SI0875252T1 - Activated protein C formulations - Google Patents

Activated protein C formulations

Info

Publication number
SI0875252T1
SI0875252T1 SI9830752T SI9830752T SI0875252T1 SI 0875252 T1 SI0875252 T1 SI 0875252T1 SI 9830752 T SI9830752 T SI 9830752T SI 9830752 T SI9830752 T SI 9830752T SI 0875252 T1 SI0875252 T1 SI 0875252T1
Authority
SI
Slovenia
Prior art keywords
formulations
activated protein
protein
activated
Prior art date
Application number
SI9830752T
Other languages
English (en)
Slovenian (sl)
Inventor
Andrew David Carlson
Theodore Arsay Sheliga
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of SI0875252T1 publication Critical patent/SI0875252T1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4866—Protein C (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6464—Protein C (3.4.21.69)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SI9830752T 1997-04-28 1998-04-28 Activated protein C formulations SI0875252T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4525597P 1997-04-28 1997-04-28
PCT/US1998/008384 WO1998048822A1 (fr) 1997-04-28 1998-04-24 Perfectionnement du traitement de la proteine c activee

Publications (1)

Publication Number Publication Date
SI0875252T1 true SI0875252T1 (en) 2005-06-30

Family

ID=21936854

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9830752T SI0875252T1 (en) 1997-04-28 1998-04-28 Activated protein C formulations

Country Status (35)

Country Link
US (4) US6162629A (fr)
EP (2) EP0875252B1 (fr)
JP (2) JP4383546B2 (fr)
KR (2) KR100450856B1 (fr)
CN (2) CN1227025C (fr)
AR (2) AR015598A1 (fr)
AT (1) ATE285788T1 (fr)
AU (2) AU740753C (fr)
BR (2) BR9809304B1 (fr)
CA (2) CA2288143C (fr)
CO (2) CO4940438A1 (fr)
CZ (1) CZ298429B6 (fr)
DE (1) DE69828330T2 (fr)
DK (1) DK0875252T3 (fr)
EA (2) EA004881B1 (fr)
EG (1) EG23685A (fr)
ES (1) ES2234072T3 (fr)
HK (1) HK1016472A1 (fr)
HU (2) HUP0003401A3 (fr)
ID (2) ID22933A (fr)
IL (2) IL132502A0 (fr)
IN (2) IN187157B (fr)
MY (2) MY120984A (fr)
NO (2) NO995134L (fr)
NZ (2) NZ337828A (fr)
PE (2) PE84799A1 (fr)
PL (2) PL195090B1 (fr)
PT (1) PT875252E (fr)
SI (1) SI0875252T1 (fr)
SV (2) SV1998000051A (fr)
TR (2) TR199902529T2 (fr)
TW (2) TWI242443B (fr)
UA (2) UA55448C2 (fr)
WO (2) WO1998048818A1 (fr)
ZA (2) ZA983497B (fr)

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Also Published As

Publication number Publication date
HU224826B1 (en) 2006-02-28
NO995198D0 (no) 1999-10-25
EP0875252B1 (fr) 2004-12-29
IL132502A0 (en) 2001-03-19
JP4383547B2 (ja) 2009-12-16
UA55448C2 (uk) 2003-04-15
AR015598A1 (es) 2001-05-16
TR199902631T2 (xx) 2000-01-21
ID23172A (id) 2000-03-23
CA2287267C (fr) 2006-08-15
CA2288143C (fr) 2012-08-21
NO995134L (no) 1999-12-21
HUP0100284A2 (hu) 2001-06-28
AU740753C (en) 2002-10-10
HUP0003401A3 (en) 2003-01-28
MY118591A (en) 2004-12-31
TR199902529T2 (xx) 2000-02-21
JP4383546B2 (ja) 2009-12-16
CZ298429B6 (cs) 2007-10-03
EA002149B1 (ru) 2001-12-24
ZA983496B (en) 1999-10-25
CN1235638C (zh) 2006-01-11
HK1016472A1 (en) 1999-11-05
AU7258998A (en) 1998-11-24
PE84799A1 (es) 1999-09-16
EG23685A (en) 2007-05-09
AU7161898A (en) 1998-11-24
EP0875563A3 (fr) 2000-08-02
ID22933A (id) 1999-12-16
WO1998048822A1 (fr) 1998-11-05
NO995198L (no) 1999-10-25
EA199900979A1 (ru) 2000-06-26
JP2001524111A (ja) 2001-11-27
IN187157B (fr) 2002-02-16
NZ500346A (en) 2001-08-31
CZ381099A3 (cs) 2000-03-15
UA73071C2 (en) 2005-06-15
AR012010A1 (es) 2000-09-13
CN1254284A (zh) 2000-05-24
BR9809292A (pt) 2000-07-04
EA199900980A1 (ru) 2000-04-24
WO1998048818A1 (fr) 1998-11-05
NO995134D0 (no) 1999-10-21
EP0875563A2 (fr) 1998-11-04
ES2234072T3 (es) 2005-06-16
CO4940438A1 (es) 2000-07-24
KR20010020325A (ko) 2001-03-15
IL132325A (en) 2005-07-25
JP2001527543A (ja) 2001-12-25
TW585871B (en) 2004-05-01
MY120984A (en) 2005-12-30
KR100450856B1 (ko) 2004-10-02
KR100564189B1 (ko) 2006-03-27
EP0875252A2 (fr) 1998-11-04
CA2287267A1 (fr) 1998-11-05
ATE285788T1 (de) 2005-01-15
US6159468A (en) 2000-12-12
CN1261280A (zh) 2000-07-26
CN1227025C (zh) 2005-11-16
DE69828330D1 (de) 2005-02-03
PL336889A1 (en) 2000-07-17
HUP0100284A3 (en) 2003-08-28
TWI242443B (en) 2005-11-01
CA2288143A1 (fr) 1998-11-05
HUP0003401A2 (hu) 2001-02-28
US6162629A (en) 2000-12-19
BR9809304B1 (pt) 2011-02-08
AU743531B2 (en) 2002-01-31
BR9809304A (pt) 2000-10-17
US6436397B1 (en) 2002-08-20
EA004881B1 (ru) 2004-08-26
PL195642B1 (pl) 2007-10-31
CO4950523A1 (es) 2000-09-01
EP0875252A3 (fr) 2000-07-26
PE86299A1 (es) 1999-09-17
ZA983497B (en) 1999-10-25
IL132325A0 (en) 2001-03-19
DE69828330T2 (de) 2005-10-13
SV1998000050A (es) 1999-01-13
AU740753B2 (en) 2001-11-15
NZ337828A (en) 2001-06-29
KR20010020242A (ko) 2001-03-15
PT875252E (pt) 2005-03-31
IN183798B (fr) 2000-04-15
PL336420A1 (en) 2000-06-19
US6395270B1 (en) 2002-05-28
SV1998000051A (es) 1998-12-11
DK0875252T3 (da) 2005-04-25
PL195090B1 (pl) 2007-08-31

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