SI0971901T1 - Phthalazinones - Google Patents
PhthalazinonesInfo
- Publication number
- SI0971901T1 SI0971901T1 SI9830396T SI9830396T SI0971901T1 SI 0971901 T1 SI0971901 T1 SI 0971901T1 SI 9830396 T SI9830396 T SI 9830396T SI 9830396 T SI9830396 T SI 9830396T SI 0971901 T1 SI0971901 T1 SI 0971901T1
- Authority
- SI
- Slovenia
- Prior art keywords
- pct
- date jul
- sec
- pub
- phthalazinones
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Otolaryngology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Lubricants (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97100488 | 1997-01-15 | ||
EP98901959A EP0971901B1 (en) | 1997-01-15 | 1998-01-12 | Phthalazinones |
PCT/EP1998/000124 WO1998031674A1 (en) | 1997-01-15 | 1998-01-12 | Phthalazinones |
Publications (1)
Publication Number | Publication Date |
---|---|
SI0971901T1 true SI0971901T1 (en) | 2003-10-31 |
Family
ID=8226366
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI9830396T SI0971901T1 (en) | 1997-01-15 | 1998-01-12 | Phthalazinones |
Country Status (27)
Country | Link |
---|---|
US (1) | US6103718A (zh) |
EP (1) | EP0971901B1 (zh) |
JP (1) | JP2001508078A (zh) |
KR (1) | KR20000070150A (zh) |
CN (1) | CN1127487C (zh) |
AT (1) | ATE233247T1 (zh) |
AU (1) | AU735934B2 (zh) |
BR (1) | BR9806752A (zh) |
CA (1) | CA2276455C (zh) |
CY (1) | CY2446B1 (zh) |
CZ (1) | CZ293815B6 (zh) |
DE (1) | DE69811645T2 (zh) |
DK (1) | DK0971901T3 (zh) |
EA (1) | EA002764B1 (zh) |
EE (1) | EE03968B1 (zh) |
ES (1) | ES2193508T3 (zh) |
HK (1) | HK1024692A1 (zh) |
HU (1) | HUP0001541A3 (zh) |
IL (1) | IL130659A (zh) |
NO (1) | NO313137B1 (zh) |
NZ (1) | NZ336573A (zh) |
PL (1) | PL189418B1 (zh) |
PT (1) | PT971901E (zh) |
SI (1) | SI0971901T1 (zh) |
SK (1) | SK283270B6 (zh) |
TR (1) | TR199901653T2 (zh) |
WO (1) | WO1998031674A1 (zh) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1070056B1 (en) * | 1998-03-14 | 2004-06-30 | ALTANA Pharma AG | Phthalazinone pde iii/iv inhibitors |
DE60026855T2 (de) | 1999-08-21 | 2006-12-07 | Altana Pharma Ag | Synergistische kombination von roflumilast und salmeterol |
AU7654200A (en) * | 1999-09-14 | 2001-04-17 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Phthalazinone derivatives as pd3/4 inhibitors |
JP2003512466A (ja) * | 1999-10-25 | 2003-04-02 | アルタナ ファルマ アクチエンゲゼルシャフト | Pde4インヒビターとしてのテトラヒドロチオピランフタラジノン誘導体 |
WO2001030766A1 (en) * | 1999-10-25 | 2001-05-03 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Phthalazinone derivatives as pde 4 inhibitors |
JP2003535850A (ja) | 2000-06-05 | 2003-12-02 | アルタナ ファルマ アクチエンゲゼルシャフト | β−2−アドレナリン受容体として効果的な化合物並びにPDE4−インヒビター |
US20040224316A1 (en) * | 2000-08-10 | 2004-11-11 | Tully Timothy P. | Augmented cognitive training |
US7868015B2 (en) * | 2000-08-10 | 2011-01-11 | Cold Spring Harbor Laboratory | Phosphodiesesterase 4 inhibitors for the treatment of a cognitive deficit |
CZ20032491A3 (cs) | 2001-02-15 | 2004-01-14 | Altana Pharma Ag | Ftalazinonpiperidinové deriváty |
BR0209076A (pt) | 2001-04-25 | 2004-08-10 | Altana Pharma Ag | Derivados de piperazino e seu uso como inibidor de pde4 |
EP1385848A2 (en) * | 2001-04-25 | 2004-02-04 | ALTANA Pharma AG | Phtalazinones derivatives useful as pde4/7 inhibitors |
BR0307780A (pt) | 2002-02-19 | 2004-12-28 | Ono Pharmaceutical Co | Compostos derivados de piridazina fundida e medicamentos contendo os compostos como o ingrediente ativo |
WO2004018449A1 (en) * | 2002-08-10 | 2004-03-04 | Altana Pharma Ag | Piperidine-derivatives as pde4 inhibitors |
US20060166995A1 (en) * | 2002-08-10 | 2006-07-27 | Altana Pharma Ag | Piperidine-n-oxide-derivatives |
MXPA05001354A (es) * | 2002-08-10 | 2005-04-28 | Altana Pharma Ag | Piperidina-ftalazonas sustituidas por pirrolidinodiona como inhibidores pde4. |
WO2004018451A1 (en) * | 2002-08-10 | 2004-03-04 | Altana Pharma Ag | Pyridazinone-derivatives as pde4 inhibitors |
WO2004098633A1 (en) * | 2003-05-12 | 2004-11-18 | Altana Pharma Ag | Composition comprising a pde-4 inhibitor and a tnf alpha antagonist |
US7365215B2 (en) * | 2003-07-14 | 2008-04-29 | Ube Industries, Ltd. | Process for preparing 4-aminotetrahydropyran compound and an acid salt thereof, synthetic intermediate thereof and process for preparing the same |
WO2005075437A1 (en) * | 2004-02-04 | 2005-08-18 | Altana Pharma Ag | Pyridazinone derivatives and their use as pde4 inhibitors |
JP4778449B2 (ja) * | 2004-02-04 | 2011-09-21 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | Pde4インヒビターとしての2−(ピペリジン−4−イル)−4,5−ジヒドロ−2h−ピリダジン−3−オン誘導体 |
