SI1954710T1 - Pospeĺ evala za modifikacijo nenaravnih aminokislin in nenaravnih peptidov aminokislin - Google Patents

Pospeĺ evala za modifikacijo nenaravnih aminokislin in nenaravnih peptidov aminokislin

Info

Publication number
SI1954710T1
SI1954710T1 SI200631022T SI200631022T SI1954710T1 SI 1954710 T1 SI1954710 T1 SI 1954710T1 SI 200631022 T SI200631022 T SI 200631022T SI 200631022 T SI200631022 T SI 200631022T SI 1954710 T1 SI1954710 T1 SI 1954710T1
Authority
SI
Slovenia
Prior art keywords
natural amino
accelerants
amino acid
modification
acid polypeptides
Prior art date
Application number
SI200631022T
Other languages
English (en)
Inventor
Feng Tian
Zhenwei Miao
Original Assignee
Ambrx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ambrx Inc filed Critical Ambrx Inc
Publication of SI1954710T1 publication Critical patent/SI1954710T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SI200631022T 2005-11-08 2006-11-08 Pospeĺ evala za modifikacijo nenaravnih aminokislin in nenaravnih peptidov aminokislin SI1954710T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73458905P 2005-11-08 2005-11-08
EP06837144A EP1954710B1 (en) 2005-11-08 2006-11-08 Accelerants for the modification of non-natural amino acids and non-natural amino acid polypeptides
PCT/US2006/043472 WO2007056448A2 (en) 2005-11-08 2006-11-08 Accelerants for the modification of non-natural amino acids and non-natural amino acid polypeptides

Publications (1)

Publication Number Publication Date
SI1954710T1 true SI1954710T1 (sl) 2011-08-31

Family

ID=38023955

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200631022T SI1954710T1 (sl) 2005-11-08 2006-11-08 Pospeĺ evala za modifikacijo nenaravnih aminokislin in nenaravnih peptidov aminokislin

Country Status (21)

Country Link
US (5) US20090137736A1 (sl)
EP (1) EP1954710B1 (sl)
JP (1) JP5508716B2 (sl)
KR (1) KR101379071B1 (sl)
CN (2) CN104710503B (sl)
AT (1) ATE500215T1 (sl)
AU (1) AU2006311568B2 (sl)
CA (1) CA2625540C (sl)
CY (1) CY1111506T1 (sl)
DE (1) DE602006020480D1 (sl)
DK (1) DK1954710T3 (sl)
ES (1) ES2362373T3 (sl)
HK (1) HK1123310A1 (sl)
HR (1) HRP20110404T1 (sl)
IL (1) IL190694A (sl)
NZ (1) NZ567234A (sl)
PL (1) PL1954710T3 (sl)
PT (1) PT1954710E (sl)
RS (1) RS51998B (sl)
SI (1) SI1954710T1 (sl)
WO (1) WO2007056448A2 (sl)

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EP1968635B1 (en) 2005-12-14 2014-09-17 Ambrx, Inc. Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
US20090286968A1 (en) * 2008-04-25 2009-11-19 Auburn University 2-Quinoxalinol Salen Compounds and Uses Thereof
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WO2011109326A2 (en) * 2010-03-02 2011-09-09 Yumei Huang Crosslinking reagents, methods, and compositions for studying protein-protein interactions
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US9567386B2 (en) 2010-08-17 2017-02-14 Ambrx, Inc. Therapeutic uses of modified relaxin polypeptides
RU2606016C2 (ru) 2011-01-14 2017-01-10 Редвуд Байосайнс, Инк. Меченые альдегидом полипептиды иммуноглобулина и способы их применения
CA2837586C (en) * 2011-05-27 2018-12-11 Ambrx, Inc. Compositions containing, methods involving, and uses of non-natural amino acid linked dolastatin derivatives
WO2012166559A1 (en) * 2011-05-27 2012-12-06 Ambrx, Inc. Compositions containing, methods involving, and uses of non-natural amino acid linked dolastatin derivatives
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CA2978617A1 (en) 2015-03-06 2016-09-15 Canimguide Therapeutics Ab Immune system modulators and compositions
DK3283508T3 (en) 2015-04-17 2021-05-31 Alpine Immune Sciences Inc Immunomodulatory Proteins with Tunable Affinities
ES2827776T3 (es) 2015-11-23 2021-05-24 Bristol Myers Squibb Co Sistemas de aditivos para uso en la PEGilación de proteínas
CN109071634A (zh) 2016-04-26 2018-12-21 R.P.谢勒技术有限责任公司 抗体偶联物及其制备和使用方法
CN110637027A (zh) 2017-02-08 2019-12-31 百时美施贵宝公司 包含药代动力学增强子的修饰的松弛素多肽及其用途
US20220056093A1 (en) * 2018-09-11 2022-02-24 Ambrx, Inc. Interleukin-2 polypeptide conjugates and their uses
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US20080139793A1 (en) 2008-06-12
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AU2006311568A1 (en) 2007-05-18
CA2625540A1 (en) 2007-05-18
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CA2625540C (en) 2017-03-21
DK1954710T3 (da) 2011-06-27
KR20080075498A (ko) 2008-08-18
US20090137736A1 (en) 2009-05-28
IL190694A0 (en) 2008-11-03
CN101400646A (zh) 2009-04-01
WO2007056448A3 (en) 2009-05-14
US20080139794A1 (en) 2008-06-12
US8071809B2 (en) 2011-12-06
IL190694A (en) 2016-05-31
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EP1954710A2 (en) 2008-08-13
AU2006311568B2 (en) 2010-11-11
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EP1954710B1 (en) 2011-03-02
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US20080154058A1 (en) 2008-06-26
KR101379071B1 (ko) 2014-03-28
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