NO984624L - Nye furan-diarylmetyliden-derivater, fremgangsmÕte for deres fremstilling og terapeutiske anvendelser derav - Google Patents

Nye furan-diarylmetyliden-derivater, fremgangsmÕte for deres fremstilling og terapeutiske anvendelser derav

Info

Publication number
NO984624L
NO984624L NO984624A NO984624A NO984624L NO 984624 L NO984624 L NO 984624L NO 984624 A NO984624 A NO 984624A NO 984624 A NO984624 A NO 984624A NO 984624 L NO984624 L NO 984624L
Authority
NO
Norway
Prior art keywords
preparation
methods
therapeutic uses
diarylmethylidene
derivatives
Prior art date
Application number
NO984624A
Other languages
English (en)
Norwegian (no)
Other versions
NO984624D0 (no
Inventor
Eric Nicolai
Jean-Marie Teulon
Original Assignee
Union Pharma Scient Appl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Union Pharma Scient Appl filed Critical Union Pharma Scient Appl
Publication of NO984624D0 publication Critical patent/NO984624D0/no
Publication of NO984624L publication Critical patent/NO984624L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06Antiabortive agents; Labour repressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/58One oxygen atom, e.g. butenolide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO984624A 1996-04-04 1998-10-02 Nye furan-diarylmetyliden-derivater, fremgangsmÕte for deres fremstilling og terapeutiske anvendelser derav NO984624L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9604236A FR2747123B1 (fr) 1996-04-04 1996-04-04 Nouveaux derives diarylmethylidene tetrahydrofurane, leurs procedes de preparation, et leurs utilisations en therapeutique
FR9607922A FR2747124B1 (fr) 1996-04-04 1996-06-26 Nouveaux derives diarylmethylidene furaniques, leurs procedes de preparation et leurs utilisations en therapeutique
PCT/FR1997/000602 WO1997037984A1 (fr) 1996-04-04 1997-04-03 Nouveaux derives diarylmethylidene furaniques, leurs procedes de preparation et leurs utilisations en therapeutique

Publications (2)

Publication Number Publication Date
NO984624D0 NO984624D0 (no) 1998-10-02
NO984624L true NO984624L (no) 1998-11-30

Family

ID=9490907

Family Applications (1)

Application Number Title Priority Date Filing Date
NO984624A NO984624L (no) 1996-04-04 1998-10-02 Nye furan-diarylmetyliden-derivater, fremgangsmÕte for deres fremstilling og terapeutiske anvendelser derav

Country Status (28)

Country Link
EP (1) EP0891345B1 (es)
JP (1) JP2000508638A (es)
KR (1) KR20000005146A (es)
CN (1) CN1215396A (es)
AR (1) AR006539A1 (es)
AT (1) ATE204268T1 (es)
AU (1) AU717146B2 (es)
BG (1) BG62808B1 (es)
BR (1) BR9708510A (es)
CA (1) CA2248949A1 (es)
CZ (1) CZ318898A3 (es)
DE (1) DE69706157T2 (es)
DK (1) DK0891345T3 (es)
EE (1) EE03687B1 (es)
ES (1) ES2162678T3 (es)
FR (2) FR2747123B1 (es)
GE (1) GEP20032924B (es)
IL (1) IL126105A (es)
NO (1) NO984624L (es)
NZ (1) NZ331672A (es)
PL (1) PL329213A1 (es)
PT (1) PT891345E (es)
RU (1) RU2189979C2 (es)
SI (1) SI0891345T1 (es)
SK (1) SK283292B6 (es)
TW (1) TW353660B (es)
WO (1) WO1997037984A1 (es)
ZA (1) ZA972894B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6180651B1 (en) * 1996-04-04 2001-01-30 Bristol-Myers Squibb Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics
CA2285567A1 (en) * 1997-04-02 1998-10-08 Merck Frosst Canada & Co. Alpha-methylene gamma lactones as selective cyclooxygenase-2 inhibitors
FR2775477B1 (fr) * 1998-02-27 2000-05-19 Union Pharma Scient Appl Nouveaux derives diarylmethylene heterocycliques, leurs procedes de preparation et leurs utilisations en therapeutique
CN1106392C (zh) * 2000-10-24 2003-04-23 中国科学院上海有机化学研究所 一种β位不含取代基的丁烯酸内酯及其合成的方法
US7323495B2 (en) * 2002-11-05 2008-01-29 Magnachem International Laboratories, Inc. Synthetic lactone formulations and method of use
CN100569747C (zh) * 2003-03-31 2009-12-16 科学与工业研究会 巯基-苯基-萘基-甲烷衍生物及其制备
ATE342722T1 (de) 2003-05-07 2006-11-15 Osteologix As Behandlung von knorpel/knochen-erkrankungen mit wasserlöslichen strontiumsalzen
US8779168B2 (en) * 2010-12-16 2014-07-15 Transitions Optical, Inc. Lactone compounds and materials made therefrom
WO2022195579A1 (en) 2021-03-15 2022-09-22 Saul Yedgar Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6027694A (en) * 1993-01-15 1994-08-15 G.D. Searle & Co. Novel 3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents
US5474995A (en) * 1993-06-24 1995-12-12 Merck Frosst Canada, Inc. Phenyl heterocycles as cox-2 inhibitors
US5585504A (en) * 1994-09-16 1996-12-17 Merck & Co., Inc. Process of making cox-2 inhibitors having a lactone bridge

Also Published As

Publication number Publication date
SI0891345T1 (en) 2002-02-28
DE69706157D1 (de) 2001-09-20
CA2248949A1 (fr) 1997-10-16
BG102771A (en) 1999-06-30
ES2162678T3 (es) 2002-01-01
PL329213A1 (en) 1999-03-15
JP2000508638A (ja) 2000-07-11
FR2747123B1 (fr) 1998-06-26
EP0891345B1 (fr) 2001-08-16
SK283292B6 (sk) 2003-05-02
DE69706157T2 (de) 2002-04-11
BR9708510A (pt) 1999-08-03
PT891345E (pt) 2002-02-28
BG62808B1 (bg) 2000-08-31
SK137598A3 (en) 1999-02-11
ATE204268T1 (de) 2001-09-15
EP0891345A1 (fr) 1999-01-20
RU2189979C2 (ru) 2002-09-27
IL126105A (en) 2001-08-26
CN1215396A (zh) 1999-04-28
GEP20032924B (en) 2003-03-25
AU717146B2 (en) 2000-03-16
FR2747124A1 (fr) 1997-10-10
CZ318898A3 (cs) 1999-01-13
TW353660B (en) 1999-03-01
FR2747124B1 (fr) 1998-06-26
EE9800333A (et) 1999-04-15
FR2747123A1 (fr) 1997-10-10
IL126105A0 (en) 1999-05-09
NO984624D0 (no) 1998-10-02
ZA972894B (en) 1997-11-04
AR006539A1 (es) 1999-09-08
EE03687B1 (et) 2002-04-15
NZ331672A (en) 2000-02-28
AU2393397A (en) 1997-10-29
WO1997037984A1 (fr) 1997-10-16
DK0891345T3 (da) 2001-12-03
KR20000005146A (ko) 2000-01-25

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