IN183798B - - Google Patents
Info
- Publication number
- IN183798B IN183798B IN751CA1998A IN183798B IN 183798 B IN183798 B IN 183798B IN 751CA1998 A IN751CA1998 A IN 751CA1998A IN 183798 B IN183798 B IN 183798B
- Authority
- IN
- India
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4866—Protein C (3.4.21.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6464—Protein C (3.4.21.69)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Vascular Medicine (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4525597P | 1997-04-28 | 1997-04-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
IN183798B true IN183798B (fr) | 2000-04-15 |
Family
ID=21936854
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN751CA1998 IN183798B (fr) | 1997-04-28 | 1998-04-27 | |
IN752CA1998 IN187157B (fr) | 1997-04-28 | 1998-04-27 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN752CA1998 IN187157B (fr) | 1997-04-28 | 1998-04-27 |
Country Status (35)
Country | Link |
---|---|
US (4) | US6159468A (fr) |
EP (2) | EP0875252B1 (fr) |
JP (2) | JP4383546B2 (fr) |
KR (2) | KR100450856B1 (fr) |
CN (2) | CN1227025C (fr) |
AR (2) | AR012010A1 (fr) |
AT (1) | ATE285788T1 (fr) |
AU (2) | AU740753C (fr) |
BR (2) | BR9809304B1 (fr) |
CA (2) | CA2288143C (fr) |
CO (2) | CO4950523A1 (fr) |
CZ (1) | CZ298429B6 (fr) |
DE (1) | DE69828330T2 (fr) |
DK (1) | DK0875252T3 (fr) |
EA (2) | EA002149B1 (fr) |
EG (1) | EG23685A (fr) |
ES (1) | ES2234072T3 (fr) |
HK (1) | HK1016472A1 (fr) |
HU (2) | HUP0003401A3 (fr) |
ID (2) | ID23172A (fr) |
IL (2) | IL132325A (fr) |
IN (2) | IN183798B (fr) |
MY (2) | MY118591A (fr) |
NO (2) | NO995134L (fr) |
NZ (2) | NZ337828A (fr) |
PE (2) | PE86299A1 (fr) |
PL (2) | PL195642B1 (fr) |
PT (1) | PT875252E (fr) |
SI (1) | SI0875252T1 (fr) |
SV (2) | SV1998000050A (fr) |
TR (2) | TR199902631T2 (fr) |
TW (2) | TWI242443B (fr) |
UA (2) | UA55448C2 (fr) |
WO (2) | WO1998048822A1 (fr) |
ZA (2) | ZA983496B (fr) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6630137B1 (en) * | 1997-04-28 | 2003-10-07 | Eli Lilly And Company | Activated protein C formulations |
EA002149B1 (ru) * | 1997-04-28 | 2001-12-24 | Эли Лилли Энд Компани | Улучшенные способы приготовления активированного белка с |
HUP0001237A3 (en) * | 1997-10-20 | 2002-01-28 | Lilly Co Eli | Methods for treating vascular disorders |
US6815533B1 (en) | 1998-07-31 | 2004-11-09 | Eli Lilly And Company | Cryogranulation of activated protein C |
EP1128842B1 (fr) * | 1998-11-13 | 2006-03-15 | Eli Lilly And Company | Utilisation de la proteine c pour la preparation d'un medicament pour le traitement de la thrombopenie immunitaire de l'heparine |
DE69906568T2 (de) * | 1998-11-20 | 2004-02-12 | Eli Lilly And Co., Indianapolis | Behandlung von hämorrhagischem virusfieber mit protein c |
DK1133314T3 (da) * | 1998-11-23 | 2003-04-14 | Lilly Co Eli | Protein C til behandling af seglcellesygdom og thalassæmi |
WO2000033867A1 (fr) * | 1998-12-10 | 2000-06-15 | Eli Lilly And Company | Methode de traitement du purpura thrombopenique et du syndrome hemolytique et uremique |
US6758938B1 (en) * | 1999-08-31 | 2004-07-06 | Micron Technology, Inc. | Delivery of dissolved ozone |
US7204981B2 (en) * | 2000-03-28 | 2007-04-17 | Eli Lilly And Company | Methods of treating diseases with activated protein C |
AU2001262939A1 (en) * | 2000-05-24 | 2001-12-03 | Eli Lilly And Company | Formulations and use of activated protein c and protein c zymogen for treating hypercoagulable states |
ES2309167T3 (es) | 2001-02-19 | 2008-12-16 | Merck Patent Gmbh | Metodo para identificar epitotes de celulas t y metodo para preparar moleculas con inmunogenicidad reducida. |
