SI1572153T1 - Priprava sterilnih vodnih suspenzij ki vsebujejomikrokristalne učinkovite sestavine za inhalacijo - Google Patents

Priprava sterilnih vodnih suspenzij ki vsebujejomikrokristalne učinkovite sestavine za inhalacijo

Info

Publication number
SI1572153T1
SI1572153T1 SI200332125T SI200332125T SI1572153T1 SI 1572153 T1 SI1572153 T1 SI 1572153T1 SI 200332125 T SI200332125 T SI 200332125T SI 200332125 T SI200332125 T SI 200332125T SI 1572153 T1 SI1572153 T1 SI 1572153T1
Authority
SI
Slovenia
Prior art keywords
preparation
active ingredients
sterile aqueous
aqueous suspensions
inhalation
Prior art date
Application number
SI200332125T
Other languages
English (en)
Inventor
Andrea Capocchi
Fausto Pivetti
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of SI1572153T1 publication Critical patent/SI1572153T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0017—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00—Treatment of water, waste water, or sewage
    • C02F1/68—Treatment of water, waste water, or sewage by addition of specified substances, e.g. trace elements, for ameliorating potable water
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F2103/00—Nature of the water, waste water, sewage or sludge to be treated
    • C02F2103/02—Non-contaminated water, e.g. for industrial water supply
    • C02F2103/026—Treating water for medical or cosmetic purposes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Otolaryngology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
SI200332125T 2002-12-18 2003-12-17 Priprava sterilnih vodnih suspenzij ki vsebujejomikrokristalne učinkovite sestavine za inhalacijo SI1572153T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT002674A ITMI20022674A1 (it) 2002-12-18 2002-12-18 Procedimento per la preparazione di formulazioni sterili a base di principi attivi farmaceutici cristallini micronizzati da somministrare come sospensioni acquose per inalazione.
PCT/EP2003/014386 WO2004054545A1 (en) 2002-12-18 2003-12-17 Preparation of sterile aqueous suspensions comprising micronised crystalline active ingredients for inhalation
EP03785852A EP1572153B1 (en) 2002-12-18 2003-12-17 Preparation of sterile aqueous suspensions comprising micronised crystalline active ingredients for inhalation

Publications (1)

Publication Number Publication Date
SI1572153T1 true SI1572153T1 (sl) 2012-05-31

Family

ID=32587870

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200332125T SI1572153T1 (sl) 2002-12-18 2003-12-17 Priprava sterilnih vodnih suspenzij ki vsebujejomikrokristalne učinkovite sestavine za inhalacijo

Country Status (23)

