SI2176253T1 - Postopek priprave ali čiščenja olmesartan medoksomila ali hidrohalidne soli olmesartan medoksomila - Google Patents

Postopek priprave ali čiščenja olmesartan medoksomila ali hidrohalidne soli olmesartan medoksomila

Info

Publication number
SI2176253T1
SI2176253T1 SI200830507T SI200830507T SI2176253T1 SI 2176253 T1 SI2176253 T1 SI 2176253T1 SI 200830507 T SI200830507 T SI 200830507T SI 200830507 T SI200830507 T SI 200830507T SI 2176253 T1 SI2176253 T1 SI 2176253T1
Authority
SI
Slovenia
Prior art keywords
olmesartan medoxomil
purification
preparation
hydrohalide salt
olmesartan
Prior art date
Application number
SI200830507T
Other languages
English (en)
Slovenian (sl)
Inventor
Samo Pirc
Lovro Selic
Original Assignee
Lek Pharmaceuticals D.D.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP07114004A external-priority patent/EP2036904A1/en
Priority claimed from EP07114000A external-priority patent/EP2022790A1/en
Application filed by Lek Pharmaceuticals D.D. filed Critical Lek Pharmaceuticals D.D.
Publication of SI2176253T1 publication Critical patent/SI2176253T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SI200830507T 2007-08-08 2008-08-07 Postopek priprave ali čiščenja olmesartan medoksomila ali hidrohalidne soli olmesartan medoksomila SI2176253T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP07114004A EP2036904A1 (en) 2007-08-08 2007-08-08 A process for the preparation of olmesartan medoxomil
EP07114000A EP2022790A1 (en) 2007-08-08 2007-08-08 A process for the preparation or purification of olmesartan medoxomil
PCT/EP2008/060396 WO2009019303A2 (en) 2007-08-08 2008-08-07 A process for the preparation or purification of olmesartan medoxomil
EP08786993A EP2176253B1 (en) 2007-08-08 2008-08-07 A process for the preparation or purification of olmesartan medoxomil or olmesartan medoxomil hydrohalide salt

Publications (1)

Publication Number Publication Date
SI2176253T1 true SI2176253T1 (sl) 2012-02-29

Family

ID=39789494

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200830507T SI2176253T1 (sl) 2007-08-08 2008-08-07 Postopek priprave ali čiščenja olmesartan medoksomila ali hidrohalidne soli olmesartan medoksomila

Country Status (9)

Country Link
US (2) US20110224271A1 (enExample)
EP (2) EP2176253B1 (enExample)
JP (2) JP2010535743A (enExample)
CN (2) CN101778842B (enExample)
AT (1) ATE528305T1 (enExample)
BR (2) BRPI0815111A2 (enExample)
CA (2) CA2707365A1 (enExample)
SI (1) SI2176253T1 (enExample)
WO (2) WO2009019304A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2707365A1 (en) * 2007-08-08 2009-02-12 Lek Pharmaceuticals D.D. A process for the preparation of olmesartan medoxomil
KR101630885B1 (ko) 2008-06-09 2016-06-15 다이이찌 산쿄 가부시키가이샤 1-비페닐메틸이미다졸 화합물의 제조 방법
CA2760031C (en) * 2009-04-28 2015-03-10 Daiichi Sankyo Company, Limited Acetone solvate crystals of trityl olmesartan medoxomil
ES2527686T3 (es) 2009-04-28 2015-01-28 Daiichi Sankyo Company, Limited Procedimiento de producción de olmesartán medoxomil
WO2011007368A2 (en) * 2009-07-14 2011-01-20 Cadila Healthcare Limited An improved process for preparation of olmesartan
CA2769704A1 (en) * 2009-07-31 2011-02-03 Ranbaxy Laboratories Limited Polymorphic form of olmesartan medoxomil
WO2011021224A2 (en) * 2009-08-19 2011-02-24 Msn Laboratories Limited Process for (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl4-(1-hydroxy-1-methylethyl)-2-propyl-1-[4-[2-tetrazol-5-yl)phenyl]phenyl]methylimidazole-5-carboxylate
CZ2010785A3 (cs) * 2010-10-29 2012-05-16 Zentiva, K.S. Zpusob výroby olmesartanu medoxomilu
KR101275092B1 (ko) * 2011-05-19 2013-06-17 한미정밀화학주식회사 아질사르탄의 개선된 제조방법
CN102351849B (zh) * 2011-10-26 2013-10-02 齐鲁天和惠世制药有限公司 一种奥美沙坦酯的制备方法
CN103304550B (zh) * 2012-03-16 2016-01-27 湖南欧亚生物有限公司 一种奥美沙坦酯的制备方法
CN103319461A (zh) * 2013-07-02 2013-09-25 临海天宇药业有限公司 奥美沙坦酯中间体的制备方法以及奥美沙坦酯的合成方法
CN103435602A (zh) * 2013-07-31 2013-12-11 山东省医学科学院药物研究所 一种奥美沙坦酯的制备方法
CN104262332A (zh) * 2014-09-16 2015-01-07 上海信谊百路达药业有限公司 一种奥美沙坦酯的制备方法
CN104447715B (zh) * 2014-11-28 2017-06-20 山东新华制药股份有限公司 奥美沙坦酯的制备方法
CN104817546B (zh) * 2015-05-20 2020-02-07 浙江华海药业股份有限公司 一种奥美沙坦酯母液回收的方法
CN107311990B (zh) * 2017-07-25 2021-09-03 浙江华海致诚药业有限公司 一种奥美沙坦酯的制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5616599A (en) * 1991-02-21 1997-04-01 Sankyo Company, Limited Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use
ATE199548T1 (de) * 1992-06-02 2001-03-15 Sankyo Co 4-carboxyimidazolderivate als angiotensin-ii- antagonisten und ihre therapeutische verwendung
JP2001226372A (ja) * 1999-12-06 2001-08-21 Sumika Fine Chemicals Co Ltd ロサルタンの結晶性または結晶化された酸付加塩およびロサルタンの精製方法
ITMI20032338A1 (it) * 2003-11-28 2005-05-29 Dinamite Dipharma S P A In Forma A Bbreviata Diph Composti feniltetrazolici.
CN1993355A (zh) * 2004-09-02 2007-07-04 特瓦制药工业有限公司 奥美沙坦酯的纯化方法
JP4437141B2 (ja) * 2004-09-02 2010-03-24 テバ ファーマシューティカル インダストリーズ リミティド オルメサルタンメドキソミルの精製法
GB2419592A (en) * 2004-10-26 2006-05-03 Cipla Ltd Process for the preparation of irbesartan hydrochloride
US20060281800A1 (en) 2005-04-12 2006-12-14 Glenmark Pharmaceuticals Limited Polymorphic form of olmesartan and process for its preparation
EA014026B1 (ru) 2005-07-29 2010-08-30 Крка, Товарна Здравил, Д.Д., Ново Место Способ получения олмесартан медоксомила
EP1816131A1 (en) 2006-02-06 2007-08-08 KRKA, tovarna zdravil, d.d., Novo mesto Process for the preparation of olmesartan medoxomil
WO2007052301A2 (en) 2005-08-31 2007-05-10 Alembic Limited Process for the preparation of irbesartan
EP1801111B1 (en) * 2005-12-20 2014-07-16 LEK Pharmaceuticals d.d. Novel polymorph forms of olmesartan medoxomil
CA2654218C (en) * 2006-04-07 2014-07-22 Lek Pharmaceuticals D.D. Process for the preparation of pure irbesartan
US8048904B2 (en) 2006-06-19 2011-11-01 Matrix Laboratories Ltd. Process for the preparation of olmesartan medoxomil
US8076492B2 (en) * 2006-10-09 2011-12-13 Cipla Limited Process for preparing trityl olmesartan medoxomil and olmesartan medoxomil
CA2707365A1 (en) * 2007-08-08 2009-02-12 Lek Pharmaceuticals D.D. A process for the preparation of olmesartan medoxomil

