SI1259507T1 - Pseudopolymorph of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8 4r-(3s-hydroxy-1-methyl)piperidinyl)-4h-1-benzopyran-4-one hydrochloride - Google Patents
Pseudopolymorph of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8 4r-(3s-hydroxy-1-methyl)piperidinyl)-4h-1-benzopyran-4-one hydrochlorideInfo
- Publication number
- SI1259507T1 SI1259507T1 SI200130201T SI200130201T SI1259507T1 SI 1259507 T1 SI1259507 T1 SI 1259507T1 SI 200130201 T SI200130201 T SI 200130201T SI 200130201 T SI200130201 T SI 200130201T SI 1259507 T1 SI1259507 T1 SI 1259507T1
- Authority
- SI
- Slovenia
- Prior art keywords
- pseudopolymorph
- benzopyran
- piperidinyl
- chlorophenyl
- dihydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Stereophonic System (AREA)
- Inorganic Insulating Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US48471700A | 2000-01-18 | 2000-01-18 | |
EP01900939A EP1259507B1 (en) | 2000-01-18 | 2001-01-08 | Pseudopolymorph of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8 4r-(3s-hydroxy-1-methyl)piperidinyl]-4h-1-benzopyran-4-one hydrochloride |
PCT/US2001/000519 WO2001053293A1 (en) | 2000-01-18 | 2001-01-08 | Pseudopolymorph of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8[4r-(3s-hydroxy-1-methyl)piperidinyl]-4h-1-benzopyran-4-one |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1259507T1 true SI1259507T1 (en) | 2005-02-28 |
Family
ID=23925305
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200130201T SI1259507T1 (en) | 2000-01-18 | 2001-01-08 | Pseudopolymorph of (-)-cis-2-(2-chlorophenyl)-5,7-dihydroxy-8 4r-(3s-hydroxy-1-methyl)piperidinyl)-4h-1-benzopyran-4-one hydrochloride |
Country Status (26)
Country | Link |
---|---|
EP (1) | EP1259507B1 (da) |
JP (1) | JP2003520797A (da) |
KR (1) | KR100806464B1 (da) |
CN (1) | CN1174977C (da) |
AT (1) | ATE273303T1 (da) |
AU (1) | AU2001226346A1 (da) |
BR (1) | BR0107726A (da) |
CA (1) | CA2397593C (da) |
CZ (1) | CZ301195B6 (da) |
DE (1) | DE60104822T2 (da) |
DK (1) | DK1259507T3 (da) |
EA (1) | EA005247B1 (da) |
ES (1) | ES2222332T3 (da) |
HU (1) | HUP0204126A3 (da) |
IL (2) | IL150638A0 (da) |
MX (1) | MXPA02007005A (da) |
NO (1) | NO322572B1 (da) |
NZ (1) | NZ520280A (da) |
PL (1) | PL200696B1 (da) |
PT (1) | PT1259507E (da) |
SI (1) | SI1259507T1 (da) |
SK (1) | SK287404B6 (da) |
TR (1) | TR200402036T4 (da) |
TW (1) | TWI284129B (da) |
WO (1) | WO2001053293A1 (da) |
ZA (1) | ZA200205639B (da) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2966469T3 (es) | 2016-08-23 | 2024-04-22 | Eisai R&D Man Co Ltd | Terapias combinadas para el tratamiento del carcinoma hepatocelular |
IL269357B1 (en) | 2017-03-16 | 2024-06-01 | Eisai R&D Man Co Ltd | A combination of Era inhibitors and a CDK4/6 inhibitor to be used in a method to treat breast cancer |
EP3903828A4 (en) | 2018-12-21 | 2022-10-05 | Daiichi Sankyo Company, Limited | COMBINATION OF AN ANTIBODY-DRUG CONJUGATE AND A KINASE INHIBITOR |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN164232B (da) * | 1986-04-11 | 1989-02-04 | Hoechst India | |
US5284856A (en) * | 1988-10-28 | 1994-02-08 | Hoechst Aktiengesellschaft | Oncogene-encoded kinases inhibition using 4-H-1-benzopyran-4-one derivatives |
US5908934A (en) * | 1996-09-26 | 1999-06-01 | Bristol-Myers Squibb Company | Process for the preparation of chiral ketone intermediates useful for the preparation of flavopiridol and analogs |
-
2001
- 2001-01-08 CA CA002397593A patent/CA2397593C/en not_active Expired - Lifetime
- 2001-01-08 BR BR0107726-0A patent/BR0107726A/pt not_active Application Discontinuation
- 2001-01-08 ES ES01900939T patent/ES2222332T3/es not_active Expired - Lifetime
- 2001-01-08 EA EA200200775A patent/EA005247B1/ru not_active IP Right Cessation
- 2001-01-08 AU AU2001226346A patent/AU2001226346A1/en not_active Abandoned
- 2001-01-08 DK DK01900939T patent/DK1259507T3/da active
- 2001-01-08 DE DE60104822T patent/DE60104822T2/de not_active Expired - Lifetime
- 2001-01-08 SK SK1036-2002A patent/SK287404B6/sk not_active IP Right Cessation
- 2001-01-08 IL IL15063801A patent/IL150638A0/xx unknown
- 2001-01-08 PT PT01900939T patent/PT1259507E/pt unknown
- 2001-01-08 WO PCT/US2001/000519 patent/WO2001053293A1/en active IP Right Grant
- 2001-01-08 AT AT01900939T patent/ATE273303T1/de active
- 2001-01-08 CN CNB018038476A patent/CN1174977C/zh not_active Expired - Lifetime
- 2001-01-08 SI SI200130201T patent/SI1259507T1/xx unknown
- 2001-01-08 NZ NZ520280A patent/NZ520280A/en not_active IP Right Cessation
- 2001-01-08 CZ CZ20022466A patent/CZ301195B6/cs not_active IP Right Cessation
- 2001-01-08 EP EP01900939A patent/EP1259507B1/en not_active Expired - Lifetime
- 2001-01-08 JP JP2001553767A patent/JP2003520797A/ja active Pending
- 2001-01-08 MX MXPA02007005A patent/MXPA02007005A/es active IP Right Grant
- 2001-01-08 PL PL356165A patent/PL200696B1/pl unknown
- 2001-01-08 TR TR2004/02036T patent/TR200402036T4/xx unknown
- 2001-01-08 HU HU0204126A patent/HUP0204126A3/hu unknown
- 2001-01-08 KR KR1020027009215A patent/KR100806464B1/ko active IP Right Grant
- 2001-01-16 TW TW090100957A patent/TWI284129B/zh not_active IP Right Cessation
-
2002
- 2002-07-08 IL IL150638A patent/IL150638A/en active IP Right Grant
- 2002-07-12 NO NO20023386A patent/NO322572B1/no not_active IP Right Cessation
- 2002-07-15 ZA ZA200205639A patent/ZA200205639B/xx unknown
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