US7101982B2 (en) * | 2001-03-30 | 2006-09-05 | Immunex Corporation | Control of ph transitions during chromatography |
JP2004535461A (ja) * | 2001-07-19 | 2004-11-25 | ディーエムアイ バイオサイエンシズ インコーポレイテッド | プロテインcの不活性化を抑制するための銅キレート剤の使用 |
CA2462396A1 (fr) | 2001-09-19 | 2003-03-27 | Oklahoma Medical Research Foundation | Traitement de la sepsie avec tafi |
US20030073636A1 (en) * | 2001-09-19 | 2003-04-17 | Oklahoma Medical Research Foundation | Method of treating diabetes |
DE10149030A1 (de) * | 2001-10-05 | 2003-04-10 | Viscum Ag | Stabile galenische gefriergetrocknete Arzneimittelzubereitung von rViscumin |
KR20040040489A (ko) | 2001-10-15 | 2004-05-12 | 카이론 코포레이션 | 조직 인자 경로 억제제(tfpi)의 저용량 투여에 의한패혈증의 치료 |
ATE428439T1 (de) | 2001-12-21 | 2009-05-15 | Novo Nordisk Healthcare Ag | Flüssige zusammensetzung aus faktor vii polypeptiden |
EP1485121A4 (fr) * | 2002-03-08 | 2007-11-07 | Lilly Co Eli | Formulations de proteines c activees |
PL207018B1 (pl) | 2002-06-21 | 2010-10-29 | Novo Nordisk Helth Care Ag | Kompozycja farmaceutyczna, sposób przygotowania stabilnego polipeptydu czynnika VII i zastosowanie polipeptydu czynnika VII |
AU2003285075B2 (en) * | 2002-10-29 | 2009-10-29 | Durect Corporation | Stabilized, solid-state polypeptide particles |
US20070142272A1 (en) * | 2003-01-24 | 2007-06-21 | Zlokovic Berislav V | Neuroprotective activity of activated protein c independent of its anticoagulant activity |
US7897734B2 (en) | 2003-03-26 | 2011-03-01 | Novo Nordisk Healthcare Ag | Method for the production of proteins |
ES2382157T3 (es) * | 2003-06-25 | 2012-06-05 | Novo Nordisk Health Care Ag | Composición líquida de polipépttidos del factor VII |
SG150552A1 (en) * | 2004-03-17 | 2009-03-30 | Chiron Corp | Treatment of severe community-acquired pneumonia by administration of tissue factor pathway inhibitor (tfpi) |
WO2006014839A2 (fr) * | 2004-07-23 | 2006-02-09 | The University Of Rochester | La proteine c activee inhibe les effets secondaires de l'activateur de plasminogene dans le cerveau |
WO2006136033A1 (fr) * | 2005-06-23 | 2006-12-28 | The University Of British Columbia | Polymorphismes de facteur de coagulation iii associes a une prediction relative aux resultats et a la reponse d'un sujet a une therapie |
ES2386972T3 (es) * | 2006-05-31 | 2012-09-10 | Genzyme Corporation | Uso de polisacáridos para la estimulación de la actividad enzimática |
EP2041338A4 (fr) * | 2006-06-09 | 2009-09-30 | Univ British Columbia | Polymorphismes de l'interféron gamma utilisés comme indicateurs de résultat chez des sujets gravement malades |
EP2117514B1 (fr) * | 2007-03-05 | 2011-06-15 | Cadila Healthcare Limited | Compositions comprenant des conjugués de peg-interféron alpha et de la raffinose en tant que cryoprotecteur |
EP2527364A1 (fr) | 2007-03-29 | 2012-11-28 | Abbott Laboratories | Anticorps IL-12 anti-humains cristallins |
US8883146B2 (en) | 2007-11-30 | 2014-11-11 | Abbvie Inc. | Protein formulations and methods of making same |
TWI661833B (zh) * | 2007-11-30 | 2019-06-11 | 百慕達商艾伯維生物技術有限責任公司 | 蛋白質調配物及製造其之方法 |
EP2242875A4 (fr) * | 2008-01-15 | 2012-04-04 | Univ British Columbia | Protéine c rs2069915 en tant que prédicteur de réponse de survie et administration de protéine c ou d'un composé de type protéine c activé |
RU2011126338A (ru) * | 2008-11-28 | 2013-01-10 | Эбботт Лэборетриз | Стабильные композиции антител и способы их стабилизации |
WO2012068519A2 (fr) | 2010-11-19 | 2012-05-24 | Sirius Genomics Inc. | Marqueurs associés à la réponse à une administration de la protéine c activée, et leurs utilisations |