Also Published As

Publication number Publication date
US20110224271A1 (en) 2011-09-15
WO2009019303A3 (en) 2009-04-02
WO2009019303A2 (en) 2009-02-12
EP2176253A2 (en) 2010-04-21
CA2707334A1 (en) 2009-02-12
US8592474B2 (en) 2013-11-26
JP5685082B2 (ja) 2015-03-18
JP2010535743A (ja) 2010-11-25
CA2707365A1 (en) 2009-02-12
JP2010535742A (ja) 2010-11-25
BRPI0815111A2 (pt) 2015-01-27
US20110263666A1 (en) 2011-10-27
CN101778842B (zh) 2014-10-29
CN101778843A (zh) 2010-07-14
CA2707334C (en) 2015-11-24
EP2173741A1 (en) 2010-04-14
EP2173741B1 (en) 2013-10-02
ATE528305T1 (de) 2011-10-15
CN101778842A (zh) 2010-07-14
EP2176253B1 (en) 2011-10-12
WO2009019304A1 (en) 2009-02-12
BRPI0815134A2 (pt) 2015-02-03

Similar Documents

Publication Publication Date Title
SI2176253T1 (sl) Postopek priprave ali čiščenja olmesartan medoksomila ali hidrohalidne soli olmesartan medoksomila
MY149731A (en) Compounds
IN2012DN02756A (enExample)
UY32062A (es) Inhibidores de beta-secretasa
MX344238B (es) Compuestos de tetrazol y métodos para preparar y usar los mismos.
TN2011000414A1 (en) Pharmaceutical composition comprising linagliptin and optionally a sglt2 inhibitors, and uses thereof
MX2011011661A (es) Compuestos 1-cianoetilheterociclilcarboxamida sustituidos 750.
EA201171151A1 (ru) Кристаллические трипептидные ингибиторы эпоксикетон-протеазы
UA105033C2 (uk) Фармацевтична композиція, що включає глюкопіранозилзаміщене похідне бензолу, фармацевтична дозована форма, що містить зазначене похідне, їх застосування для лікування метаболічного порушення
GT201200164A (es) "nuevos compuestos de espiropiperidina"
IN2012DN01292A (enExample)
WO2010049449A3 (en) Novel salts of sunitinib
BRPI0911678B8 (pt) maleato de orvepitant cristalino anidro, composição farmacêutica compreedendo o dito maleato e uso do mesmo para o tratamento ou profilaxia de doenças do sistema nervoso central
WO2010098583A2 (ko) 스타틴 화합물 또는 그 염의 신규 제조방법, 및 이에 사용되는 중간체 화합물
UA94624C2 (uk) Арипіпразолу геміфумарат і спосіб його одержання
TN2010000266A1 (en) Oxazolidinones for the treatment and/or prophylaxis of heart failure
TW200800993A (en) Organic compounds
MX349563B (es) Formulacion farmaceutica de fenofibrato nanonizado.
MX2011008857A (es) Derivados de oxiindol con actividad agonistica del receptor de motilina.
WO2010146595A3 (en) Novel polymorphs of flibanserin hydrochloride
MX2010003056A (es) Polimorfos de valomaciclovir.
UA105167C2 (uk) Кальцієва сіль периндоприлу або її сольват
MX2010006218A (es) Compuestos organicos.
MY152069A (en) Substituted 3-benzofuranyl-indol-2-one-3-acetamidopiperazine derivatives, preparation threof, and therepeutic use thereof
GB0615105D0 (en) Novel compounds