SI1888537T1 - Postopek priprave 4-((1,6-dihidro-6-okso-2-pirimidinil)amino benzonitrila - Google Patents

Postopek priprave 4-((1,6-dihidro-6-okso-2-pirimidinil)amino benzonitrila

Info

Publication number
SI1888537T1
SI1888537T1 SI200631704T SI200631704T SI1888537T1 SI 1888537 T1 SI1888537 T1 SI 1888537T1 SI 200631704 T SI200631704 T SI 200631704T SI 200631704 T SI200631704 T SI 200631704T SI 1888537 T1 SI1888537 T1 SI 1888537T1
Authority
SI
Slovenia
Prior art keywords
pyrimidinyl
dihydro
oxo
preparing
amino benzonitrile
Prior art date
Application number
SI200631704T
Other languages
English (en)
Slovenian (sl)
Inventor
Didier Philippe Robert Schils
Alfred Elisabeth Stappers
Original Assignee
Janssen R&D Ireland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35822492&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1888537(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen R&D Ireland filed Critical Janssen R&D Ireland
Publication of SI1888537T1 publication Critical patent/SI1888537T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SI200631704T 2005-05-26 2006-05-24 Postopek priprave 4-((1,6-dihidro-6-okso-2-pirimidinil)amino benzonitrila SI1888537T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP05104531 2005-05-26
US68599305P 2005-05-31 2005-05-31
PCT/EP2006/062606 WO2006125809A1 (en) 2005-05-26 2006-05-24 Process for preparing 4-[(1,6-dihydro-6-oxo-2-pyrimidinyl)amino benzonitrile
EP06755299.2A EP1888537B1 (en) 2005-05-26 2006-05-24 Process for preparing 4-[(1,6-dihydro-6-oxo-2-pyrimidinyl)amino benzonitrile

Publications (1)

Publication Number Publication Date
SI1888537T1 true SI1888537T1 (sl) 2014-01-31

Family

ID=35822492

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200631704T SI1888537T1 (sl) 2005-05-26 2006-05-24 Postopek priprave 4-((1,6-dihidro-6-okso-2-pirimidinil)amino benzonitrila

Country Status (19)