WO2012149197A2 (fr) | 2011-04-27 | 2012-11-01 | Abbott Laboratories | Procédé de contrôle du profil de galactosylation de protéines exprimées de manière recombinante |
EP2834635A4 (fr) | 2012-04-03 | 2015-09-02 | Smiths Medical Asd Inc | Compositions d'agents de charge d'héparine et procédés associés |
WO2013158279A1 (fr) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Procédés de purification de protéines pour réduire des espèces acides |
WO2013158273A1 (fr) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Procédés de modulation de la distribution de variant de lysine c-terminal |
US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
US9249182B2 (en) | 2012-05-24 | 2016-02-02 | Abbvie, Inc. | Purification of antibodies using hydrophobic interaction chromatography |
CN104394883B (zh) | 2012-07-04 | 2017-05-31 | 悉尼大学 | 炎性皮肤病症的治疗 |
US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
US9206390B2 (en) | 2012-09-02 | 2015-12-08 | Abbvie, Inc. | Methods to control protein heterogeneity |
WO2014143205A1 (fr) | 2013-03-12 | 2014-09-18 | Abbvie Inc. | Anticorps humains qui se lient au tnf-alpha et leurs procédés de préparation |
WO2014151878A2 (fr) | 2013-03-14 | 2014-09-25 | Abbvie Inc. | Procédés pour la modulation des profils de glycosylation de protéines de traitements à base de protéines recombinantes au moyen de monosaccharides et d'oligosaccharides |
US8921526B2 (en) | 2013-03-14 | 2014-12-30 | Abbvie, Inc. | Mutated anti-TNFα antibodies and methods of their use |
US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
WO2015051293A2 (fr) | 2013-10-04 | 2015-04-09 | Abbvie, Inc. | Utilisation d'ions métalliques pour moduler les profils de glycosylation des protéines dans le cas de protéines recombinées |
US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
US8946395B1 (en) | 2013-10-18 | 2015-02-03 | Abbvie Inc. | Purification of proteins using hydrophobic interaction chromatography |
US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
WO2015073884A2 (fr) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Compositions de protéines de liaison génétiquement glycomodifiées |
CA2946028C (fr) | 2014-04-16 | 2022-10-11 | Zz Biotech Llc | Traitement de cicatrices cutanees anormales |
US11058750B2 (en) | 2015-12-03 | 2021-07-13 | Mor Research Applications Ltd. | Compositions and methods for treatment of ocular diseases |
PL3463308T3 (pl) * | 2016-06-01 | 2022-03-14 | Servier IP UK Limited | Preparaty poli(tlenku alkilenu)-asparaginazy oraz sposoby ich wytwarzania i zastosowania |
CN108159399B (zh) * | 2017-12-29 | 2020-07-24 | 华中科技大学同济医学院附属同济医院 | 一种凝血蛋白酶aPC在防治糖尿病心肌病药物中的应用 |
WO2023119230A1 (fr) | 2021-12-22 | 2023-06-29 | L'oreal | Compositions de modulation de la voie de coagulation et de la voie de nicotinamide-adénine dinucléotide et leurs procédés d'utilisation |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4775624A (en) * | 1985-02-08 | 1988-10-04 | Eli Lilly And Company | Vectors and compounds for expression of human protein C |
US4849403A (en) * | 1985-05-29 | 1989-07-18 | Pentapharm Ag | Protein C activator, methods of preparation and use thereof |
US5516650A (en) | 1985-06-27 | 1996-05-14 | Zymogenetics, Inc. | Production of activated protein C |
AT399095B (de) * | 1986-03-27 | 1995-03-27 | Vukovich Thomas Dr | Verfahren zur auftrennung von proteinen mittels gradientenelution und vorrichtung zur durchführung des verfahrens |
US5175087A (en) * | 1987-07-06 | 1992-12-29 | Biopool International, Inc. | Method of performing tissue plasminogen activator assay |
CA1329760C (fr) * | 1987-10-29 | 1994-05-24 | Ted C. K. Lee | Formulation de plasma et de proteines recombinantes dans des milieux a grande force ionique |
