SI1070051T1 - Postopek za proizvodnjo R-(+)-6-karboksamido 3-N-metilamino 1,2,3,4 tetrahidrokarbazola - Google Patents
Postopek za proizvodnjo R-(+)-6-karboksamido 3-N-metilamino 1,2,3,4 tetrahidrokarbazolaInfo
- Publication number
- SI1070051T1 SI1070051T1 SI9931077T SI9931077T SI1070051T1 SI 1070051 T1 SI1070051 T1 SI 1070051T1 SI 9931077 T SI9931077 T SI 9931077T SI 9931077 T SI9931077 T SI 9931077T SI 1070051 T1 SI1070051 T1 SI 1070051T1
- Authority
- SI
- Slovenia
- Prior art keywords
- tetrahydrocarbazole
- carboxamido
- methylamino
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9808069.0A GB9808069D0 (en) | 1998-04-16 | 1998-04-16 | Novel processes |
| EP99915957.7A EP1070051B1 (en) | 1998-04-16 | 1999-04-16 | Process for the production of r-(+)-6- carboxamido- 3-n- methylamino- 1,2,3,4- tetrahydrocarbazole |
| PCT/GB1999/001167 WO1999054302A1 (en) | 1998-04-16 | 1999-04-16 | Process for the production of r-(+)-6- carboxamido- 3-n- methylamino- 1,2,3,4- tetrahydrocarbazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1070051T1 true SI1070051T1 (sl) | 2015-07-31 |
Family
ID=10830430
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9931077T SI1070051T1 (sl) | 1998-04-16 | 1999-04-16 | Postopek za proizvodnjo R-(+)-6-karboksamido 3-N-metilamino 1,2,3,4 tetrahidrokarbazola |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US6359146B1 (cs) |
| EP (1) | EP1070051B1 (cs) |
| JP (1) | JP4756740B2 (cs) |
| KR (1) | KR100612183B1 (cs) |
| CN (1) | CN1200931C (cs) |
| AR (1) | AR015771A1 (cs) |
| AU (1) | AU3437099A (cs) |
| BR (1) | BR9909627A (cs) |
| CA (1) | CA2328345C (cs) |
| CY (1) | CY1116418T1 (cs) |
| CZ (1) | CZ297303B6 (cs) |
| DK (1) | DK1070051T3 (cs) |
| EA (1) | EA004586B1 (cs) |
| EE (1) | EE05156B1 (cs) |
| ES (1) | ES2541432T3 (cs) |
| GB (1) | GB9808069D0 (cs) |
| HR (1) | HRP20000683B1 (cs) |
| HU (1) | HU230559B1 (cs) |
| ID (1) | ID26783A (cs) |
| IL (1) | IL139017A (cs) |
| MX (1) | MXPA00010127A (cs) |
| MY (1) | MY126530A (cs) |
| NO (1) | NO317883B1 (cs) |
| PL (1) | PL210864B1 (cs) |
| PT (1) | PT1070051E (cs) |
| SI (1) | SI1070051T1 (cs) |
| SK (1) | SK286425B6 (cs) |
| TR (1) | TR200100142T2 (cs) |
| TW (1) | TWI255812B (cs) |
| UA (1) | UA70943C2 (cs) |
| WO (1) | WO1999054302A1 (cs) |
| YU (1) | YU62800A (cs) |
| ZA (1) | ZA200006303B (cs) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010073253A1 (en) * | 2008-12-22 | 2010-07-01 | Natco Pharma Limited | Method for preparing an optically active frovatriptan |
| WO2011095803A1 (en) * | 2010-02-02 | 2011-08-11 | Generics [Uk] Limited | Hplc method for analyzing frovatriptan |
| EP2816030A1 (en) | 2013-06-20 | 2014-12-24 | Duke Chem, S. A. | Process for the preparation of frovatriptan and its enantiomer |
| CN103421855B (zh) * | 2013-08-13 | 2016-04-13 | 凯莱英医药集团（天津）股份有限公司 | 一种制备琥珀酸夫罗曲坦关键中间体的方法 |
| CN104529871A (zh) * | 2014-12-22 | 2015-04-22 | 青岛正大海尔制药有限公司 | 一种琥珀酸呋罗曲坦的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2528267A (en) * | 1950-10-31 | Eobeet j | ||
| NL7514300A (nl) * | 1975-12-09 | 1977-06-13 | Stamicarbon | Werkwijze voor de bereiding van optisch actief fenylglycineamide. |
| JPS6259274A (ja) * | 1985-05-29 | 1987-03-14 | Sumitomo Pharmaceut Co Ltd | 光学活性なフエニルセリン誘導体の製造方法 |
| GB9113802D0 (en) * | 1991-06-26 | 1991-08-14 | Smithkline Beecham Plc | Medicaments |
