GT201200164A - "nuevos compuestos de espiropiperidina" - Google Patents

"nuevos compuestos de espiropiperidina"

Info

Publication number
GT201200164A
GT201200164A GT201200164A GT201200164A GT201200164A GT 201200164 A GT201200164 A GT 201200164A GT 201200164 A GT201200164 A GT 201200164A GT 201200164 A GT201200164 A GT 201200164A GT 201200164 A GT201200164 A GT 201200164A
Authority
GT
Guatemala
Prior art keywords
spyropiperidine
compounds
new
composite
salt
Prior art date
Application number
GT201200164A
Other languages
English (en)
Inventor
Chafiq Hamdouchi
Pranab Maiti
Jayana Pankaj Lineswala
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43384775&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GT201200164(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of GT201200164A publication Critical patent/GT201200164A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4747—Quinolines; Isoquinolines spiro-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

Abstract

UN COMPUESTO DE LA FÓRMULA I, O UNA SAL DEL MISMO FARMACÉUTICAMENTE ACEPTABLE ASÍ COMO TAMBIÉN UNA COMPOSICIÓN FARMACÉUTICA Y UN MÉTODO PARA TRATAR LA DIABETES.
GT201200164A 2009-11-30 2012-05-28 "nuevos compuestos de espiropiperidina" GT201200164A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US26518109P 2009-11-30 2009-11-30

Publications (1)

Publication Number Publication Date
GT201200164A true GT201200164A (es) 2014-02-27

Family

ID=43384775

Family Applications (1)

Application Number Title Priority Date Filing Date
GT201200164A GT201200164A (es) 2009-11-30 2012-05-28 "nuevos compuestos de espiropiperidina"

Country Status (25)

Country Link
US (1) US8822486B2 (es)
EP (1) EP2507228B1 (es)
JP (1) JP5709889B2 (es)
KR (1) KR101410103B1 (es)
CN (1) CN102648195B (es)
AR (1) AR078948A1 (es)
AU (1) AU2010324987B2 (es)
BR (1) BR112012012903A2 (es)
CA (1) CA2781292C (es)
CL (1) CL2012001321A1 (es)
CR (1) CR20120296A (es)
DO (1) DOP2012000139A (es)
EA (1) EA020507B1 (es)
EC (1) ECSP12011930A (es)
ES (1) ES2526568T3 (es)
GT (1) GT201200164A (es)
IL (1) IL219594A0 (es)
MA (1) MA33840B1 (es)
MX (1) MX2012006233A (es)
NZ (1) NZ600203A (es)
PE (1) PE20121474A1 (es)
TN (1) TN2012000248A1 (es)
TW (1) TW201141866A (es)
WO (1) WO2011066183A1 (es)
ZA (1) ZA201203055B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR078522A1 (es) 2009-10-15 2011-11-16 Lilly Co Eli Compuesto de espiropiperidina, composicion farmaceutica que lo comprende, su uso para preparar un medicamento util para tratar diabetes y compuesto intermediario para su sintesis
MX2012007474A (es) 2009-12-25 2012-08-01 Mochida Pharm Co Ltd Derivados de 3-hidroxi-5-arilisotiazol novedosos.
US9040525B2 (en) 2010-10-08 2015-05-26 Mochida Pharmaceutical Co., Ltd. Cyclic amide derivative
AU2012248629A1 (en) 2011-04-27 2013-11-28 Mochida Pharmaceutical Co., Ltd. Novel 3-hydroxyisothiazole 1-oxide derivative
WO2012147516A1 (ja) 2011-04-28 2012-11-01 持田製薬株式会社 環状アミド誘導体
TWI537262B (zh) 2011-08-17 2016-06-11 美國禮來大藥廠 供治療糖尿病使用之新穎１，２，３，４－四氫喹啉衍生物
CA2905726C (en) * 2013-03-14 2022-05-31 Janssen Pharmaceutica Nv Gpr120 agonists for the treatment of type ii diabetes
CA2928097A1 (en) 2013-11-14 2015-07-02 Cadila Healthcare Limited Novel heterocyclic compounds
WO2015084692A1 (en) 2013-12-04 2015-06-11 Merck Sharp & Dohme Corp. Antidiabetic bicyclic compounds
WO2015119899A1 (en) 2014-02-06 2015-08-13 Merck Sharp & Dohme Corp. Antidiabetic compounds
WO2018166855A1 (en) 2017-03-16 2018-09-20 Basf Se Heterobicyclic substituted dihydroisoxazoles
US10710986B2 (en) 2018-02-13 2020-07-14 Gilead Sciences, Inc. PD-1/PD-L1 inhibitors
JP7242702B2 (ja) 2018-04-19 2023-03-20 ギリアード サイエンシーズ， インコーポレイテッド Ｐｄ－１／ｐｄ－ｌ１阻害剤
UA126421C2 (uk) 2018-07-13 2022-09-28 Гіліад Сайєнсіз, Інк. Інгібітори pd-1/pd-l1
CN112955435A (zh) 2018-10-24 2021-06-11 吉利德科学公司 Pd-1/pd-l1抑制剂
CN110590767B (zh) * 2019-08-29 2021-10-08 南方科技大学 一种合成amg837的方法
BR112022006546A2 (pt) 2019-10-07 2022-08-30 Kallyope Inc Agonistas de gpr119
AU2021275038A1 (en) 2020-05-19 2022-12-22 Kallyope, Inc. AMPK activators
CN116390925A (zh) 2020-06-26 2023-07-04 卡尔优普公司 Ampk活化剂

