devices for delivering opioid analgesics to wounds via a subdermal implant |
| US5840329A (en) | 1997-05-15 | 1998-11-24 | Bioadvances Llc | Pulsatile drug delivery system |
| US6051558A (en) | 1997-05-28 | 2000-04-18 | Southern Biosystems, Inc. | Compositions suitable for controlled release of the hormone GnRH and its analogs |
| US6403609B1 (en) | 1997-07-29 | 2002-06-11 | Alcon Manufacturing, Ltd. | Ophthalmic compositions containing galactomannan polymers and borate |
| ES2209217T3 (es) | 1997-11-19 | 2004-06-16 | Darwin Discovery Limited | Formulacion anestesica. |
| RU2180557C2 (ru) * | 1998-06-26 | 2002-03-20 | Казахский Государственный национальный университет им. Аль-Фараби | Анестезирующий состав пролонгированного действия |
| IL140420A0 (en) | 1998-06-29 | 2002-02-10 | Pharmaceuticals Applic Associa | Methods and transdermal compositions for pain relief |
| US6312717B1 (en) | 1998-07-07 | 2001-11-06 | Bristol-Myers Squibb Company | Method for treatment of anxiety and depression |
| DE19858891A1 (de) | 1998-12-19 | 2000-06-21 | Merck Patent Gmbh | Verbesserte Knochensiegel |
| US6498153B1 (en) | 1998-12-31 | 2002-12-24 | Akzo Nobel N.V. | Extended release growth promoting two component composition |
| US6291013B1 (en) | 1999-05-03 | 2001-09-18 | Southern Biosystems, Inc. | Emulsion-based processes for making microparticles |
| AU763945B2 (en) * | 1999-06-04 | 2003-08-07 | Skyepharma Inc. | Oil-core compositions for the sustained release of hydrophobic drugs |
| WO2000078335A1 (en) | 1999-06-18 | 2000-12-28 | Southern Biosystems, Inc. | COMPOSITIONS FOR CONTROLLED RELEASE OF THE HORMONE GnRH AND ITS ANALOGS |
| CZ20022047A3 (cs) * | 1999-12-23 | 2003-09-17 | Pfizer Products Inc. | Farmaceutické kompozice poskytující zvýšenou koncentraci léčiva |
| PT1248596E (pt) | 2000-01-11 | 2007-06-21 | Bertex Pharma Gmbh | Kit para implantações contendo uma fase de veículo e um solvente |
| BR0002246A (pt) | 2000-04-06 | 2003-04-15 | Cristalia Prod Quimicos Farm | Processo de obtenção dos enantiÈmeros da bupivacaìna racêmica, processo de obtenção de composições farmacêuticas a base de levobupivacaìna: composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis e utilização das composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis |
| ES2253375T3 (es) | 2000-04-19 | 2006-06-01 | Genentech, Inc. | Formulaciones de liberacion sostenida. |
| US20050042194A1 (en) | 2000-05-11 | 2005-02-24 | A.P. Pharma, Inc. | Semi-solid delivery vehicle and pharmaceutical compositions |
| WO2002010436A2 (en) | 2000-07-28 | 2002-02-07 | The Brigham And Women's Hospital, Inc. | Prognostic classification of breast cancer |
| FR2814308B1 (fr) | 2000-09-15 | 2003-03-14 | France Telecom | Procede de gestion de l'usage d'une ligne de telecommunication et systeme de mise en oeuvre |
| US6733783B2 (en) | 2000-10-30 | 2004-05-11 | Euro-Celtique S.A. | Controlled release hydrocodone formulations |
| EP1363602A4 (en) * | 2001-01-25 | 2006-01-11 | Euro Celtique Sa | LOCAL ANESTHESIA, AND METHOD OF USE |
| US7318931B2 (en) | 2001-06-21 | 2008-01-15 | Genentech, Inc. | Sustained release formulation |
| KR20040058100A (ko) * | 2001-11-14 | 2004-07-03 | 알자 코포레이션 | 주입가능한 데포 조성물 및 그의 용도 |
| FR2838349B1 (fr) | 2002-04-15 | 2004-06-25 | Laurence Paris | Compositions liquides pour capsules molle a liberation prolongee et leur procede de fabrication |
| SI2561860T1 (en) | 2002-05-31 | 2018-05-31 | Titan Pharmaceuticals, Inc. | An implantable polymeric device for prolonged release of buprenorphine |
| US20040109893A1 (en) | 2002-06-25 | 2004-06-10 | Guohua Chen | Sustained release dosage forms of anesthetics for pain management |
| US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| JP4417039B2 (ja) | 2002-06-28 | 2010-02-17 | 太陽化学株式会社 | 水中油滴型乳化組成物 |
| WO2004011032A1 (ja) | 2002-07-26 | 2004-02-05 | Mikasa Seiyaku Co., Ltd. | 外用剤 |
| PL375603A1 (en) | 2002-10-25 | 2005-12-12 | Pfizer Products Inc. | Depot formulations of arylheterocyclic active agents in the form of a suspension |
| MXPA05002561A (es) | 2002-10-25 | 2005-05-05 | Pfizer Prod Inc | Nuevas formulaciones de liberacion prolongada inyectables. |
| HUE026034T2 (en) | 2002-12-13 | 2016-05-30 | Durect Corp | Oral delivery system containing an oral high-viscosity carrier |
| KR20050088196A (ko) | 2002-12-19 | 2005-09-02 | 알자 코포레이션 | 안정한 비수성 단일 상 겔 및 이식가능한 장치로부터전달하기 위한 이의 제형 |
| DE10312346A1 (de) | 2003-03-20 | 2004-09-30 | Bayer Healthcare Ag | Kontrolliertes Freisetzungssystem |
| DE10322469A1 (de) | 2003-05-19 | 2004-12-16 | Bayer Healthcare Ag | Heterocyclische Verbindungen |
| US20050106304A1 (en) | 2003-11-14 | 2005-05-19 | Cook Phillip M. | Sucrose acetate isobutyrate formulation |
| US20050171052A1 (en) | 2003-11-14 | 2005-08-04 | Cook Phillip M. | Sucrose acetate isobutyrate formulation |
| US20050232876A1 (en) | 2004-04-19 | 2005-10-20 | Robin Lynn Minga | Skin care compositions |
| EP1758095A4 (en) | 2004-05-14 | 2008-10-01 | Yanmar Co Ltd | CABIN NOISE SUPPRESSION STRUCTURE |
| US20050266087A1 (en) | 2004-05-25 | 2005-12-01 | Gunjan Junnarkar | Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium |
| LT2767292T (lt) * | 2004-09-17 | 2016-12-12 | Durect Corporation | Palaikomosios vietinės anestezijos mišinys su saib |
| JP2008528698A (ja) | 2005-02-03 | 2008-07-31 | インターシア セラピューティクス,インコーポレイティド | 埋め込み可能なインターフェロン含有デバイス |
| SA07280459B1 (ar) | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
| JP5194273B2 (ja) | 2007-09-20 | 2013-05-08 | 三菱電機株式会社 | 半導体装置 |
| SE531980C2 (sv) | 2008-01-17 | 2009-09-22 | Avtech Sweden Ab | Flygstyrningsförfarande samt datorprogram och datorprogramprodukt för att genomföra förfarandet |
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