Country Link
US (1) US8128909B2 (sl)
EP (1) EP1572153B1 (sl)
CN (1) CN100398095C (sl)
AT (1) ATE544445T1 (sl)
AU (1) AU2003294879A1 (sl)
BR (1) BRPI0316908B8 (sl)
CA (1) CA2510263C (sl)
DK (1) DK1572153T3 (sl)
EA (1) EA008122B1 (sl)
ES (1) ES2379349T3 (sl)
HK (1) HK1088217A1 (sl)
HR (1) HRP20050546B1 (sl)
IT (1) ITMI20022674A1 (sl)
MA (1) MA27702A1 (sl)
ME (2) MEP35208A (sl)
MX (1) MXPA05006441A (sl)
PL (1) PL213704B1 (sl)
PT (1) PT1572153E (sl)
RS (1) RS52151B (sl)
SI (1) SI1572153T1 (sl)
UA (1) UA87655C2 (sl)
WO (1) WO2004054545A1 (sl)
ZA (1) ZA200504897B (sl)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9704186D0 (sv) 1997-11-14 1997-11-14 Astra Ab New composition of matter
ITMI20020808A1 (it) * 2002-04-17 2003-10-17 Chiesi Farma Spa Procedimento per la preparazione di una sospensione sterile di particelle di beclometasone dipropionato da somministrare per inalazione
US9808471B2 (en) * 2003-04-16 2017-11-07 Mylan Specialty Lp Nasal pharmaceutical formulations and methods of using the same
US7811606B2 (en) * 2003-04-16 2010-10-12 Dey, L.P. Nasal pharmaceutical formulations and methods of using the same
US8912174B2 (en) 2003-04-16 2014-12-16 Mylan Pharmaceuticals Inc. Formulations and methods for treating rhinosinusitis
ITMI20032054A1 (it) * 2003-10-22 2005-04-23 Monteres S R L Processo per la preparazione di sospensioni farmaceutiche da inalare.
PE20050941A1 (es) * 2003-12-16 2005-11-08 Nycomed Gmbh Suspensiones acuosas de ciclesonida para nebulizacion
EP1949891A1 (en) * 2004-10-12 2008-07-30 Generics (UK) Limited Process for the preparation of suspension aerosol formulations, wherein the particles are formed by precipitation inside an aerosol canister
AU2005293328B2 (en) 2004-10-12 2010-09-30 Generics (Uk) Limited Process for the preparation of suspension aerosol formulations, wherein the particles are formed by precipitation inside an aerosol canister
ES2388287T3 (es) 2005-01-20 2012-10-11 Eratech S.R.L. Procedimiento para la preparación de suspensiones concentradas de fármacos y kit correspondiente
EP1782797A1 (en) * 2005-11-02 2007-05-09 Pharmatex Italia Srl Process for the preparation of sterile powdered pharmaceutical compounds.
CA2683712A1 (en) * 2007-04-20 2009-01-15 Sun Pharmaceutical Industries Limited Pharmaceutical compositions
UA97286C2 (ru) 2007-07-31 2012-01-25 Оцука Фармасьютикал Ко., Лтд. Способ изготовления суспензии арипипразола и лиофилизированного состава
KR20100095587A (ko) * 2007-12-13 2010-08-31 노파르티스 아게 유기 화합물
GB0806873D0 (en) * 2008-04-16 2008-05-21 Breath Ltd Steroid nebuliser formulation
CN101618019B (zh) * 2008-07-01 2011-08-03 上海通用药业股份有限公司 一种醋酸曲安奈德微粒及其制备方法和药物组合物
BR112013016851B1 (pt) 2011-01-12 2021-08-31 Intervet International B.V Método para preparar uma composição farmacêutica que compreende partículas de uma droga
ES2612257T3 (es) 2011-05-03 2017-05-16 Chiesi Farmaceutici S.P.A. Formulación de suspensión mejorada de dipropionato de beclometasona para administración mediante inhalación
JP4954345B1 (ja) * 2011-07-06 2012-06-13 アピ株式会社 医薬品原薬の無菌化精製装置
EP3741772B1 (en) * 2012-05-08 2024-06-19 Nicox Ophthalmics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
DE102012221219B4 (de) * 2012-11-20 2014-05-28 Jesalis Pharma Gmbh Verfahren zur Vergrößerung der Partikelgröße kristalliner Wirkstoff-Mikropartikel
MY181647A (en) 2014-09-09 2020-12-30 Vectura Ltd Formulation comprising glycopyrrolate, method and apparatus
EP3153606B1 (fr) * 2015-10-09 2019-10-09 Bgh Procede pour cristalliser des clathrates hydrates, et procede de purification d'un liquide aqueux utilisant les clathrates hydrates ainsi cristallises
WO2024180569A1 (en) * 2023-03-01 2024-09-06 Ajaykumar Balraj Kanduri A synergistic aqueous nebulization suspension for management of infectious respiratory disorders and process of preparation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2107715B (en) * 1981-10-19 1985-11-13 Glaxo Group Ltd Micronised beclomethasone dipropionate monohydrate and powder inhalation compositions containing it
US6187765B1 (en) * 1997-10-09 2001-02-13 Schering Corporation Mometasone furoate suspensions for nebulization
MA26621A1 (fr) * 1998-04-18 2004-12-20 Glaxo Group Ltd Composition pour aerosols pharmaceutiques
US6241969B1 (en) * 1998-06-26 2001-06-05 Elan Corporation Plc Aqueous compositions containing corticosteroids for nasal and pulmonary delivery
IT1303692B1 (it) * 1998-11-03 2001-02-23 Chiesi Farma Spa Procedimento per la preparazione di sospensioni di particelle difarmaci da somministrare per inalazione.
GB0015981D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
GB0016040D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
WO2003070285A1 (en) * 2002-02-19 2003-08-28 Resolution Chemicals Limited Solvent-based sterilisation of pharmaceuticals

Also Published As

Publication number Publication date
ATE544445T1 (de) 2012-02-15
PL377345A1 (pl) 2006-01-23
HRP20050546B1 (hr) 2014-05-23
MEP35208A (en) 2011-02-10
EA008122B1 (ru) 2007-04-27
AU2003294879A1 (en) 2004-07-09
WO2004054545A1 (en) 2004-07-01
CN1735403A (zh) 2006-02-15
EP1572153B1 (en) 2012-02-08
ITMI20022674A1 (it) 2004-06-19
PT1572153E (pt) 2012-03-22
ZA200504897B (en) 2006-09-27
CN100398095C (zh) 2008-07-02
BRPI0316908B1 (pt) 2016-01-26
BR0316908A (pt) 2005-10-18
MA27702A1 (fr) 2006-01-02
UA87655C2 (ru) 2009-08-10
EA200500833A1 (ru) 2006-02-24
BRPI0316908B8 (pt) 2021-05-25
CA2510263C (en) 2012-07-03
HRP20050546A2 (en) 2005-10-31
EP1572153A1 (en) 2005-09-14
RS52151B (en) 2012-08-31
US20070140980A1 (en) 2007-06-21
RS72504A (en) 2006-10-27
CA2510263A1 (en) 2004-07-01
ME01084B (me) 2011-05-10
ES2379349T3 (es) 2012-04-25
MXPA05006441A (es) 2005-09-08
PL213704B1 (pl) 2013-04-30
DK1572153T3 (da) 2012-03-05
HK1088217A1 (en) 2006-11-03
US8128909B2 (en) 2012-03-06

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