SI0891345T1 - Novi diarilmetiliden furanski derivati, postopki za njihovo pripravo in njihove terapevtske uporabe - Google Patents

Novi diarilmetiliden furanski derivati, postopki za njihovo pripravo in njihove terapevtske uporabe

Info

Publication number
SI0891345T1
SI0891345T1 SI9730222T SI9730222T SI0891345T1 SI 0891345 T1 SI0891345 T1 SI 0891345T1 SI 9730222 T SI9730222 T SI 9730222T SI 9730222 T SI9730222 T SI 9730222T SI 0891345 T1 SI0891345 T1 SI 0891345T1
Authority
SI
Slovenia
Prior art keywords
preparation
therapeutical uses
novel furan
diarylmethylidene
derivatives
Prior art date
Application number
SI9730222T
Other languages
English (en)
Inventor
Eric Nicolai
Jean-Marie Teulon
Original Assignee
Laboratoires Upsa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Upsa filed Critical Laboratoires Upsa
Publication of SI0891345T1 publication Critical patent/SI0891345T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06Antiabortive agents; Labour repressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/58One oxygen atom, e.g. butenolide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Gynecology & Obstetrics (AREA)
  • Psychiatry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
SI9730222T 1996-04-04 1997-04-03 Novi diarilmetiliden furanski derivati, postopki za njihovo pripravo in njihove terapevtske uporabe SI0891345T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9604236A FR2747123B1 (fr) 1996-04-04 1996-04-04 Nouveaux derives diarylmethylidene tetrahydrofurane, leurs procedes de preparation, et leurs utilisations en therapeutique
FR9607922A FR2747124B1 (fr) 1996-04-04 1996-06-26 Nouveaux derives diarylmethylidene furaniques, leurs procedes de preparation et leurs utilisations en therapeutique
EP97919476A EP0891345B1 (fr) 1996-04-04 1997-04-03 Nouveaux derives diarylmethylidene furaniques, leurs procedes de preparation et leurs utilisations en therapeutique
PCT/FR1997/000602 WO1997037984A1 (fr) 1996-04-04 1997-04-03 Nouveaux derives diarylmethylidene furaniques, leurs procedes de preparation et leurs utilisations en therapeutique

Publications (1)

Publication Number Publication Date
SI0891345T1 true SI0891345T1 (sl) 2002-02-28

Family

ID=9490907

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9730222T SI0891345T1 (sl) 1996-04-04 1997-04-03 Novi diarilmetiliden furanski derivati, postopki za njihovo pripravo in njihove terapevtske uporabe

Country Status (28)

Country Link
EP (1) EP0891345B1 (sl)
JP (1) JP2000508638A (sl)
KR (1) KR20000005146A (sl)
CN (1) CN1215396A (sl)
AR (1) AR006539A1 (sl)
AT (1) ATE204268T1 (sl)
AU (1) AU717146B2 (sl)
BG (1) BG62808B1 (sl)
BR (1) BR9708510A (sl)
CA (1) CA2248949A1 (sl)
CZ (1) CZ318898A3 (sl)
DE (1) DE69706157T2 (sl)
DK (1) DK0891345T3 (sl)
EE (1) EE03687B1 (sl)
ES (1) ES2162678T3 (sl)
FR (2) FR2747123B1 (sl)
GE (1) GEP20032924B (sl)
IL (1) IL126105A (sl)
NO (1) NO984624L (sl)
NZ (1) NZ331672A (sl)
PL (1) PL329213A1 (sl)
PT (1) PT891345E (sl)
RU (1) RU2189979C2 (sl)
SI (1) SI0891345T1 (sl)
SK (1) SK283292B6 (sl)
TW (1) TW353660B (sl)
WO (1) WO1997037984A1 (sl)
ZA (1) ZA972894B (sl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6180651B1 (en) * 1996-04-04 2001-01-30 Bristol-Myers Squibb Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics
EP0971910A1 (en) * 1997-04-02 2000-01-19 Merck Frosst Canada & Co. Alpha-methylene gamma lactones as selective cyclooxygenase-2 inhibitors
FR2775477B1 (fr) * 1998-02-27 2000-05-19 Union Pharma Scient Appl Nouveaux derives diarylmethylene heterocycliques, leurs procedes de preparation et leurs utilisations en therapeutique
CN1106392C (zh) * 2000-10-24 2003-04-23 中国科学院上海有机化学研究所 一种β位不含取代基的丁烯酸内酯及其合成的方法
US7323495B2 (en) * 2002-11-05 2008-01-29 Magnachem International Laboratories, Inc. Synthetic lactone formulations and method of use
ATE515493T1 (de) * 2003-03-31 2011-07-15 Council Scient Ind Res Mercaptophenylnaphthylmethan-derivate und deren herstellung
CA2519189C (en) 2003-05-07 2012-07-17 Osteologix A/S Water-soluble strontium salts for use in treatment of cartilage and/or bone conditions
US8779168B2 (en) * 2010-12-16 2014-07-15 Transitions Optical, Inc. Lactone compounds and materials made therefrom
IL305573A (en) 2021-03-15 2023-10-01 Saul Yedgar Hyaluronic acid conjugated with dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment or suppression of inflammatory diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2111288T3 (es) * 1993-01-15 1998-03-01 Searle & Co Nuevos 3,4-diaril tiofenos y analogos de los mismos utiles como agentes antiinflamatorios.
US5474995A (en) * 1993-06-24 1995-12-12 Merck Frosst Canada, Inc. Phenyl heterocycles as cox-2 inhibitors
US5585504A (en) * 1994-09-16 1996-12-17 Merck & Co., Inc. Process of making cox-2 inhibitors having a lactone bridge

Also Published As

Publication number Publication date
BR9708510A (pt) 1999-08-03
SK283292B6 (sk) 2003-05-02
ES2162678T3 (es) 2002-01-01
AU717146B2 (en) 2000-03-16
CA2248949A1 (fr) 1997-10-16
FR2747123B1 (fr) 1998-06-26
FR2747124A1 (fr) 1997-10-10
IL126105A0 (en) 1999-05-09
EE03687B1 (et) 2002-04-15
RU2189979C2 (ru) 2002-09-27
WO1997037984A1 (fr) 1997-10-16
TW353660B (en) 1999-03-01
BG102771A (en) 1999-06-30
AR006539A1 (es) 1999-09-08
AU2393397A (en) 1997-10-29
BG62808B1 (bg) 2000-08-31
CZ318898A3 (cs) 1999-01-13
PT891345E (pt) 2002-02-28
EP0891345B1 (fr) 2001-08-16
DE69706157T2 (de) 2002-04-11
ATE204268T1 (de) 2001-09-15
GEP20032924B (en) 2003-03-25
NZ331672A (en) 2000-02-28
DE69706157D1 (de) 2001-09-20
ZA972894B (en) 1997-11-04
CN1215396A (zh) 1999-04-28
PL329213A1 (en) 1999-03-15
KR20000005146A (ko) 2000-01-25
EE9800333A (et) 1999-04-15
FR2747123A1 (fr) 1997-10-10
IL126105A (en) 2001-08-26
DK0891345T3 (da) 2001-12-03
NO984624L (no) 1998-11-30
EP0891345A1 (fr) 1999-01-20
SK137598A3 (en) 1999-02-11
NO984624D0 (no) 1998-10-02
FR2747124B1 (fr) 1998-06-26
JP2000508638A (ja) 2000-07-11

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