SI1731138T1 - Fina disperzija slabo topljivega zdravila in postopek za njeno izdelavo - Google Patents

Fina disperzija slabo topljivega zdravila in postopek za njeno izdelavo

Info

Publication number
SI1731138T1
SI1731138T1 SI200532064A SI200532064A SI1731138T1 SI 1731138 T1 SI1731138 T1 SI 1731138T1 SI 200532064 A SI200532064 A SI 200532064A SI 200532064 A SI200532064 A SI 200532064A SI 1731138 T1 SI1731138 T1 SI 1731138T1
Authority
SI
Slovenia
Prior art keywords
producing
same
sparingly soluble
soluble drug
fine dispersion
Prior art date
Application number
SI200532064A
Other languages
English (en)
Inventor
Yoshiko Kubo
Tetsumi Yamakawa
Yasuomi Yamasaki
Original Assignee
Toyama Chemical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co., Ltd. filed Critical Toyama Chemical Co., Ltd.
Publication of SI1731138T1 publication Critical patent/SI1731138T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SI200532064A 2004-03-31 2005-03-28 Fina disperzija slabo topljivega zdravila in postopek za njeno izdelavo SI1731138T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2004102780 2004-03-31
EP05727436.7A EP1731138B1 (en) 2004-03-31 2005-03-28 Fine dispersion of sparingly soluble drug and process for producing the same
PCT/JP2005/005736 WO2005094788A1 (ja) 2004-03-31 2005-03-28 難溶性薬物の微粒子分散液およびその製造方法

Publications (1)

Publication Number Publication Date
SI1731138T1 true SI1731138T1 (sl) 2016-06-30

Family

ID=35063485

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200532064A SI1731138T1 (sl) 2004-03-31 2005-03-28 Fina disperzija slabo topljivega zdravila in postopek za njeno izdelavo

Country Status (9)

Country Link
EP (1) EP1731138B1 (sl)
JP (1) JP4875979B2 (sl)
CY (1) CY1118548T1 (sl)
DK (1) DK1731138T3 (sl)
ES (1) ES2566486T3 (sl)
HU (1) HUE028288T2 (sl)
PL (1) PL1731138T3 (sl)
SI (1) SI1731138T1 (sl)
WO (1) WO2005094788A1 (sl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2615912C (en) 2005-08-01 2013-10-01 Maruho Co., Ltd. Lotion preparation containing pyridonecarboxylic acid derivative
CN1931159B (zh) * 2005-09-16 2010-05-12 天津药物研究院 艾拉莫德微粉化及口服速释制剂
CN101375834B (zh) * 2007-09-02 2012-07-04 杨喜鸿 艾拉莫德的固体分散体及其制备方法和药物应用
JP5428058B2 (ja) * 2007-12-28 2014-02-26 ライオン株式会社 微粒化エラグ酸化合物の製造方法
EP2177209A1 (en) 2008-10-17 2010-04-21 Ferrer Internacional, S.A. Intravenous solutions and uses
EP2177208A1 (en) 2008-10-17 2010-04-21 Ferrer Internacional, S.A. Pharmaceutical topical compositions
EP2177214A1 (en) 2008-10-17 2010-04-21 Ferrer Internacional, S.A. Solid Oral Dosage Forms and Uses
EP2556063B1 (en) 2010-04-06 2015-07-01 Ferrer Internacional, S.A. 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)-3-pyridinyl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid salts
PT105058B (pt) 2010-04-21 2013-04-17 Hovione Farmaciencia S A Processo para processamento de partículas de ingredientes activos farmacêuticos
CN103110578B (zh) * 2013-02-05 2014-11-12 广东华南药业集团有限公司 一种灯盏花素磷脂复合物自微乳组合物及其制备方法
JP5799061B2 (ja) * 2013-08-23 2015-10-21 富山化学工業株式会社 トスフロキサシンおよびポリビニルピロリドンを含有する粒状固形製剤
JP5799062B2 (ja) * 2013-08-23 2015-10-21 富山化学工業株式会社 トスフロキサシンを含有する粒状固形製剤
JP2015166387A (ja) * 2015-06-08 2015-09-24 フエルレル インターナショナル，ソシエダッド アノニマ １‐シクロプロピル‐８‐メチル‐７‐［５‐メチル‐６‐（メチルアミノ）‐３‐ピリジニル］‐４‐オキソ‐１，４‐ジヒドロ‐３‐キノリンカルボン酸塩

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5145684A (en) * 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
JP2554784B2 (ja) * 1991-03-15 1996-11-13 杏林製薬株式会社 懸濁シロップ剤
US5298262A (en) * 1992-12-04 1994-03-29 Sterling Winthrop Inc. Use of ionic cloud point modifiers to prevent particle aggregation during sterilization
US5510118A (en) * 1995-02-14 1996-04-23 Nanosystems Llc Process for preparing therapeutic compositions containing nanoparticles
CA2335472C (en) * 1998-06-19 2008-10-28 Rtp Pharma Inc. Processes to generate submicron particles of water-insoluble compounds
JP2003026676A (ja) * 2000-12-11 2003-01-29 Takeda Chem Ind Ltd 吸収性が改善された医薬組成物
WO2002055059A2 (en) * 2000-12-22 2002-07-18 Baxter Int Method for preparing submicron particle suspensions
US20040258757A1 (en) * 2002-07-16 2004-12-23 Elan Pharma International, Ltd. Liquid dosage compositions of stable nanoparticulate active agents

Also Published As

Publication number Publication date
EP1731138A1 (en) 2006-12-13
JPWO2005094788A1 (ja) 2008-02-14
HUE028288T2 (en) 2016-12-28
ES2566486T3 (es) 2016-04-13
EP1731138B1 (en) 2016-03-23
EP1731138A4 (en) 2012-04-25
PL1731138T3 (pl) 2016-10-31
CY1118548T1 (el) 2017-07-12
DK1731138T3 (en) 2016-06-06
JP4875979B2 (ja) 2012-02-15
WO2005094788A1 (ja) 2005-10-13

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