CA2605383A1 (en) * | 2005-04-21 | 2006-11-02 | Nippon Shinyaku Co., Ltd. | Phthalazinone derivative and pharmaceutical comprising the same |
JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス,インコーポレイティド | ムスカリン性受容体調節による神経発生 |
EP2258357A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
AU2006304787A1 (en) | 2005-10-21 | 2007-04-26 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
US20070112017A1 (en) | 2005-10-31 | 2007-05-17 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
EP2026813A2 (en) | 2006-05-09 | 2009-02-25 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
EP2021000A2 (en) | 2006-05-09 | 2009-02-11 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
JP2010502722A (ja) | 2006-09-08 | 2010-01-28 | ブレインセルス,インコーポレイティド | 4−アシルアミノピリジン誘導体を含む組み合わせ |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
EP2402330B1 (en) * | 2007-05-16 | 2013-06-26 | Takeda GmbH | Pyrazolone-derivatives as PDE4 inhibitors |
AR074318A1 (es) * | 2008-11-14 | 2011-01-05 | Nycomed Gmbh | Derivados heterociclicos de pirazolona, composiciones farmaceuticas que los contienen y uso de los mismos para el tratamiento de enfermedades de las vias respiratorias. |
US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
CN103582644B (zh) * | 2011-06-17 | 2016-07-20 | 塔科达有限责任公司 | 酞嗪酮-吡咯并嘧啶羧酰胺衍生物 |
EP2804603A1 (en) | 2012-01-10 | 2014-11-26 | President and Fellows of Harvard College | Beta-cell replication promoting compounds and methods of their use |
CN105307655B (zh) | 2013-03-13 | 2019-05-03 | 弗拉特利发现实验室有限责任公司 | 哒嗪酮化合物及其用于制备治疗囊肿状纤维化的药物的应用 |
US20150050626A1 (en) * | 2013-03-15 | 2015-02-19 | Dart Neuroscience, Llc | Systems, Methods, and Software for Improving Cognitive and Motor Abilities |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2845456A1 (de) * | 1978-10-19 | 1980-08-14 | Merck Patent Gmbh | 6-arylpyridazin-3-one und verfahren zu ihrer herstellung |
DE69332762T2 (de) * | 1992-12-02 | 2003-08-14 | Pfizer Inc., New York | Cathecoldiether als selektive pde iv hemmungsmittel |
EP0634404A1 (en) * | 1993-07-13 | 1995-01-18 | Rhone Poulenc Agriculture Ltd. | Phtalazin derivatives and their use as pesticides |
NZ290952A (en) * | 1994-08-09 | 1998-05-27 | Eisai Co Ltd | Phthalazine derivatives optionally substituted in position-1 by (generally benzyl) amino groups |
-
1998
- 1998-01-12 BR BR9806752-4A patent/BR9806752A/pt active Search and Examination
- 1998-01-12 CA CA002276455A patent/CA2276455C/en not_active Expired - Fee Related
- 1998-01-12 CN CN98803169A patent/CN1127487C/zh not_active Expired - Fee Related
- 1998-01-12 PT PT98901959T patent/PT971901E/pt unknown
- 1998-01-12 EE EEP199900274A patent/EE03968B1/xx not_active IP Right Cessation
- 1998-01-12 AT AT98901959T patent/ATE233247T1/de not_active IP Right Cessation
- 1998-01-12 KR KR1019997006376A patent/KR20000070150A/ko not_active Application Discontinuation
- 1998-01-12 AU AU58629/98A patent/AU735934B2/en not_active Ceased
- 1998-01-12 CZ CZ19992533A patent/CZ293815B6/cs not_active IP Right Cessation
- 1998-01-12 SI SI9830396T patent/SI0971901T1/xx unknown
- 1998-01-12 SK SK951-99A patent/SK283270B6/sk unknown
- 1998-01-12 DK DK98901959T patent/DK0971901T3/da active
- 1998-01-12 EP EP98901959A patent/EP0971901B1/en not_active Expired - Lifetime
- 1998-01-12 WO PCT/EP1998/000124 patent/WO1998031674A1/en not_active Application Discontinuation
- 1998-01-12 EA EA199900620A patent/EA002764B1/ru not_active IP Right Cessation
- 1998-01-12 IL IL13065998A patent/IL130659A/en not_active IP Right Cessation
- 1998-01-12 HU HU0001541A patent/HUP0001541A3/hu unknown
- 1998-01-12 ES ES98901959T patent/ES2193508T3/es not_active Expired - Lifetime
- 1998-01-12 US US09/341,135 patent/US6103718A/en not_active Expired - Fee Related
- 1998-01-12 JP JP53363598A patent/JP2001508078A/ja not_active Ceased
- 1998-01-12 TR TR1999/01653T patent/TR199901653T2/xx unknown
- 1998-01-12 DE DE69811645T patent/DE69811645T2/de not_active Expired - Fee Related
- 1998-01-12 NZ NZ336573A patent/NZ336573A/xx unknown
- 1998-01-12 PL PL98334561A patent/PL189418B1/pl not_active IP Right Cessation
-
1999
- 1999-07-02 NO NO19993301A patent/NO313137B1/no unknown
-
2000
- 2000-06-30 HK HK00103993A patent/HK1024692A1/xx not_active IP Right Cessation
-
2004
- 2004-08-11 CY CY0400064A patent/CY2446B1/xx unknown
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