US4877608A (en) * | 1987-11-09 | 1989-10-31 | Rorer Pharmaceutical Corporation | Pharmaceutical plasma protein formulations in low ionic strength media |
US4992373A (en) * | 1987-12-04 | 1991-02-12 | Eli Lilly And Company | Vectors and compounds for direct expression of activated human protein C |
JP2739050B2 (ja) * | 1988-01-28 | 1998-04-08 | ヘキスト薬品工業株式会社 | 抗血液凝固剤 |
JPH01226900A (ja) * | 1988-03-08 | 1989-09-11 | Green Cross Corp:The | プロテインcの精製方法 |
DE3823519A1 (de) * | 1988-07-12 | 1990-01-18 | Basf Ag | Verfahren zur reinigung von aktiviertem protein c |
US4981952A (en) * | 1988-10-04 | 1991-01-01 | Eli Lilly And Company | Method for the purification of vitamin K-dependent proteins |
US5093117A (en) * | 1989-01-24 | 1992-03-03 | Baxter International Inc. | Compositions and method for the treatment or prophylaxis of sepsis or septic shock |
JPH05506354A (ja) * | 1990-02-09 | 1993-09-22 | ザイモジェネティクス,インコーポレイティド | 端が切り取られた軽鎖を有する活性プロテインc |
IL97312A (en) * | 1990-02-23 | 1999-01-26 | Lilly Co Eli | A method of generating a polypeptide in an eukaryotic vector AND recombinant surrogate cell containing an enhanced transcriptional control unit based on the primary late adenovirus coefficient |
US5040862A (en) | 1990-05-07 | 1991-08-20 | Corning Incorporated | Method of trimming optical power |
AT402262B (de) * | 1991-06-20 | 1997-03-25 | Immuno Ag | Arzneimittel enthaltend aktiviertes protein c |
US5413732A (en) * | 1991-08-19 | 1995-05-09 | Abaxis, Inc. | Reagent compositions for analytical testing |
MY110664A (en) | 1992-05-21 | 1999-01-30 | Lilly Co Eli | Protein c derivatives |
DE4234295A1 (de) * | 1992-10-12 | 1994-04-14 | Thomae Gmbh Dr K | Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
US5395923A (en) * | 1993-02-23 | 1995-03-07 | Haemacure-Biotech, Inc. | Process for the obtention of a biological adhesive made of concentrated coagulation factors by "salting-out" |
JP3043558B2 (ja) * | 1993-10-29 | 2000-05-22 | 財団法人化学及血清療法研究所 | ヒト活性化プロテインc調製物及びその製法 |
JP2886061B2 (ja) * | 1993-10-29 | 1999-04-26 | 財団法人化学及血清療法研究所 | プロテインcもしくは活性化プロテインcの安定化方法及び安定化組成物 |
JPH07165605A (ja) * | 1993-12-16 | 1995-06-27 | Teijin Ltd | 活性化プロテインcバイアル |
NZ270271A (en) * | 1994-01-05 | 1996-07-26 | Lilly Co Eli | Minimizing protein c degradation |
JPH08301786A (ja) * | 1995-05-11 | 1996-11-19 | Mochida Pharmaceut Co Ltd | 吸収性骨疾患予防・治療剤 |
WO1997020043A1 (fr) | 1995-11-30 | 1997-06-05 | Zymogenetics, Inc. | Production de proteine c chez des animaux transgeniques |
EA002149B1 (ru) | 1997-04-28 | 2001-12-24 | Эли Лилли Энд Компани | Улучшенные способы приготовления активированного белка с |
HUP0001237A3 (en) | 1997-10-20 | 2002-01-28 | Lilly Co Eli | Methods for treating vascular disorders |
-
1998
- 1998-04-24 EA EA199900980A patent/EA002149B1/ru not_active IP Right Cessation
- 1998-04-24 AR ARP980101908A patent/AR012010A1/es active IP Right Grant
- 1998-04-24 CN CNB988063824A patent/CN1227025C/zh not_active Expired - Fee Related
- 1998-04-24 HU HU0003401A patent/HUP0003401A3/hu unknown
- 1998-04-24 CO CO98022609A patent/CO4950523A1/es unknown
- 1998-04-24 IL IL13232598A patent/IL132325A/xx not_active IP Right Cessation
- 1998-04-24 JP JP54721998A patent/JP4383546B2/ja not_active Expired - Fee Related
- 1998-04-24 UA UA99105884A patent/UA55448C2/uk unknown
- 1998-04-24 CO CO98022605A patent/CO4940438A1/es unknown
- 1998-04-24 CZ CZ0381099A patent/CZ298429B6/cs not_active IP Right Cessation
- 1998-04-24 PL PL98336420A patent/PL195642B1/pl unknown
- 1998-04-24 ID IDW991254A patent/ID23172A/id unknown
- 1998-04-24 AU AU71618/98A patent/AU740753C/en not_active Ceased
- 1998-04-24 JP JP54722198A patent/JP4383547B2/ja not_active Expired - Lifetime
