SI2049513T1 - Piperidinil substituirani pirolidinoni kot inhibitorji 11-betahidroksisteroid dehidrogenaze 1 - Google Patents
Piperidinil substituirani pirolidinoni kot inhibitorji 11-betahidroksisteroid dehidrogenaze 1Info
- Publication number
- SI2049513T1 SI2049513T1 SI200730872T SI200730872T SI2049513T1 SI 2049513 T1 SI2049513 T1 SI 2049513T1 SI 200730872 T SI200730872 T SI 200730872T SI 200730872 T SI200730872 T SI 200730872T SI 2049513 T1 SI2049513 T1 SI 2049513T1
- Authority
- SI
- Slovenia
- Prior art keywords
- inhibitors
- beta
- compounds
- hydroxysteroid dehydrogenase
- piperidinyl substituted
- Prior art date
Links
- 102100036506 11-beta-hydroxysteroid dehydrogenase 1 Human genes 0.000 title 1
- 101710186107 11-beta-hydroxysteroid dehydrogenase 1 Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 125000003386 piperidinyl group Chemical group 0.000 title 1
- 150000004040 pyrrolidinones Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 230000000694 effects Effects 0.000 abstract 2
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 208000001145 Metabolic Syndrome Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 201000001421 hyperglycemia Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Gynecology & Obstetrics (AREA)
- Child & Adolescent Psychology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Enzymes And Modification Thereof (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79611206P | 2006-04-28 | 2006-04-28 | |
| PCT/US2007/067597 WO2007127901A1 (en) | 2006-04-28 | 2007-04-27 | Pieridinyl substituted pyrrolidinones as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
| EP07761424A EP2049513B1 (en) | 2006-04-28 | 2007-04-27 | Piperidinyl substituted pyrrolidinones as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2049513T1 true SI2049513T1 (sl) | 2012-04-30 |
Family
ID=38421166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200730872T SI2049513T1 (sl) | 2006-04-28 | 2007-04-27 | Piperidinil substituirani pirolidinoni kot inhibitorji 11-betahidroksisteroid dehidrogenaze 1 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7829582B2 (sl) |
| EP (1) | EP2049513B1 (sl) |
| JP (1) | JP5225980B2 (sl) |
| KR (1) | KR101060016B1 (sl) |
| CN (1) | CN101448816B (sl) |
| AT (1) | ATE542811T1 (sl) |
| AU (1) | AU2007244742B2 (sl) |
| BR (1) | BRPI0710469A2 (sl) |
| CA (1) | CA2650627C (sl) |
| CY (1) | CY1112466T1 (sl) |
| DK (1) | DK2049513T3 (sl) |
| EA (1) | EA014719B1 (sl) |
| EC (1) | ECSP088849A (sl) |
| IL (1) | IL194879A0 (sl) |
| MA (1) | MA30421B1 (sl) |
| MX (1) | MX2008013844A (sl) |
| NO (1) | NO20084874L (sl) |
| PL (1) | PL2049513T3 (sl) |
| PT (1) | PT2049513E (sl) |
| SI (1) | SI2049513T1 (sl) |
| TN (1) | TNSN08432A1 (sl) |
| WO (1) | WO2007127901A1 (sl) |
| ZA (1) | ZA200808816B (sl) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2533263T3 (es) * | 2006-04-21 | 2015-04-08 | Eli Lilly And Company | Derivados de ciclohexilpirazol-lactama como inhibidores de 11-beta-hidroxiesteroide deshidrogenasa 1 |
| EP2016047B1 (en) * | 2006-04-21 | 2013-08-28 | Eli Lilly And Company | Biphenyl amide lactam derivatives as inhibitors of 11- beta-hydroxysteroid dehydrogenase 1 |
| EP2029576B1 (en) | 2006-04-21 | 2013-06-19 | Eli Lilly & Company | Cyclohexylimidazole lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
| CA2649111C (en) | 2006-04-24 | 2013-09-10 | Eli Lilly And Company | Cyclohexyl substituted pyrrolidinones as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
| ATE473210T1 (de) | 2006-04-24 | 2010-07-15 | Lilly Co Eli | Substituierte pyrrolidinone als hemmer von 11- beta-hydroxysteroiddehydrogenase 1 |
| KR101059614B1 (ko) | 2006-04-24 | 2011-08-25 | 일라이 릴리 앤드 캄파니 | 11-베타-히드록시스테로이드 데히드로게나제 1의 억제제 |
| WO2007127765A1 (en) * | 2006-04-25 | 2007-11-08 | Eli Lilly And Company | Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
| US7968585B2 (en) | 2006-04-25 | 2011-06-28 | Eli Lilly And Company | Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