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0202133D0 (sv) * 2002-07-08 2002-07-08 Astrazeneca Ab Novel compounds
EP1613601A4 (en) 2003-04-04 2007-05-02 Merck & Co Inc ACYLATED SPIROPIPERIDINE DERIVATIVES AS AGONISTS FOR MELANOCORTIN-4 RECEPTOR
JP2007510662A (ja) 2003-11-04 2007-04-26 エリクシアー ファーマシューティカルズ， インコーポレイテッド 治療化合物およびその使用
EA011010B1 (ru) 2004-02-27 2008-12-30 Эмджен, Инк. Соединения, модулирующие рецептор gpr40, фармацевтическая композиция, способ лечения заболеваний, чувствительных к модулированию рецептора gpr40 (варианты), способ модулирования функции gpr40 (варианты) и способ модулирования циркулирующей концентрации инсулина
EP2253315A1 (en) 2004-03-30 2010-11-24 Takeda Pharmaceutical Company Limited Alkoxyphenylpropanoic acid derivatives
ATE429426T1 (de) * 2004-09-07 2009-05-15 Banyu Pharma Co Ltd Carbamoylsubstituiertes spiro-derivat
EP2069355A4 (en) * 2006-07-19 2010-03-24 Astrazeneca Ab NOVEL TRICYCLIC SPIROPIPERIDINE COMPOUNDS, THEIR SYNTHESIS AND THEIR USE AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
EP2072519A4 (en) * 2006-09-28 2009-10-21 Banyu Pharma Co Ltd DIARYLKETIMINDERIVAT
WO2008080844A1 (en) * 2006-12-29 2008-07-10 F. Hoffmann-La Roche Ag Azaspiro derivatives
JP2010524932A (ja) * 2007-04-16 2010-07-22 アムジエン・インコーポレーテツド 置換ビフェニルフェノキシ−、チオフェニル−及びアミノフェニルプロパン酸ｇｐｒ４０調節物質
AU2008314933B2 (en) 2007-10-26 2013-05-02 Japan Tobacco Inc. Spiro-ring compound and use thereof for medical purposes
AR078522A1 (es) 2009-10-15 2011-11-16 Lilly Co Eli Compuesto de espiropiperidina, composicion farmaceutica que lo comprende, su uso para preparar un medicamento util para tratar diabetes y compuesto intermediario para su sintesis
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament

Also Published As

Publication number Publication date
BR112012012903A2 (pt) 2017-03-01
CN102648195A (zh) 2012-08-22
JP5709889B2 (ja) 2015-04-30
KR20120088770A (ko) 2012-08-08
TW201141866A (en) 2011-12-01
CR20120296A (es) 2012-07-16
PE20121474A1 (es) 2012-11-05
MX2012006233A (es) 2012-07-03
JP2013512277A (ja) 2013-04-11
ECSP12011930A (es) 2012-07-31
AU2010324987A1 (en) 2012-07-26
CA2781292C (en) 2014-04-22
US20120220616A1 (en) 2012-08-30
ES2526568T3 (es) 2015-01-13
EP2507228A1 (en) 2012-10-10
CA2781292A1 (en) 2011-06-03
KR101410103B1 (ko) 2014-06-25
TN2012000248A1 (en) 2013-12-12
MA33840B1 (fr) 2012-12-03
CN102648195B (zh) 2015-01-07
EA020507B1 (ru) 2014-11-28
CL2012001321A1 (es) 2013-11-15
EA201290416A1 (ru) 2012-11-30
AU2010324987B2 (en) 2014-01-30
AR078948A1 (es) 2011-12-14
EP2507228B1 (en) 2014-11-05
WO2011066183A1 (en) 2011-06-03
IL219594A0 (en) 2012-06-28
ZA201203055B (en) 2013-09-25
DOP2012000139A (es) 2012-08-15
NZ600203A (en) 2013-09-27
US8822486B2 (en) 2014-09-02

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