| US5827871A (en) | 1991-06-26 | 1998-10-27 | Smithkline Beecham Plc | Medicaments 1,2,3,4-tetrahydrocarbazoles and 5-HT1 agonist use thereof |
| GB9226530D0 (en) * | 1992-12-21 | 1993-02-17 | Smithkline Beecham Plc | Compounds |
| US5616603A (en) | 1995-05-26 | 1997-04-01 | Smithkline Beecham Plc | Enantiomers of carbazole derivatives as 5-HT1 -like agonists |
| IL110255A (en) * | 1993-07-16 | 1998-12-06 | Merck & Co Inc | Formation and resolution of 2-tert-butylcarboxamido-piperazine |
| JPH07229341A (ja) * | 1994-02-15 | 1995-08-29 | Takero Mori | 観音開き扉用ロック |
| US5618948A (en) | 1995-05-26 | 1997-04-08 | Smithkline Beecham P.L.C. | Process for preparing an enantiomer of a carbazole derivative |
| US5917054A (en) | 1995-07-18 | 1999-06-29 | Smithkline Beecham P.L.C. | Process for preparing enantiomers of carbazole derivatives as 5-HT1 -like agonists |
-
1998
- 1998-04-16 GB GBGB9808069.0A patent/GB9808069D0/en not_active Ceased
-
1999
- 1999-04-16 EE EEP200000597A patent/EE05156B1/xx unknown
- 1999-04-16 CZ CZ20003823A patent/CZ297303B6/cs not_active IP Right Cessation
- 1999-04-16 SK SK1518-2000A patent/SK286425B6/sk not_active IP Right Cessation
- 1999-04-16 ID IDW20002365A patent/ID26783A/id unknown
- 1999-04-16 HR HRP20000683AA patent/HRP20000683B1/hr not_active IP Right Cessation
- 1999-04-16 PT PT99915957T patent/PT1070051E/pt unknown
- 1999-04-16 YU YU62800A patent/YU62800A/sh unknown
- 1999-04-16 SI SI9931077T patent/SI1070051T1/sl unknown
- 1999-04-16 EA EA200001080A patent/EA004586B1/ru not_active IP Right Cessation
- 1999-04-16 DK DK99915957.7T patent/DK1070051T3/en active
- 1999-04-16 WO PCT/GB1999/001167 patent/WO1999054302A1/en not_active Ceased
- 1999-04-16 MX MXPA00010127A patent/MXPA00010127A/es active IP Right Grant
- 1999-04-16 TR TR2001/00142T patent/TR200100142T2/xx unknown
- 1999-04-16 BR BR9909627-7A patent/BR9909627A/pt not_active Application Discontinuation
- 1999-04-16 AR ARP990101781A patent/AR015771A1/es active IP Right Grant
- 1999-04-16 EP EP99915957.7A patent/EP1070051B1/en not_active Expired - Lifetime
- 1999-04-16 ES ES99915957.7T patent/ES2541432T3/es not_active Expired - Lifetime
- 1999-04-16 AU AU34370/99A patent/AU3437099A/en not_active Abandoned
- 1999-04-16 MY MYPI99001476A patent/MY126530A/en unknown
- 1999-04-16 CA CA2328345A patent/CA2328345C/en not_active Expired - Lifetime
- 1999-04-16 IL IL13901799A patent/IL139017A/xx not_active IP Right Cessation
- 1999-04-16 KR KR1020007011362A patent/KR100612183B1/ko not_active Expired - Lifetime
- 1999-04-16 HU HU0101445A patent/HU230559B1/hu unknown
- 1999-04-16 JP JP2000544643A patent/JP4756740B2/ja not_active Expired - Lifetime
- 1999-04-16 CN CNB998072516A patent/CN1200931C/zh not_active Expired - Lifetime
- 1999-04-16 UA UA2000116417A patent/UA70943C2/uk unknown
- 1999-04-16 PL PL343528A patent/PL210864B1/pl unknown
- 1999-05-03 TW TW088107131A patent/TWI255812B/zh active
-
2000
- 2000-10-13 NO NO20005158A patent/NO317883B1/no not_active IP Right Cessation
- 2000-10-13 US US09/689,661 patent/US6359146B1/en not_active Expired - Lifetime
- 2000-11-03 ZA ZA200006303A patent/ZA200006303B/en unknown
-
2015
- 2015-06-23 CY CY20151100532T patent/CY1116418T1/el unknown
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