SI0891345T1 - Novel furan diarylmethylidene derivatives, method for their preparation and therapeutical uses thereof - Google Patents
Novel furan diarylmethylidene derivatives, method for their preparation and therapeutical uses thereofInfo
- Publication number
- SI0891345T1 SI0891345T1 SI9730222T SI9730222T SI0891345T1 SI 0891345 T1 SI0891345 T1 SI 0891345T1 SI 9730222 T SI9730222 T SI 9730222T SI 9730222 T SI9730222 T SI 9730222T SI 0891345 T1 SI0891345 T1 SI 0891345T1
- Authority
- SI
- Slovenia
- Prior art keywords
- preparation
- therapeutical uses
- novel furan
- diarylmethylidene
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/58—One oxygen atom, e.g. butenolide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Rheumatology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9604236A FR2747123B1 (fr) | 1996-04-04 | 1996-04-04 | Nouveaux derives diarylmethylidene tetrahydrofurane, leurs procedes de preparation, et leurs utilisations en therapeutique |
| FR9607922A FR2747124B1 (fr) | 1996-04-04 | 1996-06-26 | Nouveaux derives diarylmethylidene furaniques, leurs procedes de preparation et leurs utilisations en therapeutique |
| PCT/FR1997/000602 WO1997037984A1 (fr) | 1996-04-04 | 1997-04-03 | Nouveaux derives diarylmethylidene furaniques, leurs procedes de preparation et leurs utilisations en therapeutique |
| EP97919476A EP0891345B1 (fr) | 1996-04-04 | 1997-04-03 | Nouveaux derives diarylmethylidene furaniques, leurs procedes de preparation et leurs utilisations en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI0891345T1 true SI0891345T1 (en) | 2002-02-28 |
Family
ID=9490907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9730222T SI0891345T1 (en) | 1996-04-04 | 1997-04-03 | Novel furan diarylmethylidene derivatives, method for their preparation and therapeutical uses thereof |
Country Status (28)
| Country | Link |
|---|---|
| EP (1) | EP0891345B1 (es) |
| JP (1) | JP2000508638A (es) |
| KR (1) | KR20000005146A (es) |
| CN (1) | CN1215396A (es) |
| AR (1) | AR006539A1 (es) |
| AT (1) | ATE204268T1 (es) |
| AU (1) | AU717146B2 (es) |
| BG (1) | BG62808B1 (es) |
| BR (1) | BR9708510A (es) |
| CA (1) | CA2248949A1 (es) |
| CZ (1) | CZ318898A3 (es) |
| DE (1) | DE69706157T2 (es) |
| DK (1) | DK0891345T3 (es) |
| EE (1) | EE03687B1 (es) |
| ES (1) | ES2162678T3 (es) |
| FR (2) | FR2747123B1 (es) |
| GE (1) | GEP20032924B (es) |
| IL (1) | IL126105A (es) |
| NO (1) | NO984624L (es) |
| NZ (1) | NZ331672A (es) |
| PL (1) | PL329213A1 (es) |
| PT (1) | PT891345E (es) |
| RU (1) | RU2189979C2 (es) |
| SI (1) | SI0891345T1 (es) |
| SK (1) | SK283292B6 (es) |
| TW (1) | TW353660B (es) |
| WO (1) | WO1997037984A1 (es) |
| ZA (1) | ZA972894B (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6180651B1 (en) * | 1996-04-04 | 2001-01-30 | Bristol-Myers Squibb | Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics |
| JP2001518087A (ja) * | 1997-04-02 | 2001-10-09 | メルク フロスト カナダ アンド カンパニー | 選択的シクロオキシゲナーゼ−２阻害薬としてのα−メチレン−γ−ラクトン類 |
| FR2775477B1 (fr) * | 1998-02-27 | 2000-05-19 | Union Pharma Scient Appl | Nouveaux derives diarylmethylene heterocycliques, leurs procedes de preparation et leurs utilisations en therapeutique |