Country Link
US (2) US8101752B2 (https=)
EP (1) EP1888537B1 (https=)
JP (2) JP5148483B2 (https=)
CN (1) CN101248051B (https=)
AU (1) AU2006251163C1 (https=)
BR (1) BRPI0611038B8 (https=)
CA (1) CA2609716C (https=)
DK (1) DK1888537T3 (https=)
ES (1) ES2437202T3 (https=)
HR (1) HRP20131133T1 (https=)
IN (1) IN2014DN04588A (https=)
ME (1) ME01612B (https=)
MX (1) MX2007014881A (https=)
PL (1) PL1888537T3 (https=)
PT (1) PT1888537E (https=)
RS (1) RS53062B (https=)
RU (1) RU2458056C2 (https=)
SI (1) SI1888537T1 (https=)
WO (1) WO2006125809A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007014881A (es) * 2005-05-26 2008-02-15 Tibotec Pharm Ltd Procedimiento para preparar 4-(1,6-dihidro-6-oxo-2-pirimidinil) amino benzonitrilo.
WO2012125993A1 (en) 2011-03-17 2012-09-20 Teva Pharmaceutical Industries Ltd. Solid state forms of rilpivirine base, and rilipivirine salts
MX351340B (es) 2012-03-13 2017-10-11 Octapharma Ag Proceso mejorado para la produccion de fibrinogeno y fibrinogeno producido por este.
CN103058936B (zh) * 2013-01-23 2016-01-06 宁波九胜创新医药科技有限公司 4-[(4-氯-2-嘧啶基)氨基]苯腈的制备方法
CN103193719B (zh) * 2013-04-08 2015-07-22 宁波九胜创新医药科技有限公司 一种4-[(4-羟基-2-嘧啶基)氨基]苯腈的制备方法
CN114933567B (zh) * 2022-04-29 2023-07-11 武汉工程大学 一种2-甲硫基-4-嘧啶酮的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE63502B1 (en) * 1989-04-21 1995-05-03 Zeneca Ltd Aminopyrimidine derivatives useful for treating cardiovascular disorders
DE3923979A1 (de) 1989-07-20 1991-01-24 Merck Patent Gmbh Verfahren zur herstellung von aromatischen nitrilen
RU2037483C1 (ru) * 1989-07-20 1995-06-19 Мерк Патент Гмбх Способ получения замещенных ароматических нитрилов
EA002973B1 (ru) * 1998-03-27 2002-12-26 Янссен Фармацевтика Н.В. Производные пиримидина в качестве ингибиторов репликации вируса иммунодефицита человека
SK287270B6 (sk) * 1998-11-10 2010-05-07 Janssen Pharmaceutica N. V. Derivát pyrimidínu
TR200200763T2 (tr) * 1999-09-24 2003-09-22 Janssen Pharmaceutica N.V. Antiviral bileşimler
AU782948B2 (en) * 2000-05-08 2005-09-15 Janssen Pharmaceutica N.V. Prodrugs of HIV replication inhibiting pyrimidines
JO3429B1 (ar) * 2001-08-13 2019-10-20 Janssen Pharmaceutica Nv مشتقات برميدينات مثبطة فيروس الايدز
HUP0402106A3 (en) * 2001-11-01 2009-07-28 Janssen Pharmaceutica Nv Heteroaryl amines as glycogen synthase kinase 3 beta inhibitors, process for their preparation and pharmaceutical compositions containing them
DK1529032T3 (da) * 2002-08-09 2013-07-08 Janssen Pharmaceutica Nv Fremgangsmåder til fremstilling af 4-4-4-(2-cyanoethenyl)-2,6-dimethylphenyl)amino)-2-pyrimidinyl)aminobenzonitrill
RU2006110561A (ru) * 2003-09-30 2007-10-10 Янссен Фармацевтика Н.В. (Be) Соединения бензоимидазола
MX2007014881A (es) * 2005-05-26 2008-02-15 Tibotec Pharm Ltd Procedimiento para preparar 4-(1,6-dihidro-6-oxo-2-pirimidinil) amino benzonitrilo.

Also Published As

Publication number Publication date
US20080171878A1 (en) 2008-07-17
CN101248051A (zh) 2008-08-20
MX2007014881A (es) 2008-02-15
BRPI0611038B8 (pt) 2022-10-25
JP5148483B2 (ja) 2013-02-20
RU2458056C2 (ru) 2012-08-10
HK1123551A1 (en) 2009-06-19
PT1888537E (pt) 2013-11-26
CN101248051B (zh) 2013-07-17
US8618291B2 (en) 2013-12-31
ME01612B (me) 2014-09-20
HRP20131133T1 (hr) 2014-01-03
BRPI0611038B1 (pt) 2022-02-08
DK1888537T3 (da) 2013-12-09
ES2437202T3 (es) 2014-01-09
EP1888537B1 (en) 2013-09-11
CA2609716A1 (en) 2006-11-30
WO2006125809A1 (en) 2006-11-30
JP2008545680A (ja) 2008-12-18
BRPI0611038A2 (pt) 2010-08-10
IN2014DN04588A (https=) 2015-07-10
JP5580385B2 (ja) 2014-08-27
AU2006251163A1 (en) 2006-11-30
EP1888537A1 (en) 2008-02-20
RU2007148968A (ru) 2009-07-10
AU2006251163B2 (en) 2012-03-08
JP2013040194A (ja) 2013-02-28
US8101752B2 (en) 2012-01-24
US20120083606A1 (en) 2012-04-05
RS53062B (sr) 2014-04-30
CA2609716C (en) 2014-10-14
PL1888537T3 (pl) 2014-02-28
AU2006251163C1 (en) 2012-07-12

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