| PT2021337E (pt) | 2006-04-25 | 2010-02-22 | Lilly Co Eli | Inibidores de 11-beta-hidroxisteróide-desidrogenase 1 |
| EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| EP2243479A3 (en) | 2009-04-20 | 2011-01-19 | Abbott Laboratories | Novel amide and amidine derivates and uses thereof |
| US8871208B2 (en) * | 2009-12-04 | 2014-10-28 | Abbvie Inc. | 11-β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors and uses thereof |
| WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| EP2582709B1 (de) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| US8828994B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
| US8871758B2 (en) | 2011-03-08 | 2014-10-28 | Sanofi | Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof |
| US8828995B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
| US8710050B2 (en) | 2011-03-08 | 2014-04-29 | Sanofi | Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
| EP2766349B1 (de) | 2011-03-08 | 2016-06-01 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| EP2760862B1 (en) | 2011-09-27 | 2015-10-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| KR101593493B1 (ko) | 2014-10-28 | 2016-02-18 | 주식회사 아이에스티이 | 대면적 유리기판 열처리 장치 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003269242A1 (en) * | 2002-10-11 | 2004-05-04 | Astrazeneca Ab | 1,4-disubstituted piperidine derivatives and their use as 11-betahsd1 inhibitors |
| WO2004056744A1 (en) | 2002-12-23 | 2004-07-08 | Janssen Pharmaceutica N.V. | Adamantyl acetamides as hydroxysteroid dehydrogenase inhibitors |
| ATE397586T1 (de) * | 2004-05-07 | 2008-06-15 | Janssen Pharmaceutica Nv | Adamantyl pyrrolidin-2-on-derivate als 11-beta hydroxysteroid dehydrogenas inhibitoren |
| JP5014983B2 (ja) * | 2004-05-07 | 2012-08-29 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | １１−ベータヒドロキシステロイドデヒドロゲナーゼ阻害剤としてのピロリジン−２−オン及びピペリジン−２−オン誘導体 |
| JP2008515956A (ja) | 2004-10-12 | 2008-05-15 | ノボ ノルディスク アクティーゼルスカブ | １１β−ヒドロキシステロイドデヒドロゲナーゼ１型活性スピロ化合物 |
| EP1807072B1 (en) * | 2004-10-29 | 2009-01-07 | Eli Lilly And Company | Cycloalkyl lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
| NZ554906A (en) | 2004-11-10 | 2011-01-28 | Incyte Corp | Lactam compounds and their use as pharmaceuticals |
| ATE399546T1 (de) | 2004-12-20 | 2008-07-15 | Lilly Co Eli | Cycloalkyl-lactam-derivate als inhibitoren von 11-beta-hydroxysteroiddehydrogenase 1 |
| ATE401073T1 (de) | 2004-12-21 | 2008-08-15 | Lilly Co Eli | Cycloalkyl-lactam-derivate als inhibitoren von 11-beta-hydroxysteroiddehydrogenase 1 |
| WO2006104280A1 (ja) | 2005-03-31 | 2006-10-05 | Takeda Pharmaceutical Company Limited | 糖尿病の予防・治療剤 |
| WO2007084314A2 (en) | 2006-01-12 | 2007-07-26 | Incyte Corporation | MODULATORS OF 11-ß HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME |
| ES2533263T3 (es) | 2006-04-21 | 2015-04-08 | Eli Lilly And Company | Derivados de ciclohexilpirazol-lactama como inhibidores de 11-beta-hidroxiesteroide deshidrogenasa 1 |
| EP2029576B1 (en) | 2006-04-21 | 2013-06-19 | Eli Lilly & Company | Cyclohexylimidazole lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
| EP2016047B1 (en) | 2006-04-21 | 2013-08-28 | Eli Lilly And Company | Biphenyl amide lactam derivatives as inhibitors of 11- beta-hydroxysteroid dehydrogenase 1 |
| KR101059614B1 (ko) | 2006-04-24 | 2011-08-25 | 일라이 릴리 앤드 캄파니 | 11-베타-히드록시스테로이드 데히드로게나제 1의 억제제 |
| CA2649111C (en) | 2006-04-24 | 2013-09-10 | Eli Lilly And Company | Cyclohexyl substituted pyrrolidinones as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
| ATE473210T1 (de) | 2006-04-24 | 2010-07-15 | Lilly Co Eli | Substituierte pyrrolidinone als hemmer von 11- beta-hydroxysteroiddehydrogenase 1 |
| US7968585B2 (en) | 2006-04-25 | 2011-06-28 | Eli Lilly And Company | Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
| WO2007127765A1 (en) | 2006-04-25 | 2007-11-08 | Eli Lilly And Company | Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
| PT2021337E (pt) | 2006-04-25 | 2010-02-22 | Lilly Co Eli | Inibidores de 11-beta-hidroxisteróide-desidrogenase 1 |
