SI1047678T1 - 1-substituted-1-aminomethyl-cycloalkane derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders - Google Patents

1-substituted-1-aminomethyl-cycloalkane derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders

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Publication number
SI1047678T1
SI1047678T1 SI9830690T SI9830690T SI1047678T1 SI 1047678 T1 SI1047678 T1 SI 1047678T1 SI 9830690 T SI9830690 T SI 9830690T SI 9830690 T SI9830690 T SI 9830690T SI 1047678 T1 SI1047678 T1 SI 1047678T1
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SI
Slovenia
Prior art keywords
integer
treatment
disorders
aminomethyl
substituted
Prior art date
Application number
SI9830690T
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English (en)
Slovenian (sl)
Inventor
Justin Stephen Bryans
Thomas Capiris
David Christopher Horwell
Clare Octavia Kneen
David Juergen Wustrow
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Warner-Lambert Company Llc
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Publication date
Application filed by Warner-Lambert Company Llc filed Critical Warner-Lambert Company Llc
Publication of SI1047678T1 publication Critical patent/SI1047678T1/xx

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    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P25/08Antiepileptics; Anticonvulsants
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    • A61P25/00Drugs for disorders of the nervous system
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    • C07C233/36Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
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    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
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    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
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SI9830690T 1997-12-16 1998-11-10 1-substituted-1-aminomethyl-cycloalkane derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders SI1047678T1 (en)

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Application Number Priority Date Filing Date Title
US6977397P 1997-12-16 1997-12-16
US10500598P 1998-10-20 1998-10-20
PCT/US1998/023918 WO1999031075A1 (en) 1997-12-16 1998-11-10 1-substituted-1-aminomethyl-cycloalkane derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders

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SI1047678T1 true SI1047678T1 (en) 2005-02-28

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EP1047678A1 (en) 2000-11-02
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NO20041112L (no) 2000-06-14
IL135313A0 (en) 2001-05-20
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IS5435A (is) 2000-04-07
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PL341291A1 (en) 2001-04-09
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AU765802B2 (en) 2003-10-02
CA2304974C (en) 2005-10-25
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TR200001795T2 (tr) 2000-11-21
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NO20003039L (no) 2000-06-14
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