| CN1106392C (zh) * | 2000-10-24 | 2003-04-23 | 中国科学院上海有机化学研究所 | 一种β位不含取代基的丁烯酸内酯及其合成的方法 |
| EP1562930A4 (en) * | 2002-11-05 | 2008-12-10 | Magnachem Int Lab Inc | SYNTHETIC LACTONE FORMULATIONS AND METHOD OF USE |
| ATE515493T1 (de) * | 2003-03-31 | 2011-07-15 | Council Scient Ind Res | Mercaptophenylnaphthylmethan-derivate und deren herstellung |
| PL1745791T3 (pl) | 2003-05-07 | 2013-11-29 | Osteologix As | Leczenie chorób chrząstki/kości za pomocą rozpuszczalnych w wodzie soli strontu |
| US8779168B2 (en) * | 2010-12-16 | 2014-07-15 | Transitions Optical, Inc. | Lactone compounds and materials made therefrom |
| CA3209491A1 (en) | 2021-03-15 | 2022-09-22 | Saul Yedgar | Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory disease |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0759432A1 (en) * | 1993-01-15 | 1997-02-26 | G.D. Searle & Co. | Use of medicaments containing 3,4-diaryl furans and analogs thereof for treating a skin-related condition |
| US5474995A (en) * | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
| US5585504A (en) * | 1994-09-16 | 1996-12-17 | Merck & Co., Inc. | Process of making cox-2 inhibitors having a lactone bridge |
-
1996
- 1996-04-04 FR FR9604236A patent/FR2747123B1/fr not_active Expired - Fee Related
- 1996-06-26 FR FR9607922A patent/FR2747124B1/fr not_active Expired - Lifetime
-
1997
- 1997-03-24 TW TW086103701A patent/TW353660B/zh active
- 1997-04-03 EE EE9800333A patent/EE03687B1/xx unknown
- 1997-04-03 CA CA002248949A patent/CA2248949A1/fr not_active Abandoned
- 1997-04-03 IL IL12610597A patent/IL126105A/xx not_active IP Right Cessation
- 1997-04-03 RU RU98119887/04A patent/RU2189979C2/ru not_active IP Right Cessation
- 1997-04-03 AU AU23933/97A patent/AU717146B2/en not_active Ceased
- 1997-04-03 CZ CZ983188A patent/CZ318898A3/cs unknown
- 1997-04-03 BR BR9708510A patent/BR9708510A/pt not_active IP Right Cessation
- 1997-04-03 JP JP9535910A patent/JP2000508638A/ja active Pending
- 1997-04-03 DE DE69706157T patent/DE69706157T2/de not_active Expired - Lifetime
- 1997-04-03 WO PCT/FR1997/000602 patent/WO1997037984A1/fr not_active Application Discontinuation
- 1997-04-03 ES ES97919476T patent/ES2162678T3/es not_active Expired - Lifetime
- 1997-04-03 EP EP97919476A patent/EP0891345B1/fr not_active Expired - Lifetime
- 1997-04-03 CN CN97193543A patent/CN1215396A/zh active Pending
- 1997-04-03 SK SK1375-98A patent/SK283292B6/sk not_active IP Right Cessation
- 1997-04-03 PT PT97919476T patent/PT891345E/pt unknown
- 1997-04-03 SI SI9730222T patent/SI0891345T1/xx unknown
- 1997-04-03 DK DK97919476T patent/DK0891345T3/da active
- 1997-04-03 NZ NZ331672A patent/NZ331672A/en unknown
- 1997-04-03 GE GEAP19974555A patent/GEP20032924B/en unknown
- 1997-04-03 AT AT97919476T patent/ATE204268T1/de active
- 1997-04-03 KR KR1019980707808A patent/KR20000005146A/ko not_active Application Discontinuation
- 1997-04-03 PL PL97329213A patent/PL329213A1/xx unknown
- 1997-04-04 ZA ZA9702894A patent/ZA972894B/xx unknown
- 1997-04-04 AR ARP970101359A patent/AR006539A1/es not_active Application Discontinuation
-
1998
- 1998-09-16 BG BG102771A patent/BG62808B1/bg unknown
- 1998-10-02 NO NO984624A patent/NO984624L/no not_active Application Discontinuation
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