| CL2008001839A1 (es) | 2007-06-21 | 2009-01-16 | Incyte Holdings Corp | Compuestos derivados de 2,7-diazaespirociclos, inhibidores de 11-beta hidroxil esteroide deshidrogenasa tipo 1; composicion farmaceutica que comprende a dichos compuestos; utiles para tratar la obesidad, diabetes, intolerancia a la glucosa, diabetes tipo ii, entre otras enfermedades. |
-
2007
- 2007-04-27 US US12/297,951 patent/US7829582B2/en not_active Expired - Fee Related
- 2007-04-27 CN CN2007800154205A patent/CN101448816B/zh not_active Expired - Fee Related
- 2007-04-27 BR BRPI0710469-3A patent/BRPI0710469A2/pt not_active IP Right Cessation
- 2007-04-27 KR KR1020087026195A patent/KR101060016B1/ko not_active IP Right Cessation
- 2007-04-27 MX MX2008013844A patent/MX2008013844A/es active IP Right Grant
- 2007-04-27 AT AT07761424T patent/ATE542811T1/de active
- 2007-04-27 PL PL07761424T patent/PL2049513T3/pl unknown
- 2007-04-27 PT PT07761424T patent/PT2049513E/pt unknown
- 2007-04-27 WO PCT/US2007/067597 patent/WO2007127901A1/en active Application Filing
- 2007-04-27 JP JP2009507978A patent/JP5225980B2/ja not_active Expired - Fee Related
- 2007-04-27 EP EP07761424A patent/EP2049513B1/en active Active
- 2007-04-27 AU AU2007244742A patent/AU2007244742B2/en not_active Ceased
- 2007-04-27 CA CA2650627A patent/CA2650627C/en not_active Expired - Fee Related
- 2007-04-27 EA EA200870489A patent/EA014719B1/ru not_active IP Right Cessation
- 2007-04-27 SI SI200730872T patent/SI2049513T1/sl unknown
- 2007-04-27 DK DK07761424.6T patent/DK2049513T3/da active
-
2008
- 2008-10-15 ZA ZA200808816A patent/ZA200808816B/xx unknown
- 2008-10-23 IL IL194879A patent/IL194879A0/en unknown
- 2008-10-24 TN TNP2008000432A patent/TNSN08432A1/en unknown
- 2008-10-27 EC EC2008008849A patent/ECSP088849A/es unknown
- 2008-11-19 NO NO20084874A patent/NO20084874L/no not_active Application Discontinuation
- 2008-11-20 MA MA31397A patent/MA30421B1/fr unknown
-
2012
- 2012-03-08 CY CY20121100235T patent/CY1112466T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TNSN08432A1 (en) | 2010-04-14 |
| ECSP088849A (es) | 2008-11-27 |
| EP2049513A1 (en) | 2009-04-22 |
| US20090088430A1 (en) | 2009-04-02 |
| CN101448816A (zh) | 2009-06-03 |
| IL194879A0 (en) | 2009-08-03 |
| EA200870489A1 (ru) | 2009-04-28 |
| AU2007244742A1 (en) | 2007-11-08 |
| WO2007127901A1 (en) | 2007-11-08 |
| US7829582B2 (en) | 2010-11-09 |
| MX2008013844A (es) | 2008-11-10 |
| JP2009535362A (ja) | 2009-10-01 |
| EP2049513B1 (en) | 2012-01-25 |
| CY1112466T1 (el) | 2015-12-09 |
| EA014719B1 (ru) | 2011-02-28 |
| MA30421B1 (fr) | 2009-05-04 |
| KR101060016B1 (ko) | 2011-08-29 |
| PT2049513E (pt) | 2012-03-20 |
| CA2650627C (en) | 2013-07-16 |
| DK2049513T3 (da) | 2012-02-27 |
| NO20084874L (no) | 2008-11-19 |
| ATE542811T1 (de) | 2012-02-15 |
| BRPI0710469A2 (pt) | 2011-08-16 |
| AU2007244742B2 (en) | 2012-03-08 |
| CA2650627A1 (en) | 2007-11-08 |
| JP5225980B2 (ja) | 2013-07-03 |
| PL2049513T3 (pl) | 2012-06-29 |
| ZA200808816B (en) | 2009-12-30 |
| KR20090007371A (ko) | 2009-01-16 |
| CN101448816B (zh) | 2013-08-07 |
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| Publication | Publication Date | Title |
|---|---|---|
| PL2049513T3 (pl) | Pirolidynony podstawione przez piperydynyl jako inhibitory dehydrogenazy 11-beta-hydroksysteroidowej typu 1 | |
| PL2049475T3 (pl) | Pirolidynony podstawione cykloheksylem jako inhibitory 11-betahydrokysterydu dehydrogenazy 1 | |
| UA95798C2 (ru) | Производные циклогексилпиразоллактама как ингибиторы 11-бета-гидроксистероиддегидрогеназы 1 | |
| PL2029529T3 (pl) | PODSTAWIONE PIROLIDYNONY JAKO INHIBITORY DEHYDROGENAZY 11-ß-HYDROKSYSTEROIDOWEJ TYPU 1 | |
| PL2021337T3 (pl) | Inhibitory dehydrogenazy 11-beta-hydroksysteroidowej typu 1 | |
| ATE471311T1 (de) | Inhibitoren von11-beta- hydroxysteroiddehydrogenase 1 | |
| MY148079A (en) | Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 | |
| PL1807072T3 (pl) | Cykloalkilowe pochodne laktamów jako inhibitory 11-ß-HSD1 |