- 1998-04-24 CN CNB988045672A patent/CN1235638C/zh not_active Expired - Fee Related
- 1998-04-24 PL PL98336889A patent/PL195090B1/pl not_active IP Right Cessation
- 1998-04-24 KR KR10-1999-7009933A patent/KR100450856B1/ko not_active IP Right Cessation
- 1998-04-24 CA CA2288143A patent/CA2288143C/fr not_active Expired - Fee Related
- 1998-04-24 NZ NZ337828A patent/NZ337828A/en unknown
- 1998-04-24 PE PE1998000309A patent/PE86299A1/es not_active Application Discontinuation
- 1998-04-24 UA UA99105788A patent/UA73071C2/uk unknown
- 1998-04-24 TR TR1999/02631T patent/TR199902631T2/xx unknown
- 1998-04-24 US US09/065,975 patent/US6159468A/en not_active Expired - Lifetime
- 1998-04-24 US US09/065,872 patent/US6162629A/en not_active Expired - Lifetime
- 1998-04-24 CA CA002287267A patent/CA2287267C/fr not_active Expired - Fee Related
- 1998-04-24 WO PCT/US1998/008384 patent/WO1998048822A1/fr not_active Application Discontinuation
- 1998-04-24 HU HU0100284A patent/HU224826B1/hu not_active IP Right Cessation
- 1998-04-24 BR BRPI9809304-5A patent/BR9809304B1/pt not_active IP Right Cessation
- 1998-04-24 ZA ZA9803496A patent/ZA983496B/xx unknown
- 1998-04-24 KR KR1019997009835A patent/KR100564189B1/ko not_active IP Right Cessation
- 1998-04-24 TR TR1999/02529T patent/TR199902529T2/xx unknown
- 1998-04-24 AR ARP980101909A patent/AR015598A1/es active IP Right Grant
- 1998-04-24 AU AU72589/98A patent/AU743531B2/en not_active Ceased
- 1998-04-24 ZA ZA9803497A patent/ZA983497B/xx unknown
- 1998-04-24 IL IL13250298A patent/IL132502A0/xx unknown
- 1998-04-24 WO PCT/US1998/008386 patent/WO1998048818A1/fr active IP Right Grant
- 1998-04-24 BR BR9809292-8A patent/BR9809292A/pt not_active Application Discontinuation
- 1998-04-24 NZ NZ500346A patent/NZ500346A/en unknown
- 1998-04-24 EA EA199900979A patent/EA004881B1/ru not_active IP Right Cessation
- 1998-04-24 ID IDW991133A patent/ID22933A/id unknown
- 1998-04-24 PE PE1998000311A patent/PE84799A1/es not_active Application Discontinuation
- 1998-04-26 EG EG45198A patent/EG23685A/xx active
- 1998-04-27 IN IN751CA1998 patent/IN183798B/en unknown
- 1998-04-27 MY MYPI98001900A patent/MY118591A/en unknown
- 1998-04-27 SV SV1998000050A patent/SV1998000050A/es not_active Application Discontinuation
- 1998-04-27 SV SV1998000051A patent/SV1998000051A/es not_active Application Discontinuation
- 1998-04-27 MY MYPI98001899A patent/MY120984A/en unknown
- 1998-04-27 IN IN752CA1998 patent/IN187157B/en unknown
- 1998-04-28 ES ES98303311T patent/ES2234072T3/es not_active Expired - Lifetime
- 1998-04-28 DE DE69828330T patent/DE69828330T2/de not_active Expired - Lifetime
- 1998-04-28 SI SI9830752T patent/SI0875252T1/xx unknown
- 1998-04-28 EP EP98303311A patent/EP0875252B1/fr not_active Expired - Lifetime
- 1998-04-28 TW TW087106558A patent/TWI242443B/zh not_active IP Right Cessation
- 1998-04-28 EP EP98303312A patent/EP0875563A3/fr not_active Withdrawn
- 1998-04-28 PT PT98303311T patent/PT875252E/pt unknown
- 1998-04-28 TW TW087106549A patent/TW585871B/zh not_active IP Right Cessation
- 1998-04-28 DK DK98303311T patent/DK0875252T3/da active
- 1998-04-28 AT AT98303311T patent/ATE285788T1/de not_active IP Right Cessation
-
1999
- 1999-04-08 HK HK99101418A patent/HK1016472A1/xx not_active IP Right Cessation
- 1999-10-21 NO NO995134A patent/NO995134L/no not_active Application Discontinuation
- 1999-10-25 NO NO995198A patent/NO995198L/no not_active Application Discontinuation
-
2000
- 2000-09-14 US US09/662,232 patent/US6395270B1/en not_active Expired - Lifetime
- 2000-09-21 US US09/667,570 patent/US6436397B1/en not_active Expired - Lifetime